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Lawrence S Engel - One of the best experts on this subject based on the ideXlab platform.
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association between Deepwater Horizon oil spill response and cleanup work experiences and lung function
2018Co-Authors: Lawrence S Engel, Richard K Kwok, Patricia A Stewart, Mark Stenzel, Matthew D Curry, John A Mcgrath, Braxton W Jackson, Maureen Y Lichtveld, Dale P SandlerAbstract:Abstract Introduction Oil spill response and cleanup (OSRC) workers had potentially stressful experiences during mitigation efforts following the 2010 Deepwater Horizon disaster. Smelling chemicals; skin or clothing contact with oil; heat stress; handling oily plants/wildlife or dead animal recovery; and/or being out of regular work may have posed a risk to worker respiratory health through psychological stress mechanisms. Objective To evaluate the association between six potentially stressful oil spill experiences and lung function among OSRC workers 1–3 years following the Deepwater Horizon disaster, while controlling for primary oil spill inhalation hazards and other potential confounders. Methods Of 6811 GuLF STUDY participants who performed OSRC work and completed a quality spirometry test, 4806 provided information on all exposures and confounders. We carried out complete case analysis and used multiple imputation to assess risk among the larger sample. Potentially stressful work experiences were identified from an earlier study of these workers. The lung function parameters of interest include the forced expiratory volume in 1 s (FEV 1 , mL), the forced vital capacity (FVC, mL) and the ratio (FEV 1 /FVC, %). Results On average, participants in the analytic sample completed spirometry tests 1.7 years after the spill. Among workers with at least 2 acceptable FEV 1 and FVC curves, workers with jobs that involved oily plants/wildlife or dead animal recovery had lower values for FEV 1 (Mean difference: −53 mL, 95% CI: −84, −22), FVC (Mean difference: −45 mL, 95% CI: −81, −9) and FEV 1 /FVC (Mean difference: −0.44%, 95% CI: −0.80, −0.07) compared to unexposed workers in analyses using multiple imputation. Conclusions Workers involved in handling oily plants/wildlife or dead animal recovery had lower lung function than unexposed workers after accounting for other OSRC inhalation hazards.
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Deepwater Horizon oil spill exposures and neurobehavioral function in gulf study participants
2018Co-Authors: Arbor J L Quist, Richard K Kwok, Dale P Sandler, Diane S Rohlman, Patricia A Stewart, Mark Stenzel, Lawrence S EngelAbstract:Background: The 2010 Deepwater Horizon (DWH) oil spill released over 5 million barrels of crude oil and exposed tens of thousands of clean-up workers to hydrocarbons and other harmful chemicals. So...
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Deepwater Horizon oil spill exposures and nonfatal myocardial infarction in the gulf study
2018Co-Authors: Jean Strelitz, Lawrence S Engel, Richard K Kwok, Aubrey Miller, Aaron Blair, Dale P SandlerAbstract:Workers involved in the response and clean-up of the 2010 Deepwater Horizon oil spill faced possible exposures to crude oil, burning oil, dispersants and other pollutants in addition to physical and emotional stress. These exposures may have increased risk of myocardial infarction (MI) among oil spill workers. Gulf Long-term Follow-up (GuLF) STUDY participants comprise individuals who either participated in the Deepwater Horizon response efforts or registered for safety training but were not hired. Oil spill-related exposures were assessed during enrollment interviews conducted in 2011–2013. We estimated risk ratios (RR) and 95% confidence intervals for the associations of clean-up work characteristics with self-reported nonfatal MI up to three years post-spill. Among 31,109 participants without history of MI prior to the spill, 77% worked on the oil spill. There were 192 self-reported MI during the study period; 151 among workers. Among the full cohort, working on the oil spill clean-up (vs not working on the clean-up) and living in proximity to the oil spill (vs further away) were suggestively associated with a possible increased risk of nonfatal MI [RR: 1.22 (0.86, 1.73) and 1.15 (0.82, 1.60), respectively]. Among oil spill workers, working for > 180 days was associated with MI [RR for > 180 days (vs 1–30 days): 2.05 (1.05, 4.01)], as was stopping working due to heat [RR: 1.99 (1.43, 2.78)]. There were suggestive associations of maximum total hydrocarbon exposure ≥3.00 ppm (vs 180 days and stopping work due to heat increased risk of nonfatal MI. Future research should evaluate whether the observed associations are related to specific chemical exposures or other stressors associated with the spill.
