The Experts below are selected from a list of 11919 Experts worldwide ranked by ideXlab platform

Martin Tegenthoff - One of the best experts on this subject based on the ideXlab platform.

  • sustained increase of somatosensory cortex excitability by tactile Coactivation studied by paired median nerve stimulation in humans correlates with perceptual gain
    The Journal of Physiology, 2007
    Co-Authors: Oliver Hoffken, Patrick Ragert, Hubert R Dinse, Mathias Veit, Frauke Knossalla, Silke Lissek, Barbara Bliem, Martin Tegenthoff
    Abstract:

    Cortical excitability can be reliably assessed by means of paired-pulse stimulation techniques. Recent studies demonstrated particularly for motor and visual cortex that cortical excitability is systematically altered following the induction of learning processes or during the development of pathological symptoms. A recent tactile Coactivation protocol developed by Godde and coworkers showed that improvement of tactile performance in humans can be achieved also without training through passive stimulation on a time scale of a few hours. Tactile Coactivation evokes plastic changes in somatosensory cortical areas as measured by blood oxygenation level-dependent (BOLD) activation in fMRI or SEP-dipole localization, which correlated with the individual gain in performance. To demonstrate changes in excitability of somatosensory cortex after tactile Coactivation, we combined assessment of tactile performance with recordings of paired-pulse SEPs after electrical median nerve stimulation of both the right coactivated and left control hand at ISIs of 30 and 100 ms before, 3 h after and 24 h after tactile Coactivation. Amplitudes and latencies of the first and second cortical N20/P25 response components were calculated. For the coactivated hand, we found significantly lowered discrimination thresholds and significantly reduced paired-pulse ratios (second N20/P25 response/first N20/P25 response) at an ISI of 30 ms after tactile Coactivation indicating enhanced cortical excitability. No changes in paired-pulse behaviour were observed for ISIs of 100 ms. Both psychophysical and cortical effects recovered to baseline 24 h after tactile Coactivation. The individual increase of excitability correlated with the individual gain in discrimination performance. For the left control hand we found no effects of tactile Coactivation on paired-pulse behaviour and discrimination threshold. Our results indicate that changes in cortical excitability are modified by tactile Coactivation and were scaled with the degree of improvement of the individual perceptual learning. Conceivably, changes of cortical excitability seem to constitute an additional important marker and mechanism underlying plastic reorganization.

  • tactile Coactivation resets age related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • Tactile Coactivation resets age‐related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • combination of 5 hz repetitive transcranial magnetic stimulation rtms and tactile Coactivation boosts tactile discrimination in humans
    Neuroscience Letters, 2003
    Co-Authors: Patrick Ragert, Hubert R Dinse, Burkhard Pleger, Claudia Wilimzig, Elke Frombach, Peter Schwenkreis, Martin Tegenthoff
    Abstract:

    A combination of 5 Hz repetitive transcranial magnetic stimulation (rTMS) over the left primary somatosensory cortex together with tactile Coactivation applied to the right index-finger representation (coac+rTMS) boosted tactile discrimination ability tested on the right index-finger. Applying Coactivation alone caused a 0.25 mm lowering in tactile discrimination thresholds. In contrast, after coac+rTMS we found a significant further improvement of discrimination thresholds in comparison to the Coactivation-induced perceptual changes alone. We demonstrate that the individual further improvement after coac+rTMS depended on the effectiveness of the Coactivation protocol when applied alone. Subjects, who showed little gain in tactile performance after Coactivation alone, showed the largest improvement after coac+rTMS implying that the combined application was selective for poor learners. The selective effects of coac+rTMS are discussed in respect to N-methyl-d-aspartate receptor activation.

Hubert R Dinse - One of the best experts on this subject based on the ideXlab platform.

