The Experts below are selected from a list of 123201 Experts worldwide ranked by ideXlab platform

Nicolas Bourmeyster - One of the best experts on this subject based on the ideXlab platform.

  • Gap junctional channels are parts of multiprotein complexes
    Biochimica et Biophysica Acta, 2011
    Co-Authors: Jean-claude Hervé, Mickaël Derangeon, Denis Sarrouilhe, Ben N. G. Giepmans, Nicolas Bourmeyster
    Abstract:

    Gap junctional channels are a class of membrane channels composed of transmembrane channel-forming integral membrane proteins termed connexins, innexins or pannexins that mediate direct cell-to-cell or cell-to extracellular Medium Communication in almost all animal tissues. The activity of these channels is tightly regulated, particularly by intramolecular modifications as phosphorylations of proteins and via the formation of multiprotein complexes where pore-forming subunits bind to auxiliary channel subunits and associate with scaffolding proteins that play essential roles in channel localization and activity. Scaffolding proteins link signaling enzymes, substrates, and potential effectors (such as channels) into multiprotein signaling complexes that may be anchored to the cytoskeleton. Protein-protein interactions play essential roles in channel localization and activity and, besides their cell-to-cell channel-forming functions, gap junctional proteins now appear involved in different cellular functions (e.g. transcriptional and cytoskeletal regulations). The present review summarizes the recent progress regarding the proteins capable of interacting with junctional proteins and highlights the function of these protein-protein interactions in cell physiology and aberrant function in diseases. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and functions. (C) 2011 Elsevier B.V. All rights reserved.

  • Gap junctional channels are parts of multiprotein complexes
    Biochimica et biophysica acta, 2011
    Co-Authors: Jean-claude Hervé, Mickaël Derangeon, Denis Sarrouilhe, Ben N. G. Giepmans, Nicolas Bourmeyster
    Abstract:

    Gap junctional channels are a class of membrane channels composed of transmembrane channel-forming integral membrane proteins termed connexins, innexins or pannexins that mediate direct cell-to-cell or cell-to extracellular Medium Communication in almost all animal tissues. The activity of these channels is tightly regulated, particularly by intramolecular modifications as phosphorylations of proteins and via the formation of multiprotein complexes where pore-forming subunits bind to auxiliary channel subunits and associate with scaffolding proteins that play essential roles in channel localization and activity. Scaffolding proteins link signaling enzymes, substrates, and potential effectors (such as channels) into multiprotein signaling complexes that may be anchored to the cytoskeleton. Protein-protein interactions play essential roles in channel localization and activity and, besides their cell-to-cell channel-forming functions, gap junctional proteins now appear involved in different cellular functions (e.g. transcriptional and cytoskeletal regulations). The present review summarizes the recent progress regarding the proteins capable of interacting with junctional proteins and highlights the function of these protein-protein interactions in cell physiology and aberrant function in diseases. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and functions.

Hongke Zhang - One of the best experts on this subject based on the ideXlab platform.

  • An ontology and peer-to-peer based data and service unified discovery system
    Expert Systems with Applications, 2009
    Co-Authors: Ying Zhang, Houkuan Huang, Dong Yang, Hongke Zhang
    Abstract:

    The next generation Internet has the potential ability to be a ubiquitous and pervasive Medium Communication carrier for all types of information. The World Wide Web is emerging with a broader variety of resources that include both data and services. Yet, a lot of research work focused on either service discovery or data discovery although they cannot be separated from each other. In addition, the current Network, due to its decentralized nature and weak support for semantic, is still chaotic and lacks of the ability to allow users to discover, extract and integrate information of interest from heterogeneous sources. In this paper, we present a scalable, high performance system for data and service unified discovery, and to increase the success rate, an ontology-based approach is used to describe data and services. As for service, we add quality of service (QoS) information to OWL-S files to get more accurate results for users. Moreover, we also bring JXTA, which is a suitable foundation to build future computer systems on, to our system.

Alberto Rabbachin - One of the best experts on this subject based on the ideXlab platform.

  • Distributed Network Secrecy
    IEEE Journal on Selected Areas in Communications, 2013
    Co-Authors: Alberto Rabbachin
    Abstract:

    Secrecy is essential for a variety of emerging wireless applications where distributed confidential information is communicated in a multilevel network from sources to destinations. Network secrecy can be accomplished by exploiting the intrinsic properties of multilevel wireless networks (MWN). This paper introduces the concept of distributed network secrecy (DNS) and develops a framework for the design and analysis of secure, reliable, and efficient MWNs. Our framework accounts for node spatial distribution, multilevel cluster formation, propagation Medium, Communication protocol, and energy consumption. This research provides a foundation for DNS and offers a new perspective on the relationship between DNS and network lifetime.

Klaus Werner Schmidt - One of the best experts on this subject based on the ideXlab platform.

