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Jean Bousquet - One of the best experts on this subject based on the ideXlab platform.
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operational definition of active and Healthy Ageing aha a conceptual framework
Journal of Nutrition Health & Aging, 2015Co-Authors: Jean Bousquet, D Kuh, Mike Bewick, T Standberg, John Farrell, R Pengelly, M E Joel, Rodriguez L ManasAbstract:Health is a multi-dimensional concept, capturing how people feel and function. The broad concept of Active and Healthy Ageing was proposed by the World Health Organisation (WHO) as the process of optimizing opportunities for health to enhance quality of life as people age. It applies to both individuals and population groups. A universal Active and Healthy Ageing definition is not available and it may differ depending on the purpose of the definition and/or the questions raised. While the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) has had a major impact, a definition of Active and Healthy Ageing is urgently needed. A meeting was organised in Montpellier, France, October 20-21, 2014 as the annual conference of the EIP on AHA Reference Site MACVIA-LR (Contre les Maladies Chroniques pour un Vieillissement Actif en Languedoc Roussillon) to propose an operational definition of Active and Healthy Ageing including tools that may be used for this. The current paper describes the rationale and the process by which the aims of the meeting will be reached.
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operative definition of active and Healthy Ageing aha meeting report montpellier october 20 21 2014
European Geriatric Medicine, 2015Co-Authors: Jean Bousquet, D Kuh, Mike Bewick, John Farrell, R Pengelly, M E Joel, Rodriguez L Manas, T Strandberg, J MercierAbstract:The broad concept of Active and Healthy Ageing was proposed by WHO as the process of optimizing opportunities for health to enhance quality of life as people age. It applies to both individuals and population groups. A universal active and Healthy Ageing definition is not available and may differ depending on the purpose of the definition and/or the questions raised. The European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) has had a major impact but a definition of Active and Healthy Ageing is urgently needed. A meeting was organised in Montpellier October 20-21, 2014 as the annual conference of the EIP on AHA Reference Site MACVIA-LR (contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussillon). The goal of the meeting was to propose an operational definition of Active and Healthy Ageing as well as tools that may be used for this definition. The current paper provides a summary of the plenary presentations that were given during the meeting.
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macvia lr reference site of the european innovation partnership on active and Healthy Ageing eip on aha in languedoc roussillon
European Geriatric Medicine, 2014Co-Authors: Jean Bousquet, T Camuzat, C Bourquin, Philippe Auge, P Domy, J Bringer, M Aoustin, Rodolphe Bourret, N Best, O JonquetAbstract:Abstract The Region Languedoc-Roussillon is the umbrella organisation for an interconnected and integrated project on AHA covering the 3 pillars of the European Innovation Partnership on Active and Healthy Ageing. All sub-activities (A1: electronic pharmaceutical file, A2: falls prevention initiative, A3: frailty, B3: chronic respiratory diseases, chronic diseases with comorbidities, oral health and hepatitis virus C chronic infection, C2 and D4 active and independent living and handicap) are included in MACVIA-LR that has a strong political commitment and includes all stakeholders (public, private, patients, policy makers). It is one of the Reference Sites of the European Innovation Partnership on Active and Healthy Ageing built around chronic diseases, Ageing and handicap. The framework of MACVIA-LR has the vision that the prevention and management of CDs is essential for AHA promotion and for the reduction of handicap. The main objective of MACVIA-LR is to develop innovative solutions for a network of Living Labs in order to improve the care of patients affected by CDs in the Languedoc-Roussillon area and to disseminate the innovation.