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exposure to oil spill chemicals and lung function in Deepwater Horizon disaster response workers
2018Co-Authors: Richard K Kwok, Lawrence S Engel, Patricia A Stewart, Mark Stenzel, Matthew D Curry, John A Mcgrath, Braxton W Jackson, Robert L Jensen, Maureen Y Lichtveld, Aubrey MillerAbstract:Objective:The aim of this study was to assess the relationship between total hydrocarbon (THC) exposures attributed to oil spill clean-up work and lung function 1 to 3 years after the Deepwater Horizon (DWH) disaster.Methods:We used data from the GuLF STUDY, a large cohort of adults who worked on re
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respiratory dermal and eye irritation symptoms associated with corexit ec9527a ec9500a following the Deepwater Horizon oil spill findings from the gulf study
2017Co-Authors: Craig J Mcgowan, Lawrence S Engel, Richard K Kwok, Patricia A Stewart, Mark Stenzel, Dale P SandlerAbstract:Background: The large quantities of chemical oil dispersants used in the oil spill response and cleanup (OSRC) work following the Deepwater Horizon disaster provide an opportunity to study associat...
Olivia U Mason - One of the best experts on this subject based on the ideXlab platform.
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assessment of the Deepwater Horizon oil spill impact on gulf coast microbial communities
2014Co-Authors: Regina Lamendella, Olivia U Mason, Steven C Strutt, Sharon Borglin, Romy Chakraborty, Neslihan Tas, Jenni Hultman, Emmanuel Prestat, Terry C Hazen, Janet K JanssonAbstract:One of the major environmental concerns of the Deepwater Horizon oil spill in the Gulf of Mexico was the ecological impact of the oil that reached shorelines of the Gulf Coast. Here we investigated the impact of the oil on the microbial composition in beach samples collected in June 2010 along a heavily impacted shoreline near Grand Isle, Louisiana. Successional changes in the microbial community structure due to the oil contamination were determined by deep sequencing of 16S rRNA genes. Metatranscriptomics was used to determine expression of functional genes involved in hydrocarbon degradation processes. In addition, potential hydrocarbon-degrading Bacteria were obtained in culture. The 16S data revealed that highly contaminated samples had higher abundances of Alpha- and Gammaproteobacteria sequences. Successional changes in these classes were observed over time, during which the oil was partially degraded. The metatranscriptome data revealed that PAH, n-alkane, and toluene degradation genes were expressed in the contaminated samples, with high homology to genes from Alteromonadales, Rhodobacterales, and Pseudomonales. Notably, Marinobacter (Gammaproteobacteria) had the highest representation of expressed genes in the samples. A Marinobacter isolated from this beach was shown to have potential for transformation of hydrocarbons in incubation experiments with oil obtained from the Mississippi Canyon Block 252 (MC252) well; collected during the Deepwater Horizon spill. The combined data revealed a response of the beach microbial community to oil contaminants, including prevalence of Bacteria endowed with the functional capacity to degrade oil.
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microbial gene functions enriched in the Deepwater Horizon deep sea oil plume
2012Co-Authors: Ye Deng, Joy D Van Nostrand, James W Voordeckers, Aifen Zhou, Yongjin Lee, Olivia U Mason, Eric A Dubinsky, Krystle L Chavarria, Lauren M Tom, Julian L FortneyAbstract:The Deepwater Horizon oil spill in the Gulf of Mexico is the deepest and largest offshore spill in the United State history and its impacts on marine ecosystems are largely unknown. Here, we showed that the microbial community functional composition and structure were dramatically altered in a deep-sea oil plume resulting from the spill. A variety of metabolic genes involved in both aerobic and anaerobic hydrocarbon degradation were highly enriched in the plume compared with outside the plume, indicating a great potential for intrinsic bioremediation or natural attenuation in the deep sea. Various other microbial functional genes that are relevant to carbon, nitrogen, phosphorus, sulfur and iron cycling, metal resistance and bacteriophage replication were also enriched in the plume. Together, these results suggest that the indigenous marine microbial communities could have a significant role in biodegradation of oil spills in deep-sea environments.
