The Experts below are selected from a list of 18828 Experts worldwide ranked by ideXlab platform
Jaap Oosterlaan - One of the best experts on this subject based on the ideXlab platform.
-
effects of timing and intensity of Neurorehabilitation on functional outcome after traumatic brain injury a systematic review and meta analysis
Archives of Physical Medicine and Rehabilitation, 2018Co-Authors: Marsh Konigs, Eva Beurskens, Lian Snoep, Erik J A Scherder, Jaap OosterlaanAbstract:Abstract Objective To systematically review evidence on the effects of timing and intensity of Neurorehabilitation on the functional recovery of patients with moderate to severe traumatic brain injury (TBI) and aggregate the available evidence using meta-analytic methods. Data Sources PubMed, Embase, PsycINFO, and Cochrane Database. Study Selection Electronic databases were searched for prospective controlled clinical trials assessing the effect of timing or intensity of multidisciplinary Neurorehabilitation programs on functional outcome of patients with moderate or severe TBI. A total of 5961 unique records were screened for relevance, of which 58 full-text articles were assessed for eligibility by 2 independent authors. Eleven articles were included for systematic review and meta-analysis. Data Extraction Two independent authors performed data extraction and risk of bias analysis using the Cochrane Collaboration tool. Discrepancies between authors were resolved by consensus. Data Synthesis Systematic review of a total of 6 randomized controlled trials, 1 quasi-randomized trial, and 4 controlled trials revealed consistent evidence for a beneficial effect of early onset Neurorehabilitation in the trauma center and intensive Neurorehabilitation in the rehabilitation facility on functional outcome compared with usual care. Meta-analytic quantification revealed a large-sized positive effect for early onset rehabilitation programs ( d =1.02; P d =.67; P Conclusions The available evidence indicates that early onset Neurorehabilitation in the trauma center and more intensive Neurorehabilitation in the rehabilitation facility promote functional recovery of patients with moderate to severe TBI compared with usual care. These findings support the integration of early onset and more intensive Neurorehabilitation in the chain of care for patients with TBI.
Emanuele Maria Giusti - One of the best experts on this subject based on the ideXlab platform.
-
The role of gender, psycho-social factors and anthropological-cultural dimensions on pain in Neurorehabilitation. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.
European journal of physical and rehabilitation medicine, 2016Co-Authors: Anna Maria Aloisi, Vanna Berlincioni, Riccardo Torta, Rossella E. Nappi, Cristina Tassorelli, Francesco Barale, Valentina Ieraci, Emanuele Maria Giusti, Giada Pietrabissa, Stefano TamburinAbstract:Pain is frequent in patients undergoing Neurorehabilitation, but there is a number of still unanswered questions on this topic. The Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was constituted with the purpose to identify the best practices that can be used in this context. In this article we summarize the existing evidence and recommendations provided by the ICCPN about the role of gender, psycho-social factors and anthropological-cultural dimensions on pain in Neurorehabilitation. Sex, gender, psycho-social variables, anthropological and cultural features may influence pain expression, and its pharmacological and non-pharmacological outcome, but the role of these factors has not been consistently explored in Neurorehabilitation. There is a number of psychological factors that can be correlated with or represent a predictor for pain, or may influence the treatment and outcome of Neurorehabilitation programs. All these factors should be considered when designing these programs, and future studies should incorporate them as potential covariates that may influence outcome.
-
Pharmacological and non-pharmacological strategies in the integrated treatment of pain in Neurorehabilitation. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.
European journal of physical and rehabilitation medicine, 2016Co-Authors: Stefano Tamburin, Stefano Paolucci, Marco Lacerenza, Gianluca Castelnuovo, Michela Agostini, Michelangelo Bartolo, Sara Bonazza, Angela Federico, Fabio Formaglio, Emanuele Maria GiustiAbstract:The interplay between pain and Neurorehabilitation is very complex, in that pain may be a target for treatment, but can also have negative effects on Neurorehabilitation procedures. Moreover, side effects of drugs, which are currently used to treat pain, may negatively influence rehabilitation outcomes. Because of the lack of guidelines or consensus, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was aimed to answer some open questions on the treatment of pain in this setting. To this aim, we collected evidence on the pharmacological and non-pharmacological strategies and their role in the integrated approach to pain. Despite the lack of studies in patients undergoing Neurorehabilitation, current guidelines on the pharmacological treatment of nociceptive and neuropathic pain may be applied in this setting. Non-pharmacological strategies include physical therapy, invasive procedures, psychological treatments and psychotherapy, which together with pharmacological therapies play a key role in the integrated approach to pain. The ICCPN recommendations offer information to ameliorate the current treatment of pain in Neurorehabilitation, and to design future studies to answer the still open questions on this topic.
