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Krystyna Skalicka-woźniak - One of the best experts on this subject based on the ideXlab platform.
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Bioactivity of essential oils extracted from Cupressus macrocarpa branchlets and Corymbia citriodora leaves grown in Egypt.
BMC complementary and alternative medicine, 2018Co-Authors: Mohamed Z. M. Salem, Hosam O. Elansary, Hayssam M. Ali, Ahmed A. El-settawy, Mohamed Soliman Elshikh, Eslam M. Abdel-salam, Krystyna Skalicka-woźniakAbstract:Cupressus macrocarpa Hartw and Corymbia citriodora (Hook.) K.D. Hill & L.A.S. Johnson, widely grown in many subtropical areas, are used for commercial purposes, such as in perfumery, cosmetics, and room fresheners. Their potential as a source of antimicrobial compounds may be useful in different applications. The chemical composition of essential oils (EOs) from C. macrocarpa branchlets and C. citriodora leaves was analyzed by using gas chromatography–mass spectrometry (GC/MS). Antibacterial and antifungal activities were assessed by the micro-dilution method to determine the minimum inhibitory concentrations (MICs), and minimum fungicidal concentrations (MFCs), and minimum bactericidal concentrations (MBCs). Further, the antioxidant capacity of the EOs was determined via 2,2′-diphenypicrylhydrazyl (DPPH) and β-carotene-linoleic acid assays. Terpinen-4-ol (23.7%), α-phellandrene (19.2%), α-citronellol (17.3%), and Citronellal were the major constituents of EO from C. macrocarpa branchlets, and α-Citronellal (56%), α-citronellol (14.7%), citronellol acetate (12.3%), isopulegol, and eucalyptol were the primary constituents of EO from C. citriodora leaves. Antibacterial activity with MIC values of EO from C. citriodora leaves was ranged from 0.06 mg/mL to 0.20 mg/mL, and MBC from 0.12 mg/mL against E. coli to 0.41 mg/mL. EO from C. macrocarpa branchlets showed less activity against bacterial strains. The MIC values against tested fungi of the EO from C. citriodora ranged from 0.11 to 0.52 mg/mL while for EO from C. macrocarpa from 0.29 to 3.21 mg/mL. The MIC and MFC values of EOs against P. funiculosum were lower than those obtained from Ketoconazole (KTZ) (0.20; 0.45; 0.29 and 0.53 mg/mL, respectively, vs 0.21 and 0.41 mg/mL. Antioxidant activity of the EO from C. citriodora was higher than that of the positive control but lower than that of the standard butylhydroxytoluene (BHT) (IC50 = 5.1 ± 0.1 μg/mL). The results indicate that the EO from Egyptian trees such as C. citriodora leaves may possesses strong bactericidal and fungicidal activities and can be used as an agrochemical for controlling plant pathogens and in human disease management which will add crop additive value.
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Bioactivity of essential oils extracted from Cupressus macrocarpa branchlets and Corymbia citriodora leaves grown in Egypt
BMC Complementary and Alternative Medicine, 2018Co-Authors: Mohamed Z. M. Salem, Hosam O. Elansary, Hayssam M. Ali, Ahmed A. El-settawy, Mohamed Soliman Elshikh, Eslam M. Abdel-salam, Krystyna Skalicka-woźniakAbstract:Background Cupressus macrocarpa Hartw and Corymbia citriodora (Hook.) K.D. Hill & L.A.S. Johnson, widely grown in many subtropical areas, are used for commercial purposes, such as in perfumery, cosmetics, and room fresheners. Their potential as a source of antimicrobial compounds may be useful in different applications. Methods The chemical composition of essential oils (EOs) from C. macrocarpa branchlets and C. citriodora leaves was analyzed by using gas chromatography–mass spectrometry (GC/MS). Antibacterial and antifungal activities were assessed by the micro-dilution method to determine the minimum inhibitory concentrations (MICs), and minimum fungicidal concentrations (MFCs), and minimum bactericidal concentrations (MBCs). Further, the antioxidant capacity of the EOs was determined via 2,2′-diphenypicrylhydrazyl (DPPH) and β -carotene-linoleic acid assays. Results Terpinen-4-ol (23.7%), α-phellandrene (19.2%), α -citronellol (17.3%), and Citronellal were the major constituents of EO from C. macrocarpa branchlets, and α -Citronellal (56%), α -citronellol (14.7%), citronellol acetate (12.3%), isopulegol, and eucalyptol were the primary constituents of EO from C. citriodora leaves. Antibacterial activity with MIC values of EO from C. citriodora leaves was ranged from 0.06 mg/mL to 0.20 mg/mL, and MBC from 0.12 mg/mL against E. coli to 0.41 mg/mL. EO from C. macrocarpa branchlets showed less activity against bacterial strains. The MIC values against tested fungi of the EO from C. citriodora ranged from 0.11 to 0.52 mg/mL while for EO from C. macrocarpa from 0.29 to 3.21 mg/mL. The MIC and MFC values of EOs against P. funiculosum were lower than those obtained from Ketoconazole (KTZ) (0.20; 0.45; 0.29 and 0.53 mg/mL, respectively, vs 0.21 and 0.41 mg/mL. Antioxidant activity of the EO from C. citriodora was higher than that of the positive control but lower than that of the standard butylhydroxytoluene (BHT) (IC_50 = 5.1 ± 0.1 μg/mL). Conclusion The results indicate that the EO from Egyptian trees such as C. citriodora leaves may possesses strong bactericidal and fungicidal activities and can be used as an agrochemical for controlling plant pathogens and in human disease management which will add crop additive value.
