Latent Trait

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Douglas A. Granger - One of the best experts on this subject based on the ideXlab platform.

  • Overestimating Self-Blame for Stressful Life Events and Adolescents' Latent Trait Cortisol: The Moderating Role of Parental Warmth.
    2019
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Blair E. Curzi, Douglas A. Granger, Leah D Doane
    Abstract:

    Cognitive interpretations of stressful events impact their implications for physiological stress processes. However, whether such interpretations are related to Trait cortisol-an indicator of individual differences in stress physiology-is unknown. In 112 early adolescent girls (M age = 12.39 years), this study examined the association between self-blame estimates for past year events and Latent Trait cortisol, and whether maternal warmth moderated effects. Overestimating self-blame (versus objective indices) for independent (uncontrollable) events was associated with lower Latent Trait cortisol, and maternal warmth moderated the effect of self-blame estimates on Latent Trait cortisol for each dependent (at least partially controllable) and interpersonal events. Implications for understanding the impact of cognitive and interpersonal factors on Trait cortisol during early adolescence are discussed.

  • individual differences in early adolescents Latent Trait cortisol interaction of early adversity and 5 httlpr
    2017
    Co-Authors: Frances R. Chen, Catherine B. Stroud, Leah D Doane, Suzanne Vrshekschallhorn, Douglas A. Granger
    Abstract:

    The present study aimed to examine the interaction of 5-HTTLPR and early adversity on Trait-like levels of cortisol. A community sample of 117 early adolescent girls (M age=12.39years) provided DNA samples for 5-HTTLPR genotyping, and saliva samples for assessing cortisol 3 times a day (waking, 30min post-waking, and bedtime) over a three-day period. Latent Trait cortisol (LTC) was modeled using the first 2 samples of each day. Early adversity was assessed with objective contextual stress interviews with adolescents and their mothers. A significant 5-HTTLPR×early adversity interaction indicated that greater early adversity was associated with lower LTC levels, but only among individuals with either L/L or S/L genotype. Findings suggest that serotonergic genetic variation may influence the impact of early adversity on individual differences in HPA-axis regulation. Future research should explore whether this interaction contributes to the development of psychopathology through HPA axis functioning.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to early adversity
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Substantial evidence suggests that youth who experience early adversity exhibit alterations in hypothalamic pituitary adrenal (HPA) axis functioning, thereby increasing risk for negative health outcomes. However, few studies have explored whether early adversity alters enduring Trait indicators of HPA axis activity. Using objective contextual stress interviews with adolescents and their mothers to assess early adversity, we examined the cumulative impact of nine types of early adversity on early adolescents girls' Latent Trait cortisol (LTC). Adolescents (n = 122; M age = 12.39 years) provided salivary cortisol samples three times a day (waking, 30 min post-waking, and bedtime) over 3 days. Latent state-Trait modeling indicated that the waking and 30 min post-waking samples contributed to a LTC factor. Moreover, greater early adversity was associated with a lower LTC level. Implications of LTC for future research examining the impact of early adversity on HPA axis functioning are discussed. © 2016 Wiley Periodicals, Inc. Dev Psychobiol 58:700-713, 2016.

  • salivary Latent Trait cortisol ltc relation to lipids blood pressure and body composition in middle childhood
    2016
    Co-Authors: Ellen W Yeung, Rebecca Place, Heather Gordishdressman, Paul S Visich, Eric P Hoffman, Sheila O Walker, Douglas A. Granger
    Abstract:

