The Experts below are selected from a list of 2451 Experts worldwide ranked by ideXlab platform
Etienne Thiry - One of the best experts on this subject based on the ideXlab platform.
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bovine herpesvirus 1 infection and infectious bovine Rhinotracheitis
Veterinary Research, 2007Co-Authors: Benoît Muylkens, Frédéric Schynts, Julien Thiry, Philippe Kirten, Etienne ThiryAbstract:Bovine herpesvirus 1 (BoHV-1), classified as an alphaherpesvirus, is a major pathogen of cattle. Primary infection is accompanied by various clinical manifestations such as infec- tious bovine Rhinotracheitis, abortion, infectious pustular vulvovaginitis, and systemic infection in neonates. When animals survive, a life-long latent infection is established in nervous sensory ganglia. Several reactivation stimuli can lead to viral re-excretion, which is responsible for the maintenance of BoHV-1 within a cattle herd. This paper focuses on an updated pathogenesis based on a molecular characterization of BoHV-1 and the description of the virus cycle. Special emphasis is accorded to the impact of the latency and reactivation cycle on the epidemiology and the control of BoHV-1. Several European countries have initiated BoHV-1 eradication schemes because of the significant losses incurred by disease and trading restrictions. The vaccines used against BoHV-1 are described in this context where the differentiation of infected from vaccinated animals is of critical importance to achieve BoHV-1 eradication.
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Ruminant alphaherpesviruses related to bovine herpesvirus 1
Veterinary research, 2006Co-Authors: Julien Thiry, Benoît Muylkens, Sacha Gogev, Alain Vanderplasschen, François Meurens, Véronique Keuser, Etienne ThiryAbstract:Herpesviruses have mainly co-evolved with their hosts for millions of years. Consequently, different related host species may have been infected by various genetically related herpesviruses. Illustrating this concept, several ruminant alphaherpesviruses have been shown to form a cluster of viruses closely related to bovine herpesvirus 1 (BoHV-1): namely bovine herpesvirus 5, bubaline herpesvirus 1, caprine herpesvirus 1, cervid herpesviruses 1 and 2 and elk herpesvirus 1. These viruses share common antigenic properties and the serological relationships between them can be considered as a threat to BoHV-1 eradication programmes. BoHV-1 is a herpesvirus responsible for infectious bovine Rhinotracheitis, which is a disease of major economic concern. In this article, the genetic properties of these ruminant alphaherpesviruses are reviewed on a comparative basis and the issue of interspecific recombination is assessed. The pathogenesis of these infections is described with emphasis on the host range and crossing of the host species barrier. Indeed, the non bovine ruminant species susceptible to these ruminant alphaherpesviruses may be potential BoHV-1 reservoirs. The differential diagnosis of these related infections is also discussed. In addition, available epidemiological data are used to assess the potential of cross-infection in ruminant populations. A better knowledge of these ruminant alphaherpesvirus infections is essential to successfully control infectious bovine Rhinotracheitis.
Randall J Basaraba - One of the best experts on this subject based on the ideXlab platform.
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infectious bovine Rhinotracheitis parainfluenza 3 and respiratory coronavirus
Veterinary Clinics of North America-food Animal Practice, 1997Co-Authors: Sanjay Kapil, Randall J BasarabaAbstract:A number of viruses have been proven to be primary respiratory pathogens of cattle. Viruses may play an important role in making cattle susceptible to secondary respiratory bacterial pathogens. Epidemiology, pathogenesis, laboratory diagnosis, and important properties in infectious bovine Rhinotracheitis (IBR), parainfluenza-3 (PI-3), and bovine respiratory coronavirus (BRCV) are described in this article.
Benoît Muylkens - One of the best experts on this subject based on the ideXlab platform.
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bovine herpesvirus 1 infection and infectious bovine Rhinotracheitis
Veterinary Research, 2007Co-Authors: Benoît Muylkens, Frédéric Schynts, Julien Thiry, Philippe Kirten, Etienne ThiryAbstract:Bovine herpesvirus 1 (BoHV-1), classified as an alphaherpesvirus, is a major pathogen of cattle. Primary infection is accompanied by various clinical manifestations such as infec- tious bovine Rhinotracheitis, abortion, infectious pustular vulvovaginitis, and systemic infection in neonates. When animals survive, a life-long latent infection is established in nervous sensory ganglia. Several reactivation stimuli can lead to viral re-excretion, which is responsible for the maintenance of BoHV-1 within a cattle herd. This paper focuses on an updated pathogenesis based on a molecular characterization of BoHV-1 and the description of the virus cycle. Special emphasis is accorded to the impact of the latency and reactivation cycle on the epidemiology and the control of BoHV-1. Several European countries have initiated BoHV-1 eradication schemes because of the significant losses incurred by disease and trading restrictions. The vaccines used against BoHV-1 are described in this context where the differentiation of infected from vaccinated animals is of critical importance to achieve BoHV-1 eradication.
