The Experts below are selected from a list of 19554 Experts worldwide ranked by ideXlab platform

E.d. Van Asselt - One of the best experts on this subject based on the ideXlab platform.

  • Prioritization of Chemical Hazards in spices and herbs for European monitoring programs
    Food Control, 2018
    Co-Authors: E.d. Van Asselt, J.l. Banach, H.j. Van Der Fels-klerx
    Abstract:

    Monitoring programs are preferably risk-based, which allows focusing on the most relevant human health risks. In this study, a risk matrix was used to identify those Chemical Hazards that have the highest human health risk for the following spices and herbs: paprika/chilli powder, black pepper, nutmeg, basil, thyme, and parsley. Both the probability of occurrence and the severity of the hazard were assessed for 36 Chemical compounds and classified into low, medium, high, and severe. Probability of occurrence was evaluated based on available monitoring data and RASFF notifications as well as possibilities for economic adulteration. Severity was assessed based on available toxicological reference values and classification of carcinogenicity. The results demonstrated that the mycotoxins aflatoxins and ochratoxin A, the pesticides chlorpyrifos and triazophos, and the dye Sudan I posed the highest human health risk for spices and herbs. These compounds should, therefore, have an increased monitoring frequency in these products.

  • T2-01 A Method for Prioritizing Chemical Hazards in Food applied to Antibiotics : Technical Sessions - Microbial Food Spoilage, Pathogens, Food Defense
    2014
    Co-Authors: E.d. Van Asselt, M.y. Noordam, M.g. Pikkemaat, M. Van Der Spiegel, H.j. Van Der Fels
    Abstract:

    Introduction: Part of risk based control is the prioritization of hazard-food combinations for monitoring food safety. There are currently many methods for ranking microbial Hazards ranging from quantitative to qualitative methods, but there is hardly any information available for prioritizing Chemical Hazards. However, ranking Chemical Hazards may be performed along the same lines. Purpose: The aim of the current study was to develop a method for risk ranking of Chemical food safety Hazards using a structured and transparent approach. Methods: A semi-quantitative method was used, consisting of three steps. First, the case study was defined, determining the food groups/products to be included in the study as well as the (group of) Chemical Hazards. Then, scores were attributed to severity and probability of the hazard. Finally, these scores were multiplied to determine which food-hazard combinations have the highest priority for monitoring. Results: The method was tested in a case study on antibiotics. Severity of the hazard was scored using the Acceptable Daily Intake (ADI) as well as a score on the severity of antimicrobial resistance. Probability of the hazard depended on the amount of product consumed and on the amount of antibiotics used in animals as well as evidence of residues found. Based on the scoring of these elements, antibiotics could be ranked for the products studied. The method showed that antibiotics most relevant for monitoring were product specific. Overall, nitrofurans were amongst the most important antibiotics to be included in monitoring. Significance: The developed method is a transparent and objective method for prioritizing Chemical Hazards. The method has been applied for antibiotics, but may be applicable for other hazard-food combinations as well.

Robert H Poppenga - One of the best experts on this subject based on the ideXlab platform.

  • commercial and industrial Chemical Hazards for ruminants an update
    Veterinary Clinics of North America-food Animal Practice, 2020
    Co-Authors: Robert H Poppenga, Stephen B Hooser
    Abstract:

    Livestock can be exposed to a wide variety of commercial or industrial Chemicals that have variable toxicity. Adverse effects can be due to acute or chronic illnesses and deaths or due to contamination of meat or milk intended for human consumption. A diagnosis can be challenging in the absence of a known exposure. It is critical that a complete evaluation be conducted and appropriate samples be collected for possible analysis. Appropriate experts and regulatory agencies should be consulted as soon as possible to avoid potential contaminated animal products reaching consumers.

  • commercial and industrial Chemical Hazards for ruminants
    Veterinary Clinics of North America-food Animal Practice, 2011
    Co-Authors: Robert H Poppenga
    Abstract:

    There are many potentially hazardous commercial or industrial products used in or around ruminant environments. Although some products are highly toxic, their proper storage and use minimize their hazard to ruminants. Although most exposures to such materials occur via ingestion, inhalation or dermal exposures also are possible. The diagnosis of intoxication requires both thorough antemortem and postmortem examination of affected animals and thorough investigation of their environment. Fortunately, intoxications from such materials are relatively infrequent. The possibility of residues affecting meat or milk from exposed animals always needs to be considered.

Magnus Bengtsson - One of the best experts on this subject based on the ideXlab platform.

