The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Alessandro Grecucci - One of the best experts on this subject based on the ideXlab platform.
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schema therapy for Emotional Dysregulation in personality disorders a review
Current Opinion in Psychiatry, 2018Co-Authors: Harold Dadomo, Alessandro Carmelita, Marta Panzeri, Daniele Caponcello, Alessandro GrecucciAbstract:Purpose of reviewTo give an update on the most recent studies regarding the role of schema therapy in the treatment of emotion Dysregulation related to personality disorders.Recent findingsIn personality disorders, a lack of emotion regulation can be found. Schema therapy treats emotion dysregulatio
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schema therapy for Emotional Dysregulation theoretical implication and clinical applications
Frontiers in Psychology, 2016Co-Authors: Harold Dadomo, Alessandro Grecucci, Irene Giardini, Erika Ugolini, Alessandro Carmelita, Marta PanzeriAbstract:The term Emotional Dysregulation refers to an impaired ability to regulate unwanted Emotional states. Scientific evidence supports the idea that Emotional Dysregulation underlies several psychological disorders as, for example: personality disorders, bipolar disorder type II, interpersonal trauma, anxiety disorders, mood disorders and post-traumatic stress disorder. Emotional Dysregulation may derive from early interpersonal traumas in childhood. These early traumatic events create a persistent sensitization of the central nervous system in relation to early life stressing events. For this reason, some authors suggest a common endophenotypical origin across psychopathologies. In the last 20 years, cognitive behavioral therapy has increasingly adopted an interactive-ontogenetic view to explain the development of disorders associated to Emotional Dysregulation. Unfortunately, standard Cognitive Behavior Therapy (CBT) methods are not useful in treating Emotional Dysregulation. A CBT-derived new approach called Schema Therapy (ST), that integrates theory and techniques from psychodynamic and emotion focused therapy, holds the promise to fill this gap in cognitive literature. In this model, psychopathology is viewed as the interaction between the innate temperament of the child and the early experiences of deprivation or frustration of the subject’s basic needs. This deprivation may lead to develop early maladaptive schemas (EMS), and maladaptive Modes. In the present paper we point out that EMSs and Modes are associated with either dysregulated emotions or with dysregulatory strategies that produce and maintain problematic Emotional responses. Thanks to a special focus on the therapeutic relationship and emotion focused-experiential techniques, this approach successfully treats severe Emotional Dysregulation. In this paper, we make several comparisons between the main ideas of ST and the science of emotion regulation, and we present how to conceptualize pathological phenomena in terms of failed regulation and some of the ST strategies and techniques to foster successful regulation in patients.
Gabriele Masi - One of the best experts on this subject based on the ideXlab platform.
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an exploratory study of Emotional Dysregulation dimensions in youth with attention deficit hyperactivity disorder and or bipolar spectrum disorders
Frontiers in Psychiatry, 2021Co-Authors: Gabriele Masi, Gianluca Sesso, Chiara Pfanner, Elena Valente, Agnese Molesti, Francesca Placini, Silvia Boldrini, Nina Loriaux, Flavia Drago, Anna Rita MontesantoAbstract:Emotional Dysregulation (ED) is currently the most frequently used term to describe children with an impaired regulation of Emotional states. Recent research studies speculate whether ED may be a neurodevelopmental disorder itself, a shared risk factor, or a common key feature of several psychiatric disorders, including, among others, attention deficit hyperactivity disorder (ADHD), and bipolar spectrum disorders (BSD). The association between ADHD and ED is one of the main reasons of misconceptions in the definition of boundaries between ADHD and BSD, leading to the frequent misdiagnosis of ADHD as BSD. Since ED is a multidimensional concept, a novel instrument-the Reactivity, Intensity, Polarity and Stability (RIPoSt) scale-was recently developed to assess the different dimensions of ED, which could help in detecting specific ED profiles in clinical youths. Our study included 154 patients, aged 13.8 ± 2.3 years, diagnosed with either ADHD, BSD, or comorbid condition, and a school-based sample of 40 healthy control (HC) adolescents, aged 12.5 ± 1.2 years. The RIPoSt scale and the Child Behavior Checklist were administered to both groups. Our results indicate that affective instability and negative Emotionality subscales, as well as negative Emotional Dysregulation, are higher in BSD, both pure and comorbid with ADHD, while Emotional impulsivity is higher in the comorbid condition and similar in the ADHD and BSD alone group; all clinical groups scored higher than HC. Conversely, positive Emotionality is similar among clinical groups and within them and HC. Our findings also support the validity of the RIPoSt questionnaire, since the instrument proved to have good-to-excellent internal consistency, and strongly significant positive correlations were found with the CBCL-Dysregulation Profile, which is a commonly used, indirect measure of ED. Hence, the five subscales of the RIPoSt can be reliably used as an effective tool to study the Emotional Dysregulation in different clinical conditions, to help disentangle the complex relationship between ADHD and juvenile BSD and to provide clinicians with crucial evidence for better diagnostic characterization and therapeutic indications.
