The Experts below are selected from a list of 213 Experts worldwide ranked by ideXlab platform
John Koo - One of the best experts on this subject based on the ideXlab platform.
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drug induced tactile hallucinations beyond recreational drugs
American Journal of Clinical Dermatology, 2016Co-Authors: Mio Nakamura, John KooAbstract:In monosymptomatic hypochondriacal psychosis (MHP), such as delusional infestation (DI), the patient has a fixed, false, encapsulated belief associated with tactile hallucinations (TH), most commonly Formication, which is defined as cutaneous sensations of crawling, stinging, biting, etc., without evidence of infestation. Drug-induced TH should be considered in patients with suspected MHP. Although recreational drugs such as cocaine, amphetamines, and narcotics are well known to induce TH, many busy practicing dermatologists may not be familiar with other types of medications that can induce TH. A literature search for peer-reviewed articles was conducted in the PubMed, PsychInfo, Cochrane, and Embase databases. For each article, the medication(s) that induced TH was identified in a systematic way. The most commonly reported group of medications to induce TH was anti-Parkisonian agents, followed by antidepressants, prescription stimulants, antihypertensives (propranolol), and antiepileptics. In many cases, other types of hallucinations, such as visual and auditory, were present. Patients also commonly presented with psychiatric comorbidities. Although the conclusions that can be derived from this literature review are limited, it appears that certain medications that alter neurotransmitters, especially dopamine and, less convincingly, norepinephrine and serotonin, can be associated with TH. Drug-induced TH should also be considered in patients presenting with multiple types of hallucinations and patients with existing psychiatric comorbidity. Drug-induced TH, especially with an underlying psychiatric diagnosis that is separate from MHP, may be a more manageable disease entity compared with bona fide MHP.
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Formication without delusions
2014Co-Authors: Tien V Nguyen, Jillian W Wong, John KooAbstract:Mr. Schmidt is a 38 year-old Caucasian man presenting with a 3-month history of extremely bothersome crawling, biting, and stinging sensations. He reported that at times he felt as if “a 1,000 bugs were falling and crawling on my [his] skin.” The patient claimed that no living organisms were involved in causing his skin condition, not only because there was no evidence to suggest this but also because the symptomatology was so bizarre that he knew of no organisms likely to cause this type of discomfort. The onset of these symptoms was not correlated with any particular events or stressors, and he denied recreational drug use. Past medical history was unremarkable. Due to the intensity of the Formication, he was very eager to undergo aggressive therapy to reduce these sensations.
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drug induced Formication and delusions of parasitosis
2014Co-Authors: Tien V Nguyen, Jillian W Wong, John KooAbstract:Mr. Northwood is a 25 year-old Caucasian man, who presented with a chief complaint of being infested by “bugs.” He reported intense, bothersome sensations of crawling, stinging, and biting, which were felt frequently all over this body. He otherwise had a clean bill of health and denied any psychological stress or emotional issues. Upon further questioning, he admitted to regular, heavy use of cocaine for the past 2 years. After he had started experimenting with cocaine, he started to notice these symptoms, which were tolerable at the time. However, the sensations progressively worsened to the point where he could no longer resist the urge to scratch or to pick at his skin. His general practitioner could not determine the cause, and as a result, referred him to your psychodermatology clinic for help.
Robert Meatherall - One of the best experts on this subject based on the ideXlab platform.
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a foxy intoxication
Forensic Science International, 2005Co-Authors: John Wilson, Frank Mcgeorge, Susan Smolinske, Robert MeatherallAbstract:Foxy is the colloquial name for the hallucinogen 5-ethoxy-diisopropyltryptamine (5-MeO-DIPT). A non-fatality involving a 23-year-old Caucasian man who ingested a capsule containing 5-MeO-DIPT is described. He presented to the Emergency Department, not with visual nor auditory hallucinations but with sensory hallucinations, that of Formication and paranoia. He was observed and given supportive care for 4 h, then discharged without any known sequelae. Blood and urine were collected for laboratory analyses. Foxy and its metabolites were identified in urine by gas chromatography‐mass spectrometry. The concentrations of 5-MeO-DIPT in the serum and urine were 0.14 and 1.6 mg/mL, respectively. The drug undergoes oxidative deamination to form 5-methoxy-indole acetic acid. The urinary concentration of this metabolite was 0.17 mg/mL. Also, the urine contained three other related compounds. Two of them have been described in a previous case of 5-MeO-DIPT ingestion as 5methoxy-isopropyltryptamine (5-MeO-IPT) and 5-methoxy-diisopropyltryptamine-N 0 -oxide (5-MeO-DIPT-N 0 -oxide). The third compound was substantially present in the urine and was tentatively identified as 5-hydroxy-diisopropyltryptamine (5-OH-DIPT). Only the parent drug, 5-MeO-DIPT was detected in the serum sample. # 2004 Elsevier Ireland Ltd. All rights reserved.
