The Experts below are selected from a list of 155061 Experts worldwide ranked by ideXlab platform

Martin Resano - One of the best experts on this subject based on the ideXlab platform.

  • direct trace Elemental Analysis of urine samples by laser ablation inductively coupled plasma mass spectrometry after sample deposition on clinical filter papers
    2012
    Co-Authors: Maite Aramendia, Luis Rello, Frank Vanhaecke, Martin Resano
    Abstract:

    Collection of biological fluids on clinical filter papers shows important advantages from a logistic point of view, although Analysis of these specimens is far from straightforward. Concerning urine Analysis, and particularly when direct trace Elemental Analysis by laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS) is aimed at, several problems arise, such as lack of sensitivity or different distribution of the analytes on the filter paper, rendering obtaining reliable quantitative results quite difficult. In this paper, a novel approach for urine collection is proposed, which circumvents many of these problems. This methodology consists on the use of precut filter paper discs where large amounts of sample can be retained upon a single deposition. This provides higher amounts of the target analytes and, thus, sufficient sensitivity, and allows addition of an adequate internal standard at the clinical lab prior to Analysis, therefore making it suitable for a strategy based on unsupervis...

Ralf Matschat - One of the best experts on this subject based on the ideXlab platform.

Jose R Almirall - One of the best experts on this subject based on the ideXlab platform.

  • Elemental Analysis of glass by laser ablation inductively coupled plasma optical emission spectrometry la icp oes
    2012
    Co-Authors: Emily R Schenk, Jose R Almirall
    Abstract:

    The Elemental Analysis of glass evidence has been established as a powerful discrimination tool for forensic analysts. Laser ablation inductively coupled plasma optical emission spectrometry (LA-ICP-OES) has been compared to laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and energy dispersive micro X-ray fluorescence spectroscopy (μXRF/EDS) as competing instrumentation for the Elemental Analysis of glass. The development of a method for the forensic Analysis of glass coupling laser ablation to ICP-OES is presented for the first time. LA-ICP-OES has demonstrated comparable analytical performance to LA-ICP-MS based on the use of the element menu, Al (Al I 396.15 nm), Ba (Ba II 455.40 nm), Ca (Ca II 315.88 nm), Fe (Fe II 238.20 nm), Li (Li I 670.78 nm), Mg (Mg I 285.21 nm), Sr (Sr II 407.77 nm), Ti (Ti II 368.51 nm), and Zr (Zr II 343.82 nm). The relevant figures of merit, such as precision, accuracy and sensitivity, are presented and compared to LA-ICP-MS. A set of 41 glass samples was used to assess the discrimination power of the LA-ICP-OES method in comparison to other Elemental Analysis techniques. This sample set consisted of several vehicle glass samples that originated from the same source (inside and outside windshield panes) and several glass samples that originated from different vehicles. Different match criteria were used and compared to determine the potential for Type I and Type II errors. It was determined that broader match criteria is more applicable to the forensic comparison of glass Analysis because it can reduce the affect that micro-heterogeneity inherent in the glass fragments and a less than ideal sampling strategy can have on the interpretation of the results. Based on the test set reported here, a plus or minus four standard deviation (± 4s) match criterion yielded the lowest possibility of Type I and Type II errors. The developed LA-ICP-OES method has been shown to perform similarly to LA-ICP-MS in the discrimination among different sources of glass while offering the advantages of a lower cost of acquisition and operation of analytical instrumentation making ICP-OES a possible alternative Elemental Analysis method for the forensic laboratory.

Jan K Schjoerring - One of the best experts on this subject based on the ideXlab platform.

  • micro scaled high throughput digestion of plant tissue samples for multi Elemental Analysis
    2009
    Co-Authors: Thomas H Hansen, Kristian Holst Laursen, Daniel P Persson, Pai Pedas, Soren Husted, Jan K Schjoerring
    Abstract:

    Background Quantitative multi-Elemental Analysis by inductively coupled plasma (ICP) spectrometry depends on a complete digestion of solid samples. However, fast and thorough sample digestion is a challenging analytical task which constitutes a bottleneck in modern multi-Elemental Analysis. Additional obstacles may be that sample quantities are limited and Elemental concentrations low. In such cases, digestion in small volumes with minimum dilution and contamination is required in order to obtain high accuracy data.

  • micro scaled high throughput digestion of plant tissue samples for multi Elemental Analysis
    2009
    Co-Authors: Thomas H Hansen, Kristian Holst Laursen, Daniel P Persson, Pai Pedas, Soren Husted, Jan K Schjoerring
    Abstract:

    Quantitative multi-Elemental Analysis by inductively coupled plasma (ICP) spectrometry depends on a complete digestion of solid samples. However, fast and thorough sample digestion is a challenging analytical task which constitutes a bottleneck in modern multi-Elemental Analysis. Additional obstacles may be that sample quantities are limited and Elemental concentrations low. In such cases, digestion in small volumes with minimum dilution and contamination is required in order to obtain high accuracy data. We have developed a micro-scaled microwave digestion procedure and optimized it for accurate Elemental profiling of plant materials (1-20 mg dry weight). A commercially available 64-position rotor with 5 ml disposable glass vials, originally designed for microwave-based parallel organic synthesis, was used as a platform for the digestion. The novel micro-scaled method was successfully validated by the use of various certified reference materials (CRM) with matrices rich in starch, lipid or protein. When the micro-scaled digestion procedure was applied on single rice grains or small batches of Arabidopsis seeds (1 mg, corresponding to approximately 50 seeds), the obtained Elemental profiles closely matched those obtained by conventional Analysis using digestion in large volume vessels. Accumulated Elemental contents derived from separate analyses of rice grain fractions (aleurone, embryo and endosperm) closely matched the total content obtained by Analysis of the whole rice grain. A high-throughput micro-scaled method has been developed which enables digestion of small quantities of plant samples for subsequent Elemental profiling by ICP-spectrometry. The method constitutes a valuable tool for screening of mutants and transformants. In addition, the method facilitates studies of the distribution of essential trace elements between and within plant organs which is relevant for, e.g., breeding programmes aiming at improvement of the micronutrient density in edible plant parts. Compared to existing vial-in-vial systems, the new method developed here represents a significant methodological advancement in terms of higher capacity, reduced labour consumption, lower material costs, less contamination and, as a consequence, improved analytical accuracy following micro-scaled digestion of plant samples.

Heinrich Kipphardt - One of the best experts on this subject based on the ideXlab platform.