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Ruminant alphaherpesviruses related to bovine herpesvirus 1
Veterinary research, 2006Co-Authors: Julien Thiry, Benoît Muylkens, Sacha Gogev, Alain Vanderplasschen, François Meurens, Véronique Keuser, Etienne ThiryAbstract:Herpesviruses have mainly co-evolved with their hosts for millions of years. Consequently, different related host species may have been infected by various genetically related herpesviruses. Illustrating this concept, several ruminant alphaherpesviruses have been shown to form a cluster of viruses closely related to bovine herpesvirus 1 (BoHV-1): namely bovine herpesvirus 5, bubaline herpesvirus 1, caprine herpesvirus 1, cervid herpesviruses 1 and 2 and elk herpesvirus 1. These viruses share common antigenic properties and the serological relationships between them can be considered as a threat to BoHV-1 eradication programmes. BoHV-1 is a herpesvirus responsible for infectious bovine Rhinotracheitis, which is a disease of major economic concern. In this article, the genetic properties of these ruminant alphaherpesviruses are reviewed on a comparative basis and the issue of interspecific recombination is assessed. The pathogenesis of these infections is described with emphasis on the host range and crossing of the host species barrier. Indeed, the non bovine ruminant species susceptible to these ruminant alphaherpesviruses may be potential BoHV-1 reservoirs. The differential diagnosis of these related infections is also discussed. In addition, available epidemiological data are used to assess the potential of cross-infection in ruminant populations. A better knowledge of these ruminant alphaherpesvirus infections is essential to successfully control infectious bovine Rhinotracheitis.
Christopher C L Chase - One of the best experts on this subject based on the ideXlab platform.
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complete genome sequence of bovine herpesvirus type 1 1 bohv 1 1 los angeles la strain and its genotypic relationship to bohv 1 1 cooper and more recently isolated wild type field strains
Archives of Virology, 2019Co-Authors: Jean M Doffay, Robert W Fulton, R Eberle, Edward J Dubovi, Christopher C L ChaseAbstract:The Cooper and Los Angeles (LA) strains were the two original respiratory strains of bovine herpesvirus type 1.1 (BoHV-1.1) isolated in the 1950s from cattle with infectious bovine Rhinotracheitis. We report the complete genome sequence for the BoHV-1.1 LA strain and compare it to the prototype Cooper strain and six wild-type BoHV-1.1 isolates. A nucleotide sequence divergence of 0.74% was noted across the two complete genomes, caused by 19 single-nucleotide polymorphisms (SNPs) involving 12 genes and insertions/deletions that primarily affected the number of repeats within reiterated repeat regions of the genome. Phylogenetic analysis revealed that Cooper and LA strains are genetically the most ancient strains from which all of the more-recently isolated field strains of BoHV-1.1 evolved.
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rapid onset of protection against infectious bovine Rhinotracheitis with a modified live virus multivalent vaccine
Veterinary therapeutics : research in applied veterinary medicine, 2004Co-Authors: Kris Fogarty Fairbanks, Joe Campbell, Christopher C L ChaseAbstract:This study provides evidence that subcutaneous vaccination of cattle with a commercially available modified-live virus combination vaccine can help reduce clinical signs associated with infectious bovine Rhinotracheitis infections in feedlot animals vaccinated at the time of arrival. Calves vaccinated 72 or 96 hours before challenge had reduced clinical signs, lower body temperatures, lower virus titers, and 39% to 76% greater weight gains compared with nonvaccinated controls.
Julien Thiry - One of the best experts on this subject based on the ideXlab platform.
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bovine herpesvirus 1 infection and infectious bovine Rhinotracheitis
Veterinary Research, 2007Co-Authors: Benoît Muylkens, Frédéric Schynts, Julien Thiry, Philippe Kirten, Etienne ThiryAbstract:Bovine herpesvirus 1 (BoHV-1), classified as an alphaherpesvirus, is a major pathogen of cattle. Primary infection is accompanied by various clinical manifestations such as infec- tious bovine Rhinotracheitis, abortion, infectious pustular vulvovaginitis, and systemic infection in neonates. When animals survive, a life-long latent infection is established in nervous sensory ganglia. Several reactivation stimuli can lead to viral re-excretion, which is responsible for the maintenance of BoHV-1 within a cattle herd. This paper focuses on an updated pathogenesis based on a molecular characterization of BoHV-1 and the description of the virus cycle. Special emphasis is accorded to the impact of the latency and reactivation cycle on the epidemiology and the control of BoHV-1. Several European countries have initiated BoHV-1 eradication schemes because of the significant losses incurred by disease and trading restrictions. The vaccines used against BoHV-1 are described in this context where the differentiation of infected from vaccinated animals is of critical importance to achieve BoHV-1 eradication.
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Ruminant alphaherpesviruses related to bovine herpesvirus 1
Veterinary research, 2006Co-Authors: Julien Thiry, Benoît Muylkens, Sacha Gogev, Alain Vanderplasschen, François Meurens, Véronique Keuser, Etienne ThiryAbstract:Herpesviruses have mainly co-evolved with their hosts for millions of years. Consequently, different related host species may have been infected by various genetically related herpesviruses. Illustrating this concept, several ruminant alphaherpesviruses have been shown to form a cluster of viruses closely related to bovine herpesvirus 1 (BoHV-1): namely bovine herpesvirus 5, bubaline herpesvirus 1, caprine herpesvirus 1, cervid herpesviruses 1 and 2 and elk herpesvirus 1. These viruses share common antigenic properties and the serological relationships between them can be considered as a threat to BoHV-1 eradication programmes. BoHV-1 is a herpesvirus responsible for infectious bovine Rhinotracheitis, which is a disease of major economic concern. In this article, the genetic properties of these ruminant alphaherpesviruses are reviewed on a comparative basis and the issue of interspecific recombination is assessed. The pathogenesis of these infections is described with emphasis on the host range and crossing of the host species barrier. Indeed, the non bovine ruminant species susceptible to these ruminant alphaherpesviruses may be potential BoHV-1 reservoirs. The differential diagnosis of these related infections is also discussed. In addition, available epidemiological data are used to assess the potential of cross-infection in ruminant populations. A better knowledge of these ruminant alphaherpesvirus infections is essential to successfully control infectious bovine Rhinotracheitis.
