The Experts below are selected from a list of 93 Experts worldwide ranked by ideXlab platform
A. Dhakal - One of the best experts on this subject based on the ideXlab platform.
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Effective Treatment of Acute Otitis Externa: a Comparison of Steroid Antibiotic Versus 10% Ichthammol Glycerine Pack
Indian Journal of Otolaryngology and Head & Neck Surgery, 2010Co-Authors: B. L. Shrestha, I. Shrestha, R. C. M. Amatya, A. DhakalAbstract:To compare the efficacy of treatment between steroid–antibiotic and 10% Ichthammol glycerine packs (IG packs) in acute otitis externa. A prospective, randomized clinical trial between steroid–antibiotic and 10% IG pack which was performed in department of ENT-HNS, Kathmandu University Hospital, Dhulikhel from July 2009 to December 2009 on 82 patients. Pain was assessed by Numerical Rating Scale (NRS) and edema was assessed by dividing the external auditory canal in four quadrant giving score of 25% for each on the day of presentation and subsequent visits till tragal tenderness and edema subsided. Age group among studied patients ranged from 10 to 60 years, with mean of 23.5 years. Out of which 42 (51.2%) were females and 40 (48.8%) were males. Average number of visits in 10% IG pack group ( n = 41) was 5.4 days (2–5 visits) while in steroid–antibiotic group ( n = 41) it was 3.5 days (2–5 visits). There was statistically significant decrease in the number of visits in steroid group ( P
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effective treatment of acute otitis externa a comparison of steroid antibiotic versus 10 Ichthammol glycerine pack
Indian Journal of Otolaryngology and Head & Neck Surgery, 2010Co-Authors: B. L. Shrestha, I. Shrestha, R. C. M. Amatya, A. DhakalAbstract:To compare the efficacy of treatment between steroid–antibiotic and 10% Ichthammol glycerine packs (IG packs) in acute otitis externa. A prospective, randomized clinical trial between steroid–antibiotic and 10% IG pack which was performed in department of ENT-HNS, Kathmandu University Hospital, Dhulikhel from July 2009 to December 2009 on 82 patients. Pain was assessed by Numerical Rating Scale (NRS) and edema was assessed by dividing the external auditory canal in four quadrant giving score of 25% for each on the day of presentation and subsequent visits till tragal tenderness and edema subsided. Age group among studied patients ranged from 10 to 60 years, with mean of 23.5 years. Out of which 42 (51.2%) were females and 40 (48.8%) were males. Average number of visits in 10% IG pack group (n = 41) was 5.4 days (2–5 visits) while in steroid–antibiotic group (n = 41) it was 3.5 days (2–5 visits). There was statistically significant decrease in the number of visits in steroid group (P < 0.05). Similarly, decrease in pain score in second visit was statistically significant (P = 0.02) in steroid–antibiotic group as compared to 10% IG pack, while the edema score in second visit while comparing steroid–antibiotic group with 10% IG pack was statistically not significant (P = 0.07), whereas it was statistically highly significant on fourth visit (P = 0.001). Since the control of pain and edema is more and hence the number of visits is significantly less in steroid–antibiotic packing group, so it is worthwhile to use steroid–antibiotic pack for effective treatment of acute otitis externa.
M Kietzmann - One of the best experts on this subject based on the ideXlab platform.
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anti inflammatory antibacterial and antimycotic effects of dark sulfonated shale oil Ichthammol
Berliner Und Munchener Tierarztliche Wochenschrift, 2000Co-Authors: G Gayko, W Cholcha, M KietzmannAbstract:: Dark sulfonated shale oil (Ichthammol, ammoniumbituminosulfonate) is an active ingredient of natural origin that was included in Annex II of European Council Regulation (EEC) 2377/90. Therefore, this well-tolerated substance is available further on as a dermatological agent for the application to animals from which food is produced for human consumption. The manifold pharmacological actions could be substantiated in numerous in-vitro studies using the Ichthammol from Seefeld, Austria. The antiinflammatory action which is well-known from clinical experience could be traced back to an influence of the substance on the formation, secretion and effect of inflammation mediators. Antibacterial and antimycotic actions which are well-known from clinical use could be confirmed in in-vitro studies as well.