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integrated care pathways for airway diseases airways icps european innovation partnership on active and Healthy Ageing action plan b3 mechanisms of the development of allergy medall wp10 gard global alliance against chronic respiratory diseases who research demonstration project
2014Co-Authors: Jean Bousquet, C Bachert, Antonio Addis, Ian M Adcock, Ioana Agache, Alvar Agusti, Albert Alonso, Chunxue Bai, Cristina Barbara, L BeckAbstract:The objective of Integrated Care Pathways for Airway Diseases (AIRWAYS-ICPs) is to launch a collaboration to develop multi-sector care pathways for chronic respiratory diseases in European countries and regions. AIRWAYS-ICPs has strategic relevance to the European Union Health Strategy and will add value to existing public health knowledge by: 1) proposing a common framework of care pathways for chronic respiratory diseases, which will facilitate comparability and trans-national initiatives; 2) informing cost-effective policy development, strengthening in particular those on smoking and environment exposure; 3) aiding risk stratification in chronic disease patients, using a common strategy; 4) having a significant impact on the health of citizens in the short term (reduction of morbidity, improvement of education in children and of work in adults) and in the long-term (Healthy Ageing); 5) proposing a common simulation tool to assist physicians; and 6) ultimately reducing the healthcare burden (emergency visits, avoidable hospitalisations, disability and costs) while improving quality of life. In the longer term, the incidence of disease may be reduced by innovative prevention strategies. AIRWAYS-ICPs was initiated by Area 5 of the Action Plan B3 of the European Innovative Partnership on Active and Healthy Ageing. All stakeholders are involved (health and social care, patients, and policy makers). European Respiratory Journal erj00146-2014.3d 17/4/14 10:01:30 The Charlesworth Group, Wakefield +44(0)1924 369598 Rev 7.51n/W (Jan 2
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impact of early diagnosis and control of chronic respiratory diseases on active and Healthy Ageing a debate at the european union parliament
Allergy, 2013Co-Authors: Jean Bousquet, T Camuzat, C C Tanasescu, Josep M Anto, Francesco Blasi, A Neou, S Palkonen, Nikolaos G PapadopoulosAbstract:A debate at the European Union Parliament was held on 13 November 2012 on the Impact of early diagnosis and control of chronic respiratory diseases on Active and Healthy Ageing (AHA). The debate was held under the auspices of theCyprus Presidency of the European Union (2012) and represents a follow-up of the priorities of the Polish Presidency of the European Union (2011). It highlighted the importance of early life events on the occurrence of chronic respiratory diseases later in life and their impact on active and Healthy Ageing. Epidemiologic evidence was followed by actions that should be taken to prevent and manage chronic respiratory diseases in children. The debate ended by practical, feasible and achievable projects, demonstrating the strength of the political action in the field. Three projects will be initiated from this debate: The first will be a meeting sponsored by the Region Languedoc-Roussillon on the developmental origins of chronic diseases and Ageing: from research to policies and value creation. The second project is being led by the WHO Collaborating Centre for Asthma and Rhinitis: Prevention of Asthma, Prevention of Allergy (PAPA). The third project is the GA2LEN sentinel network.
Simon L Bacon - One of the best experts on this subject based on the ideXlab platform.
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taking up physical activity in later life and Healthy Ageing the english longitudinal study of Ageing
British Journal of Sports Medicine, 2014Co-Authors: Mark Hamer, Kim L Lavoie, Simon L BaconAbstract:Background Physical activity is associated with improved overall health in those people who survive to older ages, otherwise conceptualised as Healthy Ageing. Previous studies have examined the effects of mid-life physical activity on Healthy Ageing, but not the effects of taking up activity later in life. We examined the association between physical activity and Healthy Ageing over 8 years of follow-up. Methods Participants were 3454 initially disease-free men and women (aged 63.7±8.9 years at baseline) from the English Longitudinal Study of Ageing, a prospective study of community dwelling older adults. Self-reported physical activity was assessed at baseline (2002–2003) and through follow-up. Healthy Ageing, assessed at 8 years of follow-up (2010-2011), was defined as those participants who survived without developing major chronic disease, depressive symptoms, physical or cognitive impairment. Results At follow-up, 19.3% of the sample was defined as Healthy Ageing. In comparison with inactive participants, moderate (OR, 2.67, 95% CI 1.95 to 3.64), or vigorous activity (3.53, 2.54 to 4.89) at least once a week was associated with Healthy Ageing, after adjustment for age, sex, smoking, alcohol, marital status and wealth. Becoming active (multivariate adjusted, 3.37, 1.67 to 6.78) or remaining active (7.68, 4.18 to 14.09) was associated with Healthy Ageing in comparison with remaining inactive over follow-up. Conclusions Sustained physical activity in older age is associated with improved overall health. Significant health benefits were even seen among participants who became physically active relatively late in life.
