The Experts below are selected from a list of 198 Experts worldwide ranked by ideXlab platform
Michael I Bennett - One of the best experts on this subject based on the ideXlab platform.
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Paranoid Psychosis due to flecainide toxicity in malignant neuropathic pain
Pain, 1997Co-Authors: Michael I BennettAbstract:Flecainide was used to treat malignant neuropathic pain but despite using therapeutic doses, toxicity occurred resulting in Paranoid Psychosis. Monitoring of flecainide levels in vulnerable populations is suggested to guide prescribing.
P Lenssen - One of the best experts on this subject based on the ideXlab platform.
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p02 233 acute Paranoid Psychosis due to past chronic mangenese exposure
European Psychiatry, 2010Co-Authors: Willem M A Verhoeven, J I M Egger, H J H Kuijpers, P LenssenAbstract:A male patient aged 49 was referred for evaluation of an acute Paranoid psychotic state followed by an apathy syndrome. Since his history, apart from hypertension, did not mention any somatic complaints or psychiatric symptoms, and he had been involved in an adequate professional career as metalworker and welder, MRI- scanning of the brain was performed. There appeared to be bilateral hyperdensity of the globus pallidus, suggestive for chronic manganese (Mn) intoxication. Subsequently, a Mn plasma level of 31 nmol/l (range: 7-20nmol/l) that confirmed the diagnosis. Mn is a trace element that regulates many enzymes and is essential for normal development and body function. Chronic Mn intoxication has an insidious and progressive course and usually starts with complaints of headache, fatigue, sleep disturbances, irritability and emotional instability. Later, several organ systems may be affected leading to increased heart rate and/or blood pressure, elevated total cholesterol levels, and lowered fertility in males. With respect to neurotoxicity, Mn primarily affects the globus pallidus and the striatum of the basal ganglia, and induces damage to the dopaminergic system. This may ultimately lead to dystonic movements and a parkinsonian syndrome that is dominated by generalized bradykinesia and rigidity. As to neuropsychiatry, an array of symptoms may develop up to 30 years after intoxication of which gait and speech abnormalities, cognitive and motor slowing, mood changes and hallucinations are the most common. Psychotic phenomena are rarely reported. In conclusion, subacute psychotic symptoms in the absence of a psychiatric history, may point towards rare occupational diseases.
Sai L Ramanujam - One of the best experts on this subject based on the ideXlab platform.
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Paranoid Psychosis induced by consumption of methylenedioxypyrovalerone two cases
General Hospital Psychiatry, 2011Co-Authors: Joseph L Antonowicz, Amy K Metzger, Sai L RamanujamAbstract:Abstract Of growing concern has been the phenomenon of psychoactive chemicals legally marketed as a variety of products such as “bath salts” or “herbal incense.” There is little in the formal literature about actual adverse effects of such chemicals. We have two cases of a Paranoid Psychosis in individuals consuming methylenedioxypyrovalerone. A discussion of this chemical and its abuse follows.
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case report Paranoid Psychosis induced by consumption of methylenedioxypyrovalerone two cases
2011Co-Authors: Joseph L Antonowicz, Amy K Metzger, Sai L RamanujamAbstract:Of growing concern has been the phenomenon of psychoactive chemicals legally marketed as a variety of products such as “bath salts” or “herbal incense.” There is little in the formal literature about actual adverse effects of such chemicals. We have two cases of a Paranoid
F Hentschel - One of the best experts on this subject based on the ideXlab platform.
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organic factors and the clinical features of late Paranoid Psychosis a comparison with alzheimer s disease and normal ageing
Acta Psychiatrica Scandinavica, 1994Co-Authors: Hans Forstl, P Dalgalarrondo, Anita Riecherrossler, M Lotz, C Geigerkabisch, F HentschelAbstract:: The diagnostic allocation and aetiological basis of Paranoid psychoses with late onset is controversial. We examined the clinical features of patients with a diagnosis of Paranoid Psychosis and we compared their cranial computed tomography (CT) scans and electroencephalographic (EEG) recordings with findings from matched samples of patients with Alzheimer's disease and non-demented elderly controls. During a 5-year period, 81 patients (15 men and 66 women) with a diagnosis of Paranoid Psychosis and onset after age 50 were referred to our Institute. They represent 5.4% of the patients older than 50 admitted during the same period. More than half of these patients had first-rank symptoms. The ventricles, anterior and sylvian fissures of the Paranoid group were larger than in non-demented controls but smaller than in Alzheimer's disease. The posterior dominant alpha EEG rhythm was slower than in normal aging and faster than in Alzheimer's dementia. If Paranoid patients with first-rank symptoms were distinguished from the ones without, the former had less severe brain atrophy and faster posterior dominant rhythm, although they received higher doses of neuroleptics. This could be explained by the existence of at least 2 subgroups of late Paranoid Psychosis: late-onset schizophrenia and organic Paranoid syndrome, the former characterized by first-rank symptoms and less severe brain atrophy, the latter by more severe EEG and CT scan changes with a closer resemblance to degenerative brain disease.
Orest B Boyko - One of the best experts on this subject based on the ideXlab platform.
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cerebral white matter disease in late onset Paranoid Psychosis
Biological Psychiatry, 1990Co-Authors: John C S Breitner, Mustafa M Husain, Gary S Figiel, Ranga K R Krishman, Orest B BoykoAbstract:Abstract We examined magnetic resonance (MR) scans of the heads of 8 patients with late onset Psychosis and 8 aged controls. Although some patients had mild cognitive impairment, none had depression or a history or examination suggesting focal brain disease. Thus, all patients met DSM-III-R criteria for late-onset schizophrenia All 8 patients showed significant leukoencephalopathy or vascular pathology on MR imaging, and temporoparietal and occipital lesions were especially prominent. Little such pathology was evident on control scans. We suggest that focal brain disease of vascular origin may be associated with late-onset Psychosis, and that MR scanning of such cases may provide important clues to pathologenesis.