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Emotional Dysregulation and callous unEmotional traits as possible predictors of short term response to methylphenidate monotherapy in drug naive youth with adhd
Comprehensive Psychiatry, 2020Co-Authors: Gabriele Masi, Chiara Pfanner, Pamela Fantozzi, Pietro Muratori, Giulia Bertolucci, Annalisa Tacchi, Arianna Villafranca, Samuele CorteseAbstract:Abstract Background Emotional Dysregulation (ED) and callous unEmotional (CU) traits can be associated with ADHD in youth, influencing its natural history and outcome, but their effect on medication efficacy is unexplored. We examined whether two measures of baseline ED and CU traits, the Child Behavior Checklist-Dysregulation Profile (CBCL-DP) and the Antisocial Process Screening Device (APSD), respectively, were predictors of change of ADHD-Rating Scale (ADHD-RS) after a 4-week methylphenidate (MPH) monotherapy. Methods 43 patients (37 males, 8–16 years, mean 9.9 ± 2.7 years) were included. Hierarchical linear regression models were used to explore whether CBCL-DP and APSD might predict ADHD-RS score, controlling for baseline severity. Results Baseline CBCL-DP predicted higher post-treatment ADHD-RS scores in total and hyperactivity-impulsivity, but not in inattention subscale. Baseline APSD was not significantly related to ADHD-RS scores at the follow-up. Limitations Small sample size, lack of gender diversity, non-blind design and short period of observation. Conclusion ED, assessed with that CBCL-DP, might be a negative predictor of change of hyperactive-impulsive symptoms after MPH treatment and should be systematically assessed at baseline.
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pharmacotherapy of Emotional Dysregulation in adults with adhd a systematic review and meta analysis
Neuroscience & Biobehavioral Reviews, 2018Co-Authors: Francesca Lenzi, Samuele Cortese, Joseph Harris, Gabriele MasiAbstract:Abstract Emotional Dysregulation (ED) is a dysfunction in modifying an Emotional state in an adaptive and goal oriented way, with excitability, ease anger, and mood lability. It is present in up to 70% of adults with ADHD, regardless of other comorbidities, and substantially worsens the psychosocial outcomes of the disorder. Besides fronto-parietal circuits mediating top-down control, brain regions involved in bottom-up processes (e.g., amygdala, orbitofrontal cortex, and ventral striatum) are implicated in ED. We performed a systematic review/meta-analysis of double-blind randomized controlled trials of ADHD medications to assess their effects on ED in adults with ADHD. We searched an extensive set of databases, international trials registries, and contacted study authors/drug companies for unpublished data. We retained 21 trials. We found small-to-moderate effects (methylphenidate: SMD = 0.34, 95% CI = 0.23–0.45; atomoxetine: SMD = 0.24, 95% CI = 0.15–0.34; lisdexamfetamine: SMD = 0.50, 95% CI = 0.21–0.8). We suggest that, whilst ADHD medications are effective on ADHD core symptoms, they may be less effective on bottom-up mechanisms underlying ED. Further research on novel pharmacological and non-pharmacological strategies for ED in adults with ADHD is warranted. PROSPERO: CRD42017068426.