    Adversity experienced early in life has the potential to influence physical health later in life. The stress-health relation may be partially explained by stress-related effects on cardiovascular risk factors. This study explored links between individual differences in Trait-like variation in the activity of the hypothalamic-pituitary-adrenal (HPA) axis with cardiovascular risk factors in children. 474 children (M age=9.22years; 54% female; 83% Caucasian) were included in this study, in which cardiovascular risk was assessed using the following indices - triglycerides (TG), HDL-cholesterol (HDL-C), glucose (Glu); resting systolic and diastolic blood pressure, body mass index (BMI), waist-to-hip ratio, and % fat. Saliva samples were measured 3 times a day (waking, 30min post-waking and bedtime) over 3days (later assayed for cortisol). A Latent Trait cortisol (LTC) factor explained 43% of the variance in cortisol levels within and across days. Confirmatory factor analysis identified three cardiovascular risk factors: lipids (i.e., TG and HDL-C), blood pressure (i.e., systolic and diastolic), and body composition (i.e., BMI, Waist-to-hip ratio, and % fat). Lower salivary LTC was associated with higher lipids, higher blood pressure, and higher body composition. The findings further support the internal and external validity of the LTC construct, and may also advance our understanding of the link between interindividual differences in HPA axis activity and cardiovascular risk in middle childhood.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to recent acute and chronic stress
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Research suggests that environmental stress contributes to health by altering the regulation of the hypothalamic pituitary adrenal (HPA) axis. Recent evidence indicates that early life stress alters Trait indicators of HPA axis activity, but whether recent stress alters such indicators is unknown. Using objective contextual stress interviews with adolescent girls and their mothers, we examined the impact of recent acute and chronic stress occurring during the past year on early adolescent girls' Latent Trait cortisol (LTC) level. We also examined whether associations between recent stress and LTC level: a) varied according to the interpersonal nature and controllability of the stress; and b) remained after accounting for the effect of early life stress. Adolescents (n=117;M age=12.39years) provided salivary cortisol samples three times a day (waking, 30min post-waking and bedtime) over 3days. Results indicated that greater recent interpersonal acute stress and greater recent independent (i.e., uncontrollable) acute stress were each associated with a higher LTC level, over and above the effect of early adversity. In contrast, greater recent chronic stress was associated with a lower LTC level. Findings were similar in the overall sample and a subsample of participants who strictly adhered to the timed schedule of saliva sample collection. Implications for understanding the impact of recent stress on Trait-like individual differences in HPA axis activity are discussed.

Leah D Doane - One of the best experts on this subject based on the ideXlab platform.

  • Overestimating Self-Blame for Stressful Life Events and Adolescents' Latent Trait Cortisol: The Moderating Role of Parental Warmth.
    2019
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Blair E. Curzi, Douglas A. Granger, Leah D Doane
    Abstract:

    Cognitive interpretations of stressful events impact their implications for physiological stress processes. However, whether such interpretations are related to Trait cortisol-an indicator of individual differences in stress physiology-is unknown. In 112 early adolescent girls (M age = 12.39 years), this study examined the association between self-blame estimates for past year events and Latent Trait cortisol, and whether maternal warmth moderated effects. Overestimating self-blame (versus objective indices) for independent (uncontrollable) events was associated with lower Latent Trait cortisol, and maternal warmth moderated the effect of self-blame estimates on Latent Trait cortisol for each dependent (at least partially controllable) and interpersonal events. Implications for understanding the impact of cognitive and interpersonal factors on Trait cortisol during early adolescence are discussed.

  • individual differences in early adolescents Latent Trait cortisol interaction of early adversity and 5 httlpr
    2017
    Co-Authors: Frances R. Chen, Catherine B. Stroud, Leah D Doane, Suzanne Vrshekschallhorn, Douglas A. Granger
    Abstract:

