The Experts below are selected from a list of 63675 Experts worldwide ranked by ideXlab platform
Leonard J Abbeduto - One of the best experts on this subject based on the ideXlab platform.
-
Expressive Language development in adolescents with down syndrome and fragile x syndrome change over time and the role of family related factors
Journal of Neurodevelopmental Disorders, 2020Co-Authors: Laura Del Hoyo Soriano, Sara T Kover, Angela John Thurman, Danielle J Harvey, Leonard J AbbedutoAbstract:It is well known that individuals with Down syndrome (DS) or fragile X syndrome (FXS) demonstrate Expressive Language difficulties beginning early in childhood. It is less clear, however, whether Expressive Language skills change during the adolescent period in these individuals, and if any of these changes are syndrome specific. Studying this, as well as the role of maternal and family-related factors in Expressive Language development, may provide the foundation for efficacious interventions for adolescents with DS or FXS. In this study, we examined Expressive Language trajectories, assessed through conversation and narration, in 57 adolescent males with intellectual disability (ID) (20 DS and 37 FXS) in relation to the diagnostic group (DS vs. FXS) and family-related factors (maternal IQ, maternal psychological distress, closeness in the mother–child relationship, family income, and maternal and paternal education) after adjusting for chronological age (CA) and nonverbal cognition. Changes over repeated annual assessments for males with DS or FXS were observed only during conversation, such as an increase in talkativeness, but a decrease in syntax complexity and lexical diversity. We found a diagnosis-related effect in the change over time in conversational talkativeness favoring those with FXS. Finally, a closer mother–child relationship predicted less decrease over time in lexical diversity during conversation, and participants of mothers who graduated college showed a greater increase in conversational talkativeness over time compared to those of mothers with a high school education. Our results suggest that, during the adolescent period for males with DS or FXS, there is an increase in the amount of talk produced in conversational contexts, but also a decrease in the quality of the Language produced. In addition, our results indicate syndrome-specificity for aspects of Expressive Language development and reinforce the protective role of family-related factors.
-
development of an Expressive Language sampling procedure in fragile x syndrome a pilot study
Journal of Developmental and Behavioral Pediatrics, 2013Co-Authors: Elizabeth Berrykravis, Emily Doll, Audra Sterling, Sara T Kover, Susen Schroeder, Shaguna Mathur, Leonard J AbbedutoAbstract:There is a great need for valid outcome measures of functional improvement for impending clinical trials of targeted interventions for fragile X syndrome (FXS). Families often report conversational Language improvement during clinical treatment, but no validated measures exist to quantify this outcome. This small-scale study sought to determine the feasibility, reproducibility, and clinical validity of highly structured Expressive Language sampling as an outcome measure reflecting Language ability.Narrative and conversation tasks were administered to 36 verbal participants (25 males and 11 females) with FXS (aged 5-36 years, mean, 18 ± 7 years). Alternate versions were used with randomized task order at 2- to 3-week intervals (mean, 19.6 ± 6.4 days). Audio recordings of sessions were transcribed and analyzed. Dependent measures reflected talkativeness (total number of utterances), utterance planning (proportion of communication [C] units with mazes), articulation (proportion of unintelligible/partly unintelligible C-units), vocabulary (number of different word roots), and syntactic ability (mean length of utterance [MLU] in words). Reproducibility of measures was evaluated with intraclass correlation coefficients (ICC).All participants could complete the tasks. Coded data were highly reproducible with Pearson's correlations at p < .01 for all measures and ICC values of .911 to .966 (conversation) and .728 to .940 (narration). Some measures including MLU and different word roots were correlated with Expressive Language subscale scores from the Vineland Adaptive Behavior Scale.These Expressive Language sampling tasks appear to be feasible, reproducible, and clinically valid and should be further validated in a larger cohort, as a promising means of assessing functional Expressive Language outcomes during clinical trials in FXS.
-
Development of an Expressive Language sampling procedure in fragile X syndrome: a pilot study.