Stephen V Faraone - One of the best experts on this subject based on the ideXlab platform.
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evaluating chronic Emotional Dysregulation and irritability in relation to adhd and depression genetic risk in children with adhd
Journal of Child Psychology and Psychiatry, 2020Co-Authors: Joel T Nigg, Stephen V Faraone, Sarah L Karalunas, Hanna C Gustafsson, Priya Bhatt, Peter Ryabinin, Michael Mooney, Damien A Fair, Beth WilmotAbstract:BACKGROUND A central nosological problem concerns the etiological relationship of Emotional Dysregulation with ADHD. Molecular genetic risk scores provide a novel method for informing this question. METHODS Participants were 514 community-recruited children of Northern European descent age 7-11 defined as ADHD or non-ADHD by detailed research evaluation. Parents-rated ADHD on standardized ratings and child temperament on the Temperament in Middle Childhood Questionnaire (TMCQ) and reported on ADHD and comorbid disorders by semi-structured clinical interview. Categorical and dimensional variables were created for ADHD, Emotional Dysregulation (implicating disruption of regulation of both anger-irritability and of positive valence surgency-sensation seeking), and irritability alone (anger Dysregulation). Genome-wide polygenic risk scores (PRS) were computed for ADHD and depression genetic liability. Structural equation models and computationally derived emotion profiles guided analysis. RESULTS The ADHD PRS was associated in variable-centered analyses with irritability (β = .179, 95% CI = 0.087-0.280; ΔR2 = .034, p < .0002), but also with surgency/sensation seeking (B = .146, 95%CI = 0.052-0.240, ΔR2 =.022, p = .002). In person-centered analysis, the ADHD PRS was elevated in the emotion Dysregulation ADHD group versus other ADHD children (OR = 1.44, 95% CI = 1.03-2.20, Nagelkerke ΔR2 = .013, p = .033) but did not differentiate irritable from surgent ADHD profiles. All effects were independent of variation in ADHD severity across traits or groups. The depression PRS was related to oppositional defiant disorder but not to ADHD emotion Dysregulation. CONCLUSIONS Irritability-anger and surgency-sensation seeking, as forms of negative and positively valenced dysregulated affect in ADHD populations, both relate principally to ADHD genetic risk and not mood-related genetic risk.
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practitioner review Emotional Dysregulation in attention deficit hyperactivity disorder implications for clinical recognition and intervention
Journal of Child Psychology and Psychiatry, 2019Co-Authors: Stephen V Faraone, Anthony L Rostain, Joseph C Blader, Betsy Busch, Ann C Childress, Daniel F Connor, Jeffrey H NewcornAbstract:BACKGROUND Because Emotional symptoms are common in attention-deficit/hyperactivity disorder (ADHD) patients and associate with much morbidity, some consider it to be a core feature rather than an associated trait. Others argue that Emotional symptoms are too nonspecific for use as diagnostic criteria. This debate has been difficult to resolve due, in part, to the many terms used to describe Emotional symptoms in ADHD and to concerns about overlap with mood disorders. METHODS We sought to clarify the nature of Emotional symptoms in ADHD by reviewing conceptual and measurement issues and by examining the evidence base regarding specificity of such symptoms for ADHD. We reviewed the various terms used to define Emotional symptoms in ADHD, clarify how these symptoms are demarcated from mood disorders, and assess the possibility that symptoms of Emotional impulsivity and deficient Emotional self-regulation should be considered as core symptoms. We addressed psychiatric comorbidities, the effects of ADHD treatments on associated Emotional Dysregulation, and the utility of current rating scales to assess Emotional symptoms associated with ADHD. RESULTS Emotional symptoms are common and persistent in youth and adults with ADHD. Although Emotional symptoms are common in other psychiatric disorders, Emotional impulsivity (EI), and deficient Emotional self-regulation (DESR) may be sufficiently specific for ADHD to function as diagnostic criteria. CONCLUSIONS Emotional symptoms in ADHD cause clinically significant impairments. Although there is a solid theoretical rationale for considering EI and DESR to be core symptoms of ADHD, there is no consensus about how to define these constructs sin a manner that would be specific to the disorder. An instrument to measure EI and DESR which demarcates them from irritability and other Emotional symptoms could improve the accuracy of diagnostic criteria for ADHD.