Eder J Lenardao - One of the best experts on this subject based on the ideXlab platform.
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evaluation of potential use of cymbopogon sp essential oils r Citronellal and n citronellylamine in cancer chemotherapy
International Journal of Applied Research in Natural Products, 2013Co-Authors: S C Stone, Raquel G Jacob, Eder J Lenardao, F A Vasconcellos, R Do C Amaral, F Leivas P LeiteAbstract:Summary. Essential oil of Cymbopogon citratus (lemongrass) and Cymbopogon nardus (citronella), as well as the monoterpenic aldehyde Citronellal and its chemically modified product, C37A ( N -citronellylamine), were evaluate for their cytotoxic potential. Two cell lines were used, a breast cancer cell line (MCF-7 - ATCC HTB-22) and a non-tumorigenic cell line (Vero - ATCC CRL-1586). Using the crystal violet assay for evaluate cell viability, we observed that all tested compounds demonstrated cytotoxicity for both cell lines, however with different intensities. Lemongrass oil was cytotoxic in similar way for both cell lines, while the others presented higher cytotoxic response to the tumor cell MCF-7, being Citronellal a high selective product. The chemical modification of Citronellal, that originated the C37A, promoted higher cytotoxic effects but no selectivity. Industrial relevance. The Cymbopogon genus has demonstrated important health feature. Essential oil of lemongrass, a plant of this genus, shows antitumor properties; however, the essential oil of citronella, a close related plant, does not have similar activity known, as well as its monoterpenic aldehyde component, Citronellal. Here we show the potential of these products, especially Citronellal, as possible new candidates for further investigation for breast cancer therapy. Keywords. Breast cancer; Citronellal, essential oil; N -citronellylamine; medicinal plants
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further analysis of the antimicrobial activity of α phenylseleno Citronellal and α phenylseleno citronellol
Food Control, 2012Co-Authors: Francine N Victoria, Raquel G Jacob, Gelson Perin, Catia S Radatz, Maraisa Sachini, Diego Alves, Lucielli Savegnago, Amanda De Souza Da Motta, Wladimir Padilha Da Silva, Eder J LenardaoAbstract:In this work we performed studies on the antimicrobial activities of α-phenylseleno Citronellal and α-phenylseleno citronellol, two new selenium-containing citronella oil derivatives. The presence of phenylselenium group in the Citronellal molecule increased antimicrobial activity, as compared to a natural, unsubstituted terpene. We assessed the antimicrobial activity of each compound against three important species of foodborne pathogenic bacteria: Listeria monocytogenes, Staphylococcus aureus and Salmonella Typhimurium, using the agar diffusion method and by measuring the minimum inhibitory concentration, all the tested compounds showed antimicrobial activity against the three bacteria used. The modified aldehyde showed good values of a minimum inhibitory concentration of 0.03 mM and antimicrobial activity against Salmonella Typhimurium at 6.400 arbitrary units per milliliter (AU/mL). The identification of the antimicrobial properties of compounds derived from citronella suggests that the use of these substances to protect food against pathogenic bacteria deserves further exploration.
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clean and atom economic synthesis of octahydroacridines application to essential oil of citronella
Tetrahedron Letters, 2003Co-Authors: Raquel G Jacob, Gelson Perin, Giancarlo V Botteselle, Eder J LenardaoAbstract:Abstract A green and efficient method for the synthesis of octahydroacridine (OHA) has been developed by a simple one-pot hetero-Diels–Alder reaction starting from (+)-Citronellal and N -arylamines in the presence of a solid supported catalyst (SiO 2 /ZnCl 2 ), under MW irradiation and without any solvent. The method was used in the direct preparation of OHA from citronella oil in good yield.
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green synthesis of isopulegol from Citronellal application to essential oil of citronella
Tetrahedron Letters, 2003Co-Authors: Raquel G Jacob, Gelson Perin, Leticia N Loi, Claudia S Pinno, Eder J LenardaoAbstract:A simple green and efficient method has been developed for the synthesis of (−)-isopulegol from (+)-Citronellal in the presence of a solid supported catalyst (SiO2/ZnCl2), under solvent-free conditions and MW irradiation. It was also found that the same technology is applicable to the direct preparation of (−)-isopulegol from the essential oil of citronella (Cymbopogon nardus, growing in southern Brazil) in excellent yield.