Journal of developmental and behavioral pediatrics : JDBP, 2013Co-Authors: Elizabeth Berry-kravis, Emily Doll, Audra Sterling, Sara T Kover, Susen Schroeder, Shaguna Mathur, Leonard J AbbedutoAbstract:OBJECTIVE There is a great need for valid outcome measures of functional improvement for impending clinical trials of targeted interventions for fragile X syndrome (FXS). Families often report conversational Language improvement during clinical treatment, but no validated measures exist to quantify this outcome. This small-scale study sought to determine the feasibility, reproducibility, and clinical validity of highly structured Expressive Language sampling as an outcome measure reflecting Language ability. METHODS Narrative and conversation tasks were administered to 36 verbal participants (25 males and 11 females) with FXS (aged 5-36 years, mean, 18 ± 7 years). Alternate versions were used with randomized task order at 2- to 3-week intervals (mean, 19.6 ± 6.4 days). Audio recordings of sessions were transcribed and analyzed. Dependent measures reflected talkativeness (total number of utterances), utterance planning (proportion of communication [C] units with mazes), articulation (proportion of unintelligible/partly unintelligible C-units), vocabulary (number of different word roots), and syntactic ability (mean length of utterance [MLU] in words). Reproducibility of measures was evaluated with intraclass correlation coefficients (ICC). RESULTS All participants could complete the tasks. Coded data were highly reproducible with Pearson's correlations at p < .01 for all measures and ICC values of .911 to .966 (conversation) and .728 to .940 (narration). Some measures including MLU and different word roots were correlated with Expressive Language subscale scores from the Vineland Adaptive Behavior Scale. CONCLUSIONS These Expressive Language sampling tasks appear to be feasible, reproducible, and clinically valid and should be further validated in a larger cohort, as a promising means of assessing functional Expressive Language outcomes during clinical trials in FXS.
-
Effects of Sampling Context on Spontaneous Expressive Language in Males With Fragile X Syndrome or Down Syndrome
Journal of speech language and hearing research : JSLHR, 2012Co-Authors: Sara T Kover, Leonard J Abbeduto, Andrea Mcduffie, W. Ted BrownAbstract:Purpose In this study, the authors examined the impact of sampling context on multiple aspects of Expressive Language in male participants with fragile X syndrome in comparison to male participants...
-
Expressive Language in male adolescents with fragile x syndrome with and without comorbid autism
Journal of Intellectual Disability Research, 2010Co-Authors: Sara T Kover, Leonard J AbbedutoAbstract:Background Approximately one-quarter of indi- viduals with fragile X syndrome (FXS) meet diag- nostic criteria for autism; however, it is unclear whether individuals with comorbid FXS and autism are simply more severely affected than their peers with only FXS or whether they have qualitatively different profiles of behavioural impairments.To address this issue, variation in the FXS linguistic phenotype was examined in males with FXS with and without autism.The syndrome-specificity of the Expressive Language impairment of both groups of those with FXS was assessed in relation to Down syndrome.The extent to which different Language sampling contexts affected Expressive Language in each diagnostic group was also examined. Method Spontaneous Language samples were col- lected from male adolescents with FXS without autism (n = 20), comorbid FXS and autism (n = 8), and Down syndrome (n = 16). Syntactic complexity (indexed by mean length of utterance), Expressive vocabulary (indexed by lexical diversity), talkative- ness, fluency and intelligibility were assessed in two contexts: conversation and narration. Groups were matched on non-verbal IQ, non-verbal mental age and chronological age to allow the assessment of relative strengths and weaknesses across Language variables. Results Males with comorbid FXS and autism were less intelligible than males with only FXS; no other differences between these two groups were found. Participants' performance differed across contexts for syntactic complexity, lexical diversity, talkativeness and fluency. Conclusions These findings contribute to existing research on the behavioural profiles of individuals with FXS or FXS with autism who have low cogni- tive abilities. Although individuals with comorbid FXS and autism may be, as a group, more impaired than those with only FXS, data from this small sample of males with comorbid FXS and autism with low IQs suggest that their relative strengths and weaknesses in spontaneous Expressive Language are largely comparable and not differentially affected by the context in which their talk occurs.
Richard E. Tremblay - One of the best experts on this subject based on the ideXlab platform.
-
Expressive Language and prosocial behaviour in early childhood longitudinal associations in the uk millennium cohort study
European Journal of Developmental Psychology, 2017Co-Authors: Lisa-christine Girard, Jean-baptiste Pingault, Orla Doyle, Bruno Falissard, Richard E. TremblayAbstract:AbstractBackground: Early childhood is a crucial period for Language development and building social skills. While distinct, these two processes may impact upon each other.Aims: The current study aimed to identify the directional associations between Expressive Language ability and prosocial behaviour between three and five years of age.Methods: Participants included 14, 004 children and their families enrolled in the UK Millennium Cohort Study. Children’s Expressive Language and prosocial behaviour were assessed at three and five years of age utilizing standardized assessments and parent reports. Cross-lagged models were used for data analysis.Results: Better Expressive Language at three years was associated with increased prosocial behaviour by five years. No support for the inverse direction of association was found.Conclusions: Children’s early ability to effectively express themselves with others may help in building better social relationships by entry into formal schooling. Programming efforts that...