    The present study aimed to examine the interaction of 5-HTTLPR and early adversity on Trait-like levels of cortisol. A community sample of 117 early adolescent girls (M age=12.39years) provided DNA samples for 5-HTTLPR genotyping, and saliva samples for assessing cortisol 3 times a day (waking, 30min post-waking, and bedtime) over a three-day period. Latent Trait cortisol (LTC) was modeled using the first 2 samples of each day. Early adversity was assessed with objective contextual stress interviews with adolescents and their mothers. A significant 5-HTTLPR×early adversity interaction indicated that greater early adversity was associated with lower LTC levels, but only among individuals with either L/L or S/L genotype. Findings suggest that serotonergic genetic variation may influence the impact of early adversity on individual differences in HPA-axis regulation. Future research should explore whether this interaction contributes to the development of psychopathology through HPA axis functioning.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to early adversity
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Substantial evidence suggests that youth who experience early adversity exhibit alterations in hypothalamic pituitary adrenal (HPA) axis functioning, thereby increasing risk for negative health outcomes. However, few studies have explored whether early adversity alters enduring Trait indicators of HPA axis activity. Using objective contextual stress interviews with adolescents and their mothers to assess early adversity, we examined the cumulative impact of nine types of early adversity on early adolescents girls' Latent Trait cortisol (LTC). Adolescents (n = 122; M age = 12.39 years) provided salivary cortisol samples three times a day (waking, 30 min post-waking, and bedtime) over 3 days. Latent state-Trait modeling indicated that the waking and 30 min post-waking samples contributed to a LTC factor. Moreover, greater early adversity was associated with a lower LTC level. Implications of LTC for future research examining the impact of early adversity on HPA axis functioning are discussed. © 2016 Wiley Periodicals, Inc. Dev Psychobiol 58:700-713, 2016.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to recent acute and chronic stress
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Research suggests that environmental stress contributes to health by altering the regulation of the hypothalamic pituitary adrenal (HPA) axis. Recent evidence indicates that early life stress alters Trait indicators of HPA axis activity, but whether recent stress alters such indicators is unknown. Using objective contextual stress interviews with adolescent girls and their mothers, we examined the impact of recent acute and chronic stress occurring during the past year on early adolescent girls' Latent Trait cortisol (LTC) level. We also examined whether associations between recent stress and LTC level: a) varied according to the interpersonal nature and controllability of the stress; and b) remained after accounting for the effect of early life stress. Adolescents (n=117;M age=12.39years) provided salivary cortisol samples three times a day (waking, 30min post-waking and bedtime) over 3days. Results indicated that greater recent interpersonal acute stress and greater recent independent (i.e., uncontrollable) acute stress were each associated with a higher LTC level, over and above the effect of early adversity. In contrast, greater recent chronic stress was associated with a lower LTC level. Findings were similar in the overall sample and a subsample of participants who strictly adhered to the timed schedule of saliva sample collection. Implications for understanding the impact of recent stress on Trait-like individual differences in HPA axis activity are discussed.

  • Latent Trait cortisol ltc levels reliability validity and stability
    2015
    Co-Authors: Leah D Doane, Frances R. Chen, Douglas A. Granger, Michael R Sladek, Scott A Van Lenten
    Abstract:

    The regulation of the hypothalamic pituitary adrenal (HPA) axis has received empirical attention as a mechanism contributing to individual differences in health and human development. A variety of sampling tactics and strategies index daily HPA axis functioning including the cortisol awakening response (CAR), the diurnal slope, and the area under the curve (AUGg). In an ethnically diverse sample (54% European-American, 23% Latino) of 82 adolescents (24% male, M age=18.05 years), we assessed salivary cortisol 45 times over the transition to college: 5 times per day, over 3 sequential days, across 3 waves (initially, 5, and 9 months later). Samples were collected at waking; 30 min, 3, and 8h post waking; and bedtime. Latent state-Trait modeling indicated that the waking and 30 min post waking samples contributed to indices of within and across wave Latent Trait cortisol (LTC) levels. As such, a Latent Trait factor of cortisol was derived to reflect both within- and across-wave Trait components of the variance in cortisol. LTC was distinct from the CAR, differentially predicted components of the diurnal profile across the day, and was highly stable across assessment waves (months). As preliminary evidence for convergent validity of LTC levels, childhood trauma was positively associated with LTC. Findings document the reliability, divergent and convergent validity, and stability of a Latent Trait factor of individual differences in HPA axis activity that may provide a cost efficient alternative to existing strategies and minimize participant burden.

Frances R. Chen - One of the best experts on this subject based on the ideXlab platform.

  • Overestimating Self-Blame for Stressful Life Events and Adolescents' Latent Trait Cortisol: The Moderating Role of Parental Warmth.
    2019
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Blair E. Curzi, Douglas A. Granger, Leah D Doane
    Abstract:

    Cognitive interpretations of stressful events impact their implications for physiological stress processes. However, whether such interpretations are related to Trait cortisol-an indicator of individual differences in stress physiology-is unknown. In 112 early adolescent girls (M age = 12.39 years), this study examined the association between self-blame estimates for past year events and Latent Trait cortisol, and whether maternal warmth moderated effects. Overestimating self-blame (versus objective indices) for independent (uncontrollable) events was associated with lower Latent Trait cortisol, and maternal warmth moderated the effect of self-blame estimates on Latent Trait cortisol for each dependent (at least partially controllable) and interpersonal events. Implications for understanding the impact of cognitive and interpersonal factors on Trait cortisol during early adolescence are discussed.

