The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
François Bonhomme - One of the best experts on this subject based on the ideXlab platform.
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HASSAN RAJABI-MAHAM3, HON-TSEN YU4, SYLVIE AGRET1,
2016Co-Authors: Roohollah Siahsarvie, François Bonhomme, Jeanchristophe Auffray, Jamshid Darvish, Julien ClaudeAbstract:The worldwide distributed house mouse, Mus Musculus, is subdivided into at least three lineages, Mus Musculus Musculus, Mus Musculus domesticus, and Mus Musculus Castaneus. The subspecies occur parapatrically in a region considered to be the cradle of the species in Southern Asia (‘central region’), as well as in the rest of the world (‘peripheral region’). The morphological evolution of this species in a phylogeographical context is studied using a landmark-based approach on mandible morphology of different populations of the three lineages. The morphological variation increases from central to peripheral regions at the population and subspecific levels, confirming a centrifugal sub-speciation within this species. Furthermore, the outgroup comparison with sister species suggests that M. Musculus Musculus and populations of all subspecies inhabiting the Iranian plateau have retained a more ancestral mandible morphology, suggesting that this region may represent one of the relevant places of the origin of the species. Mus Musculus Castaneus, both from central and peripheral regions, is morphologically the most variable and divergent subspecies. Finally, the results obtained in the present study suggest that the independent evolution to commensalism in the three lineages is not accompanied by a convergence detectable on jaw morphology. © 201
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Mus Musculus Castaneus
Brenner's Encyclopedia of Genetics, 2013Co-Authors: François Bonhomme, Annie OrthAbstract:The House Mouse Mus Musculus is now seen as a polytypic species where three main branches have differentiated in isolation within the past 500 000 years and have come to contact again on several occasions. It is almost invariably considered as being constituted of three subspecies, Mus Musculus Castaneus being considered as more polymorphic, with a larger effective population size and as having retained more ancestral polymorphisms than the other two. Yet, it is the less, well-studied component, and its geographical origin and genetic makeup disserve more careful attention since a recent reappraisal was indeed shown that the House Mouse populations in the region ranging from Middle-East to Southeast Asia classically assigned to M. m. Castaneus are indeed much more diverse than previously thought. Since the House Mouse is often taken as a model species, this may have important bearings on our understanding of the context in which genome evolution and speciation occurs.
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The south-eastern house mouse Mus Musculus Castaneus (Rodentia: Muridae) is a polytypic subspecies
Biological Journal of the Linnean Society, 2012Co-Authors: Hassan Rajabi-maham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically wellcharacterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies.
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the south eastern house mouse Mus Musculus Castaneus rodentia muridae is a polytypic subspecies
Biological Journal of The Linnean Society, 2012Co-Authors: Hassan Rajabimaham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically well-characterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, ••, ••–••.
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The south‐eastern house mouse Mus Musculus Castaneus (Rodentia: Muridae) is a polytypic subspecies
Biological Journal of the Linnean Society, 2012Co-Authors: Hassan Rajabi-maham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically well-characterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, ••, ••–••.
Akira Ishikawa - One of the best experts on this subject based on the ideXlab platform.
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Genetic identification of Ly75 as a novel quantitative trait gene for resistance to obesity in mice
Scientific reports, 2018Co-Authors: Keita Makino, Akira IshikawaAbstract:Identification of causal quantitative trait genes (QTGs) governing obesity is challenging. We previously revealed that the lymphocyte antigen 75 (Ly75) gene with an immune function is a putative QTG for Pbwg1.5, a quantitative trait locus (QTL) for resistance to obesity found from wild mice (Mus Musculus Castaneus). The objective of this study was to identify a true QTG for Pbwg1.5 by a combined approach of a quantitative complementation test, qualitative phenotypic analyses and causal analysis using segregating populations. In a four-way cross population among an Ly75 knockout strain, a subcongenic strain carrying Pbwg1.5 and their background strains, the quantitative complementation test showed genetic evidence that the Ly75 locus is identical to Pbwg1.5. Qualitative phenotypic analyses in two intercross populations between knockout and background strains and between subcongenic and background strains suggested that Ly75 may have pleiotropic effects on weights of white fat pads and organs. Causal analysis in the intercross population between knockout and background strains revealed that only variation in fat pad weight is caused by the genotypic difference via the difference in liver Ly75 expression. The results showed that Ly75 is a true Pbwg1.5 QTG for resistance to obesity. The finding provides a novel insight for obesity biology.