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deep sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill
2012Co-Authors: Olivia U Mason, Julian L Fortney, Regina Lamendella, Romy Chakraborty, Jacob Baelum, Sharon E Borglin, Manfred Auer, Marcin Zemla, Markus BillAbstract:Deep-sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill Jacob Baelum 1,2 , Sharon Borglin 1 , Romy Chakraborty 1 , Julian L. Fortney 1 , Regina Lamendella 1 , Olivia U. Mason 1 , Manfred Auer 1 , Marcin Zemla 1 , Markus Bill 1 , Mark E. Conrad 1 , Stephanie A. Malfatti 3 , Susannah G. Tringe 3 , Hoi-Ying Holman 1 , Terry C. Hazen 1 , and Janet K. Jansson 1,3* MS 70A-3317, 1 Cyclotron Rd., Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA The Geological Survey of Denmark and Greenland, Oster Voldgade 10, 1350 Copenhagen, Denmark Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA Corresponding author phone: 1-510-486-7487; e-mail: jrjansson@lbl.gov; fax: 1-510- Running title: Enrichment of oil degraders from Gulf of Mexico
Jacob Baelum - One of the best experts on this subject based on the ideXlab platform.
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deep sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill escholarship
2014Co-Authors: Jacob BaelumAbstract:Deep-sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill Jacob Baelum 1,2 , Sharon Borglin 1 , Romy Chakraborty 1 , Julian L. Fortney 1 , Regina Lamendella 1 , Olivia U. Mason 1 , Manfred Auer 1 , Marcin Zemla 1 , Markus Bill 1 , Mark E. Conrad 1 , Stephanie A. Malfatti 3 , Susannah G. Tringe 3 , Hoi-Ying Holman 1 , Terry C. Hazen 1 , and Janet K. Jansson 1,3* MS 70A-3317, 1 Cyclotron Rd., Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA The Geological Survey of Denmark and Greenland, Oster Voldgade 10, 1350 Copenhagen, Denmark Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA Corresponding author phone: 1-510-486-7487; e-mail: jrjansson@lbl.gov; fax: 1-510- Running title: Enrichment of oil degraders from Gulf of Mexico
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deep sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill
2012Co-Authors: Olivia U Mason, Julian L Fortney, Regina Lamendella, Romy Chakraborty, Jacob Baelum, Sharon E Borglin, Manfred Auer, Marcin Zemla, Markus BillAbstract:Deep-sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill Jacob Baelum 1,2 , Sharon Borglin 1 , Romy Chakraborty 1 , Julian L. Fortney 1 , Regina Lamendella 1 , Olivia U. Mason 1 , Manfred Auer 1 , Marcin Zemla 1 , Markus Bill 1 , Mark E. Conrad 1 , Stephanie A. Malfatti 3 , Susannah G. Tringe 3 , Hoi-Ying Holman 1 , Terry C. Hazen 1 , and Janet K. Jansson 1,3* MS 70A-3317, 1 Cyclotron Rd., Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA The Geological Survey of Denmark and Greenland, Oster Voldgade 10, 1350 Copenhagen, Denmark Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA Corresponding author phone: 1-510-486-7487; e-mail: jrjansson@lbl.gov; fax: 1-510- Running title: Enrichment of oil degraders from Gulf of Mexico
Terry C Hazen - One of the best experts on this subject based on the ideXlab platform.
