The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Janice Light - One of the best experts on this subject based on the ideXlab platform.
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Long-term outcomes for individuals who use augmentative and alternative communication: part II--Communicative Interaction.
Augmentative and Alternative Communication, 2007Co-Authors: Shelley K. Lund, Janice LightAbstract:This study evaluated the Communicative Interaction skills of seven young men (ages 19 – 23 years) who had used AAC systems for at least 15 years. Turn-taking patterns, use of Communicative functions, and linguistic complexity were analyzed. Current performance was compared to the participants' skills when they were preschoolers and participated in another study of Interaction skills (Light, ; Light, Collier, & Parnes, ). Results indicated that the turn distribution between partners was more equitable than it had been when the participants were preschoolers; five of the participants approached reciprocity in turn taking during at least two of the Interactions observed. During Interactions with their caregivers, the participants fulfilled most of their obligatory turns and more than half of their non-obligatory turns. The Communicative functions used most frequently by the participants were confirmations/denials and provisions of information. Three of the participants demonstrated the ability to use complet...
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long term outcomes for individuals who use augmentative and alternative communication part i what is a good outcome
Augmentative and Alternative Communication, 2006Co-Authors: Shelley K. Lund, Janice LightAbstract:Over the past 20 years, there have been many advances in the field of augmentative and alternative communication (AAC). Despite these advances, there are no data on the long-term outcomes of AAC interventions. This study evaluated the long-term outcomes for a group of seven young men (ages 19 – 23 years) who had used AAC systems for at least 15 years and were part of the first generation to have received AAC services since they were in preschool. Outcomes were measured in the following domains: (a) receptive language; (b) reading comprehension; (c) Communicative Interaction; (d) linguistic complexity; (e) functional communication; (f) educational and vocational achievement; (g) self-determination; and (h) quality of life. The outcomes for the group were diverse, with individual variations across all measures. Evaluation of the data raised many issues surrounding the challenges of outcomes measurement; these are discussed with suggestions for future research.
Jing Zhong - One of the best experts on this subject based on the ideXlab platform.
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c fos expression in the paternal mouse brain induced by Communicative Interaction with maternal mates
Molecular Brain, 2014Co-Authors: Jing Zhong, Chiharu Higashida, Shirin Akther, Mingkun Liang, Takahiro Tsuji, Haruhiro HigashidaAbstract:Appropriate parental care by fathers greatly facilitates health in human family life. Much less is known from animal studies regarding the factors and neural circuitry that affect paternal behavior compared with those affecting maternal behavior. We recently reported that ICR mouse sires displayed maternal-like retrieval behavior when they were separated from pups and caged with their mates (co-housing) because the sires receive Communicative Interactions via ultrasonic and pheromone signals from the dams. We investigated the brain structures involved in regulating this activity by quantifying c-Fos-immunoreactive cells as neuronal activation markers in the neural pathway of male parental behavior. c-Fos expression in the medial preoptic area (mPOA) was significantly higher in sires that exhibited retrieval behavior (retrievers) than those with no such behavior (non-retrievers). Identical increased expression was found in the mPOA region in the retrievers stimulated by ultrasonic vocalizations or pheromones from their mates. Such increases in expression were not observed in the ventral tegmental area (VTA), nucleus accumbens (NAcc) or ventral palladium (VP). On the following day that we identified the families of the retrievers or non-retrievers, c-Fos expression in neuronal subsets in the mPOA, VTA, NAcc and VP was much higher in the retriever sires when they isolated together with their mates in new cages. This difference was not observed in the singly isolated retriever sires in new cages. The non-retriever sires did not display expression changes in the four brain regions that were assessed. The mPOA neurons appeared to be activated by direct Communicative Interactions with mate dams, including ultrasonic vocalizations and pheromones. The mPOA-VTA-NAcc-VP neural circuit appears to be involved in paternal retrieval behavior.