-
Developmental Associations Between Conduct Problems and Expressive Language in Early Childhood: A Population-Based Study
Journal of Abnormal Child Psychology, 2016Co-Authors: Lisa-christine Girard, Jean-baptiste Pingault, Orla Doyle, Bruno Falissard, Richard E. TremblayAbstract:Conduct problems have been associated with poor Language development, however the direction of this association in early childhood remains unclear. This study examined the longitudinal directional associations between conduct problems and Expressive Language ability. Children enrolled in the UK Millennium Cohort Study ( N = 14, 004; 50.3 % boys) were assessed at 3 and 5 years of age. Parent reports of conduct problems and standardised assessments of Expressive Language were analyzed using cross-lagged modeling. Conduct problems at 3 years was associated with poorer Expressive Language at 5 years and poorer Expressive Language at 3 years was associated with increased conduct problems by 5 years. The results support reciprocal associations, rather than a specific unidirectional path, which is commonly found with samples of older children. The emergence of problems in either domain can thus negatively impact upon the other over time, albeit the effects were modest. Studies examining the effects of intervention targeting conduct problems and Language acquisition prior to school entry may be warranted in testing the efficacy of prevention programmes related to conduct problems and poor Language ability early in childhood.
-
Expressive Language and prosocial behaviour in early childhood longitudinal associations in the uk millennium cohort study
Open Access publications, 2016Co-Authors: Lisa-christine Girard, Jean-baptiste Pingault, Orla Doyle, Bruno Falissard, Richard E. TremblayAbstract:Background: Early childhood is a crucial period for Language development and building social skills. While distinct, these two processes may impact upon each other. Aims: The current study aimed to identify the directional associations between Expressive Language ability and prosocial behaviour between three and five years of age. Methods: Participants included 14, 004 children and their families enrolled in the UK Millennium Cohort Study (MCS). Children’s Expressive Language and prosocial behaviour were assessed at three and five years of age utilizing standardized assessments and parent reports. Cross-lagged models were used for data analysis. Results: Better Expressive Language at three years was associated with increased prosocial behaviour by five years. No support for the inverse direction of association was found. Conclusions: Children’s early ability to effectively express themselves with others may help in building better social relationships by entry into formal schooling. Programming efforts that are tailored towards enhancing positive behavioural growth and social skills in the toddler years are likely to be effective when Expressive Language is also a targeted component of the toddler’s skill development.
-
Developmental Associations Between Conduct Problems and Expressive Language: Cross-lagged Modeling in a Population-based Sample From the Uk
European Psychiatry, 2015Co-Authors: Lisa-christine Girard, Jean-baptiste Pingault, Orla Doyle, Bruno Falissard, Richard E. TremblayAbstract:Introduction Conduct problems and poor Language development have been previously associated, however the direction of this association in early childhood remains unclear. Aims: This study examined the longitudinal associations between conduct problems and Expressive Language ability from three to five years of age. Auto-regressive, concurrent, and cross-lagged paths were investigated while controlling for the contribution of parenting styles, maternal depression, children's cognitive ability, hyperactivity/inattention, and sex. Methods: Children enrolled in the Millennium Cohort Study (MCS) (N = 17, 184), a population-based sample from the United Kingdom, were assessed at three and five years of age. Parent reports of conduct problems and standardized assessments of Expressive Language were analyzed using a cross-lagged modeling approach. Results Conduct problems at three years was associated with poorer Expressive Language at five years and poorer Expressive Language at three years was associated with increased conduct problems by five years. Conclusions : Overall, the results support reciprocal paths between conduct problems and poorer Expressive Language ability from three to five years of age. Interventions targeting conduct problems, Language acquisition, and parenting in the first five years of life may yield the best results in the prevention of both conduct problems and poorer Expressive Language.
Rhea Paul - One of the best experts on this subject based on the ideXlab platform.
-
Phonological Behavior in Toddlers With Slow Expressive Language Development
Journal of speech and hearing research, 1992Co-Authors: Rhea Paul, Patricia JenningsAbstract:Toddlers with slow Expressive Language development were compared to normally speaking age-mates on three global measures of phonological behavior: the average level of complexity of their syllable ...
-
Maternal Linguistic Input to Toddlers With Slow Expressive Language Development
Journal of speech and hearing research, 1991Co-Authors: Rhea Paul, Terril J. ElwoodAbstract:Maternal speech styles to children between 20 and 34 months of age who were slow to acquire Expressive Language were compared to those of mothers with normally speaking toddlers. Aspects of the mot...
Christopher J. Lonigan - One of the best experts on this subject based on the ideXlab platform.
-
The Role of Otitis Media in the Development of Expressive Language Disorder.