D Kuh - One of the best experts on this subject based on the ideXlab platform.
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operational definition of active and Healthy Ageing aha a conceptual framework
Journal of Nutrition Health & Aging, 2015Co-Authors: Jean Bousquet, D Kuh, Mike Bewick, T Standberg, John Farrell, R Pengelly, M E Joel, Rodriguez L ManasAbstract:Health is a multi-dimensional concept, capturing how people feel and function. The broad concept of Active and Healthy Ageing was proposed by the World Health Organisation (WHO) as the process of optimizing opportunities for health to enhance quality of life as people age. It applies to both individuals and population groups. A universal Active and Healthy Ageing definition is not available and it may differ depending on the purpose of the definition and/or the questions raised. While the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) has had a major impact, a definition of Active and Healthy Ageing is urgently needed. A meeting was organised in Montpellier, France, October 20-21, 2014 as the annual conference of the EIP on AHA Reference Site MACVIA-LR (Contre les Maladies Chroniques pour un Vieillissement Actif en Languedoc Roussillon) to propose an operational definition of Active and Healthy Ageing including tools that may be used for this. The current paper describes the rationale and the process by which the aims of the meeting will be reached.
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a proposed panel of biomarkers of Healthy Ageing
BMC Medicine, 2015Co-Authors: Jose Lara, D Kuh, Rachel Cooper, Jack Nissan, Annie T Ginty, Kaytee Khaw, Ian J Deary, Janet M Lord, John C MathersAbstract:There is no criterion reference for assessing Healthy Ageing and this creates difficulties when conducting and comparing research on Ageing across studies. A cardinal feature of Ageing is loss of function which translates into wide-ranging consequences for the individual and for family, carers and society. We undertook comprehensive reviews of the literature searching for biomarkers of Ageing on five Ageing-related domains including physical capability and cognitive, physiological and musculoskeletal, endocrine and immune functions. Where available, we used existing systematic reviews, meta-analyses and other authoritative reports such as the recently launched NIH Toolbox for assessment of neurological and behavioural function, which includes test batteries for cognitive and motor function (the latter described here as physical capability). We invited international experts to comment on our draft recommendations. In addition, we hosted an experts workshop in Newcastle, UK, on 22–23 October 2012, aiming to help capture the state-of-the-art in this complex area and to provide an opportunity for the wider Ageing research community to critique the proposed panel of biomarkers. Here we have identified important biomarkers of Healthy Ageing classified as subdomains of the main areas proposed. Cardiovascular and lung function, glucose metabolism and musculoskeletal function are key subdomains of physiological function. Strength, locomotion, balance and dexterity are key physical capability subdomains. Memory, processing speed and executive function emerged as key subdomains of cognitive function. Markers of the HPA-axis, sex hormones and growth hormones were important biomarkers of endocrine function. Finally, inflammatory factors were identified as important biomarkers of immune function. We present recommendations for a panel of biomarkers that address these major areas of function which decline during Ageing. This biomarker panel may have utility in epidemiological studies of human Ageing, in health surveys of older people and as outcomes in intervention studies that aim to promote Healthy Ageing. Further, the inclusion of the same common panel of measures of Healthy Ageing in diverse study designs and populations may enhance the value of those studies by allowing the harmonisation of surrogate endpoints or outcome measures, thus facilitating less equivocal comparisons between studies and the pooling of data across studies.
