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Thiti Snabboon - One of the best experts on this subject based on the ideXlab platform.

  • Thyrotoxic Hypokalemic Periodic Paralysis Triggered by Dexamethasone Administration.
    Acta Medica (Hradec Kralove Czech Republic), 2020
    Co-Authors: Waraporn Polamaung, Jaruwan Kongkit, Parichat Yimnoi, Patchaya Boonchaya-anant, Thiti Snabboon
    Abstract:

    Thyrotoxic Hypokalemic Periodic Paralysis (THPP) is a disease characterized by recurrent episodes of muscle weakness due to intracellular potassium shifting in the presence of high levels of thyroid hormone. It occurs more commonly amongst young Asian men with underlying Graves' disease. Attacks are commonly precipitated by ingestion of carbohydrate-rich meals or alcohols, stress or strenuous exercise. Herein, we describe an adult Thai man suffering from a Hypokalemic Periodic Paralysis attack after receiving a dexamethasone injection. The diagnosis of Graves' disease was confirmed by his thyroid function test and a presence of thyrotropin-receptor antibody. His weakness and hypokalemia responded well to potassium supplement and a non-selective beta blocker, while his thyrotoxicosis was initially controlled by an anti-thyroid medication and subsequently with a subtotal thyroidectomy. Clinicians should beware of this manifestation when administering steroids in the thyrotoxic patients, especially of Asian male descent.

  • a genome wide association study identifies novel susceptibility genetic variation for thyrotoxic Hypokalemic Periodic Paralysis
    Journal of Human Genetics, 2012
    Co-Authors: Wallaya Jongjaroenprasert, Thiti Snabboon, Theerawut Phusantisampan, Surakameth Mahasirimongkol, Taisei Mushiroda, Nattiya Hirankarn, Suwannee Chanprasertyotin, Puntip Tantiwong, Supamai Soonthornpun, Paninee Rattanapichart
    Abstract:

    A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic Hypokalemic Periodic Paralysis

Paninee Rattanapichart - One of the best experts on this subject based on the ideXlab platform.

S. P. Rathi - One of the best experts on this subject based on the ideXlab platform.

  • BRIEF REPORTS Primary Hypokalemic Periodic Paralysis
    2015
    Co-Authors: V. P. Dandge, W. B. Pagarkar, M. Agarwal, Vikas R. Dharnidharka, S. P. Rathi
    Abstract:

    Primary Hypokalemic Periodic Paralysis (PHPP) is a rare entity first described by Shakanowitch in 1882. Only a few cases of PHPP have been reported in Indian litera-ture in adults(l). In children Hypokalemic Paralysis secondary to gastroenteritis and chronic renal disease is much more com-mon than primary disease(2). We hereby report a case of PHPP in a child, success-fully managed with acetazolamide and oral potassium supplementation. Case Report An 11-year-old boy weighing 15 kg presented with complaints of recurrent attacks of quadriparesis since 3 years of age. Each episode used to start with sym-metrical lower limb weakness progressing to the upper limbs over a period of 3-4 hours. Spontaneous recovery occurred ove

  • Primary Hypokalemic Periodic Paralysis
    Indian pediatrics, 1994
    Co-Authors: V. P. Dandge, W. B. Pagarkar, M. Agarwal, Vikas R. Dharnidharka, S. P. Rathi
    Abstract:

    Primary Hypokalemic Periodic Paralysis (PHPP) is a rare entity first described by Shakanowitch in 1882. Only a few cases of PHPP have been reported in Indian literature in adults(l). In children Hypokalemic Paralysis secondary to gastroenteritis and chronic renal disease is much more common than primary disease(2). We hereby report a case of PHPP in a child, successfully managed with acetazolamide and oral potassium supplementation.

Serdar Guler - One of the best experts on this subject based on the ideXlab platform.

  • Thyrotoxic Hypokalemic Periodic Paralysis: A Case Report
    2014
    Co-Authors: Mazhar Muslum Tuna, Bercem Aycicek Dogan, Narin Nasiroglu Imga, Ersen Karakilic, Mine Karadeniz, Yasemin Tutuncu, Serhat Isik, Dilek Berker, Serdar Guler
    Abstract:

    Abstract Hypokalemic Periodic Paralysis is a rare disorder characterized by reversible attacks of muscle weakness accompanied by episodic hypokalemia. The most common causes of Hypokalemic Periodic Paralysis (HPP) are familial Periodic Paralysis, thyrotoxic Periodic Paralysis (TPP) and sporadic Periodic Paralysis, respectively. There are generally some precipitating factors such as stress, vigorous exercise and high carbohydrate food consumption which all ease the occurrence of attacks. The duration of attacks range from 2-36 hours and can be shortened by K+ supplementation in appropriate situations. 28 years old male, admitted to our clinic with severe weakness at his legs and arms, on laboratory examination severe hypocalemia due to overt thyrotoksicosis detected. After antithyroid drug therapy his symptoms and hypocalemia resolved. After three months of therapy he underwent total thyroidectomy because of incompliance to medical therapy. Rapid recognition and management of the disorder were the key factors to avoid fatal complications. Key Words: Hypokalemic Periodic Paralysis, thyrotoxicosis, graves disease

  • Thyrotoxic Hypokalemic Periodic Paralysis: A Case Report
    2014
    Co-Authors: Mazhar Muslum Tuna, Bercem Aycicek Dogan, Narin Nasiroglu Imga, Ersen Karakilic, Mine Karadeniz, Yasemin Tutuncu, Serhat Isik, Dilek Berker, Serdar Guler
    Abstract:

    Hypokalemic Periodic Paralysis is a rare disorder characterized by reversible attacks of muscle weakness accompanied by episodic hypokalemia. The most common causes of Hypokalemic Periodic Paralysis (HPP) are familial Periodic Paralysis, thyrotoxic Periodic Paralysis (TPP) and sporadic Periodic Paralysis, respectively. There are generally some precipitating factors such as stress, vigorous exercise and high carbohydrate food consumption which all ease the occurrence of attacks. The duration of attacks range from 2-36 hours and can be shortened by K+ supplementation in appropriate situations. 28 years old male, admitted to our clinic with severe weakness at his legs and arms, on laboratory examination severe hypocalemia due to overt thyrotoksicosis detected. After antithyroid drug therapy his symptoms and hypocalemia resolved. After three months of therapy he underwent total thyroidectomy because of incompliance to medical therapy. Rapid recognition and management of the disorder were the key factors to avoid fatal complications.

Wallaya Jongjaroenprasert - One of the best experts on this subject based on the ideXlab platform.