Stefano Tamburin - One of the best experts on this subject based on the ideXlab platform.
-
The role of gender, psycho-social factors and anthropological-cultural dimensions on pain in Neurorehabilitation. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.
European journal of physical and rehabilitation medicine, 2016Co-Authors: Anna Maria Aloisi, Vanna Berlincioni, Riccardo Torta, Rossella E. Nappi, Cristina Tassorelli, Francesco Barale, Valentina Ieraci, Emanuele Maria Giusti, Giada Pietrabissa, Stefano TamburinAbstract:Pain is frequent in patients undergoing Neurorehabilitation, but there is a number of still unanswered questions on this topic. The Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was constituted with the purpose to identify the best practices that can be used in this context. In this article we summarize the existing evidence and recommendations provided by the ICCPN about the role of gender, psycho-social factors and anthropological-cultural dimensions on pain in Neurorehabilitation. Sex, gender, psycho-social variables, anthropological and cultural features may influence pain expression, and its pharmacological and non-pharmacological outcome, but the role of these factors has not been consistently explored in Neurorehabilitation. There is a number of psychological factors that can be correlated with or represent a predictor for pain, or may influence the treatment and outcome of Neurorehabilitation programs. All these factors should be considered when designing these programs, and future studies should incorporate them as potential covariates that may influence outcome.
-
Pharmacological and non-pharmacological strategies in the integrated treatment of pain in Neurorehabilitation. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.
European journal of physical and rehabilitation medicine, 2016Co-Authors: Stefano Tamburin, Stefano Paolucci, Marco Lacerenza, Gianluca Castelnuovo, Michela Agostini, Michelangelo Bartolo, Sara Bonazza, Angela Federico, Fabio Formaglio, Emanuele Maria GiustiAbstract:The interplay between pain and Neurorehabilitation is very complex, in that pain may be a target for treatment, but can also have negative effects on Neurorehabilitation procedures. Moreover, side effects of drugs, which are currently used to treat pain, may negatively influence rehabilitation outcomes. Because of the lack of guidelines or consensus, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was aimed to answer some open questions on the treatment of pain in this setting. To this aim, we collected evidence on the pharmacological and non-pharmacological strategies and their role in the integrated approach to pain. Despite the lack of studies in patients undergoing Neurorehabilitation, current guidelines on the pharmacological treatment of nociceptive and neuropathic pain may be applied in this setting. Non-pharmacological strategies include physical therapy, invasive procedures, psychological treatments and psychotherapy, which together with pharmacological therapies play a key role in the integrated approach to pain. The ICCPN recommendations offer information to ameliorate the current treatment of pain in Neurorehabilitation, and to design future studies to answer the still open questions on this topic.
-
The Italian Consensus Conference on Pain in Neurorehabilitation: rationale and methodology
Journal of pain research, 2016Co-Authors: Stefano Tamburin, Stefano Paolucci, Francesca Magrinelli, Massimo Musicco, Giorgio SandriniAbstract:Pain is very common in the Neurorehabilitation setting, where it may not only represent a target for treatment but can also negatively influence rehabilitation procedures directly or through the side effects of painkillers. To date, there are neither guidelines nor consensus on how to assess and treat pain in Neurorehabilitation. Because of the very scanty pieces of evi- dence on this topic, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was promoted under the auspices of different scientific societies. This article illustrates the rationale, methodology, and topics of the ICCPN. The recommendations of the ICCPN will offer some information on how to deal with pain in Neurorehabilitation and may represent the starting point for further studies.
Stefano Paolucci - One of the best experts on this subject based on the ideXlab platform.
-
Adipokines as Potential Biomarkers in the Neurorehabilitation of Obese Stroke Patients.
