The Experts below are selected from a list of 31131 Experts worldwide ranked by ideXlab platform
Mathew Mercuri - One of the best experts on this subject based on the ideXlab platform.
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opportunities for improvement on current Nuclear Cardiology practices and radiation exposure in latin america findings from the 65 country iaea Nuclear Cardiology protocols cross sectional study incaps
Journal of Nuclear Cardiology, 2017Co-Authors: João V. Vitola, Thomas N. B. Pascual, Mathew Mercuri, Nathan Better, Ganesan Karthikeyan, Fernando Mut, Erick Alexanderson, Madan M Rehani, Ravi Kashyap, Maurizio DondiAbstract:Background Comparison of Latin American (LA) Nuclear Cardiology (NC) practice with that in the rest of the world (RoW) will identify areas for improvement and lead to educational activities to reduce radiation exposure from NC.
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WORLDWIDE VARIATION IN THE USE OF Nuclear Cardiology CAMERA TECHNOLOGY, RECONSTRUCTION SOFTWARE, AND ACQUISITION PROTOCOLS: FINDINGS FROM THE IAEA Nuclear Cardiology PROTOCOLS STUDY (INCAPS)
Journal of the American College of Cardiology, 2017Co-Authors: Edward A. Hulten, Mathew Mercuri, Maurizio Dondi, Thomas N. Pascual, João V. Vitola, Nathan Better, Ganesan Karthikeyan, John J. Mahmarian, Madan Rehani, Diana PaezAbstract:Background: Although increasing attention has been drawn to medical radiation exposure, little is reported about worldwide variation in Nuclear myocardial perfusion imaging (MPI) techniques that may result in differences in radiation exposure. The IAEA Nuclear Cardiology Protocols Study (INCAPS) was
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Nuclear Cardiology practice and associated radiation doses in Europe: results of the IAEA Nuclear Cardiology Protocols Study (INCAPS) for the 27 European countries
European Journal of Nuclear Medicine and Molecular Imaging, 2016Co-Authors: Oliver Lindner, Juhani Knuuti, Anastasia Kitsiou, Mathew Mercuri, Wanda Acampa, Wolfgang Burchert, Albert Flotats, Thomas Pascual, Philipp Kaufmann, S. Richard UnderwoodAbstract:PURPOSE: Nuclear Cardiology is widely used to diagnose coronary artery disease and to guide patient management, but data on current practices, radiation dose-related best practices, and radiation doses are scarce. To address these issues, the IAEA conducted a worldwide study of Nuclear Cardiology practice. We present the European subanalysis. METHODS: In March 2013, the IAEA invited laboratories across the world to document all SPECT and PET studies performed in one week. The data included age, gender, weight, radiopharmaceuticals, injected activities, camera type, positioning, hardware and software. Radiation effective dose was calculated for each patient. A quality score was defined for each laboratory as the number followed of eight predefined best practices with a bearing on radiation exposure (range of quality score 0 - 8). The participating European countries were assigned to regions (North, East, South, and West). Comparisons were performed between the four European regions and between Europe and the rest-of-the-world (RoW). RESULTS: Data on 2,381 European patients undergoing Nuclear Cardiology procedures in 102 laboratories in 27 countries were collected. A cardiac SPECT study was performed in 97.9 % of the patients, and a PET study in 2.1 %. The average effective dose of SPECT was 8.0 ± 3.4 mSv (RoW 11.4 ± 4.3 mSv; P
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Nuclear Cardiology practice and associated radiation doses in Europe: results of the IAEA Nuclear Cardiology Protocols Study (INCAPS) for the 27 European countries.
European Journal of Nuclear Medicine and Molecular Imaging, 2015Co-Authors: Oliver Lindner, Juhani Knuuti, Anastasia Kitsiou, Thomas N. B. Pascual, Mathew Mercuri, Wanda Acampa, Wolfgang Burchert, Albert Flotats, Philipp A. Kaufmann, S. Richard UnderwoodAbstract:Purpose Nuclear Cardiology is widely used to diagnose coronary artery disease and to guide patient management, but data on current practices, radiation dose-related best practices, and radiation doses are scarce. To address these issues, the IAEA conducted a worldwide study of Nuclear Cardiology practice. We present the European subanalysis.
João V. Vitola - One of the best experts on this subject based on the ideXlab platform.
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opportunities for improvement on current Nuclear Cardiology practices and radiation exposure in latin america findings from the 65 country iaea Nuclear Cardiology protocols cross sectional study incaps
Journal of Nuclear Cardiology, 2017Co-Authors: João V. Vitola, Thomas N. B. Pascual, Mathew Mercuri, Nathan Better, Ganesan Karthikeyan, Fernando Mut, Erick Alexanderson, Madan M Rehani, Ravi Kashyap, Maurizio DondiAbstract:Background Comparison of Latin American (LA) Nuclear Cardiology (NC) practice with that in the rest of the world (RoW) will identify areas for improvement and lead to educational activities to reduce radiation exposure from NC.