Developmental Psychology, 1992Co-Authors: Christopher J. Lonigan, Janet E. Fischel, Grover J. Whitehurst, David S. Arnold, Marta C. Valdez-menchacaAbstract:The role of otitis media (OM) was investigated in a group of preschool children with a rigorously defined Language impairment: developmental Expressive Language disorder (ELD)
-
the continuity of babble and speech in children with specific Expressive Language delay
Journal of Speech Language and Hearing Research, 1991Co-Authors: Grover J. Whitehurst, Janet E. Fischel, David S. Arnold, Meagan Smith, Christopher J. LoniganAbstract:A natural Language sample of babble and words was obtained for 37 two-year-olds with severe specific Expressive Language delay. Variables derived from this sample were used to predict individual di...
-
Treatment of Early Expressive Language Delay: If, When, and How.
Topics in Language Disorders, 1991Co-Authors: Grover J. Whitehurst, Janet E. Fischel, Christopher J. Lonigan, Marta C. Valdez-menchaca, David S. Arnold, Meagan SmithAbstract:Treatment of early Expressive Language delay: If, when, and how Grover Whitehurst;Janet Fischel;Christopher Lonigan;Marta Valdez-Menchaca;David Arnold;Meagan Smith; Topics in Language Disorders
Howard A Moss - One of the best experts on this subject based on the ideXlab platform.
-
receptive and Expressive Language function of children with symptomatic hiv infection and relationship with disease parameters a longitudinal 24 month follow up study
AIDS, 1997Co-Authors: Pamela L Wolters, Pim Brouwers, Lucy Civitello, Howard A MossAbstract:Objectives: To longitudinally assess the receptive and Expressive Language functioning of children with symptomatic HIV disease and to explore the relationship between immune status, computed tomography (CT) brain scan abnormalities, and Language dysfunction over time. Methods: Children with symptomatic HIV infection were administered an age-appropriate standardized comprehensive Language test and general cognitive measure prior to starting antiretroviral therapy In = 44) and again after 6 months (n = 29) and 24 months (n = 17). CD4 percentage and CT brain scans were also obtained at each evaluation. Results: Expressive Language was significantly more impaired than receptive Language at the baseline, 6- and 24-month evaluations. No significant changes over time were found in receptive or Expressive Language from baseline to after 6 months of antiretroviral therapy, but despite treatment, Language scores declined significantly between 6 and 24 months. Overall cognitive function, however, remained stable from baseline to 24 months. Age-adjusted CD4 percentage increased significantly over the initial 6 months, then remained stable. Overall CT brain scan severity ratings did not change significantly over 24 months. Conclusion: Expressive Language was consistently more impaired than receptive Language over 24 months, further supporting an earlier finding that Expressive Language was differentially affected by HIV in children with symptomatic disease. Both receptive and Expressive Language declined significantly after 24 months despite antiretroviral therapy, although overall cognitive function remained stable. Thus, functioning in some domains may be more vulnerable to the effects of HIV and global measures of cognitive ability may mask such differential changes in specific brain functions.
-
differential receptive and Expressive Language functioning of children with symptomatic hiv disease and relation to ct scan brain abnormalities
Pediatrics, 1995Co-Authors: Pamela L Wolters, Pim Brouwers, Howard A Moss, Philip A PizzoAbstract:Objectives. To investigate the effect of HIV disease on the receptive and Expressive Language of children and the relationship between CT scan brain abnormalities and Language functioning. Methods. Thirty-six children (mean age, 5.5 years; range, 1 through 10 years; 75% vertical transmission; 58% classified as encephalopathic) with symptomatic HIV infection and 20 uninfected siblings (mean age, 7.8 years; range, 3 through 15 years) were administered an age-appropriate comprehensive Language test assessing both receptive and Expressive Language (Reynell Developmental Language Scales or Clinical Evaluation of Language Fundamentals—Revised). Each HIV-infected child had a CT scan of the brain as part of the baseline evaluation, which was rated independently and blindly by two neurologists, for presence and severity of brain abnormalities using a semiquantitative rating system. Results. Expressive Language was significantly more impaired than receptive Language in the overall sample of HIV-infected children. The encephalopathic children scored significantly lower than the non-encephalopathic children, however, the degree of discrepancy between mean receptive and Expressive Language scores was not significantly different between these two groups. The uninfected sibling control group did not have a significant discrepancy between receptive and Expressive Language, and they scored significantly higher than the infected patient group. Greater severity of CT scan abnormalities was significantly correlated with poorer receptive and Expressive Language functioning in the overall HIV-infected sample and a higher discrepancy between receptive and Expressive Language in the encephalopathic group. Conclusion. Pediatric HIV disease is associated with differential receptive and Expressive Language functioning in which Expressive Language is significantly more impaired than receptive Language. The sibling data and CT scan correlations suggest that the observed Language impairments are associated with the direct effects of HIV-related central nervous system disease.
