The Experts below are selected from a list of 14409 Experts worldwide ranked by ideXlab platform
Tracy I George - One of the best experts on this subject based on the ideXlab platform.
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assembly and evaluation of an inventory of guidelines that are available to support clinical hematology laboratory practice
International Journal of Laboratory Hematology, 2015Co-Authors: Catherine P M Hayward, Tracy I George, Karen A Moffat, Maria ProytchevaAbstract:Summary Introduction Practice guidelines provide helpful support for clinical laboratories. Our goal was to assemble an inventory of publically listed guidelines on hematology laboratory topics, to create a resource for laboratories and for assessing gaps in practice-focused guidelines. Methods PubMed and website searches were conducted to assemble an inventory of hematology laboratory-focused guidelines. Exclusions included annual, technical, or collaborative study reports, clinically focused guidelines, position papers, nomenclature, and calibration documents. Results Sixty-eight guidelines were identified on hematology laboratory practice topics from 12 organizations, some as joint guidelines. The median year of publication was 2010 and 15% were >10 years old. Coagulation topics had the largest numbers of guidelines, whereas some areas of practice had few guidelines. A minority of guidelines showed evidence of periodic updates, as some organizations did not remove or identify outdated guidelines. Conclusions This inventory of current practice guidelines will encourage awareness and uptake of guideline recommendations by the worldwide hematology laboratory community, with the International Society for Laboratory Hematology facilitating ongoing updates. There is a need to encourage best guideline development practices, to ensure that hematology laboratory community has current, high-quality, and evidence-based practice guidelines that cover the full scope of hematology laboratory practice.
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evaluation of the beckman coulter unicel dxh 800 beckman coulter lh 780 and abbott diagnostics cell dyn sapphire hematology analyzers on adult specimens in a tertiary care hospital
American Journal of Clinical Pathology, 2011Co-Authors: Brent T Tan, Armando J Nava, Tracy I GeorgeAbstract:We evaluated the new Beckman Coulter DxH 800 hematology analyzer (Beckman Coulter, Miami, FL) vs the Abbott Diagnostics Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA) and Beckman Coulter LH 780 hematology analyzers using 430 adult specimens. The DxH 800 provided a CBC and differential that correlated well with those of the Sapphire and LH 780, with most parameters showing correlation coefficients (r) of more than 0.97. In the instrument vs 400-cell manual differential comparison, all 3 instruments showed similar and acceptable accuracy to the reference method except for nucleated RBC (NRBC) enumeration, in which the DxH 800 and Sapphire outperformed the LH 780. We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency, sensitivity, and specificity of the DxH 800 were 77.0%, 87.1%, and 73.0%, respectively, compared with the Sapphire at 75.8%, 93.5%, and 68.8%, respectively, and LH 780 at 66.1%, 93.5%, and 55.3%, respectively.
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evaluation of the beckman coulter unicel dxh 800 and abbott diagnostics cell dyn sapphire hematology analyzers on pediatric and neonatal specimens in a tertiary care hospital
American Journal of Clinical Pathology, 2011Co-Authors: Armando J Nava, Tracy I GeorgeAbstract:We evaluated the new UniCel DxH 800 hematology analyzer (Beckman Coulter, Miami, FL) vs the Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA) using 156 pediatric specimens in Microtainer tubes (Becton Dickinson, Franklin Lakes, NJ). The CBC and differential showed good interinstrument correlation, including WBCs ( r = 0.995), RBCs ( r = 0.992), hemoglobin ( r = 0.998), mean corpuscular volume ( r = 0.988), platelets ( r = 0.997), neutrophils ( r = 0.988), lymphocytes ( r = 0.984), monocytes ( r = 0.815), eosinophils ( r = 0.840), basophils ( r = 0.049), and nucleated RBCs (NRBCs; r = 0.906). In the instrument vs 400-cell manual differential comparison, the DxH 800 and Sapphire showed comparable performance for nearly all parameters except for NRBCs, for which the DxH 800 correlated better ( r = 0.989) than the Sapphire ( r = 0.906). We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency of the DxH 800 was 78.0% vs the Sapphire at 68.1%. Both instruments showed identical sensitivity (91.1%), but the specificity for the DxH 800 (71.9%) was higher than that of the Sapphire (57.3%).
Armando J Nava - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the beckman coulter unicel dxh 800 beckman coulter lh 780 and abbott diagnostics cell dyn sapphire hematology analyzers on adult specimens in a tertiary care hospital
American Journal of Clinical Pathology, 2011Co-Authors: Brent T Tan, Armando J Nava, Tracy I GeorgeAbstract:We evaluated the new Beckman Coulter DxH 800 hematology analyzer (Beckman Coulter, Miami, FL) vs the Abbott Diagnostics Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA) and Beckman Coulter LH 780 hematology analyzers using 430 adult specimens. The DxH 800 provided a CBC and differential that correlated well with those of the Sapphire and LH 780, with most parameters showing correlation coefficients (r) of more than 0.97. In the instrument vs 400-cell manual differential comparison, all 3 instruments showed similar and acceptable accuracy to the reference method except for nucleated RBC (NRBC) enumeration, in which the DxH 800 and Sapphire outperformed the LH 780. We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency, sensitivity, and specificity of the DxH 800 were 77.0%, 87.1%, and 73.0%, respectively, compared with the Sapphire at 75.8%, 93.5%, and 68.8%, respectively, and LH 780 at 66.1%, 93.5%, and 55.3%, respectively.