Mohamed Z. M. Salem - One of the best experts on this subject based on the ideXlab platform.
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Bioactivity of essential oils extracted from Cupressus macrocarpa branchlets and Corymbia citriodora leaves grown in Egypt.
BMC complementary and alternative medicine, 2018Co-Authors: Mohamed Z. M. Salem, Hosam O. Elansary, Hayssam M. Ali, Ahmed A. El-settawy, Mohamed Soliman Elshikh, Eslam M. Abdel-salam, Krystyna Skalicka-woźniakAbstract:Cupressus macrocarpa Hartw and Corymbia citriodora (Hook.) K.D. Hill & L.A.S. Johnson, widely grown in many subtropical areas, are used for commercial purposes, such as in perfumery, cosmetics, and room fresheners. Their potential as a source of antimicrobial compounds may be useful in different applications. The chemical composition of essential oils (EOs) from C. macrocarpa branchlets and C. citriodora leaves was analyzed by using gas chromatography–mass spectrometry (GC/MS). Antibacterial and antifungal activities were assessed by the micro-dilution method to determine the minimum inhibitory concentrations (MICs), and minimum fungicidal concentrations (MFCs), and minimum bactericidal concentrations (MBCs). Further, the antioxidant capacity of the EOs was determined via 2,2′-diphenypicrylhydrazyl (DPPH) and β-carotene-linoleic acid assays. Terpinen-4-ol (23.7%), α-phellandrene (19.2%), α-citronellol (17.3%), and Citronellal were the major constituents of EO from C. macrocarpa branchlets, and α-Citronellal (56%), α-citronellol (14.7%), citronellol acetate (12.3%), isopulegol, and eucalyptol were the primary constituents of EO from C. citriodora leaves. Antibacterial activity with MIC values of EO from C. citriodora leaves was ranged from 0.06 mg/mL to 0.20 mg/mL, and MBC from 0.12 mg/mL against E. coli to 0.41 mg/mL. EO from C. macrocarpa branchlets showed less activity against bacterial strains. The MIC values against tested fungi of the EO from C. citriodora ranged from 0.11 to 0.52 mg/mL while for EO from C. macrocarpa from 0.29 to 3.21 mg/mL. The MIC and MFC values of EOs against P. funiculosum were lower than those obtained from Ketoconazole (KTZ) (0.20; 0.45; 0.29 and 0.53 mg/mL, respectively, vs 0.21 and 0.41 mg/mL. Antioxidant activity of the EO from C. citriodora was higher than that of the positive control but lower than that of the standard butylhydroxytoluene (BHT) (IC50 = 5.1 ± 0.1 μg/mL). The results indicate that the EO from Egyptian trees such as C. citriodora leaves may possesses strong bactericidal and fungicidal activities and can be used as an agrochemical for controlling plant pathogens and in human disease management which will add crop additive value.
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Bioactivity of essential oils extracted from Cupressus macrocarpa branchlets and Corymbia citriodora leaves grown in Egypt
BMC Complementary and Alternative Medicine, 2018Co-Authors: Mohamed Z. M. Salem, Hosam O. Elansary, Hayssam M. Ali, Ahmed A. El-settawy, Mohamed Soliman Elshikh, Eslam M. Abdel-salam, Krystyna Skalicka-woźniakAbstract:Background Cupressus macrocarpa Hartw and Corymbia citriodora (Hook.) K.D. Hill & L.A.S. Johnson, widely grown in many subtropical areas, are used for commercial purposes, such as in perfumery, cosmetics, and room fresheners. Their potential as a source of antimicrobial compounds may be useful in different applications. Methods The chemical composition of essential oils (EOs) from C. macrocarpa branchlets and C. citriodora leaves was analyzed by using gas chromatography–mass spectrometry (GC/MS). Antibacterial and antifungal activities were assessed by the micro-dilution method to determine the minimum inhibitory concentrations (MICs), and minimum fungicidal concentrations (MFCs), and minimum bactericidal concentrations (MBCs). Further, the antioxidant capacity of the EOs was determined via 2,2′-diphenypicrylhydrazyl (DPPH) and β -carotene-linoleic acid assays. Results Terpinen-4-ol (23.7%), α-phellandrene (19.2%), α -citronellol (17.3%), and Citronellal were the major constituents of EO from C. macrocarpa branchlets, and α -Citronellal (56%), α -citronellol (14.7%), citronellol acetate (12.3%), isopulegol, and eucalyptol were the primary constituents of EO from C. citriodora leaves. Antibacterial activity with MIC values of EO from C. citriodora leaves was ranged from 0.06 mg/mL to 0.20 mg/mL, and MBC from 0.12 mg/mL against E. coli to 0.41 mg/mL. EO from C. macrocarpa branchlets showed less activity against bacterial strains. The MIC values against tested fungi of the EO from C. citriodora ranged from 0.11 to 0.52 mg/mL while for EO from C. macrocarpa from 0.29 to 3.21 mg/mL. The MIC and MFC values of EOs against P. funiculosum were lower than those obtained from Ketoconazole (KTZ) (0.20; 0.45; 0.29 and 0.53 mg/mL, respectively, vs 0.21 and 0.41 mg/mL. Antioxidant activity of the EO from C. citriodora was higher than that of the positive control but lower than that of the standard butylhydroxytoluene (BHT) (IC_50 = 5.1 ± 0.1 μg/mL). Conclusion The results indicate that the EO from Egyptian trees such as C. citriodora leaves may possesses strong bactericidal and fungicidal activities and can be used as an agrochemical for controlling plant pathogens and in human disease management which will add crop additive value.