  • sustained increase of somatosensory cortex excitability by tactile Coactivation studied by paired median nerve stimulation in humans correlates with perceptual gain
    The Journal of Physiology, 2007
    Co-Authors: Oliver Hoffken, Patrick Ragert, Hubert R Dinse, Mathias Veit, Frauke Knossalla, Silke Lissek, Barbara Bliem, Martin Tegenthoff
    Abstract:

    Cortical excitability can be reliably assessed by means of paired-pulse stimulation techniques. Recent studies demonstrated particularly for motor and visual cortex that cortical excitability is systematically altered following the induction of learning processes or during the development of pathological symptoms. A recent tactile Coactivation protocol developed by Godde and coworkers showed that improvement of tactile performance in humans can be achieved also without training through passive stimulation on a time scale of a few hours. Tactile Coactivation evokes plastic changes in somatosensory cortical areas as measured by blood oxygenation level-dependent (BOLD) activation in fMRI or SEP-dipole localization, which correlated with the individual gain in performance. To demonstrate changes in excitability of somatosensory cortex after tactile Coactivation, we combined assessment of tactile performance with recordings of paired-pulse SEPs after electrical median nerve stimulation of both the right coactivated and left control hand at ISIs of 30 and 100 ms before, 3 h after and 24 h after tactile Coactivation. Amplitudes and latencies of the first and second cortical N20/P25 response components were calculated. For the coactivated hand, we found significantly lowered discrimination thresholds and significantly reduced paired-pulse ratios (second N20/P25 response/first N20/P25 response) at an ISI of 30 ms after tactile Coactivation indicating enhanced cortical excitability. No changes in paired-pulse behaviour were observed for ISIs of 100 ms. Both psychophysical and cortical effects recovered to baseline 24 h after tactile Coactivation. The individual increase of excitability correlated with the individual gain in discrimination performance. For the left control hand we found no effects of tactile Coactivation on paired-pulse behaviour and discrimination threshold. Our results indicate that changes in cortical excitability are modified by tactile Coactivation and were scaled with the degree of improvement of the individual perceptual learning. Conceivably, changes of cortical excitability seem to constitute an additional important marker and mechanism underlying plastic reorganization.

  • tactile Coactivation resets age related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • Tactile Coactivation resets age‐related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • combination of 5 hz repetitive transcranial magnetic stimulation rtms and tactile Coactivation boosts tactile discrimination in humans
    Neuroscience Letters, 2003
    Co-Authors: Patrick Ragert, Hubert R Dinse, Burkhard Pleger, Claudia Wilimzig, Elke Frombach, Peter Schwenkreis, Martin Tegenthoff
    Abstract:

    A combination of 5 Hz repetitive transcranial magnetic stimulation (rTMS) over the left primary somatosensory cortex together with tactile Coactivation applied to the right index-finger representation (coac+rTMS) boosted tactile discrimination ability tested on the right index-finger. Applying Coactivation alone caused a 0.25 mm lowering in tactile discrimination thresholds. In contrast, after coac+rTMS we found a significant further improvement of discrimination thresholds in comparison to the Coactivation-induced perceptual changes alone. We demonstrate that the individual further improvement after coac+rTMS depended on the effectiveness of the Coactivation protocol when applied alone. Subjects, who showed little gain in tactile performance after Coactivation alone, showed the largest improvement after coac+rTMS implying that the combined application was selective for poor learners. The selective effects of coac+rTMS are discussed in respect to N-methyl-d-aspartate receptor activation.

  • tactile Coactivation induced changes in spatial discrimination performance
    The Journal of Neuroscience, 2000
    Co-Authors: Ben Godde, Beate Stauffenberg, Friederike Spengler, Hubert R Dinse
    Abstract:

    We studied Coactivation-based cortical plasticity at a psychophysical level in humans. For induction of plasticity, we used a protocol of simultaneous pairing of tactile stimulation to follow as closely as possible the idea of Hebbian learning. We reported previously that a few hours of tactile Coactivation resulted in selective and reversible reorganization of receptive fields and cortical maps of the hindpaw representation of the somatosensory cortex of adult rats (Godde et al., 1996). In the present study, simultaneous spatial two-point discrimination was tested on the tip of the right index finger in human subjects as a marker of plastic changes. After 2 hr of Coactivation we found a significant improvement in discrimination performance that was reversible within 8 hr. Reduction of the duration of the Coactivation protocol revealed that 30 min was not sufficient to drive plastic changes. Repeated application of Coactivation over 3 consecutive days resulted in a delayed recovery indicating stabilization of the improvement over time. Perceptual changes were highly selective because no transfer of improved performance to fingers that were not stimulated was found. The results demonstrate the potential role of sensory input statistics (i.e., their probability of occurrence and spatiotemporal relationships) in the induction of cortical plasticity without involving cognitive factors such as attention or reinforcement.