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WORLDWIDE VARIATION IN THE USE OF Nuclear Cardiology CAMERA TECHNOLOGY, RECONSTRUCTION SOFTWARE, AND ACQUISITION PROTOCOLS: FINDINGS FROM THE IAEA Nuclear Cardiology PROTOCOLS STUDY (INCAPS)
Journal of the American College of Cardiology, 2017Co-Authors: Edward A. Hulten, Mathew Mercuri, Maurizio Dondi, Thomas N. Pascual, João V. Vitola, Nathan Better, Ganesan Karthikeyan, John J. Mahmarian, Madan Rehani, Diana PaezAbstract:Background: Although increasing attention has been drawn to medical radiation exposure, little is reported about worldwide variation in Nuclear myocardial perfusion imaging (MPI) techniques that may result in differences in radiation exposure. The IAEA Nuclear Cardiology Protocols Study (INCAPS) was
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gender differences in radiation dose from Nuclear Cardiology studies across the world findings from the incaps registry
Jacc-cardiovascular Imaging, 2016Co-Authors: Lynn Shi, Diana Paez, Thomas N. B. Pascual, Leslee J. Shaw, João V. Vitola, Nathan Better, Ganesan Karthikeyan, Sharmila Dorbala, Katherine Zukotynski, Nadia BokhariAbstract:Abstract Objectives The aim of this study was to investigate gender-based differences in Nuclear Cardiology practice globally, with a particular focus on laboratory volume, radiation dose, protocols, and best practices. Background It is unclear whether gender-based differences exist in radiation exposure for Nuclear Cardiology procedures. Methods In a large, multicenter, observational, cross-sectional study encompassing 7,911 patients in 65 countries, radiation effective dose was estimated for each examination. Patient-level best practices relating to radiation exposure were compared between genders. Analysis of covariance was used to determine any difference in radiation exposure according to gender, region, and the interaction between gender and region. Linear, logistic, and hierarchical regression models were developed to evaluate gender-based differences in radiation exposure and laboratory adherence to best practices. The study also included the United Nations Gender Inequality Index and Human Development Index as covariates in multivariable models. Results The proportion of myocardial perfusion imaging studies performed in women varied among countries; however, there was no significant correlation with the Gender Inequality Index. Globally, mean effective dose for Nuclear Cardiology procedures was only slightly lower in women (9.6 ± 4.5 mSv) than in men (10.3 ± 4.5 mSv; p Conclusions Despite significant worldwide variation in best practice use and radiation doses from Nuclear Cardiology procedures, only small differences were observed between genders worldwide. Regional variations noted in myocardial perfusion imaging use and radiation dose offer potential opportunities to address gender-related differences in delivery of Nuclear Cardiology care.
Piotr J. Slomka - One of the best experts on this subject based on the ideXlab platform.
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Leveraging latest computer science tools to advance Nuclear Cardiology.
Journal of Nuclear Cardiology, 2019Co-Authors: Piotr J. SlomkaAbstract:Nuclear Cardiology has unique advantages compared to other modalities, since the image analysis is already much more automated compared to what is currently clinically performed for CT, MR, or echocardiography imaging. The diverse image and clinical data available to assess coronary disease function, perfusion, flow, and associated CT data provide new opportunities, but logistically these additional assessments increase the overall complexity of SPECT/PET reporting, necessitating additional expertise and time. The advances in artificial intelligence software can be leveraged to obtain comprehensive risk predictions and diagnoses from all available data. They will allow Nuclear Cardiology to retain competitive edge compared to other modalities and improve its overall clinical utility. These tools will enhance diagnosis and risk prediction beyond what is possible by subjective visual analysis and mental integration of data by physicians.
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New Trends in Quantitative Nuclear Cardiology Methods.