  • individual differences in early adolescents Latent Trait cortisol interaction of early adversity and 5 httlpr
    2017
    Co-Authors: Frances R. Chen, Catherine B. Stroud, Leah D Doane, Suzanne Vrshekschallhorn, Douglas A. Granger
    Abstract:

    The present study aimed to examine the interaction of 5-HTTLPR and early adversity on Trait-like levels of cortisol. A community sample of 117 early adolescent girls (M age=12.39years) provided DNA samples for 5-HTTLPR genotyping, and saliva samples for assessing cortisol 3 times a day (waking, 30min post-waking, and bedtime) over a three-day period. Latent Trait cortisol (LTC) was modeled using the first 2 samples of each day. Early adversity was assessed with objective contextual stress interviews with adolescents and their mothers. A significant 5-HTTLPR×early adversity interaction indicated that greater early adversity was associated with lower LTC levels, but only among individuals with either L/L or S/L genotype. Findings suggest that serotonergic genetic variation may influence the impact of early adversity on individual differences in HPA-axis regulation. Future research should explore whether this interaction contributes to the development of psychopathology through HPA axis functioning.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to early adversity
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Substantial evidence suggests that youth who experience early adversity exhibit alterations in hypothalamic pituitary adrenal (HPA) axis functioning, thereby increasing risk for negative health outcomes. However, few studies have explored whether early adversity alters enduring Trait indicators of HPA axis activity. Using objective contextual stress interviews with adolescents and their mothers to assess early adversity, we examined the cumulative impact of nine types of early adversity on early adolescents girls' Latent Trait cortisol (LTC). Adolescents (n = 122; M age = 12.39 years) provided salivary cortisol samples three times a day (waking, 30 min post-waking, and bedtime) over 3 days. Latent state-Trait modeling indicated that the waking and 30 min post-waking samples contributed to a LTC factor. Moreover, greater early adversity was associated with a lower LTC level. Implications of LTC for future research examining the impact of early adversity on HPA axis functioning are discussed. © 2016 Wiley Periodicals, Inc. Dev Psychobiol 58:700-713, 2016.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to recent acute and chronic stress
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Research suggests that environmental stress contributes to health by altering the regulation of the hypothalamic pituitary adrenal (HPA) axis. Recent evidence indicates that early life stress alters Trait indicators of HPA axis activity, but whether recent stress alters such indicators is unknown. Using objective contextual stress interviews with adolescent girls and their mothers, we examined the impact of recent acute and chronic stress occurring during the past year on early adolescent girls' Latent Trait cortisol (LTC) level. We also examined whether associations between recent stress and LTC level: a) varied according to the interpersonal nature and controllability of the stress; and b) remained after accounting for the effect of early life stress. Adolescents (n=117;M age=12.39years) provided salivary cortisol samples three times a day (waking, 30min post-waking and bedtime) over 3days. Results indicated that greater recent interpersonal acute stress and greater recent independent (i.e., uncontrollable) acute stress were each associated with a higher LTC level, over and above the effect of early adversity. In contrast, greater recent chronic stress was associated with a lower LTC level. Findings were similar in the overall sample and a subsample of participants who strictly adhered to the timed schedule of saliva sample collection. Implications for understanding the impact of recent stress on Trait-like individual differences in HPA axis activity are discussed.

  • Latent Trait testosterone among 18 24 year olds methodological considerations and risk associations
    2016
    Co-Authors: Frances R. Chen, Jacinda K Dariotis, Douglas A. Granger
    Abstract:

    Abstract The study investigated the relationship between Latent Trait testosterone (LTT) and risk-taking among 126 youth ( M age = 21.34 years; 56% female; 52% African American). Latent state-Trait (LST) modeling isolates observed variance of samples via their correlations into (1) a Latent Trait testosterone (LTT) factor capturing individual differences, and (2) a component of state testosterone factor (LST) capturing state-specific situational or environmental influences and random error variances. Participants provided four laboratory (20 min apart) and four home (waking, 20-min post-waking, noon, evening) salivary samples (later assayed for testosterone). Participants reported risk-taking tendencies and behaviors via an Audio Computer Assisted Self-Interview. Behavioral risk was measured using the Balloon Analog Risk Task. Results revealed: (1) LTT model invariance (operated similarly) for females and males; (2) LTT accounted for 18–89% (home samples) and 61–95% (lab samples) of the variance in testosterone levels, and (3) LTT was associated with risk-seeking behaviors and the strength of this association was similar across males and females. LST Modeling has potential to advance our understanding of testosterone-behavior associations to new limits by estimating stable Trait-like components of the variance in testosterone levels.