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a familial risk analysis of Emotional Dysregulation a controlled study
Journal of Attention Disorders, 2018Co-Authors: Joseph Biederman, Thomas J Spencer, James Chan, Stephen V Faraone, Yvonne K Woodworth, Janet WozniakAbstract:Objective: Children with deficits in Emotional regulation operationalized by scores on the Child Behavior Checklist (CBCL) Attention Problems, Aggressive Behavior, and Anxious-Depressed subscales are more likely than others to manifest adverse outcomes. However, the transmission of this profile has not been well studied. The main aim of this study was to investigate the familiality of this profile. Method: Participants were youth probands with bipolar I (BP-I) disorder (N = 140), ADHD (N = 83), and controls (N = 117) and their siblings. Based on the CBCL Emotional Dysregulation profile, we classified children with severe Emotional Dysregulation (aggregate cut-off score ≥210) and Emotional Dysregulation (aggregate cut-off score ≥ 180 and <210). Results: Emotional Dysregulation profile scores correlated positively between probands and siblings. Conclusion: Youth with Emotional Dysregulation are at increased risk to have siblings with similar deficits, suggesting that Emotional Dysregulation runs in families.
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high risk for severe Emotional Dysregulation in psychiatrically referred youth with autism spectrum disorder a controlled study
Journal of Autism and Developmental Disorders, 2018Co-Authors: Gagan Joshi, Stephen V Faraone, Janet Wozniak, Maura Fitzgerald, Ronna Fried, Maribel Galdo, Stephannie L Furtak, Kristina Conroy, Ryan J KilcullenAbstract:To assess prevalence and severity of Emotional Dysregulation (ED) in psychiatrically referred youth with autism spectrum disorder (ASD). ASD youth (N = 123) were compared to youth with attention-deficit/hyperactivity disorder (ADHD) and controls. The majority of psychiatrically referred youth with ASD had positive Child Behavior Checklist-ED (CBCL-ED) profile that was significantly higher than in youth with ADHD (82 vs. 53%; p < 0.001). The severe Emotional Dysregulation (SED) profile was significantly greater in ASD youth than ADHD (44 vs. 15%; p < 0.001). In the presence of SED profile ASD youth suffered from greater severity of autism, associated psychopathology, and psychosocial dysfunction. Greater than expected prevalence of SED in psychiatrically referred youth with ASD that identifies distinct clinical correlates associated with severe morbidity and dysfunction.
Harold Dadomo - One of the best experts on this subject based on the ideXlab platform.