  • SIU - The verification of a novel framework for real-time shared Medium Communication network protocols
    2012 20th Signal Processing and Communications Applications Conference (SIU), 2012
    Co-Authors: Yusuf Bora Kartal, Ece Guran Schmidt, Klaus Werner Schmidt
    Abstract:

    The subject of this work is the real-time Communication of the distributed industrial control applications over shared-Medium Ethernet. We developed a framework for the real-time Communication protocols over shared-Medium Ethernet in our previous work. The framework is designed using the Timed Input/Output Automata formalism to serve the changing real-time Communication needs of the embedded control applications. In this paper we present the modeling, simulation and formal verification process of the proposed framework using UPPAAL toolbox.

  • Shared Medium Communication for distributed discrete event control
    2008 IEEE 16th Signal Processing Communication and Applications Conference, 2008
    Co-Authors: Ece Guran Schmidt, Klaus Werner Schmidt
    Abstract:

    The synthesis of efficient distributed discrete-event controllers that are potentially implemented in networked controller devices has been extensively studied in recent years. However, different from the controller synthesis, the realization of such controllers on a network requires the additional consideration of timing issues due to the Communication. To this end, we present a Communication model including real-time requirements for the operation of distributed discrete-event controllers. Furthermore, we propose a deterministic real-time Communication operation of the distributed controllers according to this Communication model, and state a sufficient condition for the network bandwidth such that the formulated real-time requirements are satisfied. Our operation is evaluated with a simulation study and compared to the nondeterministic behavior of the standard Ethernet.

  • A shared-Medium Communication architecture for distributed discrete event systems
    2007 Mediterranean Conference on Control & Automation, 2007
    Co-Authors: Klaus Werner Schmidt, Ece Guran Schmidt, J. Zaddach
    Abstract:

    Recently, several efficient supervisor synthesis approaches for distributed discrete event systems (DES) have been established. In this paper, the implementation of such supervisors on interacting distributed programmable logic controllers (PLCs) on a network is considered for the hierarchical and decentralized control approach elaborated in our previous work. A Communication model that captures the controller behavior relevant for Communication is developed, and a network architecture together with a scheduling policy that ensures correct operation of the networked controllers is proposed. In addition to the formal statements, simulation results for an example system are presented.

Jean-claude Hervé - One of the best experts on this subject based on the ideXlab platform.

  • Gap junctional channels are parts of multiprotein complexes
    Biochimica et Biophysica Acta, 2011
    Co-Authors: Jean-claude Hervé, Mickaël Derangeon, Denis Sarrouilhe, Ben N. G. Giepmans, Nicolas Bourmeyster
    Abstract:

    Gap junctional channels are a class of membrane channels composed of transmembrane channel-forming integral membrane proteins termed connexins, innexins or pannexins that mediate direct cell-to-cell or cell-to extracellular Medium Communication in almost all animal tissues. The activity of these channels is tightly regulated, particularly by intramolecular modifications as phosphorylations of proteins and via the formation of multiprotein complexes where pore-forming subunits bind to auxiliary channel subunits and associate with scaffolding proteins that play essential roles in channel localization and activity. Scaffolding proteins link signaling enzymes, substrates, and potential effectors (such as channels) into multiprotein signaling complexes that may be anchored to the cytoskeleton. Protein-protein interactions play essential roles in channel localization and activity and, besides their cell-to-cell channel-forming functions, gap junctional proteins now appear involved in different cellular functions (e.g. transcriptional and cytoskeletal regulations). The present review summarizes the recent progress regarding the proteins capable of interacting with junctional proteins and highlights the function of these protein-protein interactions in cell physiology and aberrant function in diseases. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and functions. (C) 2011 Elsevier B.V. All rights reserved.

  • Gap junctional channels are parts of multiprotein complexes
    Biochimica et biophysica acta, 2011
    Co-Authors: Jean-claude Hervé, Mickaël Derangeon, Denis Sarrouilhe, Ben N. G. Giepmans, Nicolas Bourmeyster
    Abstract:

    Gap junctional channels are a class of membrane channels composed of transmembrane channel-forming integral membrane proteins termed connexins, innexins or pannexins that mediate direct cell-to-cell or cell-to extracellular Medium Communication in almost all animal tissues. The activity of these channels is tightly regulated, particularly by intramolecular modifications as phosphorylations of proteins and via the formation of multiprotein complexes where pore-forming subunits bind to auxiliary channel subunits and associate with scaffolding proteins that play essential roles in channel localization and activity. Scaffolding proteins link signaling enzymes, substrates, and potential effectors (such as channels) into multiprotein signaling complexes that may be anchored to the cytoskeleton. Protein-protein interactions play essential roles in channel localization and activity and, besides their cell-to-cell channel-forming functions, gap junctional proteins now appear involved in different cellular functions (e.g. transcriptional and cytoskeletal regulations). The present review summarizes the recent progress regarding the proteins capable of interacting with junctional proteins and highlights the function of these protein-protein interactions in cell physiology and aberrant function in diseases. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and functions.