The Experts below are selected from a list of 327 Experts worldwide ranked by ideXlab platform
Kingo Chida - One of the best experts on this subject based on the ideXlab platform.
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efficacy of clarithromycin and ethambutol for Mycobacterium Avium Complex pulmonary disease a preliminary study
Annals of the American Thoracic Society, 2014Co-Authors: Seiichi Miwa, Masahiro Shirai, Kazumasa Yasuda, Masafumi Masuda, Mikio Toyoshima, Toshihiro Shirai, Naoki Inui, Koshi Yokomura, Takashi Yamada, Kingo ChidaAbstract:Rationale: Patients with Mycobacterium Avium Complex pulmonary disease are frequently administered a combination of clarithromycin, ethambutol, and rifampicin. However, rifampicin is known to reduce the serum levels of clarithromycin. It remains unclear whether a reduction in clarithromycin serum levels influences the clinical outcome of the Mycobacterium Avium Complex pulmonary disease treatment regimen.Objectives: To compare a three-drug regimen (clarithromycin, ethambutol, and rifampicin) to a two-drug regimen (clarithromycin and ethambutol) for the treatment of Mycobacterium Avium lung disease.Methods: In a preliminary open-label study, we randomly assigned newly diagnosed, but as-yet untreated, patients with disease caused by Mycobacterium Avium Complex without HIV infection to either the three-drug or the two-drug regimen for 12 months. The primary endpoint was the conversion of sputum cultures to negative after 12 months of treatment. Patient data were analyzed using the intention-to-treat method.M...
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Mycobacterium Avium Complex disease: prognostic implication of high-resolution computed tomography findings.
The European respiratory journal, 2008Co-Authors: Shigeki Kuroishi, Masahiro Shirai, Kazumasa Yasuda, Yutaro Nakamura, Hiroshi Hayakawa, Y. Nakano, Takafumi Suda, Hidenori Nakamura, Kingo ChidaAbstract:To evaluate the prognostic implications of computed tomography (CT) findings in assessing responses to treatment in Mycobacterium Avium Complex (MAC) pulmonary disease without underlying lung disease, high-resolution (HR)CT findings were correlated based on the results of sputum conversion after anti-MAC therapy. A total of 59 patients underwent HRCT before treatment and the therapeutic efficacy was evaluated by the results of sputum conversion. Atelectasis, cavities and pleural thickening on HRCT were significantly more frequent and extensive among patients in the sputum nonconverted group than among those in the converted group. Furthermore, bronchiectasis was also significantly more extensive among patients in the nonconverted group, even though there was no significant difference in frequency between these two groups. These results suggest that high-resolution computed tomography findings are good predictors of response to treatment in Mycobacterium Avium Complex pulmonary disease.
Gerard A. Cangelosi - One of the best experts on this subject based on the ideXlab platform.
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Association between Mycobacterium Avium Complex Pulmonary Disease and Mycobacteria in Home Water and Soil.
Annals of the American Thoracic Society, 2020Co-Authors: Connie L. Tzou, M. Ashworth Dirac, Annie L. Becker, Nicola K. Beck, Kris M. Weigel, John Scott Meschke, Gerard A. CangelosiAbstract:Rationale: Nontuberculous mycobacteria (NTM), including Mycobacterium Avium Complex (MAC), are emerging pathogens that can opportunistically cause debilitating pulmonary disease in susceptible huma...
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Inactivation of Mycobacterium Avium Complex by UV irradiation.
Applied and environmental microbiology, 2008Co-Authors: Gwy Am Shin, Jung Keun Lee, Robert Freeman, Gerard A. CangelosiAbstract:The effectiveness of two major UV technologies against a highly prevalent species of Mycobacterium Avium Complex was investigated. Our study indicates that M. Avium is much more resistant to UV irradiation than most waterborne pathogens and that it is one of the rare microorganisms that are highly resistant to both chemical and UV disinfection in water.
Powel Kazanjian - One of the best experts on this subject based on the ideXlab platform.
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Mycobacterium Avium Complex immune reconstitution inflammatory syndrome: Long term outcomes
Journal of translational medicine, 2007Co-Authors: James Riddell, Daniel R. Kaul, Petros C. Karakousis, Joel E. Gallant, Jennifer A. Mitty, Powel KazanjianAbstract:Background To describe long term outcomes of Mycobacterium Avium Complex (MAC) immune reconstitution inflammatory syndrome (IRIS).
Karim Bakri - One of the best experts on this subject based on the ideXlab platform.
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Tenosynovitis Due to Mycobacterium Avium Complex.
The New England journal of medicine, 2019Co-Authors: Lucas Kreutz-rodrigues, Karim BakriAbstract:Tenosynovitis Due to Mycobacterium Avium Complex A 51-year-old right-handed man presented with swelling in the left wrist. MRI showed rice bodies and culture confirmed invasive mycobacterial tenosy...
Sarah K. Brode - One of the best experts on this subject based on the ideXlab platform.
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Clinical efficacy and safety of fluoroquinolone containing regimens in patients with Mycobacterium Avium Complex pulmonary disease.
The European respiratory journal, 2020Co-Authors: Hadeel Khadawardi, Theodore K. Marras, Mahtab Mehrabi, Sarah K. BrodeAbstract:Fluoroquinolone containing regimens for Mycobacterium Avium Complex pulmonary disease demonstrated similar treatment outcomes, but more adverse events, than standard triple therapyhttp://bit.ly/2RdlFpa