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displays of paternal mouse pup retrieval following Communicative Interaction with maternal mates
Nature Communications, 2013Co-Authors: Hongxiang Liu, Olga Lopatina, Chiharu Higashida, Hiroko Fujimoto, Shirin Akther, Alena Inzhutova, Mingkun Liang, Jing Zhong, Takahiro Tsuji, Toru YoshiharaAbstract:Compared with the knowledge of maternal care, much less is known about the factors required for paternal parental care. Here we report that new sires of laboratory mice, though not spontaneously parental, can be induced to show maternal-like parental care (pup retrieval) using signals from dams separated from their pups. During this Interaction, the maternal mates emit 38-kHz ultrasonic vocalizations to their male partners, which are equivalent to vocalizations that occur following pheromone stimulation. Without these signals or in the absence of maternal mates, the sires do not retrieve their pups within 5 min. These results show that, in mice, the maternal parent communicates to the paternal parent to encourage pup care. This new paradigm may be useful in the analysis of the parental brain during paternal care induced by interactive communication.
Haruhiro Higashida - One of the best experts on this subject based on the ideXlab platform.
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communication impairment in ultrasonic vocal repertoire during the suckling period of cd157 knockout mice transient improvement by oxytocin
Frontiers in Neuroscience, 2017Co-Authors: O L Lopatina, Kazumi Furuhara, Katsuhiko Ishihara, A B Salmina, Haruhiro HigashidaAbstract:Communication consists of social Interaction, recognition, and information transmission. Communication ability is the most affected component in children with autism spectrum disorder (ASD). Recently, we reported that the CD157/BST1 gene is associated with ASD, and that CD157 knockout (Cd157−/−) mice display severe impairments in social behavior that are improved by oxytocin (OXT) treatment. Here, we sought to determine whether Cd157−/− mice can be used as a suitable model for communication deficits by measuring ultrasonic vocalizations (USVs), especially in the early developmental stage. Call number produced in pups due to isolation from dams was higher at postnatal day (PND) 3 in knockout pups than wild-type mice, but was lower at PNDs 7 and 10. Pups of both genotypes vocalized with a poorer voice repertoire at PND 3. However, although wild-type pups emitted USVs consisting of six different syllable types at PNDs 7 and 10, knockout pups vocalized with only two types. This developmental impairment in USV emission was rescued within 30 min by intraperitoneal OXT treatment, but quickly returned to control levels after 120 min, showing a transient effect of OXT. USV impairment was partially observed in Cd157+/- heterozygous mice, but not in Cd157−/− adult male mice examined while under courtship. These results demonstrate that CD157 gene deletion results in social communication insufficiencies, and suggests that CD157 is likely involved in acoustic communication. This unique OXT-sensitive developmental delay in Cd157−/− pups may be a useful model of Communicative Interaction impairment in ASD.
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c fos expression in the paternal mouse brain induced by Communicative Interaction with maternal mates
Molecular Brain, 2014Co-Authors: Jing Zhong, Chiharu Higashida, Shirin Akther, Mingkun Liang, Takahiro Tsuji, Haruhiro HigashidaAbstract:Appropriate parental care by fathers greatly facilitates health in human family life. Much less is known from animal studies regarding the factors and neural circuitry that affect paternal behavior compared with those affecting maternal behavior. We recently reported that ICR mouse sires displayed maternal-like retrieval behavior when they were separated from pups and caged with their mates (co-housing) because the sires receive Communicative Interactions via ultrasonic and pheromone signals from the dams. We investigated the brain structures involved in regulating this activity by quantifying c-Fos-immunoreactive cells as neuronal activation markers in the neural pathway of male parental behavior. c-Fos expression in the medial preoptic area (mPOA) was significantly higher in sires that exhibited retrieval behavior (retrievers) than those with no such behavior (non-retrievers). Identical increased expression was found in the mPOA region in the retrievers stimulated by ultrasonic vocalizations or pheromones from their mates. Such increases in expression were not observed in the ventral tegmental area (VTA), nucleus accumbens (NAcc) or ventral palladium (VP). On the following day that we identified the families of the retrievers or non-retrievers, c-Fos expression in neuronal subsets in the mPOA, VTA, NAcc and VP was much higher in the retriever sires when they isolated together with their mates in new cages. This difference was not observed in the singly isolated retriever sires in new cages. The non-retriever sires did not display expression changes in the four brain regions that were assessed. The mPOA neurons appeared to be activated by direct Communicative Interactions with mate dams, including ultrasonic vocalizations and pheromones. The mPOA-VTA-NAcc-VP neural circuit appears to be involved in paternal retrieval behavior.
