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Mauricio Castillo - One of the best experts on this subject based on the ideXlab platform.

  • Case Reports
    2016
    Co-Authors: Mauricio Castillo, David F. Merten, Mark C. Weissler
    Abstract:

    Summary: Two newborns presented with severe respiratory distress caused by nasal obstruction. CT showed bilateral soft-tissue masses located under the inferior turbinates at the level of the inferior meatuses. Histologic examination showed the lesions to be compatible with nasolacrimal mucoceles. The embryology and radiographic features of this rare anomaly are discussed. Index terms: Mucocele; Nose, abnormalities and anomalies; Nose, computed tomography; Pediatric Neuroradiology Nasolacrimal duct mucoceles are rare lesions that may cause severe respiratory obstruction in newborns (1, 2). Computed tomography (CT) is the diagnostic method of choice in the evaluation of the newborn with nasal obstruction

  • The Second European Course on Pediatric Neuroradiology, April 15–18 1999
    American Journal of Neuroradiology, 2000
    Co-Authors: Mauricio Castillo
    Abstract:

    The Second European Course on Pediatric Neuroradiology was held in the beautiful town of Rapallo in the Italian Riviera. The course committee was chaired by Dr. Paolo Tortori-Donati from the G. Gaslini Children's Research Hospital in Genova. The course faculty comprised 24 internationally recognized

  • the second european course on Pediatric Neuroradiology april 15 18 1999
    American Journal of Neuroradiology, 2000
    Co-Authors: Mauricio Castillo
    Abstract:

    The Second European Course on Pediatric Neuroradiology was held in the beautiful town of Rapallo in the Italian Riviera. The course committee was chaired by Dr. Paolo Tortori-Donati from the G. Gaslini Children's Research Hospital in Genova. The course faculty comprised 24 internationally recognized

Terry T Yoshizumi - One of the best experts on this subject based on the ideXlab platform.

  • evaluating lens dose reduction in Pediatric Neuroradiology examinations using automated kilovoltage selection software
    American Journal of Roentgenology, 2018
    Co-Authors: Justin Raudabaugh, Aaron K Smith, Bria Moore, Juan Carlos Ramirezgiraldo, Natalie Januzis, Terry T Yoshizumi
    Abstract:

    OBJECTIVE. The purpose of this study is to evaluate the potential of an automated kilo-voltage selection software for the reduction of lens dose in Pediatric CT scans. MATERIALS AND METHODS. Two me...

  • Feasibility of using the computed tomography dose indices to estimate radiation dose to partially and fully irradiated brains in Pediatric Neuroradiology examinations
    Physics in medicine and biology, 2015
    Co-Authors: Natalie Januzis, Giao Nguyen, Donald P. Frush, Jenny K. Hoang, Carolyn Lowry, Terry T Yoshizumi
    Abstract:

    The purpose of this study was two-fold: (a) to measure the dose to the brain using clinical protocols at our institution, and (b) to develop a scanner-independent dosimetry method to estimate brain dose. Radiation dose was measured with a Pediatric anthropomorphic phantom and MOSFET detectors. Six current Neuroradiology protocols were used: brain, sinuses, facial bones, orbits, temporal bones, and craniofacial areas. Two different CT vendor scanners (scanner A and B) were used. Partial volume correction factors (PVCFs) were determined for the brain to account for differences between point doses measured by the MOSFETs and average organ dose. The CTDIvol and DLP for each protocol were recorded. The dose to the brain (mGy) for scanners A and B was 10.7 and 10.0 for the brain protocol, 7.8 and 3.2 for the sinus, 10.2 and 8.6 for the facial bones, 7.4 and 4.7 for the orbits and 1.6 and 1.9 for the temporal bones, respectively. On scanner A, the craniofacial protocol included a standard and high dose option; the dose measured for these exams was 3.9 and 16.9 mGy, respectively. There was only one craniofacial protocol on scanner B; the brain dose measured on this exam was 4.8 mGy. A linear correlation was found between DLP and brain dose with the conversion factors: 0.049 (R(2) = 0.87), 0.046 (R(2) = 0.89) for scanner A and B, and 0.048 (R(2) = 0.89) for both scanners. The range of dose observed was between 1.8 and 16.9 mGy per scan. This suggests that brain dose estimates may be made from DLP.