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corrigendum the effect of hydrostatic pressure on enrichments of hydrocarbon degrading microbes from the gulf of mexico following the Deepwater Horizon oil spill
2018Co-Authors: Angeliki Marietou, Terry C Hazen, Felix Beulig, Alberto Scoma, Roger A Chastain, Douglas H. BartlettAbstract:The Deepwater Horizon oil spill was one of the largest and deepest oil spills recorded. The wellhead was located at approximately 1500 m below the sea where low temperature and high pressure are key environmental characteristics. Using cells collected 4 months following the Deepwater Horizon oil spill at the Gulf of Mexico, we set up Macondo crude oil enrichments at wellhead temperature and different pressures to determine the effect of increasing depth/pressure to the in situ microbial community and their ability to degrade oil. We observed oil degradation under all pressure conditions tested [0.1, 15, and 30 megapascals (MPa)], although oil degradation profiles, cell numbers, and hydrocarbon degradation gene abundances indicated greatest activity at atmospheric pressure. Under all incubations the growth of psychrophilic bacteria was promoted. Bacteria closely related to Oleispira antarctica RB-8 dominated the communities at all pressures. At 30 MPa we observed a shift toward Photobacterium, a genus that includes piezophiles. Alphaproteobacterial members of the Sulfitobacter, previously associated with oil-degradation, were also highly abundant at 0.1 MPa. Our results suggest that pressure acts synergistically with low temperature to slow microbial growth and thus oil degradation in deep-sea environments.
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The Effect of Hydrostatic Pressure on Enrichments of Hydrocarbon Degrading Microbes From the Gulf of Mexico Following the Deepwater Horizon Oil Spill
2018Co-Authors: Terry C Hazen, Angeliki Marietou, Roger Chastain, Felix Beulig, Alberto ScomaAbstract:The Deepwater Horizon oil spill was one of the largest and deepest oil spills recorded. The wellhead was located at approximately 1500 m below the sea where low temperature and high pressure are key environmental characteristics. Using cells collected 4 months following the Deepwater Horizon oil spill at the Gulf of Mexico, we set up Macondo crude oil enrichments at wellhead temperature and different pressures to determine the effect of increasing depth/pressure to the in situ microbial community and their ability to degrade oil. We observed oil degradation under all pressure conditions tested [0.1, 15, and 30 megapascals (MPa)], although oil degradation profiles, cell numbers, and hydrocarbon degradation gene abundances indicated greatest activity at atmospheric pressure. Under all incubations the growth of psychrophilic bacteria was promoted. Bacteria closely related to Oleispira antarctica RB-8 dominated the communities at all pressures. At 30 MPa we observed a shift toward Photobacterium, a genus that includes piezophiles. Alphaproteobacterial members of the Sulfitobacter, previously associated with oil-degradation, were also highly abundant at 0.1 MPa. Our results suggest that pressure acts synergistically with low temperature to slow microbial growth and thus oil degradation in deep-sea environments
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Image_2_The Effect of Hydrostatic Pressure on Enrichments of Hydrocarbon Degrading Microbes From the Gulf of Mexico Following the Deepwater Horizon Oil Spill.TIF
2018Co-Authors: Angeliki Marietou, Terry C Hazen, Roger Chastain, Felix Beulig, Alberto Scoma, Douglas H. BartlettAbstract:The Deepwater Horizon oil spill was one of the largest and deepest oil spills recorded. The wellhead was located at approximately 1500 m below the sea where low temperature and high pressure are key environmental characteristics. Using cells collected 4 months following the Deepwater Horizon oil spill at the Gulf of Mexico, we set up Macondo crude oil enrichments at wellhead temperature and different pressures to determine the effect of increasing depth/pressure to the in situ microbial community and their ability to degrade oil. We observed oil degradation under all pressure conditions tested [0.1, 15, and 30 megapascals (MPa)], although oil degradation profiles, cell numbers, and hydrocarbon degradation gene abundances indicated greatest activity at atmospheric pressure. Under all incubations the growth of psychrophilic bacteria was promoted. Bacteria closely related to Oleispira antarctica RB-8 dominated the communities at all pressures. At 30 MPa we observed a shift toward Photobacterium, a genus that includes piezophiles. Alphaproteobacterial members of the Sulfitobacter, previously associated with oil-degradation, were also highly abundant at 0.1 MPa. Our results suggest that pressure acts synergistically with low temperature to slow microbial growth and thus oil degradation in deep-sea environments.