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Relative introgressed genomic interval of the B6.Cg-Pbwg1/1Nga subcongenic strain (abbreviation SR1).
2017Co-Authors: Akira IshikawaAbstract:B6.Cg-Pbwg1/1Nga was developed from the original B6.Cg-Pbwg1 congenic strain carrying the Pbwg1 growth QTL on mouse chromosome 2. The black bar shows the minimum introgressed interval derived from the wild Mus Musculus Castaneus mouse. The genomic region of the black bar in B6.Cg-Pbwg1 was previously exome-sequenced [16]. The black-bar region of SR1 was RNA-sequenced in this study. The gray bar shows the interval derived from the C57BL/6JJcl (B6) background strain. The hatched bar indicates the interval where recombination occurred. The map positions (Mb) of microsatellite markers (D2Mit#) and PCR-RFLP markers (rs#) previously developed [16] are shown on the horizontal line. The horizontal double-headed arrows indicate the maximum intervals of body weight and body composition QTLs (Pbwg1.#) previously defined [16]. The effect of the QTL allele derived from the wild Castaneus mouse is shown together with the QTL name. The filled triangle indicates the map position of Ly75, a strong candidate gene for Pbwg1.5. WAT, white adipose tissue.
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Diversity and complexity of the mouse Saa1 and Saa2 genes.
Experimental animals, 2014Co-Authors: Masayuki Mori, Akira Ishikawa, Geng Tian, Keiichi HiguchiAbstract:Mouse strains show polymorphisms in the amino acid sequences of serum amyloid A 1 (SAA1) and serum amyloid A 2 (SAA2). Major laboratory mouse strains are classified based on the sequence as carrying the A haplotype (e.g., BALB/c) or B haplotype (e.g., SJL/J) of the Saa1 and Saa2 gene unit. We attempted to elucidate the diversity of the mouse Saa1 and Saa2 family genes at the nucleotide sequence level by a systematic survey of 6 inbred mouse strains from 4 Mus subspecies, including Mus Musculus domesticus, Mus Musculus Musculus, Mus Musculus Castaneus, and Mus spretus. Saa1 and Saa2 genes were obtained from the mouse genome by PCR amplification, and each full-length nucleotide sequence was determined. We found that Mus Musculus Castaneus mice uniquely possess 2 divergent Saa1 genes linked on chromosome 7. Overall, the mouse strains had distinct composite patterns of amino acid substitutions at 9 positions in SAA1 and SAA2 isoforms. The mouse strains also had distinct composite patterns of 2 polymorphic upstream regulatory elements that influenced gene transcription in in vitro reporter assays. B haplotype mice were revealed to possess an LTR insertion in the downstream region of Saa1. Collectively, these results indicate that the mouse Saa genes hold broader diversity and greater complexity than previously known, and these characteristics were likely attained through gene duplication and repeated gene conversion events in the Mus lineage.
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Relative introgressed genomic intervals of four subcongenic strains (B6.Cg-Pbwg1/#Nga, abbreviation SR#) developed from the original B6.Cg-Pbwg1 congenic strain carrying the Pbwg1 growth QTL on mouse chromosome 2.