Catherine B. Stroud - One of the best experts on this subject based on the ideXlab platform.

  • Overestimating Self-Blame for Stressful Life Events and Adolescents' Latent Trait Cortisol: The Moderating Role of Parental Warmth.
    2019
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Blair E. Curzi, Douglas A. Granger, Leah D Doane
    Abstract:

    Cognitive interpretations of stressful events impact their implications for physiological stress processes. However, whether such interpretations are related to Trait cortisol-an indicator of individual differences in stress physiology-is unknown. In 112 early adolescent girls (M age = 12.39 years), this study examined the association between self-blame estimates for past year events and Latent Trait cortisol, and whether maternal warmth moderated effects. Overestimating self-blame (versus objective indices) for independent (uncontrollable) events was associated with lower Latent Trait cortisol, and maternal warmth moderated the effect of self-blame estimates on Latent Trait cortisol for each dependent (at least partially controllable) and interpersonal events. Implications for understanding the impact of cognitive and interpersonal factors on Trait cortisol during early adolescence are discussed.

  • individual differences in early adolescents Latent Trait cortisol interaction of early adversity and 5 httlpr
    2017
    Co-Authors: Frances R. Chen, Catherine B. Stroud, Leah D Doane, Suzanne Vrshekschallhorn, Douglas A. Granger
    Abstract:

    The present study aimed to examine the interaction of 5-HTTLPR and early adversity on Trait-like levels of cortisol. A community sample of 117 early adolescent girls (M age=12.39years) provided DNA samples for 5-HTTLPR genotyping, and saliva samples for assessing cortisol 3 times a day (waking, 30min post-waking, and bedtime) over a three-day period. Latent Trait cortisol (LTC) was modeled using the first 2 samples of each day. Early adversity was assessed with objective contextual stress interviews with adolescents and their mothers. A significant 5-HTTLPR×early adversity interaction indicated that greater early adversity was associated with lower LTC levels, but only among individuals with either L/L or S/L genotype. Findings suggest that serotonergic genetic variation may influence the impact of early adversity on individual differences in HPA-axis regulation. Future research should explore whether this interaction contributes to the development of psychopathology through HPA axis functioning.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to early adversity
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Substantial evidence suggests that youth who experience early adversity exhibit alterations in hypothalamic pituitary adrenal (HPA) axis functioning, thereby increasing risk for negative health outcomes. However, few studies have explored whether early adversity alters enduring Trait indicators of HPA axis activity. Using objective contextual stress interviews with adolescents and their mothers to assess early adversity, we examined the cumulative impact of nine types of early adversity on early adolescents girls' Latent Trait cortisol (LTC). Adolescents (n = 122; M age = 12.39 years) provided salivary cortisol samples three times a day (waking, 30 min post-waking, and bedtime) over 3 days. Latent state-Trait modeling indicated that the waking and 30 min post-waking samples contributed to a LTC factor. Moreover, greater early adversity was associated with a lower LTC level. Implications of LTC for future research examining the impact of early adversity on HPA axis functioning are discussed. © 2016 Wiley Periodicals, Inc. Dev Psychobiol 58:700-713, 2016.

