The Experts below are selected from a list of 36759 Experts worldwide ranked by ideXlab platform
Ji-kai Liu - One of the best experts on this subject based on the ideXlab platform.
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triterpenes with unusual modifications from the Fruiting Bodies of the medicinal fungus irpex lacteus
Phytochemistry, 2019Co-Authors: Ji-kai Liu, Tao Feng, Yang Tang, Zhenzhu Zhao, Heping ChenAbstract:Abstract Ten previously undescribed triterpenoid congeners, namely irpeksolactins A–J, together with eighteen known ones, were isolated from the Fruiting Bodies of the rainforest-dwelling medicinal fungus Irpex lacteus. The structures of all the isolates were characterized by extensive spectroscopic approaches, including 1D & 2D NMR and MS spectroscopic methods. Irpeksolactin J displayed selective and weak cytotoxicity against the human lung cancer cell line A549 and the human hepatocellular carcinoma cell line SMMC-7721.
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irpexolidal represents a class of triterpenoid from the Fruiting Bodies of the medicinal fungus irpex lacteus
Journal of Organic Chemistry, 2019Co-Authors: Ji-kai Liu, Tao Feng, Yang Tang, Zhenzhu Zhao, Heping ChenAbstract:Irpexolidal (1), a triterpenoid with an unprecedented carbon skeleton, along with its biogenetic-related compound irpexolide A (2), were isolated from the Fruiting Bodies of the medicinal fungus Irpex lacteus. Irpexolidal features a 6/5/6/5/6/5-fused polycyclic skeletal system which arises from the eburicane-type triterpene by a 6,7- seco-6,8- cyclo pattern. The structures of 1 and 2 were established by means of extensive spectroscopic techniques, ECD calculation, and DP4+ probability based on GIAO NMR chemical shift calculations. The plausible biosynthetic pathways for compounds 1 and 2 were proposed. Their biological activities were evaluated.
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Three new phenyl-ethanediols from the Fruiting Bodies of the mushroom Fomes fomentarius
Journal of Asian Natural Products Research, 2013Co-Authors: Jiang-yuan Zhao, Jian-hai Ding, Ze-jun Dong, Hongbin Zhang, Tao Feng, Ji-kai LiuAbstract:Three new phenyl-ethanediols, (1R)-(3-ethenylphenyl)-1,2-ethanediol (1), (1R)-(3-formylphenyl)-1,2-ethanediol (2), and (1R)-(3-acetophenyl)-1,2-ethanediol (3), were isolated from the Fruiting Bodies of the mushroom Fomes fomentarius, together with two related known compounds, (3-ethylphenyl)-1,2-ethanediol (4) and (4-acetophenyl)-1,2-ethanediol (5). Their structures were elucidated by spectroscopic methods including extensive 2D NMR techniques. Compounds 13 showed weak antimicrobial activity.
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cyathane diterpenoids and nitrogenous terphenyl derivative from the Fruiting Bodies of basidiomycete phellodon niger
Chemical & Pharmaceutical Bulletin, 2010Co-Authors: Shengtao Fang, Ling Zhang, Ji-kai LiuAbstract:Two new cyathane-type diterpenoids, nigernin A and B (1, 2), one new nitrogenous terphenyl derivative, phellodonin (3), together with three known compounds, 2',3'-diacetoxy-3,4,5',6',4 ''-pentahydroxy-p-terphenyl, grifolin, and 4-O-methylgrifolic acid, were isolated from the Fruiting Bodies of basidiomycete Phellodon niger. The structures of these new compounds were elucidated by spectroscopic methods and comparison with the data of known compounds in the literature. All these compounds were isolated from this fungus for the first time.
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a new pigment from the Fruiting Bodies of the basidiomycete lactarius deliciosus
Zeitschrift für Naturforschung B, 2006Co-Authors: Xiaolong Yang, Duqiang Luo, Ji-kai LiuAbstract:A new purple azulene pigment (1) was isolated from the Fruiting Bodies of the basidiomycete Lactarius deliciosus together with one known pigment (2). The structures of the pigments were established on the basis of spectral evidence (MS, IR, 1D- and 2D-NMR experiments).
Jian Zhao - One of the best experts on this subject based on the ideXlab platform.
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structure characterization of polysaccharide isolated from the Fruiting Bodies of tricholoma matsutake
Carbohydrate Polymers, 2010Co-Authors: Xiang Ding, Su Feng, Maotao Li, Jie Tang, Jie Zhang, Zhirong Yang, Jian ZhaoAbstract:Abstract A novel heteropolysaccharide was isolated from the Fruiting Bodies of Tricholoma matsutake through DEAE–cellulose column and Sephadex G-100 column. The T. matsutake polysaccharide (TMP-A) had a molecular weight of 8.89 × 104 Da and was mainly composed of 4-D-Glc:4,6-D-Glc:3-D-Gal:T-D-Xyl and with the ratio of 7:1:1:1. The structural features of TMP-A were investigated by a combination of total hydrolysis, methylation analysis, gas chromatography–mass spectrometry (GC–MS), scanning electron microscope (SEM), infrared (IR) spectra, nuclear magnetic resonance (NMR) spectroscopy and dynamical analysis of the atomic force microscope (AFM) studies. The results indicated that TMP-A had a backbone of 1,4-β-glucopyranos which branches at O-6 composed of an (1 → 3)-α-galactopyranose residue and terminated with α-xylopyranose residue. Chain conformation study showed that the polysaccharide took random coil compact conformation.