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schema therapy for Emotional Dysregulation in personality disorders a review
Current Opinion in Psychiatry, 2018Co-Authors: Harold Dadomo, Alessandro Carmelita, Marta Panzeri, Daniele Caponcello, Alessandro GrecucciAbstract:Purpose of reviewTo give an update on the most recent studies regarding the role of schema therapy in the treatment of emotion Dysregulation related to personality disorders.Recent findingsIn personality disorders, a lack of emotion regulation can be found. Schema therapy treats emotion dysregulatio
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schema therapy for Emotional Dysregulation theoretical implication and clinical applications
Frontiers in Psychology, 2016Co-Authors: Harold Dadomo, Alessandro Grecucci, Irene Giardini, Erika Ugolini, Alessandro Carmelita, Marta PanzeriAbstract:The term Emotional Dysregulation refers to an impaired ability to regulate unwanted Emotional states. Scientific evidence supports the idea that Emotional Dysregulation underlies several psychological disorders as, for example: personality disorders, bipolar disorder type II, interpersonal trauma, anxiety disorders, mood disorders and post-traumatic stress disorder. Emotional Dysregulation may derive from early interpersonal traumas in childhood. These early traumatic events create a persistent sensitization of the central nervous system in relation to early life stressing events. For this reason, some authors suggest a common endophenotypical origin across psychopathologies. In the last 20 years, cognitive behavioral therapy has increasingly adopted an interactive-ontogenetic view to explain the development of disorders associated to Emotional Dysregulation. Unfortunately, standard Cognitive Behavior Therapy (CBT) methods are not useful in treating Emotional Dysregulation. A CBT-derived new approach called Schema Therapy (ST), that integrates theory and techniques from psychodynamic and emotion focused therapy, holds the promise to fill this gap in cognitive literature. In this model, psychopathology is viewed as the interaction between the innate temperament of the child and the early experiences of deprivation or frustration of the subject’s basic needs. This deprivation may lead to develop early maladaptive schemas (EMS), and maladaptive Modes. In the present paper we point out that EMSs and Modes are associated with either dysregulated emotions or with dysregulatory strategies that produce and maintain problematic Emotional responses. Thanks to a special focus on the therapeutic relationship and emotion focused-experiential techniques, this approach successfully treats severe Emotional Dysregulation. In this paper, we make several comparisons between the main ideas of ST and the science of emotion regulation, and we present how to conceptualize pathological phenomena in terms of failed regulation and some of the ST strategies and techniques to foster successful regulation in patients.
Marta Panzeri - One of the best experts on this subject based on the ideXlab platform.
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schema therapy for Emotional Dysregulation in personality disorders a review
Current Opinion in Psychiatry, 2018Co-Authors: Harold Dadomo, Alessandro Carmelita, Marta Panzeri, Daniele Caponcello, Alessandro GrecucciAbstract:Purpose of reviewTo give an update on the most recent studies regarding the role of schema therapy in the treatment of emotion Dysregulation related to personality disorders.Recent findingsIn personality disorders, a lack of emotion regulation can be found. Schema therapy treats emotion dysregulatio
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schema therapy for Emotional Dysregulation theoretical implication and clinical applications
Frontiers in Psychology, 2016Co-Authors: Harold Dadomo, Alessandro Grecucci, Irene Giardini, Erika Ugolini, Alessandro Carmelita, Marta PanzeriAbstract:The term Emotional Dysregulation refers to an impaired ability to regulate unwanted Emotional states. Scientific evidence supports the idea that Emotional Dysregulation underlies several psychological disorders as, for example: personality disorders, bipolar disorder type II, interpersonal trauma, anxiety disorders, mood disorders and post-traumatic stress disorder. Emotional Dysregulation may derive from early interpersonal traumas in childhood. These early traumatic events create a persistent sensitization of the central nervous system in relation to early life stressing events. For this reason, some authors suggest a common endophenotypical origin across psychopathologies. In the last 20 years, cognitive behavioral therapy has increasingly adopted an interactive-ontogenetic view to explain the development of disorders associated to Emotional Dysregulation. Unfortunately, standard Cognitive Behavior Therapy (CBT) methods are not useful in treating Emotional Dysregulation. A CBT-derived new approach called Schema Therapy (ST), that integrates theory and techniques from psychodynamic and emotion focused therapy, holds the promise to fill this gap in cognitive literature. In this model, psychopathology is viewed as the interaction between the innate temperament of the child and the early experiences of deprivation or frustration of the subject’s basic needs. This deprivation may lead to develop early maladaptive schemas (EMS), and maladaptive Modes. In the present paper we point out that EMSs and Modes are associated with either dysregulated emotions or with dysregulatory strategies that produce and maintain problematic Emotional responses. Thanks to a special focus on the therapeutic relationship and emotion focused-experiential techniques, this approach successfully treats severe Emotional Dysregulation. In this paper, we make several comparisons between the main ideas of ST and the science of emotion regulation, and we present how to conceptualize pathological phenomena in terms of failed regulation and some of the ST strategies and techniques to foster successful regulation in patients.