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Effects of Pale Ichthyol in a Model of Impaired Wound Healing
Wound Healing and Skin Physiology, 1995Co-Authors: M Kietzmann, D. Lubach, M. Swoboda, A. GeislerAbstract:Ichthyol (Ichthammol, ammonium ichthosulfonate, ichthyol ammonium, ammonium bituminosulfonate) is a reddish brown viscous fluid with a characteristic odor. It is manufactured form shale oils of high sulfur content. The oily distillate is sulfonated to form sulfonic acids and subsequently neutralized. Sulfonated shale oils are mixtures of a number of compounds. These include saturated and unsaturated hydrocarbons, including hetero-cyclic sulfur containing hydrocarbons. Dark sulfonated shale oil is a result of treatment of shale oil with sulfuric acid at higher temperature. Pale ichthyol is obtained from gentle sulfonation at lower temperature. In contrast to tar, the sulfonated shale oils are water soluble (Koch et al. 1985).
B. L. Shrestha - One of the best experts on this subject based on the ideXlab platform.
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Effective Treatment of Acute Otitis Externa: a Comparison of Steroid Antibiotic Versus 10% Ichthammol Glycerine Pack
Indian Journal of Otolaryngology and Head & Neck Surgery, 2010Co-Authors: B. L. Shrestha, I. Shrestha, R. C. M. Amatya, A. DhakalAbstract:To compare the efficacy of treatment between steroid–antibiotic and 10% Ichthammol glycerine packs (IG packs) in acute otitis externa. A prospective, randomized clinical trial between steroid–antibiotic and 10% IG pack which was performed in department of ENT-HNS, Kathmandu University Hospital, Dhulikhel from July 2009 to December 2009 on 82 patients. Pain was assessed by Numerical Rating Scale (NRS) and edema was assessed by dividing the external auditory canal in four quadrant giving score of 25% for each on the day of presentation and subsequent visits till tragal tenderness and edema subsided. Age group among studied patients ranged from 10 to 60 years, with mean of 23.5 years. Out of which 42 (51.2%) were females and 40 (48.8%) were males. Average number of visits in 10% IG pack group ( n = 41) was 5.4 days (2–5 visits) while in steroid–antibiotic group ( n = 41) it was 3.5 days (2–5 visits). There was statistically significant decrease in the number of visits in steroid group ( P
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effective treatment of acute otitis externa a comparison of steroid antibiotic versus 10 Ichthammol glycerine pack
Indian Journal of Otolaryngology and Head & Neck Surgery, 2010Co-Authors: B. L. Shrestha, I. Shrestha, R. C. M. Amatya, A. DhakalAbstract:To compare the efficacy of treatment between steroid–antibiotic and 10% Ichthammol glycerine packs (IG packs) in acute otitis externa. A prospective, randomized clinical trial between steroid–antibiotic and 10% IG pack which was performed in department of ENT-HNS, Kathmandu University Hospital, Dhulikhel from July 2009 to December 2009 on 82 patients. Pain was assessed by Numerical Rating Scale (NRS) and edema was assessed by dividing the external auditory canal in four quadrant giving score of 25% for each on the day of presentation and subsequent visits till tragal tenderness and edema subsided. Age group among studied patients ranged from 10 to 60 years, with mean of 23.5 years. Out of which 42 (51.2%) were females and 40 (48.8%) were males. Average number of visits in 10% IG pack group (n = 41) was 5.4 days (2–5 visits) while in steroid–antibiotic group (n = 41) it was 3.5 days (2–5 visits). There was statistically significant decrease in the number of visits in steroid group (P < 0.05). Similarly, decrease in pain score in second visit was statistically significant (P = 0.02) in steroid–antibiotic group as compared to 10% IG pack, while the edema score in second visit while comparing steroid–antibiotic group with 10% IG pack was statistically not significant (P = 0.07), whereas it was statistically highly significant on fourth visit (P = 0.001). Since the control of pain and edema is more and hence the number of visits is significantly less in steroid–antibiotic packing group, so it is worthwhile to use steroid–antibiotic pack for effective treatment of acute otitis externa.