Patrick Ragert - One of the best experts on this subject based on the ideXlab platform.

  • sustained increase of somatosensory cortex excitability by tactile Coactivation studied by paired median nerve stimulation in humans correlates with perceptual gain
    The Journal of Physiology, 2007
    Co-Authors: Oliver Hoffken, Patrick Ragert, Hubert R Dinse, Mathias Veit, Frauke Knossalla, Silke Lissek, Barbara Bliem, Martin Tegenthoff
    Abstract:

    Cortical excitability can be reliably assessed by means of paired-pulse stimulation techniques. Recent studies demonstrated particularly for motor and visual cortex that cortical excitability is systematically altered following the induction of learning processes or during the development of pathological symptoms. A recent tactile Coactivation protocol developed by Godde and coworkers showed that improvement of tactile performance in humans can be achieved also without training through passive stimulation on a time scale of a few hours. Tactile Coactivation evokes plastic changes in somatosensory cortical areas as measured by blood oxygenation level-dependent (BOLD) activation in fMRI or SEP-dipole localization, which correlated with the individual gain in performance. To demonstrate changes in excitability of somatosensory cortex after tactile Coactivation, we combined assessment of tactile performance with recordings of paired-pulse SEPs after electrical median nerve stimulation of both the right coactivated and left control hand at ISIs of 30 and 100 ms before, 3 h after and 24 h after tactile Coactivation. Amplitudes and latencies of the first and second cortical N20/P25 response components were calculated. For the coactivated hand, we found significantly lowered discrimination thresholds and significantly reduced paired-pulse ratios (second N20/P25 response/first N20/P25 response) at an ISI of 30 ms after tactile Coactivation indicating enhanced cortical excitability. No changes in paired-pulse behaviour were observed for ISIs of 100 ms. Both psychophysical and cortical effects recovered to baseline 24 h after tactile Coactivation. The individual increase of excitability correlated with the individual gain in discrimination performance. For the left control hand we found no effects of tactile Coactivation on paired-pulse behaviour and discrimination threshold. Our results indicate that changes in cortical excitability are modified by tactile Coactivation and were scaled with the degree of improvement of the individual perceptual learning. Conceivably, changes of cortical excitability seem to constitute an additional important marker and mechanism underlying plastic reorganization.

  • tactile Coactivation resets age related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • Tactile Coactivation resets age‐related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • combination of 5 hz repetitive transcranial magnetic stimulation rtms and tactile Coactivation boosts tactile discrimination in humans
    Neuroscience Letters, 2003
    Co-Authors: Patrick Ragert, Hubert R Dinse, Burkhard Pleger, Claudia Wilimzig, Elke Frombach, Peter Schwenkreis, Martin Tegenthoff
    Abstract:

    A combination of 5 Hz repetitive transcranial magnetic stimulation (rTMS) over the left primary somatosensory cortex together with tactile Coactivation applied to the right index-finger representation (coac+rTMS) boosted tactile discrimination ability tested on the right index-finger. Applying Coactivation alone caused a 0.25 mm lowering in tactile discrimination thresholds. In contrast, after coac+rTMS we found a significant further improvement of discrimination thresholds in comparison to the Coactivation-induced perceptual changes alone. We demonstrate that the individual further improvement after coac+rTMS depended on the effectiveness of the Coactivation protocol when applied alone. Subjects, who showed little gain in tactile performance after Coactivation alone, showed the largest improvement after coac+rTMS implying that the combined application was selective for poor learners. The selective effects of coac+rTMS are discussed in respect to N-methyl-d-aspartate receptor activation.

Claudia Wilimzig - One of the best experts on this subject based on the ideXlab platform.