Catherine Gondry-jouet - One of the best experts on this subject based on the ideXlab platform.

Maarten H Lequin - One of the best experts on this subject based on the ideXlab platform.

  • Added value of arterial spin labeling magnetic resonance imaging in Pediatric Neuroradiology: pitfalls and applications.
    Pediatric Radiology, 2018
    Co-Authors: Vera C. Keil, Daniel J.a. Connolly, Marjolein H G Dremmen, Nolan S Hartkamp, Giovanni Morana, Henk J M M Mutsaerts, Maarten H Lequin
    Abstract:

    Arterial spin labeling is a noninvasive, non-gadolinium-dependent magnetic resonance imaging (MRI) technique to assess cerebral blood flow. It provides insight into both tissue metabolic activity and vascular supply. Because of its non-sensitivity toward blood–brain barrier leakage, arterial spin labeling is also more accurate in cerebral blood flow quantification than gadolinium-dependent methods. The aim of this pictorial essay is to promote the application of arterial spin labeling in Pediatric Neuroradiology. The authors provide information on artifacts and pitfalls as well as numerous fields of application based on Pediatric cases.

  • Will a novel semi-quantitative scale for classification of structural brain MRI improve patient care and research in children with cerebral palsy?
    Developmental medicine and child neurology, 2014
    Co-Authors: Izlem Izbudak, Andrea Poretti, Maarten H Lequin
    Abstract:

    A systematic analysis of neuroimaging studies has been shown to be successful in Pediatric Neuroradiology, e.g. in the evaluation of white matter diseases. 1 Systematic magnetic resonance imaging (MRI) pattern recognition may simplify and guide the diagnosis of classified diseases and makes it possible to cluster patients with identical MR patterns, allowing further clinical, laboratory, genetic, and molecular investigations. Clinical research on homogenous groups of patients could then allow the identification of new diseases or provide information on detailed long-term outcome. Furthermore, systematic evaluation of longitudinal MR studies should help to quantify the success of therapeutic approaches. The application of the same systematic analysis may be helpful to compare data between different institutions, for example in the context of multicentre studies. MRI plays a key role in the diagnostic work-up of children with cerebral palsy (CP). 2 In more than 80% of the children with CP, neuroimaging shows abnormal findings. Correlation between the qualitative neuroimaging findings and (1) pathogenesis of CP, (2) clinical type of CP, and (3) functional outcome of the affected children has been demonstrated. Additionally, a normal brain MRI in a child with CP is a red flag and should prompt clinicians to consider diseases ‘masquerading’ as CP. The qualitative nature of the neuroimaging evaluation in these studies incorporates some limitations such as evaluator dependency and limited reproducibility. Fiori et al. 3 are moving have moved towards reducing these limitations by introducing a novel, highly-reliable, semi-quantitative scoring scale to analyze structural brain MRI in children with CP. This systematic approach quantifies lesion characteristics in different brain regions as a global score as well as subscores that assess the lesions separately based on side, regions, and depth. Further validation studies should confirm the clinical utility of this scoring system in providing a reliable tool to study the relationship between topographical brain abnormalities and clinical function in children with CP. Additionally, the application of this scoring system should facilitate the comparison of patient groups form different centers and increase the multicentre research collaboration. Despite these innovative aspects, the scoring system proposed by Fiori et al. has some limitations. The use of an adult template limits the application of the scoring system to older children (>3 y), while the diagnosis of CP may be made earlier in life. The application only to older children limits the role of the scoring system as a semi-quantitative biomarker of outcome in children with CP. Additionally, the difficulty in delineating the boundaries of abnormal tissue may limit the application of the scoring system to cortical malformations. Another limitation of the proposed scoring system is that it does not allow the differentiation between primary and secondary injuries, e.g. a primary thalamic lesion in a term neonate with acute hypoxic-ischemic injury versus a secondary thalamic involvement in a preterm newborn with periventricular white matter injury. Differentiation between a primary and secondary lesion is important in terms of outcome. We suggest that the authors take these limitations into account and further develop their scoring system accordingly.