2014Co-Authors: Akira Ishikawa, Sin-ichiro OkunoAbstract:The black bar indicates the minimum introgressed interval derived from the wild Mus Musculus Castaneus mouse, and the gray bar indicates the interval from the background C57BL/6JJcl (B6) strain. The hatched bar shows a gray zone where recombination occurred. The physical map positions (Mb) of 27 microsatellite markers (D2Mit#) and two PCR-RFLP markers (rs#) developed in this study (Figure S1) are shown on the horizontal line. The triangle indicates the position of the peak LOD score for three body composition QTLs (Pbwg1.3 to Pbwg1.5) previously identified [19], [21]. The horizontal double-headed arrows indicate the maximum intervals of two body weight QTLs (Pbwg1.11 and Pbwg1.12) previously defined [9].
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Genetic and Molecular Analysis of Wild-Derived Arrhythmic Mice
2013Co-Authors: Tsuyoshi Watanabe, Akira Ishikawa, Tohru Suzuki, Yuki Yokota, Hiroki R. Ueda, Rikuhiro G, Hajime Tei, Saki Imai, Shigeru Tomida, Junya KobayashiAbstract:A new circadian variant was isolated by screening the intercross offspring of wild-caught mice (Mus Musculus Castaneus). This variant was characterized by an initial maintenance of damped oscillations and subsequent loss of rhythmicity after being transferred from light-dark (LD) cycles to constant darkness (DD). To map the genes responsible for the persistence of rhythmicity (circadian ratio) and the length of free-running period (t), quantitative trait locus (QTL) analysis was performed using F2 mice obtained from an F1 cross between the circadian variant and C57BL/6J mice. As a result, a significant QTL with a main effect for circadian ratio (Arrhythmicity; Arrh-1) was mapped on Chromosome (Chr) 8. For t, four significant QTLs
Roohollah Siahsarvie - One of the best experts on this subject based on the ideXlab platform.
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HASSAN RAJABI-MAHAM3, HON-TSEN YU4, SYLVIE AGRET1,
2016Co-Authors: Roohollah Siahsarvie, François Bonhomme, Jeanchristophe Auffray, Jamshid Darvish, Julien ClaudeAbstract:The worldwide distributed house mouse, Mus Musculus, is subdivided into at least three lineages, Mus Musculus Musculus, Mus Musculus domesticus, and Mus Musculus Castaneus. The subspecies occur parapatrically in a region considered to be the cradle of the species in Southern Asia (‘central region’), as well as in the rest of the world (‘peripheral region’). The morphological evolution of this species in a phylogeographical context is studied using a landmark-based approach on mandible morphology of different populations of the three lineages. The morphological variation increases from central to peripheral regions at the population and subspecific levels, confirming a centrifugal sub-speciation within this species. Furthermore, the outgroup comparison with sister species suggests that M. Musculus Musculus and populations of all subspecies inhabiting the Iranian plateau have retained a more ancestral mandible morphology, suggesting that this region may represent one of the relevant places of the origin of the species. Mus Musculus Castaneus, both from central and peripheral regions, is morphologically the most variable and divergent subspecies. Finally, the results obtained in the present study suggest that the independent evolution to commensalism in the three lineages is not accompanied by a convergence detectable on jaw morphology. © 201
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the south eastern house mouse Mus Musculus Castaneus rodentia muridae is a polytypic subspecies
Biological Journal of The Linnean Society, 2012Co-Authors: Hassan Rajabimaham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically well-characterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, ••, ••–••.
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The south-eastern house mouse Mus Musculus Castaneus (Rodentia: Muridae) is a polytypic subspecies
Biological Journal of the Linnean Society, 2012Co-Authors: Hassan Rajabi-maham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically wellcharacterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies.
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The south‐eastern house mouse Mus Musculus Castaneus (Rodentia: Muridae) is a polytypic subspecies
Biological Journal of the Linnean Society, 2012Co-Authors: Hassan Rajabi-maham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically well-characterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, ••, ••–••.
