The Experts below are selected from a list of 276 Experts worldwide ranked by ideXlab platform
Erick Carreira - One of the best experts on this subject based on the ideXlab platform.
-
pd catalyzed external co free carbonylation preparation of 2 4 6 trichlorophenyl 3 4 Dihydronaphthalene 2 carboxylate
Organic Syntheses, 2020Co-Authors: Hideyuki Konishi, Tsuyoshi Ueda, Kei Manabe, Jennifer Ciesielski, Erick CarreiraAbstract:Palladium-catalyzed carbonylation of organic (pseudo)halides has received much attention because of its versatility for the synthesis of carbonyl-containing compounds. This article discusses the preparation of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate using Pd-catalyzed external-CO-free carbonylation. It also discusses the characterization data of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate. Keywords: Pd-Catalysis; 2,4,6-Trichlorophenyl formate; 2,4,6-Trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate; 3,4-Dihydronaphthalen-2-yl trifluoromethanesulfonate
-
Organic Syntheses - Pd‐Catalyzed External‐CO‐Free Carbonylation: Preparation of 2,4,6‐Trichlorophenyl 3,4‐Dihydronaphthalene‐2‐Carboxylate
Organic Syntheses, 2014Co-Authors: Hideyuki Konishi, Tsuyoshi Ueda, Kei Manabe, Jennifer Ciesielski, Erick CarreiraAbstract:Palladium-catalyzed carbonylation of organic (pseudo)halides has received much attention because of its versatility for the synthesis of carbonyl-containing compounds. This article discusses the preparation of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate using Pd-catalyzed external-CO-free carbonylation. It also discusses the characterization data of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate. Keywords: Pd-Catalysis; 2,4,6-Trichlorophenyl formate; 2,4,6-Trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate; 3,4-Dihydronaphthalen-2-yl trifluoromethanesulfonate
Luiz F. Silva - One of the best experts on this subject based on the ideXlab platform.
-
Iodine(III)-promoted ring contraction of 1,2-Dihydronaphthalenes: a diastereoselective total synthesis of (+/-)-indatraline.
Organic Letters, 2007Co-Authors: Luiz F. Silva, Fernanda A. Siqueira, Eliane C. Pedrozo, Fabiana Y. M. Vieira, Antonio C. DoriguettoAbstract:A new approach for the synthesis of (±)-indatraline, which is a 3-phenyl-1-indanamine that displays several biological activities, is described. The strategy features as the key step a diastereoselective ring contraction of a 1,2-Dihydronaphthalene promoted by PhI(OTs)OH, to construct the indan ring system. The oxidative rearrangement of other 1,2-Dihydronaphthalenes was also investigated, generalizing this method to obtain indans.
-
Thallium trinitrate-mediated ring contraction of 1,2-Dihydronaphthalenes: the effect of electron-donating and electron-withdrawing groups
Journal of the Brazilian Chemical Society, 2005Co-Authors: Luiz F. Silva, Helena M. C. Ferraz, Raquel M. F. Sousa, Andrea M. AguilarAbstract:The oxidation of a series of 1,2-Dihydronaphthalenes substituted in the aromatic ring was investigated with thallium trinitrate (TTN) in methanol or in trimethylorthoformate (TMOF) as solvent. In all cases, indans are produced, although the yield varied from excellent to poor, depending on the structure of the substrate. The presence of an electron-donating group in the substrate favors the rearrangement, whereas significant amounts of glycolic derivatives, as well as naphthalenes, were obtained in the oxidation of 1,2-Dihydronaphthalenes bearing electron-withdrawing groups, such as Br and NO2. Mechanisms for the formation of each of these products are proposed.
-
Thallium trinitrate-mediated ring contraction of 1,2-Dihydronaphthalenes: an approach to the synthesis of indans
Tetrahedron, 2001Co-Authors: Helena M. C. Ferraz, Luiz F. Silva, Tiago O. VieiraAbstract:Abstract Oxidation of 1,2-Dihydronaphthalenes with thallium trinitrate was studied. 1,2-Dihydronaphthalene, 1-methyl-1,2-Dihydronaphthalene, 6- and 8-methoxy-1,2-Dihydronaphthalenes gave rise to the respective ring contraction products in good yields, whereas the rearrangement was not observed using 4-methyl-1,2-Dihydronaphthalene and 1-n-butyl-4-methyl-1,2-Dihydronaphthalene as substrates.