Gaston Mougaburecueto - One of the best experts on this subject based on the ideXlab platform.
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insecticidal activity of individual and mixed monoterpenoids of geranium essential oil against pediculus humanus capitis phthiraptera pediculidae
Journal of Medical Entomology, 2012Co-Authors: A. Gallardo, Maria Ines Picollo, Paola Gonzalezaudino, Gaston MougaburecuetoAbstract:ABSTRACT The major components of geranium (Geranium maculatum L.) oil and their mixtures were tested against female Pediculus humanus capitis De Geer (Phthiraptera: Pediculidae). Chemical analysis by gas chromatography coupled to mass spectrometry revealed four major constituents: citronellol (38%), geraniol (16%), citronellyl formate (10.4%), and linalool (6.45%) (concentration expressed as percentage of total). Topical application demonstrated that the most potent component was citronellol and geraniol, with LD50 values 9.7 and 12.7 µg/insect, respectively. Linalool and Citronellyl formate were less toxic with LD50 values 24.7 and 38.5 µg/insect, respectively. Toxicity of these four major constituents in the same proportion as the natural oil, was greater than whole oil and each individual component. Removal of any four constituents produced a decreased in effectiveness. The absence of citronellol caused the greatest decrease in toxicity (DL50 from 2.2 to 10.9 µg/insect), leading us to conclude that thi...
S Ramesh - One of the best experts on this subject based on the ideXlab platform.
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yellowing and crinkling disease and its impact on the yield and composition of the essential oil of citronella cymbopogon winterianus jowitt
Flavour and Fragrance Journal, 2004Co-Authors: B Rajeswara R Rao, A K Bhattacharya, Gopal R Mallavarapu, S RameshAbstract:A field experiment conducted for 2 consecutive years in a semi-arid tropical region of South India investi- gated the influence of yellowing and crinkling disease, caused by leaf-sucking insects, on the yield and composition of the essential oil of Cymbopogon winterianus Jowitt (citronella cv. Java 2). Infected leaves exhibited yellow specks or blotches which in later stages developed into yellow streaks running along the length of the leaves. Emerging young leaves were pale green or yellow coloured, twisted, crinkled and developed into whip-like structures. Severely diseased plants died. The yellowing and crinkling disease decreased biomass yield in the first and second years of harvesting by 62.8% and 82.7%, respectively. The corresponding decreases in essential oil yield per plant were 62.8% and 79.0%. The essential oil exam- ined by GC and GC-MS from cultivated healthy plants contained Citronellal (28.4%), geraniol (24.8%), citronellol (11.8%) and elemol (10.2%). The major components from diseased plants were geraniol (19.0-25.5%), elemol (15.3-20.4%), Citronellal (13.4-19.1%) and citronellol (12.9-15.1%). Caryophyllene oxide (3.5-6.0%) was an important minor com- ponent. Copyright © 2004 John Wiley & Sons, Ltd. fore, in the present study, the variations in biomass yield, essential oil yield and essential oil composition of citronella affected by yellowing and crinkling disease caused by leaf-sucking insects were investigated.
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essential oil composition of a citronella like variant of lemongrass
Journal of Essential Oil Research, 1997Co-Authors: R N Kulkarni, Gopal R Mallavarapu, S Ramesh, K Baskaran, Sushil KumarAbstract:Abstract A natural variant of lemongrass (Cymbopogon flexuosus), with a citronella-like odor which was isolated from cycle-4 population of a recurrent selection program in lemongrass, was studied for its essential oil composition by GC and GC/MS. The main components of the oil were geraniol (13.1%), citronellyl acetate (11.2%) and geranyl acetate (25.9%), while neral (3.7%) and geranial (5.8%) were minor constituents.