Current neurovascular research, 2020Co-Authors: Irene Ciancarelli, Giovanni Morone, Marco Iosa, Stefano Paolucci, Loris Pignolo, Paolo Tonin, Antonio Cerasa, Maria Giuliana Tozzi CiancarelliAbstract:Background Limited studies concern the influence of obesity-induced dysregulation of adipokines in functional recovery after stroke Neurorehabilitation. Objective To investigate the relationship between serum leptin, resistin, and adiponectin and functional recovery before and after Neurorehabilitation of obese stroke patients. The adipokine potential significance as prognostic markers of rehabilitation outcomes was also verified. Methods Twenty obese post-acute stroke patients before and after Neurorehabilitation and thirteen obese volunteers without-stroke, as controls, were examined. Adipokines were determined by commercially available enzyme-linked immunosorbent assay (ELISA) kits. Functional deficits were assessed before and after Neurorehabilitation with the Barthel Index (BI), modified Rankin Scale (mRS), and Functional Independence Measure (FIM). Results Compared to controls, higher leptin and resistin values and lower adiponectin values were observed in stroke patients before Neurorehabilitation and no correlations were found between adipokines and clinical outcome measures. Neurorehabilitation was associated with improved scores of BI, mRS, and FIM. After Neurorehabilitation, decreased values of Body Mass Index (BMI) and resistin together increased adiponectin were detected in stroke patients, while leptin decreased but not statistically. Comparing adipokine values assessed before Neurorehabilitation with the outcome measures after Neurorehabilitation, correlations were observed for leptin with BI-score, mRS-score, and FIM-score. No other adipokine levels nor BMI assessed before Neurorehabilitation correlated with the clinical measures after Neurorehabilitation. The forward stepwise regression analysis identified leptin as prognostic factor for BI, mRS, and FIM. Conclusions Our data show the effectiveness of Neurorehabilitation in modulating adipokines levels and suggest that leptin could assume the significance of biomarker of functional recovery.
-
Pharmacological and non-pharmacological strategies in the integrated treatment of pain in Neurorehabilitation. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation.
European journal of physical and rehabilitation medicine, 2016Co-Authors: Stefano Tamburin, Stefano Paolucci, Marco Lacerenza, Gianluca Castelnuovo, Michela Agostini, Michelangelo Bartolo, Sara Bonazza, Angela Federico, Fabio Formaglio, Emanuele Maria GiustiAbstract:The interplay between pain and Neurorehabilitation is very complex, in that pain may be a target for treatment, but can also have negative effects on Neurorehabilitation procedures. Moreover, side effects of drugs, which are currently used to treat pain, may negatively influence rehabilitation outcomes. Because of the lack of guidelines or consensus, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was aimed to answer some open questions on the treatment of pain in this setting. To this aim, we collected evidence on the pharmacological and non-pharmacological strategies and their role in the integrated approach to pain. Despite the lack of studies in patients undergoing Neurorehabilitation, current guidelines on the pharmacological treatment of nociceptive and neuropathic pain may be applied in this setting. Non-pharmacological strategies include physical therapy, invasive procedures, psychological treatments and psychotherapy, which together with pharmacological therapies play a key role in the integrated approach to pain. The ICCPN recommendations offer information to ameliorate the current treatment of pain in Neurorehabilitation, and to design future studies to answer the still open questions on this topic.
-
The Italian Consensus Conference on Pain in Neurorehabilitation: rationale and methodology
Journal of pain research, 2016Co-Authors: Stefano Tamburin, Stefano Paolucci, Francesca Magrinelli, Massimo Musicco, Giorgio SandriniAbstract:Pain is very common in the Neurorehabilitation setting, where it may not only represent a target for treatment but can also negatively influence rehabilitation procedures directly or through the side effects of painkillers. To date, there are neither guidelines nor consensus on how to assess and treat pain in Neurorehabilitation. Because of the very scanty pieces of evi- dence on this topic, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was promoted under the auspices of different scientific societies. This article illustrates the rationale, methodology, and topics of the ICCPN. The recommendations of the ICCPN will offer some information on how to deal with pain in Neurorehabilitation and may represent the starting point for further studies.