Jaan Panesar - One of the best experts on this subject based on the ideXlab platform.
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A randomised controlled trial comparing Triadcortyl^® with 10% glycerine–Ichthammol in the initial treatment of severe acute otitis externa
European Archives of Oto-Rhino-Laryngology, 2008Co-Authors: Ajmal Masood, Ioannis Moumoulidis, Om Chawla, Jaan PanesarAbstract:Acute otitis externa is a common clinical condition accounting for a large proportion of patients attending the otolaryngology department, although milder cases are often managed in primary care. Treatment of the most severe forms of otitis externa involves aural toilet, followed by the application of a topical preparation, commonly in the form of an ear canal dressing. A prospective single-blind randomized controlled trial was performed to compare the efficacy of 10% glycerine–Ichthammol (GI) solution and Triadcortyl^® (TAC) ointment, both applied as ear canal dressings, in the initial management of severe acute otitis externa. A total of 64 patients were studied. Both treatment modalities were proven efficacious in the treatment of severe acute otitis externa. Although there was a statistically significant improvement of pain parameters in the TAC group, we found no significant differences in clinical findings between the two groups. Therefore, it is recommended that GI dressing can be used instead of an antibiotic dressing as an initial treatment of severe acute otitis externa on the basis of cost, avoidance of resistance and toxicity.
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a randomised controlled trial comparing triadcortyl with 10 glycerine Ichthammol in the initial treatment of severe acute otitis externa
European Archives of Oto-rhino-laryngology, 2008Co-Authors: Ajmal Masood, Ioannis Moumoulidis, Om Chawla, Jaan PanesarAbstract:Acute otitis externa is a common clinical condition accounting for a large proportion of patients attending the otolaryngology department, although milder cases are often managed in primary care. Treatment of the most severe forms of otitis externa involves aural toilet, followed by the application of a topical preparation, commonly in the form of an ear canal dressing. A prospective single-blind randomized controlled trial was performed to compare the efficacy of 10% glycerine–Ichthammol (GI) solution and Triadcortyl® (TAC) ointment, both applied as ear canal dressings, in the initial management of severe acute otitis externa. A total of 64 patients were studied. Both treatment modalities were proven efficacious in the treatment of severe acute otitis externa. Although there was a statistically significant improvement of pain parameters in the TAC group, we found no significant differences in clinical findings between the two groups. Therefore, it is recommended that GI dressing can be used instead of an antibiotic dressing as an initial treatment of severe acute otitis externa on the basis of cost, avoidance of resistance and toxicity.
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A randomised controlled trial comparing Triadcortyl with 10% glycerine-Ichthammol in the initial treatment of severe acute otitis externa.
European Archives of Oto-rhino-laryngology, 2007Co-Authors: Ajmal Masood, Ioannis Moumoulidis, Om Chawla, Jaan PanesarAbstract:Acute otitis externa is a common clinical condition accounting for a large proportion of patients attending the otolaryngology department, although milder cases are often managed in primary care. Treatment of the most severe forms of otitis externa involves aural toilet, followed by the application of a topical preparation, commonly in the form of an ear canal dressing. A prospective single-blind randomized controlled trial was performed to compare the efficacy of 10% glycerine–Ichthammol (GI) solution and Triadcortyl® (TAC) ointment, both applied as ear canal dressings, in the initial management of severe acute otitis externa. A total of 64 patients were studied. Both treatment modalities were proven efficacious in the treatment of severe acute otitis externa. Although there was a statistically significant improvement of pain parameters in the TAC group, we found no significant differences in clinical findings between the two groups. Therefore, it is recommended that GI dressing can be used instead of an antibiotic dressing as an initial treatment of severe acute otitis externa on the basis of cost, avoidance of resistance and toxicity.
Srijana Sapkota - One of the best experts on this subject based on the ideXlab platform.