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evaluation of the beckman coulter unicel dxh 800 and abbott diagnostics cell dyn sapphire hematology analyzers on pediatric and neonatal specimens in a tertiary care hospital
American Journal of Clinical Pathology, 2011Co-Authors: Armando J Nava, Tracy I GeorgeAbstract:We evaluated the new UniCel DxH 800 hematology analyzer (Beckman Coulter, Miami, FL) vs the Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA) using 156 pediatric specimens in Microtainer tubes (Becton Dickinson, Franklin Lakes, NJ). The CBC and differential showed good interinstrument correlation, including WBCs ( r = 0.995), RBCs ( r = 0.992), hemoglobin ( r = 0.998), mean corpuscular volume ( r = 0.988), platelets ( r = 0.997), neutrophils ( r = 0.988), lymphocytes ( r = 0.984), monocytes ( r = 0.815), eosinophils ( r = 0.840), basophils ( r = 0.049), and nucleated RBCs (NRBCs; r = 0.906). In the instrument vs 400-cell manual differential comparison, the DxH 800 and Sapphire showed comparable performance for nearly all parameters except for NRBCs, for which the DxH 800 correlated better ( r = 0.989) than the Sapphire ( r = 0.906). We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency of the DxH 800 was 78.0% vs the Sapphire at 68.1%. Both instruments showed identical sensitivity (91.1%), but the specificity for the DxH 800 (71.9%) was higher than that of the Sapphire (57.3%).
Brent T Tan - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the beckman coulter unicel dxh 800 beckman coulter lh 780 and abbott diagnostics cell dyn sapphire hematology analyzers on adult specimens in a tertiary care hospital
American Journal of Clinical Pathology, 2011Co-Authors: Brent T Tan, Armando J Nava, Tracy I GeorgeAbstract:We evaluated the new Beckman Coulter DxH 800 hematology analyzer (Beckman Coulter, Miami, FL) vs the Abbott Diagnostics Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA) and Beckman Coulter LH 780 hematology analyzers using 430 adult specimens. The DxH 800 provided a CBC and differential that correlated well with those of the Sapphire and LH 780, with most parameters showing correlation coefficients (r) of more than 0.97. In the instrument vs 400-cell manual differential comparison, all 3 instruments showed similar and acceptable accuracy to the reference method except for nucleated RBC (NRBC) enumeration, in which the DxH 800 and Sapphire outperformed the LH 780. We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency, sensitivity, and specificity of the DxH 800 were 77.0%, 87.1%, and 73.0%, respectively, compared with the Sapphire at 75.8%, 93.5%, and 68.8%, respectively, and LH 780 at 66.1%, 93.5%, and 55.3%, respectively.
Vinod Chandran - One of the best experts on this subject based on the ideXlab platform.
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Segmentation of White Blood Cell, Nucleus and Cytoplasm in Digital Haematology Microscope Images: A Review-Challenges, Current and Future Potential Techniques
IEEE Reviews in Biomedical Engineering, 2024Co-Authors: Khamael Al-dulaimi, Jasmine Banks, Kien Nguyen, Aiman Al-sabaawi, Inmaculada Tomeo-reyes, Vinod ChandranAbstract:Segmentation of white blood cells in digital Haematology microscope images represents one of the major tools in the diagnosis and evaluation of blood disorders. Pathological examinations are being the gold standard in many Haematology and histophathology, and also play a key role in the diagnosis of diseases. In clinical diagnosis, white blood cells are analysed by pathologists from peripheral blood smears samples of patients. This analysis is mainly based on morphological features and characteristics of the white blood cells and their nuclei and cytoplasm, including, shapes, sizes, colours, textures, maturity stages and staining processes. Recently, Computer Aided Diagnosis techniques have been rapidly growing in the digital Haematology area related to white blood cells, and their nuclei and cytoplasm detection, as well as their segmentation and classification techniques. In digital Haematology image analysis, these techniques have played and will continue to play, a vital role for providing traceable clinical information, consolidating pertinent second opinions, and minimizing human intervention. This study outlines, discusses, and introduces the major trends from a particular review of detection and segmentation methods for white blood cells and their nuclei and cytoplasm from digital Haematology microscope images.
Khamael Al-dulaimi - One of the best experts on this subject based on the ideXlab platform.
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Segmentation of White Blood Cell, Nucleus and Cytoplasm in Digital Haematology Microscope Images: A Review-Challenges, Current and Future Potential Techniques
IEEE Reviews in Biomedical Engineering, 2024Co-Authors: Khamael Al-dulaimi, Jasmine Banks, Kien Nguyen, Aiman Al-sabaawi, Inmaculada Tomeo-reyes, Vinod ChandranAbstract:Segmentation of white blood cells in digital Haematology microscope images represents one of the major tools in the diagnosis and evaluation of blood disorders. Pathological examinations are being the gold standard in many Haematology and histophathology, and also play a key role in the diagnosis of diseases. In clinical diagnosis, white blood cells are analysed by pathologists from peripheral blood smears samples of patients. This analysis is mainly based on morphological features and characteristics of the white blood cells and their nuclei and cytoplasm, including, shapes, sizes, colours, textures, maturity stages and staining processes. Recently, Computer Aided Diagnosis techniques have been rapidly growing in the digital Haematology area related to white blood cells, and their nuclei and cytoplasm detection, as well as their segmentation and classification techniques. In digital Haematology image analysis, these techniques have played and will continue to play, a vital role for providing traceable clinical information, consolidating pertinent second opinions, and minimizing human intervention. This study outlines, discusses, and introduces the major trends from a particular review of detection and segmentation methods for white blood cells and their nuclei and cytoplasm from digital Haematology microscope images.