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patterns of morphological evolution in the mandible of the house mouse Mus Musculus rodentia muridae
Biological Journal of The Linnean Society, 2012Co-Authors: François Bonhomme, Roohollah Siahsarvie, Jeanchristophe Auffray, Jamshid Darvish, Hassan Rajabimaham, Sylvie Agret, Julien ClaudeAbstract:The worldwide distributed house mouse, Mus Musculus, is subdivided into at least three lineages, Mus Musculus Musculus, Mus Musculus domesticus, and Mus Musculus Castaneus. The subspecies occur parapatrically in a region considered to be the cradle of the species in Southern Asia (‘central region’), as well as in the rest of the world (‘peripheral region’). The morphological evolution of this species in a phylogeographical context is studied using a landmark-based approach on mandible morphology of different populations of the three lineages. The morphological variation increases from central to peripheral regions at the population and subspecific levels, confirming a centrifugal sub-speciation within this species. Furthermore, the outgroup comparison with sister species suggests that M. Musculus Musculus and populations of all subspecies inhabiting the Iranian plateau have retained a more ancestral mandible morphology, suggesting that this region may represent one of the relevant places of the origin of the species. Mus Musculus Castaneus, both from central and peripheral regions, is morphologically the most variable and divergent subspecies. Finally, the results obtained in the present study suggest that the independent evolution to commensalism in the three lineages is not accompanied by a convergence detectable on jaw morphology. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, 105, 635–647.
Stuart Rudikoff - One of the best experts on this subject based on the ideXlab platform.
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Characterization of a V_ϰ family in Mus Musculus Castaneus: expansion at the subset level
Immunogenetics, 1993Co-Authors: Terry J. Henderson, Stuart RudikoffAbstract:We have examined the same kappa chain variable ( Vϰ ) region family in several mouse species in order to observe short-term, incremental change at immunoglobun ( Ig ) multigene loci. In the present study, the Igk-V24 family has been characterized in a Mus m. Castaneus colony derived from individuals originating in Thailand and compared to the same family in Mus m. domesticus (BALB/c) and Mus pahari , representing about 1 – 2 and about 5 – 9 million years of evolution, respectively. Southern hybridization of genomic DNA with a probe encoding the prototype Igk-V24 coding region reveals restriction fragment patterns indicative of two distinct M. m. Castaneus haplotypes. These haplotypes appear to result from an unequal recombination between similar gene arrays, as their restriction patterns are unique but contain many common fragments. The complexity of these patterns indicates a marked expansion in the Igk-V24 family of M. m. Castaneus relative to BALB/c and M. pahari . Additional analyses using probes specific for individual subsets demonstate that the expansion is not general throughout the entire family, but is restricted to particular subsets and therefore to relatively short chromosomal segments. One subset alone accounts for most of the expansion and comprises over 40% of the entire M. m. Castaneus family. The wide range of Igk-V24 family complexity seen among M. m. Castaneus, M. m. domesticus , and M. pahari , as well as among the different M. m. Castaneus family subsets, suggests a model of random evolution in V_ϰ family copy number rather than one which is selective.
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Characterization of a V _κ family in Mus Musculus Castaneus: sequence analysis
Immunogenetics, 1993Co-Authors: Terry J. Henderson, Stuart RudikoffAbstract:To examine genetic variation at immunoglobulin ( Ig ) multigene loci over short spans of evolutionary time, we have compared members of an Ig kappa chain variable ( V _κ) region family from several mouse species. In this study, seven unique Igk-V24 family members have been isolated from Mus m. Castaneus and characterized by nucleotide sequence determination for comparison to their counterparts in Mus m domesticus (BALB/c), and Mus pahari , representing 1–2 million years of evolution in the former case and 5–8 million years in the latter. Parsimony, together with evolutionary distances calculated for various paris of Igk-V24 family coding regions, relate all family members to a common progenitor existing roughly 24 million years ago (Mya). A significant portion of the M. m. Castaneus family consists of pseudogene segments in various degrees of progressive degeneration. The substitution patterns and divergence rates for all gene segments are characteristic of their respective subsets, especially in the areas flanking the coding regions. Complex and variable patterns of diversity are seen in potentially expressed coding regions, which appear to reflect quite different selective pressures on various subregions within the V _κ protein domain. These results indicate that evolutionary pressures are operating at the level of family subsets, their individual members, and subregions within similar molecules.