Qinghai Deng - One of the best experts on this subject based on the ideXlab platform.
-
iron catalyzed trifluoromethylation of vinylcyclopropanes facile synthesis of cf3 containing Dihydronaphthalene derivatives
Organic chemistry frontiers, 2016Co-Authors: Zongrui Li, Jing Shen, Dunqi Wu, Qinghai DengAbstract:An efficient Fe(II)-catalyzed trifluoromethylation of vinylcyclopropanes was successfully developed. A series of CF3-containing Dihydronaphthalene derivatives were prepared in moderate to high yields (up to 96%) under mild reaction conditions using the Togni reagent as the CF3 source.
-
Iron-catalyzed trifluoromethylation of vinylcyclopropanes: facile synthesis of CF3–containing Dihydronaphthalene derivatives
Organic chemistry frontiers, 2016Co-Authors: Zong‐rui Li, Jing Shen, Dun‐qi Wu, Qinghai DengAbstract:An efficient Fe(II)-catalyzed trifluoromethylation of vinylcyclopropanes was successfully developed. A series of CF3-containing Dihydronaphthalene derivatives were prepared in moderate to high yields (up to 96%) under mild reaction conditions using the Togni reagent as the CF3 source.
Hideyuki Konishi - One of the best experts on this subject based on the ideXlab platform.
-
pd catalyzed external co free carbonylation preparation of 2 4 6 trichlorophenyl 3 4 Dihydronaphthalene 2 carboxylate
Organic Syntheses, 2020Co-Authors: Hideyuki Konishi, Tsuyoshi Ueda, Kei Manabe, Jennifer Ciesielski, Erick CarreiraAbstract:Palladium-catalyzed carbonylation of organic (pseudo)halides has received much attention because of its versatility for the synthesis of carbonyl-containing compounds. This article discusses the preparation of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate using Pd-catalyzed external-CO-free carbonylation. It also discusses the characterization data of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate. Keywords: Pd-Catalysis; 2,4,6-Trichlorophenyl formate; 2,4,6-Trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate; 3,4-Dihydronaphthalen-2-yl trifluoromethanesulfonate
-
Organic Syntheses - Pd‐Catalyzed External‐CO‐Free Carbonylation: Preparation of 2,4,6‐Trichlorophenyl 3,4‐Dihydronaphthalene‐2‐Carboxylate
Organic Syntheses, 2014Co-Authors: Hideyuki Konishi, Tsuyoshi Ueda, Kei Manabe, Jennifer Ciesielski, Erick CarreiraAbstract:Palladium-catalyzed carbonylation of organic (pseudo)halides has received much attention because of its versatility for the synthesis of carbonyl-containing compounds. This article discusses the preparation of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate using Pd-catalyzed external-CO-free carbonylation. It also discusses the characterization data of 2,4,6-trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate. Keywords: Pd-Catalysis; 2,4,6-Trichlorophenyl formate; 2,4,6-Trichlorophenyl 3,4-Dihydronaphthalene-2-carboxylate; 3,4-Dihydronaphthalen-2-yl trifluoromethanesulfonate
M A M Healy - One of the best experts on this subject based on the ideXlab platform.
-
preparation of 1 substituted 3 4 Dihydronaphthalene 2 carboxaldehyde n n dimethylhydrazones by palladium 0 coupling and their electrocyclic ring closure
Tetrahedron, 1993Co-Authors: Thomas L Gilchrist, M A M HealyAbstract:Abstract 1-Bromo-3,4-Dihydronaphthalene-2-carboxaldehyde 2 has been converted by three methods, each involving halogen-metal exchange and palladium(0) catalysed cross coupling, into N,N-dimethylhydrazones of 1-aryl- and 1-vinyl-3,4-Dihydronaphthalene-2- carboxaldehydes. The N,N-dimethylhydrazone 10 of the aldehyde 2 undergoes efficient bromine-lithium exchange with butyllithium, as does 2-bromobenzaldehyde N,N-dimethylhydrazone 17. The dimethylhydrazones of 1-vinyl-3,4-Dihydronaphthalene-2-carboxaldehydes were not isolated by underwent electrocyclic ring closure followed by loss of dimethylamine in solution to give 5,6-dihydrobenz[f]isoquinolines. 1-Aryl-3,4-Dihydronaphthalene-2- carboxaldehyde N,N-dimethylhydrazones also cyclised in the same way when subjected to vapour phase pyrolysis.