-
The Three Laws of Neurorobotics: A Review on What Neurorehabilitation Robots Should Do for Patients and Clinicians
Journal of Medical and Biological Engineering, 2016Co-Authors: Marco Iosa, Giovanni Morone, Andrea Cherubini, Stefano PaolucciAbstract:Most studies and reviews on robots for Neurorehabilitation focus on their effectiveness. These studies often report inconsistent results. This and many other reasons limit the credit given to these robots by therapists and patients. Further, Neurorehabilitation is often still based on therapists’ expertise, with competition among different schools of thought, generating substantial uncertainty about what exactly a Neurorehabilitation robot should do. Little attention has been given to ethics. This review adopts a new approach, inspired by Asimov’s three laws of robotics and based on the most recent studies in neurorobotics, for proposing new guidelines for designing and using robots for Neurorehabilitation. We propose three laws of neurorobotics based on the ethical need for safe and effective robots, the redefinition of their role as therapist helpers, and the need for clear and transparent human–machine interfaces. These laws may allow engineers and clinicians to work closely together on a new generation of neurorobots.
Emilia Mikołajewska - One of the best experts on this subject based on the ideXlab platform.
-
Clinical Significance of Computational Brain Models in Neurorehabilitation
Medical and Biological Sciences, 2014Co-Authors: Emilia Mikołajewska, Dariusz MikołajewskiAbstract:Despite quick development of the newest Neurorehabilitation methods and techniques there is a need for experimentally validated models of motor learning, neural control of movements, functional recovery, therapy control strategies. Computational models are perceived as another way for optimization and objectivization of the Neurorehabilitation. Fully understanding of the neural repair is needed for simulation of reorganization and remodeling of neural networks as the effect of Neurorehabilitation. Better understanding can significantly influence both traditional forms of the therapy (neurosurgery, drug therapy, Neurorehabilitation, etc.) and use of the advanced Assitive Technology (AT) solutions, e.g. brain-computer interfaces (BCIs) and neuroprostheses [49, 50] or artificial brain stimulation.
-
Robot-mediated pediatric Neurorehabilitation
Journal of Health Science, 2014Co-Authors: Emilia Mikołajewska, Dariusz Mikołajewski, Tomasz Komendziński, Joanna Dreszer-drogorób, Bibianna BałajAbstract:The huge complexity and variety of deficits in children, their continuous development, and co-operation simultaneously with children and their parents make clinical practice in pediatric Neurorehabilitation particularly challenging. Thus scientists and clinicians still look for newer, more efficient diagnostic and therapeutic tools. One of them is robot-mediated pediatric Neurorehabilitation. However, the amount of research in the area of robot-mediated pediatric Neurorehabilitation is still limited, and its impact on clinical practice seems to be underscored. The aim of this study was threefold: to establish the current state of robot-mediated pediatric Neurorehabilitation, investigate the extent to which the available opportunities in robot-mediated pediatric Neurorehabilitation are being exploited, and discuss clinical perspectives and directions for further research.
-
The prospects of brain — computer interface applications in children
Open Medicine, 2014Co-Authors: Emilia Mikołajewska, Dariusz MikołajewskiAbstract:The restoring of motor functions in adults through brain-computer interface applications is widely studied in the contemporary literature. But there is a lack of similar analyses and research on the application of brain-computer interfaces in the Neurorehabilitation of children. There is a need for expanded knowledge in the aforementioned area. This article aims at investigating the extent to which the available opportunities in the area of Neurorehabilitation and neurological physiotherapy of children with severe neurological deficits using brain-computer interfaces are being applied, including our own concepts, research and observations.
-
Eclectic approach as the natural way of development in Neurorehabilitation of adults
International Journal on Disability and Human Development, 2013Co-Authors: Emilia MikołajewskaAbstract:AbstractThe time course of recovery from neurologic disorders varies significantly depending on the severity of impairment, therapeutic measures during recovery, and patient characteristics, and no particular method can be perceived as more predominant over others. Traditional Neurorehabilitation based on specific intervention techniques can be complemented by an eclectic approach that is based on the stable principles of the methods, is open to development, and can be used in conjunction with the elements of various methods. An eclectic approach in Neurorehabilitation has the potential for a greater impact on the impairment because it can be tailored to the individual’s needs, can better predict the outcomes in individual patients with neurologic disorders, is better supported by experienced physiotherapists, and is expected to lead to progress in interdisciplinary therapy and care. The easy deployment of rehabilitation strategies and their applicability across a wide range of motor impairment make the eclectic approach an attractive and efficient solution. Its limitations are measurement reliability (especially inter-rater reliability) and validity, timing of rehabilitation, and the capacity to deliver high-intensity training protocols. The eclectic approach can be an important and useful strategy in Neurorehabilitation, and this article discusses the advantages and limitations of current traditional and eclectic Neurorehabilitation paradigms and suggest possible research directions.