Ashok Panigrahy - One of the best experts on this subject based on the ideXlab platform.

  • Magnetic resonance spectroscopy in Pediatric Neuroradiology: Clinical and research applications
    Pediatric Radiology, 2010
    Co-Authors: Ashok Panigrahy, Marvin D. Nelson, Stefan Bluml
    Abstract:

    Magnetic resonance spectroscopy (MRS) offers a unique, noninvasive approach to assess Pediatric neurological abnormalities at microscopic levels by quantifying cellular metabolites. The most widely available MRS method, proton ((1)H; hydrogen) spectroscopy, is FDA approved for general use and can be ordered by clinicians for Pediatric neuroimaging studies if indicated. There are a multitude of both acquisition and post-processing methods that can be used in the implementation of MR spectroscopy. MRS in Pediatric neuroimaging is challenging to interpret because of dramatic normal developmental changes that occur in metabolites, particularly in the first year of life. Still, MRS has been proven to provide additional clinically relevant information for several Pediatric neurological disease processes such as brain tumors, infectious processes, white matter disorders, and neonatal injury. MRS can also be used as a powerful quantitative research tool. In this article, specific research applications using MRS will be demonstrated in relation to neonatal brain injury and Pediatric brain tumor imaging.

  • PET imaging in Pediatric Neuroradiology: current and future applications
    Pediatric Radiology, 2009
    Co-Authors: Noriko Salamon, Stefan Bluml, Hollie A. Jackson, Ashok Panigrahy
    Abstract:

    Molecular imaging with positron emitting tomography (PET) is widely accepted as an essential part of the diagnosis and evaluation of neoplastic and non-neoplastic disease processes. PET has expanded its role from the research domain into clinical application for oncology, cardiology and neuropsychiatry. More recently, PET is being used as a clinical molecular imaging tool in Pediatric neuroimaging. PET is considered an accurate and noninvasive method to study brain activity and to understand Pediatric neurological disease processes. In this review, specific examples of the clinical use of PET are given with respect to Pediatric neuroimaging. The current use of co-registration of PET with MR imaging is exemplified in regard to Pediatric epilepsy. The current use of PET/CT in the evaluation of head and neck lymphoma and Pediatric brain tumors is also reviewed. Emerging technologies including PET/MRI and neuroreceptor imaging are discussed.

  • PET imaging in Pediatric Neuroradiology: current and future applications.
    Pediatric radiology, 2009
    Co-Authors: Sunhee Kim, Stefan Bluml, Noriko Salamon, Hollie A. Jackson, Ashok Panigrahy
    Abstract:

    Molecular imaging with positron emitting tomography (PET) is widely accepted as an essential part of the diagnosis and evaluation of neoplastic and non-neoplastic disease processes. PET has expanded its role from the research domain into clinical application for oncology, cardiology and neuropsychiatry. More recently, PET is being used as a clinical molecular imaging tool in Pediatric neuroimaging. PET is considered an accurate and noninvasive method to study brain activity and to understand Pediatric neurological disease processes. In this review, specific examples of the clinical use of PET are given with respect to Pediatric neuroimaging. The current use of co-registration of PET with MR imaging is exemplified in regard to Pediatric epilepsy. The current use of PET/CT in the evaluation of head and neck lymphoma and Pediatric brain tumors is also reviewed. Emerging technologies including PET/MRI and neuroreceptor imaging are discussed.