  • Tactile Coactivation resets age‐related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • tactile Coactivation resets age related decline of human tactile discrimination
    Annals of Neurology, 2006
    Co-Authors: Hubert R Dinse, Patrick Ragert, Claudia Wilimzig, Nadine Kleibel, Tobias Kalisch, Martin Tegenthoff
    Abstract:

    Objective: For young subjects, it is well-documented that training and practice improve sensorimotor performance. However, little is known about how the typically observed age-related decline of sensorimotor abilities can be ameliorated by sensory stimulation. Methods: As an alternative approach to training, we have introduced a tactile Coactivation protocol involving Hebbian synaptic plasticity to improve tactile performance on a short timescale of a few hours. Results: By applying Coactivation on the index finger to drive perceptual learning, we demonstrate that in the elderly, aged 65 to 89 years, the age-related impairment of tactile two-point discrimination can be mitigated substantially. In elderly adults, tactile-acuity thresholds increased to 3.5mm compared with 1.5mm found in young adults, whereas 50-year-old subjects showed intermediate performance. As a result of Coactivation, discrimination thresholds of the 80-year-old adults came to match those typically found at an age of 50, demonstrating that age-related decline in tactile performance is not irreversible, but rather subject to considerable restoration by specific stimulation protocols. Interpretation: Because the preservation of sufficient tactile acuity into advanced age is an important prerequisite for the maintenance of autonomous living, we believe that the concept of Coactivation might turn out to be beneficial in preserving everyday sensorimotor competence in the elderly through new forms of therapeutic interventions.

  • combination of 5 hz repetitive transcranial magnetic stimulation rtms and tactile Coactivation boosts tactile discrimination in humans
    Neuroscience Letters, 2003
    Co-Authors: Patrick Ragert, Hubert R Dinse, Burkhard Pleger, Claudia Wilimzig, Elke Frombach, Peter Schwenkreis, Martin Tegenthoff
    Abstract:

    A combination of 5 Hz repetitive transcranial magnetic stimulation (rTMS) over the left primary somatosensory cortex together with tactile Coactivation applied to the right index-finger representation (coac+rTMS) boosted tactile discrimination ability tested on the right index-finger. Applying Coactivation alone caused a 0.25 mm lowering in tactile discrimination thresholds. In contrast, after coac+rTMS we found a significant further improvement of discrimination thresholds in comparison to the Coactivation-induced perceptual changes alone. We demonstrate that the individual further improvement after coac+rTMS depended on the effectiveness of the Coactivation protocol when applied alone. Subjects, who showed little gain in tactile performance after Coactivation alone, showed the largest improvement after coac+rTMS implying that the combined application was selective for poor learners. The selective effects of coac+rTMS are discussed in respect to N-methyl-d-aspartate receptor activation.

Philip E Martin - One of the best experts on this subject based on the ideXlab platform.

  • effects of age and walking speed on Coactivation and cost of walking in healthy adults
    Gait & Posture, 2010
    Co-Authors: Daniel S Peterson, Philip E Martin
    Abstract:

    Our goal was to determine how age and walking speed affect metabolic cost of walking (Cw), lower, extremity antagonist Coactivation, and relationships between Coactivation and Cw in healthy, active, individuals. Fourteen young (25 ± 3 years) and 14 older (71 ± 4 years) participants walked on a treadmill at, four speeds (0.89, 1.12, 1.34, and 1.57 m s−1) while electromyography (EMG) and oxygen consumption, were measured. Coactivation indices were calculated for musculature about the thigh and shank. Cw, was higher in older adults across all speeds (p < 0.001). Coactivation about the thigh was also higher in, older adults (p < 0.001), whereas Coactivation about the shank was not different between age groups (p = 0.60). Total Coactivation (thigh Coactivation plus shank Coactivation) showed significant positive, relationships to Cw at all walking speeds (r = 0.46–0.57). Higher Cw and Coactivation in older adults, along with the positive relationship between Cw and Coactivation implies Coactivation contributes to, higher Cw of older adults.

  • Effects of age and walking speed on Coactivation and cost of walking in healthy adults.
    Gait & Posture, 2010
    Co-Authors: Daniel S Peterson, Philip E Martin
    Abstract:

    Our goal was to determine how age and walking speed affect metabolic cost of walking (Cw), lower, extremity antagonist Coactivation, and relationships between Coactivation and Cw in healthy, active, individuals. Fourteen young (25 ± 3 years) and 14 older (71 ± 4 years) participants walked on a treadmill at, four speeds (0.89, 1.12, 1.34, and 1.57 m s−1) while electromyography (EMG) and oxygen consumption, were measured. Coactivation indices were calculated for musculature about the thigh and shank. Cw, was higher in older adults across all speeds (p