John Wilson - One of the best experts on this subject based on the ideXlab platform.
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a foxy intoxication
Forensic Science International, 2005Co-Authors: John Wilson, Frank Mcgeorge, Susan Smolinske, Robert MeatherallAbstract:Foxy is the colloquial name for the hallucinogen 5-ethoxy-diisopropyltryptamine (5-MeO-DIPT). A non-fatality involving a 23-year-old Caucasian man who ingested a capsule containing 5-MeO-DIPT is described. He presented to the Emergency Department, not with visual nor auditory hallucinations but with sensory hallucinations, that of Formication and paranoia. He was observed and given supportive care for 4 h, then discharged without any known sequelae. Blood and urine were collected for laboratory analyses. Foxy and its metabolites were identified in urine by gas chromatography‐mass spectrometry. The concentrations of 5-MeO-DIPT in the serum and urine were 0.14 and 1.6 mg/mL, respectively. The drug undergoes oxidative deamination to form 5-methoxy-indole acetic acid. The urinary concentration of this metabolite was 0.17 mg/mL. Also, the urine contained three other related compounds. Two of them have been described in a previous case of 5-MeO-DIPT ingestion as 5methoxy-isopropyltryptamine (5-MeO-IPT) and 5-methoxy-diisopropyltryptamine-N 0 -oxide (5-MeO-DIPT-N 0 -oxide). The third compound was substantially present in the urine and was tentatively identified as 5-hydroxy-diisopropyltryptamine (5-OH-DIPT). Only the parent drug, 5-MeO-DIPT was detected in the serum sample. # 2004 Elsevier Ireland Ltd. All rights reserved.
Frank Mcgeorge - One of the best experts on this subject based on the ideXlab platform.
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a foxy intoxication
Forensic Science International, 2005Co-Authors: John Wilson, Frank Mcgeorge, Susan Smolinske, Robert MeatherallAbstract:Foxy is the colloquial name for the hallucinogen 5-ethoxy-diisopropyltryptamine (5-MeO-DIPT). A non-fatality involving a 23-year-old Caucasian man who ingested a capsule containing 5-MeO-DIPT is described. He presented to the Emergency Department, not with visual nor auditory hallucinations but with sensory hallucinations, that of Formication and paranoia. He was observed and given supportive care for 4 h, then discharged without any known sequelae. Blood and urine were collected for laboratory analyses. Foxy and its metabolites were identified in urine by gas chromatography‐mass spectrometry. The concentrations of 5-MeO-DIPT in the serum and urine were 0.14 and 1.6 mg/mL, respectively. The drug undergoes oxidative deamination to form 5-methoxy-indole acetic acid. The urinary concentration of this metabolite was 0.17 mg/mL. Also, the urine contained three other related compounds. Two of them have been described in a previous case of 5-MeO-DIPT ingestion as 5methoxy-isopropyltryptamine (5-MeO-IPT) and 5-methoxy-diisopropyltryptamine-N 0 -oxide (5-MeO-DIPT-N 0 -oxide). The third compound was substantially present in the urine and was tentatively identified as 5-hydroxy-diisopropyltryptamine (5-OH-DIPT). Only the parent drug, 5-MeO-DIPT was detected in the serum sample. # 2004 Elsevier Ireland Ltd. All rights reserved.
Susan Smolinske - One of the best experts on this subject based on the ideXlab platform.
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a foxy intoxication
Forensic Science International, 2005Co-Authors: John Wilson, Frank Mcgeorge, Susan Smolinske, Robert MeatherallAbstract:Foxy is the colloquial name for the hallucinogen 5-ethoxy-diisopropyltryptamine (5-MeO-DIPT). A non-fatality involving a 23-year-old Caucasian man who ingested a capsule containing 5-MeO-DIPT is described. He presented to the Emergency Department, not with visual nor auditory hallucinations but with sensory hallucinations, that of Formication and paranoia. He was observed and given supportive care for 4 h, then discharged without any known sequelae. Blood and urine were collected for laboratory analyses. Foxy and its metabolites were identified in urine by gas chromatography‐mass spectrometry. The concentrations of 5-MeO-DIPT in the serum and urine were 0.14 and 1.6 mg/mL, respectively. The drug undergoes oxidative deamination to form 5-methoxy-indole acetic acid. The urinary concentration of this metabolite was 0.17 mg/mL. Also, the urine contained three other related compounds. Two of them have been described in a previous case of 5-MeO-DIPT ingestion as 5methoxy-isopropyltryptamine (5-MeO-IPT) and 5-methoxy-diisopropyltryptamine-N 0 -oxide (5-MeO-DIPT-N 0 -oxide). The third compound was substantially present in the urine and was tentatively identified as 5-hydroxy-diisopropyltryptamine (5-OH-DIPT). Only the parent drug, 5-MeO-DIPT was detected in the serum sample. # 2004 Elsevier Ireland Ltd. All rights reserved.