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operative definition of active and Healthy Ageing aha meeting report montpellier october 20 21 2014
European Geriatric Medicine, 2015Co-Authors: Jean Bousquet, D Kuh, Mike Bewick, John Farrell, R Pengelly, M E Joel, Rodriguez L Manas, T Strandberg, J MercierAbstract:The broad concept of Active and Healthy Ageing was proposed by WHO as the process of optimizing opportunities for health to enhance quality of life as people age. It applies to both individuals and population groups. A universal active and Healthy Ageing definition is not available and may differ depending on the purpose of the definition and/or the questions raised. The European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) has had a major impact but a definition of Active and Healthy Ageing is urgently needed. A meeting was organised in Montpellier October 20-21, 2014 as the annual conference of the EIP on AHA Reference Site MACVIA-LR (contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc Roussillon). The goal of the meeting was to propose an operational definition of Active and Healthy Ageing as well as tools that may be used for this definition. The current paper provides a summary of the plenary presentations that were given during the meeting.
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a life course approach to Healthy Ageing maintaining physical capability
Proceedings of the Nutrition Society, 2014Co-Authors: D Kuh, Sathya Karunananthan, Howard Bergman, Rachel CooperAbstract:Research on Healthy Ageing lacks an agreed conceptual framework and has not adequately taken into account the growing evidence that social and biological factors from early life onwards affect later health. We conceptualise Healthy Ageing within a life-course framework, separating Healthy biological Ageing (in terms of optimal physical and cognitive functioning, delaying the onset of chronic diseases, and extending length of life for as long as possible) from changes in psychological and social wellbeing. We summarise the findings of a review of Healthy Ageing indicators, focusing on objective measures of physical capability, such as tests of grip strength, walking speed, chair rises and standing balance, which aim to capture physical functioning at the individual level, assessing the capacity to undertake the physical tasks of daily living. There is robust evidence that higher scores on these measures are associated with lower rates of mortality, and more limited evidence of lower risk of morbidity, and of age-related patterns of change. Drawing on a research collaboration of UK cohort studies, we summarise what is known about the influences on physical capability in terms of lifetime socioeconomic position, body size and lifestyle, and underlying physiology and genetics; the evidence to date supports a broad set of factors already identified as risk factors for chronic diseases. We identify a need for larger longitudinal studies to investigate age-related change and ethnic diversity in these objective measures, the dynamic relationships between them, and how they relate to other component measures of Healthy Ageing. Robust evidence across cohort studies, using standardised measures within a clear conceptual framework, will benefit policy and practice to promote Healthy Ageing.
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a life course approach to Healthy Ageing
2013Co-Authors: D KuhAbstract:The life course epidemiological approach extends the WHO Healthy Ageing initiative by investigating how physical and mental capacities change across life; how they vary by birth cohort, socioeconomic position, gender, and ethnicity; and the extent to which experience and exposures earlier in life have long-term consequences for later life capacities, disability, and chronic diseases. This chapter summarises some of the social and biomedical factors from childhood that have long-term consequences for intrinsic capacities, and how a lower level and/or an accelerated decline in capacities during early and mid-adulthood can identify those at greatest risk of subsequent disability and disease. Promotion of Healthy Ageing requires preventive strategies that enhance capacities during growth and development, maintain them for as long as possible after maturity, and slow down their rate of decline.
Alessandra Marengoni - One of the best experts on this subject based on the ideXlab platform.