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Characterization of a Vκ family in Mus Musculus Castaneus: sequence analysis
Immunogenetics, 1993Co-Authors: Terry J. Henderson, Stuart RudikoffAbstract:To examine genetic variation at immunoglobulin (Ig) multigene loci over short spans of evolutionary time, we have compared members of an Ig kappa chain variable (Vκ) region family from several mouse species. In this study, seven unique Igk-V24 family members have been isolated from Mus m. Castaneus and characterized by nucleotide sequence determination for comparison to their counterparts in Mus m domesticus (BALB/c), and Mus pahari, representing 1–2 million years of evolution in the former case and 5–8 million years in the latter. Parsimony, together with evolutionary distances calculated for various paris of Igk-V24 family coding regions, relate all family members to a common progenitor existing roughly 24 million years ago (Mya). A significant portion of the M. m. Castaneus family consists of pseudogene segments in various degrees of progressive degeneration. The substitution patterns and divergence rates for all gene segments are characteristic of their respective subsets, especially in the areas flanking the coding regions. Complex and variable patterns of diversity are seen in potentially expressed coding regions, which appear to reflect quite different selective pressures on various subregions within the Vκ protein domain. These results indicate that evolutionary pressures are operating at the level of family subsets, their individual members, and subregions within similar molecules.
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Characterization of a Vϰ family in Mus Musculus Castaneus: expansion at the subset level
Immunogenetics, 1993Co-Authors: Terry J. Henderson, Stuart RudikoffAbstract:We have examined the same kappa chain variable (Vϰ) region family in several mouse species in order to observe short-term, incremental change at immunoglobun (Ig) multigene loci. In the present study, the Igk-V24 family has been characterized in a Mus m. Castaneus colony derived from individuals originating in Thailand and compared to the same family in Mus m. domesticus (BALB/c) and Mus pahari, representing about 1 – 2 and about 5 – 9 million years of evolution, respectively. Southern hybridization of genomic DNA with a probe encoding the prototype Igk-V24 coding region reveals restriction fragment patterns indicative of two distinct M. m. Castaneus haplotypes. These haplotypes appear to result from an unequal recombination between similar gene arrays, as their restriction patterns are unique but contain many common fragments. The complexity of these patterns indicates a marked expansion in the Igk-V24 family of M. m. Castaneus relative to BALB/c and M. pahari. Additional analyses using probes specific for individual subsets demonstate that the expansion is not general throughout the entire family, but is restricted to particular subsets and therefore to relatively short chromosomal segments. One subset alone accounts for most of the expansion and comprises over 40% of the entire M. m. Castaneus family. The wide range of Igk-V24 family complexity seen among M. m. Castaneus, M. m. domesticus, and M. pahari, as well as among the different M. m. Castaneus family subsets, suggests a model of random evolution in Vϰ family copy number rather than one which is selective.
Jamshid Darvish - One of the best experts on this subject based on the ideXlab platform.