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efficacy of 10 Ichthammol glycerine pack and steroid antibiotic pack for relieving pain in acute otitis externa a comparative study
Birat Journal of Health Sciences, 2019Co-Authors: Karuna Shrestha, Rajeev Shah, Srijana SapkotaAbstract:DOI: https://doi.org/10.3126/bjhs.v4i1.23937 Introduction: Otitis externa is a common painful condition presents with generalized infection of external auditory canal, typically reveals erythema and edema of the skin. Aural packing plays an important role in relieving the pain and edema. For packing, either we impregnated with 10% Ichthammol glycerine or steroid-antibiotic ointment. Objective: To compare the efficacy of 10% Ichthammol Glycerine pack with steroid-antibiotic ointment pack for relieving the pain in acute otitis externa. Methodology: A prospective, non-randomized clinical trial was carried out in 94 patients at Birat Medical College and Teaching Hospital, Biratnagar, Nepal from February 2018 to July 2018. Patients diagnosed with acute otitis externa were included in this study, where 47 patients were treated with 10% IG pack and remaining 47 patients treated with a combination steroid antibiotic ointment pack. Before aural packing was carried out, pain was assessed using visual analogue scale (VAS). Both groups of patients were evaluated after 48 hours for assessment of pain. Results: The total number of patients included in this study was 94. Among them 41 (43.6%) were male and 53(56.4%) were female where male and female ratio was 1:1.29. Majority of the patients were below 40 years (83%). Treatment with steroid-antibiotic ointment pack had significant reduction in pain after 48 hours post treatment, none of them had severe pain, 4(8.5%) had moderate pain remaining and 43(91.4%) had only mild pain. Whereas in patients treated with 10% IG pack 1(2.1%) had severe pain, 14(29.7%) had moderate pain and 32(68%) had mild pain. There was statistically significant decrease in pain with steroid-antibiotic pack. Conclusions: Both treatment modalities are effective but this study showed steroid-antibiotic ointment pack, the combined therapy is more effective than 10% IG pack for relieving the pain in acute otitis externa. Keywords: Acute otitis externa (AOE), steroid-antibiotic pack, 10% Ichthammol glycerine (IG) pack
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Efficacy of 10% Ichthammol Glycerine Pack and Steroid-antibiotic Pack for Relieving Pain in Acute Otitis Externa. A Comparative Study.
Birat Journal of Health Sciences, 2019Co-Authors: Karuna Shrestha, Rajeev Kumar Shah, Srijana SapkotaAbstract:DOI: https://doi.org/10.3126/bjhs.v4i1.23937 Introduction: Otitis externa is a common painful condition presents with generalized infection of external auditory canal, typically reveals erythema and edema of the skin. Aural packing plays an important role in relieving the pain and edema. For packing, either we impregnated with 10% Ichthammol glycerine or steroid-antibiotic ointment. Objective: To compare the efficacy of 10% Ichthammol Glycerine pack with steroid-antibiotic ointment pack for relieving the pain in acute otitis externa. Methodology: A prospective, non-randomized clinical trial was carried out in 94 patients at Birat Medical College and Teaching Hospital, Biratnagar, Nepal from February 2018 to July 2018. Patients diagnosed with acute otitis externa were included in this study, where 47 patients were treated with 10% IG pack and remaining 47 patients treated with a combination steroid antibiotic ointment pack. Before aural packing was carried out, pain was assessed using visual analogue scale (VAS). Both groups of patients were evaluated after 48 hours for assessment of pain. Results: The total number of patients included in this study was 94. Among them 41 (43.6%) were male and 53(56.4%) were female where male and female ratio was 1:1.29. Majority of the patients were below 40 years (83%). Treatment with steroid-antibiotic ointment pack had significant reduction in pain after 48 hours post treatment, none of them had severe pain, 4(8.5%) had moderate pain remaining and 43(91.4%) had only mild pain. Whereas in patients treated with 10% IG pack 1(2.1%) had severe pain, 14(29.7%) had moderate pain and 32(68%) had mild pain. There was statistically significant decrease in pain with steroid-antibiotic pack. Conclusions: Both treatment modalities are effective but this study showed steroid-antibiotic ointment pack, the combined therapy is more effective than 10% IG pack for relieving the pain in acute otitis externa. Keywords: Acute otitis externa (AOE), steroid-antibiotic pack, 10% Ichthammol glycerine (IG) pack