Toru Yoshihara - One of the best experts on this subject based on the ideXlab platform.
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displays of paternal mouse pup retrieval following Communicative Interaction with maternal mates
Nature Communications, 2013Co-Authors: Hongxiang Liu, Olga Lopatina, Chiharu Higashida, Hiroko Fujimoto, Shirin Akther, Alena Inzhutova, Mingkun Liang, Jing Zhong, Takahiro Tsuji, Toru YoshiharaAbstract:Compared with the knowledge of maternal care, much less is known about the factors required for paternal parental care. Here we report that new sires of laboratory mice, though not spontaneously parental, can be induced to show maternal-like parental care (pup retrieval) using signals from dams separated from their pups. During this Interaction, the maternal mates emit 38-kHz ultrasonic vocalizations to their male partners, which are equivalent to vocalizations that occur following pheromone stimulation. Without these signals or in the absence of maternal mates, the sires do not retrieve their pups within 5 min. These results show that, in mice, the maternal parent communicates to the paternal parent to encourage pup care. This new paradigm may be useful in the analysis of the parental brain during paternal care induced by interactive communication.
Chiharu Higashida - One of the best experts on this subject based on the ideXlab platform.
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c fos expression in the paternal mouse brain induced by Communicative Interaction with maternal mates
Molecular Brain, 2014Co-Authors: Jing Zhong, Chiharu Higashida, Shirin Akther, Mingkun Liang, Takahiro Tsuji, Haruhiro HigashidaAbstract:Appropriate parental care by fathers greatly facilitates health in human family life. Much less is known from animal studies regarding the factors and neural circuitry that affect paternal behavior compared with those affecting maternal behavior. We recently reported that ICR mouse sires displayed maternal-like retrieval behavior when they were separated from pups and caged with their mates (co-housing) because the sires receive Communicative Interactions via ultrasonic and pheromone signals from the dams. We investigated the brain structures involved in regulating this activity by quantifying c-Fos-immunoreactive cells as neuronal activation markers in the neural pathway of male parental behavior. c-Fos expression in the medial preoptic area (mPOA) was significantly higher in sires that exhibited retrieval behavior (retrievers) than those with no such behavior (non-retrievers). Identical increased expression was found in the mPOA region in the retrievers stimulated by ultrasonic vocalizations or pheromones from their mates. Such increases in expression were not observed in the ventral tegmental area (VTA), nucleus accumbens (NAcc) or ventral palladium (VP). On the following day that we identified the families of the retrievers or non-retrievers, c-Fos expression in neuronal subsets in the mPOA, VTA, NAcc and VP was much higher in the retriever sires when they isolated together with their mates in new cages. This difference was not observed in the singly isolated retriever sires in new cages. The non-retriever sires did not display expression changes in the four brain regions that were assessed. The mPOA neurons appeared to be activated by direct Communicative Interactions with mate dams, including ultrasonic vocalizations and pheromones. The mPOA-VTA-NAcc-VP neural circuit appears to be involved in paternal retrieval behavior.
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displays of paternal mouse pup retrieval following Communicative Interaction with maternal mates
Nature Communications, 2013Co-Authors: Hongxiang Liu, Olga Lopatina, Chiharu Higashida, Hiroko Fujimoto, Shirin Akther, Alena Inzhutova, Mingkun Liang, Jing Zhong, Takahiro Tsuji, Toru YoshiharaAbstract:Compared with the knowledge of maternal care, much less is known about the factors required for paternal parental care. Here we report that new sires of laboratory mice, though not spontaneously parental, can be induced to show maternal-like parental care (pup retrieval) using signals from dams separated from their pups. During this Interaction, the maternal mates emit 38-kHz ultrasonic vocalizations to their male partners, which are equivalent to vocalizations that occur following pheromone stimulation. Without these signals or in the absence of maternal mates, the sires do not retrieve their pups within 5 min. These results show that, in mice, the maternal parent communicates to the paternal parent to encourage pup care. This new paradigm may be useful in the analysis of the parental brain during paternal care induced by interactive communication.