  • Chemical Hazards associated with treatment of waste electrical and electronic equipment
    Waste Management, 2011
    Co-Authors: Oyuna Tsydenova, Magnus Bengtsson
    Abstract:

    This review paper summarizes the existing knowledge on the Chemical Hazards associated with recycling and other end-of-life treatment options of waste electrical and electronic equipment (e-waste). The Hazards arise from the presence of heavy metals (e.g., mercury, cadmium, lead, etc.), flame retardants (e.g., pentabromophenol, polybrominated diphenyl ethers (PBDEs), tetrabromobisphenol-A (TBBPA), etc.) and other potentially harmful substances in e-waste. If improperly managed, the substances may pose significant human and environmental health risks. The review describes the potentially hazardous content of e-waste, examines the existing e-waste management practices and presents scientific data on human exposure to Chemicals, workplace and environmental pollution associated with the three major e-waste management options, i.e., recycling, incineration and landfilling. The existing e-waste management practices and associated Hazards are reviewed separately for developed and developing countries. Finally, based on this review, the paper identifies gaps in the existing knowledge and makes some recommendations for future research.

Saer Samanipour - One of the best experts on this subject based on the ideXlab platform.

  • machine learning combined with non targeted lc hrms analysis for a risk warning system of Chemical Hazards in drinking water a proof of concept
    Talanta, 2019
    Co-Authors: Saer Samanipour, Sarit Kaserzon, Soumini Vijayasarathy, Hui Jiang, Phil M Choi, Malcolm J Reid, Jochen F Mueller, Kevin V Thomas
    Abstract:

    Guaranteeing clean drinking water to the global population is becoming more challenging, because of the cases of water scarcity across the globe, growing population, and increased Chemical footprint of this population. Existing targeted strategies for hazard monitoring in drinking water are not adequate to handle such diverse and multidimensional stressors. In the current study, we have developed, validated, and tested a machine learning algorithm based on the data produced via non-targeted liquid chromatography coupled with high resolution mass spectrometry (LC-HRMS) for the identification of potential Chemical Hazards in drinking water. The machine learning algorithm consisted of a composite statistical model including an unsupervised component (i.e. principal component analysis PCA) and a supervised one (i.e. partial least square discrimination analysis PLS-DA). This model was trained using a training set of 20 drinking water samples previously tested via conventional suspect screening. The developed model was validated using a validation set of 20 drinking water samples of which 4 were spiked with 15 labeled standards at four different concentration levels. The model successfully detected all of the added analytes in the four spiked samples without producing any cases of false detection. The same validation set was processed via conventional trend analysis in order to cross validate the composite model. The results of cross validation showed that even though the conventional trend analysis approach produced a false positive detection rate of ≤5% the composite model outperformed that approach by producing zero cases of false detection. Additionally, the validated model went through an additional test with 42 extra drinking water samples from the same source for an unbiased examination of the model. Finally, the potentials and limitations of this approach were further discussed.

Daria Pakulska - One of the best experts on this subject based on the ideXlab platform.

  • Chemical Hazards arising from shale gas extraction
    Medycyna pracy, 2015
    Co-Authors: Daria Pakulska
    Abstract:

    The development of the shale industry is gaining momentum and hence the analysis of Chemical Hazards to the environment and health of the local population is extreiely timely and important. Chemical Hazards are created during the exploitation of all minerals, but in the case of shale gas production, there is much more uncertainty as regards to the effects of new technologies application. American experience suggests the increasing risk of environmental contamination, mainly groundwater. The greatest, concern is the incomplete knowledge of the composition of fluids used for fracturing shale rock and unpredictability of long-term effects of hydraulic fracturing for the environment and health of residents. High population density in the old continent causes the problem of Chemical Hazards which is much larger than in the USA. Despite the growing public discontent data on this subject are limited. First of all, there is no epidemiological studies to assess the relationship between risk factors, such as air and water pollution, and health effects in populations living in close proximity to gas wells. The aim of this article is to identify and discuss existing concepts on the sources of environmental contamination, an indication of the environment elements under pressure and potential health risks arising from shale gas extraction.

  • Chemical Hazards arising from shale gas extraction
    Medycyna Pracy, 2015
    Co-Authors: Daria Pakulska
    Abstract:

    „Identyfikacja problemow zdrowotnych związanych z wydobywaniem gazu lupkowego i analiza stanu prawnego eksploatacji gazu lupkowego w krajach UE oraz w USA i w Kanadzie”. The Ministry of Science and Higher Education