Current Cardiovascular Imaging Reports, 2018Co-Authors: Javier Gómez, Rami Doukky, Guido Germano, Piotr J. SlomkaAbstract:Purpose of review: The use of quantitative analysis in single photon emission computed tomography (SPECT) and positron emission tomography (PET) has become an integral part of current clinical practice and plays a crucial role in the detection and risk stratification of coronary artery disease. Emerging technologies, new protocols, and new quantification methods have had a significant impact on the diagnostic performance and prognostic value of Nuclear Cardiology imaging, while reducing the need for clinician oversight. In this review, we aim to describe recent advances in automation and quantitative analysis in Nuclear Cardiology. Recent Findings: Recent publications have shown that fully automatic processing is feasible, limiting human input to specific cases where aberrancies are detected by the quality control software. Furthermore, there is evidence indicating that fully quantitative analysis of myocardial perfusion imaging is feasible and can achieve at least similar diagnostic accuracy as visual interpretation by an expert clinician. In addition, the use of fully automated quantification in combination with machine learning algorithms can provide incremental diagnostic and prognostic value over the traditional method of expert visual interpretation. Summary: Emerging technologies in Nuclear Cardiology focus on automation and the use of artificial intelligence as part of the interpretation process. This review highlights the benefits and limitations of these applications, and outlines future directions in the field.
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New Trends in Quantitative Nuclear Cardiology Methods.
Current Cardiovascular Imaging Reports, 2018Co-Authors: Javier Gómez, Rami Doukky, Guido Germano, Piotr J. SlomkaAbstract:The use of quantitative analysis in single photon emission computed tomography (SPECT) and positron emission tomography (PET) has become an integral part of current clinical practice and plays a crucial role in the detection and risk stratification of coronary artery disease. Emerging technologies, new protocols, and new quantification methods have had a significant impact on the diagnostic performance and prognostic value of Nuclear Cardiology imaging while reducing the need for clinician oversight. In this review, we aim to describe recent advances in automation and quantitative analysis in Nuclear Cardiology. Recent publications have shown that fully automatic processing is feasible, limiting human input to specific cases where aberrancies are detected by the quality control software. Furthermore, there is evidence indicating that fully quantitative analysis of myocardial perfusion imaging is feasible and can achieve at least similar diagnostic accuracy as visual interpretation by an expert clinician. In addition, the use of fully automated quantification in combination with machine learning algorithms can provide incremental diagnostic and prognostic value over the traditional method of expert visual interpretation. Emerging technologies in Nuclear Cardiology focus on automation and the use of artificial intelligence as part of the interpretation process. This review highlights the benefits and limitations of these applications and outlines future directions in the field.
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automated quantitative Nuclear Cardiology methods
Cardiology Clinics, 2016Co-Authors: Manish Motwani, Guido Germano, Piotr J. Slomka, Daniel S. BermanAbstract:Quantitative analysis of SPECT and PET has become a major part of Nuclear Cardiology practice. Current software tools can automatically segment the left ventricle, quantify function, establish myocardial perfusion maps, and estimate global and local measures of stress/rest perfusion, all with minimal user input. State-of-the-art automated techniques have been shown to offer high diagnostic accuracy for detecting coronary artery disease, as well as predict prognostic outcomes. This article briefly reviews these techniques, highlights several challenges, and discusses the latest developments.
S. Richard Underwood - One of the best experts on this subject based on the ideXlab platform.
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Nuclear Cardiology practice and associated radiation doses in Europe: results of the IAEA Nuclear Cardiology Protocols Study (INCAPS) for the 27 European countries
European Journal of Nuclear Medicine and Molecular Imaging, 2016Co-Authors: Oliver Lindner, Juhani Knuuti, Anastasia Kitsiou, Mathew Mercuri, Wanda Acampa, Wolfgang Burchert, Albert Flotats, Thomas Pascual, Philipp Kaufmann, S. Richard UnderwoodAbstract:PURPOSE: Nuclear Cardiology is widely used to diagnose coronary artery disease and to guide patient management, but data on current practices, radiation dose-related best practices, and radiation doses are scarce. To address these issues, the IAEA conducted a worldwide study of Nuclear Cardiology practice. We present the European subanalysis. METHODS: In March 2013, the IAEA invited laboratories across the world to document all SPECT and PET studies performed in one week. The data included age, gender, weight, radiopharmaceuticals, injected activities, camera type, positioning, hardware and software. Radiation effective dose was calculated for each patient. A quality score was defined for each laboratory as the number followed of eight predefined best practices with a bearing on radiation exposure (range of quality score 0 - 8). The participating European countries were assigned to regions (North, East, South, and West). Comparisons were performed between the four European regions and between Europe and the rest-of-the-world (RoW). RESULTS: Data on 2,381 European patients undergoing Nuclear Cardiology procedures in 102 laboratories in 27 countries were collected. A cardiac SPECT study was performed in 97.9 % of the patients, and a PET study in 2.1 %. The average effective dose of SPECT was 8.0 ± 3.4 mSv (RoW 11.4 ± 4.3 mSv; P
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A History of Nuclear Cardiology in the UK
A History of Radionuclide Studies in the UK, 2016Co-Authors: S. Richard UnderwoodAbstract:The first cardiac images were produced using a rectilinear scanner but further advances were made with the development of more suitable radioactive tracers and more sophisticated imaging equipment. The invention of the Anger’s gamma camera in 1957 opened the door for rapid development, initially with blood pool imaging, progressing to myocardial imaging, cardiac PET, and the multi-faceted discipline that is now an essential part of clinical Cardiology. This chapter will summarise the History of Nuclear Cardiology in the UK.