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assessment of the Deepwater Horizon oil spill impact on gulf coast microbial communities
2014Co-Authors: Regina Lamendella, Olivia U Mason, Steven C Strutt, Sharon Borglin, Romy Chakraborty, Neslihan Tas, Jenni Hultman, Emmanuel Prestat, Terry C Hazen, Janet K JanssonAbstract:One of the major environmental concerns of the Deepwater Horizon oil spill in the Gulf of Mexico was the ecological impact of the oil that reached shorelines of the Gulf Coast. Here we investigated the impact of the oil on the microbial composition in beach samples collected in June 2010 along a heavily impacted shoreline near Grand Isle, Louisiana. Successional changes in the microbial community structure due to the oil contamination were determined by deep sequencing of 16S rRNA genes. Metatranscriptomics was used to determine expression of functional genes involved in hydrocarbon degradation processes. In addition, potential hydrocarbon-degrading Bacteria were obtained in culture. The 16S data revealed that highly contaminated samples had higher abundances of Alpha- and Gammaproteobacteria sequences. Successional changes in these classes were observed over time, during which the oil was partially degraded. The metatranscriptome data revealed that PAH, n-alkane, and toluene degradation genes were expressed in the contaminated samples, with high homology to genes from Alteromonadales, Rhodobacterales, and Pseudomonales. Notably, Marinobacter (Gammaproteobacteria) had the highest representation of expressed genes in the samples. A Marinobacter isolated from this beach was shown to have potential for transformation of hydrocarbons in incubation experiments with oil obtained from the Mississippi Canyon Block 252 (MC252) well; collected during the Deepwater Horizon spill. The combined data revealed a response of the beach microbial community to oil contaminants, including prevalence of Bacteria endowed with the functional capacity to degrade oil.
Julian L Fortney - One of the best experts on this subject based on the ideXlab platform.
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microbial gene functions enriched in the Deepwater Horizon deep sea oil plume
2012Co-Authors: Ye Deng, Joy D Van Nostrand, James W Voordeckers, Aifen Zhou, Yongjin Lee, Olivia U Mason, Eric A Dubinsky, Krystle L Chavarria, Lauren M Tom, Julian L FortneyAbstract:The Deepwater Horizon oil spill in the Gulf of Mexico is the deepest and largest offshore spill in the United State history and its impacts on marine ecosystems are largely unknown. Here, we showed that the microbial community functional composition and structure were dramatically altered in a deep-sea oil plume resulting from the spill. A variety of metabolic genes involved in both aerobic and anaerobic hydrocarbon degradation were highly enriched in the plume compared with outside the plume, indicating a great potential for intrinsic bioremediation or natural attenuation in the deep sea. Various other microbial functional genes that are relevant to carbon, nitrogen, phosphorus, sulfur and iron cycling, metal resistance and bacteriophage replication were also enriched in the plume. Together, these results suggest that the indigenous marine microbial communities could have a significant role in biodegradation of oil spills in deep-sea environments.
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deep sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill
2012Co-Authors: Olivia U Mason, Julian L Fortney, Regina Lamendella, Romy Chakraborty, Jacob Baelum, Sharon E Borglin, Manfred Auer, Marcin Zemla, Markus BillAbstract:Deep-sea bacteria enriched by oil and dispersant from the Deepwater Horizon spill Jacob Baelum 1,2 , Sharon Borglin 1 , Romy Chakraborty 1 , Julian L. Fortney 1 , Regina Lamendella 1 , Olivia U. Mason 1 , Manfred Auer 1 , Marcin Zemla 1 , Markus Bill 1 , Mark E. Conrad 1 , Stephanie A. Malfatti 3 , Susannah G. Tringe 3 , Hoi-Ying Holman 1 , Terry C. Hazen 1 , and Janet K. Jansson 1,3* MS 70A-3317, 1 Cyclotron Rd., Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA The Geological Survey of Denmark and Greenland, Oster Voldgade 10, 1350 Copenhagen, Denmark Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA Corresponding author phone: 1-510-486-7487; e-mail: jrjansson@lbl.gov; fax: 1-510- Running title: Enrichment of oil degraders from Gulf of Mexico