  • individual differences in early adolescents Latent Trait cortisol ltc relation to recent acute and chronic stress
    2016
    Co-Authors: Catherine B. Stroud, Frances R. Chen, Leah D Doane, Douglas A. Granger
    Abstract:

    Research suggests that environmental stress contributes to health by altering the regulation of the hypothalamic pituitary adrenal (HPA) axis. Recent evidence indicates that early life stress alters Trait indicators of HPA axis activity, but whether recent stress alters such indicators is unknown. Using objective contextual stress interviews with adolescent girls and their mothers, we examined the impact of recent acute and chronic stress occurring during the past year on early adolescent girls' Latent Trait cortisol (LTC) level. We also examined whether associations between recent stress and LTC level: a) varied according to the interpersonal nature and controllability of the stress; and b) remained after accounting for the effect of early life stress. Adolescents (n=117;M age=12.39years) provided salivary cortisol samples three times a day (waking, 30min post-waking and bedtime) over 3days. Results indicated that greater recent interpersonal acute stress and greater recent independent (i.e., uncontrollable) acute stress were each associated with a higher LTC level, over and above the effect of early adversity. In contrast, greater recent chronic stress was associated with a lower LTC level. Findings were similar in the overall sample and a subsample of participants who strictly adhered to the timed schedule of saliva sample collection. Implications for understanding the impact of recent stress on Trait-like individual differences in HPA axis activity are discussed.

Michelle G Craske - One of the best experts on this subject based on the ideXlab platform.

  • prospective associations of low positive emotionality with first onsets of depressive and anxiety disorders results from a 10 wave Latent Trait state modeling study
    2015
    Co-Authors: Ashley D Kendall, Lyuba Bobova, Jason M Prenoveau, Richard E. Zinbarg, Susan Mineka, William Revelle, Michelle G Craske
    Abstract:

    Unipolar depressive disorders and anxiety disorders co-occur at high rates and can be difficult to distinguish from one another. Cross-sectional evidence has demonstrated that whereas all these disorders are characterized by high negative emotion, low positive emotion shows specificity in its associations with depressive disorders, social anxiety disorder, and possibly generalized anxiety disorder. However, it remains unknown whether low positive emotionality, a personality Trait characterized by the tendency to experience low positive emotion over time, prospectively marks risk for the initial development of these disorders. We aimed to help address this gap. Each year for up to 10 waves, participants (n = 627, mean age = 17 years at baseline) completed self-report measures of mood and personality and a structured clinical interview. A Latent Trait-state decomposition technique was used to model positive emotionality and related personality Traits over the first 3 years of the study. Survival analyses were used to test the prospective associations of low positive emotionality with first onsets of disorders over the subsequent 6-year follow-up among participants with no relevant disorder history. The results showed that low positive emotionality was a risk marker for depressive disorders, social anxiety disorder, and generalized anxiety disorder, although evidence for its specificity to these disorders versus the remaining anxiety disorders was inconclusive. Additional analyses revealed that the risk effects were largely accounted for by the overlap of low positive emotionality with neuroticism. The implications for understanding the role of positive emotionality in depressive disorders and anxiety disorders are discussed.

  • prospective associations of low positive emotionality with first onsets of depressive and anxiety disorders results from a 10 wave Latent Trait state modeling study
    2015
    Co-Authors: Ashley D Kendall, Lyuba Bobova, Jason M Prenoveau, Richard E. Zinbarg, Susan Mineka, William Revelle, Michelle G Craske
    Abstract:

    Unipolar depressive disorders and anxiety disorders co-occur at high rates and can be difficult to distinguish from one another. Cross-sectional evidence has demonstrated that whereas all these disorders are characterized by high negative emotion, low positive emotion shows specificity in its associations with depressive disorders, social anxiety disorder, and possibly generalized anxiety disorder. However, it remains unknown whether low positive emotionality, a personality Trait characterized by the tendency to experience low positive emotion over time, prospectively marks risk for the initial development of these disorders. We aimed to help address this gap. Each year for up to 10 waves, participants (n = 627, mean age = 17 years at baseline) completed self-report measures of mood and personality and a structured clinical interview. A Latent Trait-state decomposition technique was used to model positive emotionality and related personality Traits over the first 3 years of the study. Survival analyses were used to test the prospective associations of low positive emotionality with first onsets of disorders over the subsequent 6-year follow-up among participants with no relevant disorder history. The results showed that low positive emotionality was a risk marker for depressive disorders, social anxiety disorder, and generalized anxiety disorder, although evidence for its specificity to these disorders versus the remaining anxiety disorders was inconclusive. Additional analyses revealed that the risk effects were largely accounted for by the overlap of low positive emotionality with neuroticism. The implications for understanding the role of positive emotionality in depressive disorders and anxiety disorders are discussed.