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Nuclear Cardiology practice and associated radiation doses in Europe: results of the IAEA Nuclear Cardiology Protocols Study (INCAPS) for the 27 European countries.
European Journal of Nuclear Medicine and Molecular Imaging, 2015Co-Authors: Oliver Lindner, Juhani Knuuti, Anastasia Kitsiou, Thomas N. B. Pascual, Mathew Mercuri, Wanda Acampa, Wolfgang Burchert, Albert Flotats, Philipp A. Kaufmann, S. Richard UnderwoodAbstract:Purpose Nuclear Cardiology is widely used to diagnose coronary artery disease and to guide patient management, but data on current practices, radiation dose-related best practices, and radiation doses are scarce. To address these issues, the IAEA conducted a worldwide study of Nuclear Cardiology practice. We present the European subanalysis.
Ganesan Karthikeyan - One of the best experts on this subject based on the ideXlab platform.
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opportunities for improvement on current Nuclear Cardiology practices and radiation exposure in latin america findings from the 65 country iaea Nuclear Cardiology protocols cross sectional study incaps
Journal of Nuclear Cardiology, 2017Co-Authors: João V. Vitola, Thomas N. B. Pascual, Mathew Mercuri, Nathan Better, Ganesan Karthikeyan, Fernando Mut, Erick Alexanderson, Madan M Rehani, Ravi Kashyap, Maurizio DondiAbstract:Background Comparison of Latin American (LA) Nuclear Cardiology (NC) practice with that in the rest of the world (RoW) will identify areas for improvement and lead to educational activities to reduce radiation exposure from NC.
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WORLDWIDE VARIATION IN THE USE OF Nuclear Cardiology CAMERA TECHNOLOGY, RECONSTRUCTION SOFTWARE, AND ACQUISITION PROTOCOLS: FINDINGS FROM THE IAEA Nuclear Cardiology PROTOCOLS STUDY (INCAPS)
Journal of the American College of Cardiology, 2017Co-Authors: Edward A. Hulten, Mathew Mercuri, Maurizio Dondi, Thomas N. Pascual, João V. Vitola, Nathan Better, Ganesan Karthikeyan, John J. Mahmarian, Madan Rehani, Diana PaezAbstract:Background: Although increasing attention has been drawn to medical radiation exposure, little is reported about worldwide variation in Nuclear myocardial perfusion imaging (MPI) techniques that may result in differences in radiation exposure. The IAEA Nuclear Cardiology Protocols Study (INCAPS) was
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gender differences in radiation dose from Nuclear Cardiology studies across the world findings from the incaps registry
Jacc-cardiovascular Imaging, 2016Co-Authors: Lynn Shi, Diana Paez, Thomas N. B. Pascual, Leslee J. Shaw, João V. Vitola, Nathan Better, Ganesan Karthikeyan, Sharmila Dorbala, Katherine Zukotynski, Nadia BokhariAbstract:Abstract Objectives The aim of this study was to investigate gender-based differences in Nuclear Cardiology practice globally, with a particular focus on laboratory volume, radiation dose, protocols, and best practices. Background It is unclear whether gender-based differences exist in radiation exposure for Nuclear Cardiology procedures. Methods In a large, multicenter, observational, cross-sectional study encompassing 7,911 patients in 65 countries, radiation effective dose was estimated for each examination. Patient-level best practices relating to radiation exposure were compared between genders. Analysis of covariance was used to determine any difference in radiation exposure according to gender, region, and the interaction between gender and region. Linear, logistic, and hierarchical regression models were developed to evaluate gender-based differences in radiation exposure and laboratory adherence to best practices. The study also included the United Nations Gender Inequality Index and Human Development Index as covariates in multivariable models. Results The proportion of myocardial perfusion imaging studies performed in women varied among countries; however, there was no significant correlation with the Gender Inequality Index. Globally, mean effective dose for Nuclear Cardiology procedures was only slightly lower in women (9.6 ± 4.5 mSv) than in men (10.3 ± 4.5 mSv; p Conclusions Despite significant worldwide variation in best practice use and radiation doses from Nuclear Cardiology procedures, only small differences were observed between genders worldwide. Regional variations noted in myocardial perfusion imaging use and radiation dose offer potential opportunities to address gender-related differences in delivery of Nuclear Cardiology care.