Joan E Strassmann - One of the best experts on this subject based on the ideXlab platform.
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Fruiting Bodies of the social amoeba dictyostelium discoideum increase spore transport by drosophila
BMC Evolutionary Biology, 2014Co-Authors: Jeff Smith, David C Queller, Joan E StrassmannAbstract:Background Many microbial phenotypes are the product of cooperative interactions among cells, but their putative fitness benefits are often not well understood. In the cellular slime mold Dictyostelium discoideum, unicellular amoebae aggregate when starved and form multicellular Fruiting Bodies in which stress-resistant spores are held aloft by dead stalk cells. Fruiting Bodies are thought to be adaptations for dispersing spores to new feeding sites, but this has not been directly tested. Here we experimentally test whether Fruiting Bodies increase the rate at which spores are acquired by passing invertebrates.
Yang Tang - One of the best experts on this subject based on the ideXlab platform.
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triterpenes with unusual modifications from the Fruiting Bodies of the medicinal fungus irpex lacteus
Phytochemistry, 2019Co-Authors: Ji-kai Liu, Tao Feng, Yang Tang, Zhenzhu Zhao, Heping ChenAbstract:Abstract Ten previously undescribed triterpenoid congeners, namely irpeksolactins A–J, together with eighteen known ones, were isolated from the Fruiting Bodies of the rainforest-dwelling medicinal fungus Irpex lacteus. The structures of all the isolates were characterized by extensive spectroscopic approaches, including 1D & 2D NMR and MS spectroscopic methods. Irpeksolactin J displayed selective and weak cytotoxicity against the human lung cancer cell line A549 and the human hepatocellular carcinoma cell line SMMC-7721.
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irpexolidal represents a class of triterpenoid from the Fruiting Bodies of the medicinal fungus irpex lacteus
Journal of Organic Chemistry, 2019Co-Authors: Ji-kai Liu, Tao Feng, Yang Tang, Zhenzhu Zhao, Heping ChenAbstract:Irpexolidal (1), a triterpenoid with an unprecedented carbon skeleton, along with its biogenetic-related compound irpexolide A (2), were isolated from the Fruiting Bodies of the medicinal fungus Irpex lacteus. Irpexolidal features a 6/5/6/5/6/5-fused polycyclic skeletal system which arises from the eburicane-type triterpene by a 6,7- seco-6,8- cyclo pattern. The structures of 1 and 2 were established by means of extensive spectroscopic techniques, ECD calculation, and DP4+ probability based on GIAO NMR chemical shift calculations. The plausible biosynthetic pathways for compounds 1 and 2 were proposed. Their biological activities were evaluated.
Heping Chen - One of the best experts on this subject based on the ideXlab platform.
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triterpenes with unusual modifications from the Fruiting Bodies of the medicinal fungus irpex lacteus
Phytochemistry, 2019Co-Authors: Ji-kai Liu, Tao Feng, Yang Tang, Zhenzhu Zhao, Heping ChenAbstract:Abstract Ten previously undescribed triterpenoid congeners, namely irpeksolactins A–J, together with eighteen known ones, were isolated from the Fruiting Bodies of the rainforest-dwelling medicinal fungus Irpex lacteus. The structures of all the isolates were characterized by extensive spectroscopic approaches, including 1D & 2D NMR and MS spectroscopic methods. Irpeksolactin J displayed selective and weak cytotoxicity against the human lung cancer cell line A549 and the human hepatocellular carcinoma cell line SMMC-7721.
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irpexolidal represents a class of triterpenoid from the Fruiting Bodies of the medicinal fungus irpex lacteus
Journal of Organic Chemistry, 2019Co-Authors: Ji-kai Liu, Tao Feng, Yang Tang, Zhenzhu Zhao, Heping ChenAbstract:Irpexolidal (1), a triterpenoid with an unprecedented carbon skeleton, along with its biogenetic-related compound irpexolide A (2), were isolated from the Fruiting Bodies of the medicinal fungus Irpex lacteus. Irpexolidal features a 6/5/6/5/6/5-fused polycyclic skeletal system which arises from the eburicane-type triterpene by a 6,7- seco-6,8- cyclo pattern. The structures of 1 and 2 were established by means of extensive spectroscopic techniques, ECD calculation, and DP4+ probability based on GIAO NMR chemical shift calculations. The plausible biosynthetic pathways for compounds 1 and 2 were proposed. Their biological activities were evaluated.
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Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum
2019Co-Authors: Tao Feng, Heping Chen, Xiao-qing Gan, Yun-li Zhao, Shuai-bing Zhang, Yong-sheng Zheng, Huan Sun, Rong HuangAbstract:Two new Tricholoma terpenoids, tricholopardins A and B, were isolated from the Fruiting Bodies of the basidiomycetes Tricholoma pardinum. Their structures were elucidated by spectroscopic methods, as well as electronic circular dichroism and optical rotatory dispersion calculations. Tricholopardin A potently inhibited nitric oxide production in lipopolysaccharide-induced RAW264.7 macrophages with an IC50 of 0.08 μM. Its anti-inflammatory effects on three inflammatory mediators were also evaluated. A plausible biosynthetic pathway for these products is discussed