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multimorbidity care model recommendations from the consensus meeting of the joint action on chronic diseases and promoting Healthy Ageing across the life cycle ja chrodis
Health Policy, 2018Co-Authors: Katie Palmer, Alessandra Marengoni, Maria Joao Forjaz, Elena Jureviciene, Tiina Laatikainen, Federica Mammarella, Christiane Muth, Rokas Navickas, Alexandra PradostorresAbstract:Patients with multimorbidity have complex health needs but, due to the current traditional disease-oriented approach, they face a highly fragmented form of care that leads to inefficient, ineffective, and possibly harmful clinical interventions. There is limited evidence on available integrated and multidimensional care pathways for multimorbid patients. An expert consensus meeting was held to develop a framework for care of multimorbid patients that can be applied across Europe, within a project funded by the European Union; the Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS). The experts included a diverse group representing care providers and patients, and included general practitioners, family medicine physicians, neurologists, geriatricians, internists, cardiologists, endocrinologists, diabetologists, epidemiologists, psychologists, and representatives from patient organizations. Sixteen components across five domains were identified (Delivery of Care; Decision Support; Self Management Support; Information Systems and Technology; and Social and Community Resources). The description and aim of each component are described in these guidelines, along with a summary of key characteristics and relevance to multimorbid patients. Due to the lack of evidence-based recommendations specific to multimorbid patients, this care model needs to be assessed and validated in different European settings to examine specifically how multimorbid patients will benefit from this care model, and whether certain components have more importance than others.
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time to face the challenge of multimorbidity a european perspective from the joint action on chronic diseases and promoting Healthy Ageing across the life cycle ja chrodis
European Journal of Internal Medicine, 2015Co-Authors: Graziano Onder, Katie Palmer, Federica Mammarella, Rokas Navickas, E Jurevicienė, Mirela Strandzheva, P M Mannucci, S Pecorelli, Alessandra MarengoniAbstract:Abstract Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) in the context of the 2nd EU Health Programme 2008–2013. The present manuscript summarizes first results of the JA-CHRODIS, focuses on the identification of a population with multimorbidity who has a high or very high care demand. Identification of characteristics of multimorbid patients associated with a high rate of resource consumption and negative health outcomes is necessary to define a target population who can benefit from interventions. Indeed, multimorbidity alone cannot explain the complexity of care needs and further, stratification of the general population based on care needs is necessary for allocating resources and developing personalized, cost-efficient, and patient-centered care plans. Based on analyses of large databases from European countries a profile of the most care-demanding patients with multimorbidity is defined. Several factors associated with adverse health outcomes and resource consumption among patients with multimorbidity were identified in these analyses, including disease patterns, physical function, mental health, and socioeconomic status. These results underline that a global assessment is needed to identify patients with multimorbidity who are at risk of negative health outcomes and that a comprehensive approach, targeting not only diseases, but also social, cognitive, and functional problems should be adopted for these patients.
Nikolaos G Papadopoulos - One of the best experts on this subject based on the ideXlab platform.
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impact of early diagnosis and control of chronic respiratory diseases on active and Healthy Ageing a debate at the european union parliament
Allergy, 2013Co-Authors: Jean Bousquet, T Camuzat, C C Tanasescu, Josep M Anto, Francesco Blasi, A Neou, S Palkonen, Nikolaos G PapadopoulosAbstract:A debate at the European Union Parliament was held on 13 November 2012 on the Impact of early diagnosis and control of chronic respiratory diseases on Active and Healthy Ageing (AHA). The debate was held under the auspices of theCyprus Presidency of the European Union (2012) and represents a follow-up of the priorities of the Polish Presidency of the European Union (2011). It highlighted the importance of early life events on the occurrence of chronic respiratory diseases later in life and their impact on active and Healthy Ageing. Epidemiologic evidence was followed by actions that should be taken to prevent and manage chronic respiratory diseases in children. The debate ended by practical, feasible and achievable projects, demonstrating the strength of the political action in the field. Three projects will be initiated from this debate: The first will be a meeting sponsored by the Region Languedoc-Roussillon on the developmental origins of chronic diseases and Ageing: from research to policies and value creation. The second project is being led by the WHO Collaborating Centre for Asthma and Rhinitis: Prevention of Asthma, Prevention of Allergy (PAPA). The third project is the GA2LEN sentinel network.