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HASSAN RAJABI-MAHAM3, HON-TSEN YU4, SYLVIE AGRET1,
2016Co-Authors: Roohollah Siahsarvie, François Bonhomme, Jeanchristophe Auffray, Jamshid Darvish, Julien ClaudeAbstract:The worldwide distributed house mouse, Mus Musculus, is subdivided into at least three lineages, Mus Musculus Musculus, Mus Musculus domesticus, and Mus Musculus Castaneus. The subspecies occur parapatrically in a region considered to be the cradle of the species in Southern Asia (‘central region’), as well as in the rest of the world (‘peripheral region’). The morphological evolution of this species in a phylogeographical context is studied using a landmark-based approach on mandible morphology of different populations of the three lineages. The morphological variation increases from central to peripheral regions at the population and subspecific levels, confirming a centrifugal sub-speciation within this species. Furthermore, the outgroup comparison with sister species suggests that M. Musculus Musculus and populations of all subspecies inhabiting the Iranian plateau have retained a more ancestral mandible morphology, suggesting that this region may represent one of the relevant places of the origin of the species. Mus Musculus Castaneus, both from central and peripheral regions, is morphologically the most variable and divergent subspecies. Finally, the results obtained in the present study suggest that the independent evolution to commensalism in the three lineages is not accompanied by a convergence detectable on jaw morphology. © 201
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the south eastern house mouse Mus Musculus Castaneus rodentia muridae is a polytypic subspecies
Biological Journal of The Linnean Society, 2012Co-Authors: Hassan Rajabimaham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically well-characterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, ••, ••–••.
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The south-eastern house mouse Mus Musculus Castaneus (Rodentia: Muridae) is a polytypic subspecies
Biological Journal of the Linnean Society, 2012Co-Authors: Hassan Rajabi-maham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically wellcharacterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies.
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The south‐eastern house mouse Mus Musculus Castaneus (Rodentia: Muridae) is a polytypic subspecies
Biological Journal of the Linnean Society, 2012Co-Authors: Hassan Rajabi-maham, Annie Orth, Pierre Boursot, Roohollah Siahsarvie, Jamshid Darvish, François BonhommeAbstract:Accurate knowledge of the biogeographic history and precise characterization of the genetic make-up of a taxon are essential to investigate speciation processes and achieve sound evolutionary comparisons. A case in point is the house mouse Mus Musculus and its three parapatric subspecies, which have become a model for such studies. However, although Mus Musculus domesticus and Mus Musculus Musculus constitute genetically well-characterized homogeneous entities, the case of Mus Musculus Castaneus remains poorly documented. Using mtDNA control region variation in a sample of 402 individuals, covering much of the distribution range of this subspecies, we identify four haplogroups that show largely non-overlapping geographic distributions. They appear to have undergone post-Neolithic expansions, presumably through commensalism with humans, but exhibit a much more ancient divergence. These results point towards a strong past subdivision and a vicariant origin of the different haplogroups, with each retaining a subfraction of the total variability. The genomic consequences of this spatial heterogeneity on the present taxonomic partition will have to be appraised, and may challenge the use of this subspecies as a single entity in evolutionary studies. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, ••, ••–••.
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patterns of morphological evolution in the mandible of the house mouse Mus Musculus rodentia muridae
Biological Journal of The Linnean Society, 2012Co-Authors: François Bonhomme, Roohollah Siahsarvie, Jeanchristophe Auffray, Jamshid Darvish, Hassan Rajabimaham, Sylvie Agret, Julien ClaudeAbstract:The worldwide distributed house mouse, Mus Musculus, is subdivided into at least three lineages, Mus Musculus Musculus, Mus Musculus domesticus, and Mus Musculus Castaneus. The subspecies occur parapatrically in a region considered to be the cradle of the species in Southern Asia (‘central region’), as well as in the rest of the world (‘peripheral region’). The morphological evolution of this species in a phylogeographical context is studied using a landmark-based approach on mandible morphology of different populations of the three lineages. The morphological variation increases from central to peripheral regions at the population and subspecific levels, confirming a centrifugal sub-speciation within this species. Furthermore, the outgroup comparison with sister species suggests that M. Musculus Musculus and populations of all subspecies inhabiting the Iranian plateau have retained a more ancestral mandible morphology, suggesting that this region may represent one of the relevant places of the origin of the species. Mus Musculus Castaneus, both from central and peripheral regions, is morphologically the most variable and divergent subspecies. Finally, the results obtained in the present study suggest that the independent evolution to commensalism in the three lineages is not accompanied by a convergence detectable on jaw morphology. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, 105, 635–647.
