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Didier Raoult - One of the best experts on this subject based on the ideXlab platform.
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Molecular Evidence of Rickettsia slovaca in Wild Boar Lice, in Northeastern Algeria.
Vector borne and zoonotic diseases (Larchmont N.Y.), 2018Co-Authors: F. Zeroual, Philippe Parola, Didier Raoult, Hamza Leulmi, A. Benakhla, I. BitamAbstract:Abstract Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group Rickettsia was assessed in 92/325 lice collected on 117 wild boars hunted in the far northeast of Algeria. Ov...
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Molecular Evidence of Rickettsia slovaca in Wild Boar Lice, in Northeastern Algeria
Vector-Borne and Zoonotic Diseases, 2018Co-Authors: F. Zeroual, Philippe Parola, Didier Raoult, Hamza Leulmi, A. Benakhla, I. BitamAbstract:Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group Rickettsia was assessed in 92/325 lice collected on 117 wild boars hunted in the far northeast of Algeria. Overall, 7/92 (7.61%) Haematopinus suis were found positive to R. slovaca. The presence of R. slovaca DNA on H. suis questions about the relationship that may exist between R. slovaca and lice.
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Rickettsia massiliae infection and SENLAT syndrome in Romania.
Ticks and tick-borne diseases, 2016Co-Authors: Mihaela Zaharia, Philippe Parola, Didier Raoult, Corneliu Petru Popescu, Simin Aysel Florescu, Emanoil Ceausu, Cristina SocolovschiAbstract:The purpose of this prospective study is to describe the clinical and epidemiological characteristics of rickettsioses in Romania, where only Rickettsia conorii is known by clinicians but new Rickettsia species have been identified recently in ticks. A total of eight patients, including a nine-year-old child, were included between June 2011 and June 2012, in the Hospital for Infectious and Tropical Diseases, Bucharest, Romania. Seven cases presented during summer months and one in spring. Six patients presented a generalized rash with fever, myalgia and skin eschar. The last two patients presented a typical SENLAT syndrome, characterized by scalp eschar and neck lymphadenopathy. Using serological tools, we confirmed for the first time two cases of Rickettsia massiliae, the agent of spotted fever disease, and one case of Rickettsia slovaca, and one case of R. slovacaRickettsia raoultii the agents of SENLAT syndrome.
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Bacterial agents in 248 ticks removed from people from 2002 to 2013
Ticks and tick-borne diseases, 2016Co-Authors: Camille Aubry, Cristina Socolovschi, Didier Raoult, Philippe ParolaAbstract:A retrospective study was conducted to analyze the tick species removed from people and to detect tick-infecting bacteria in the specimens collected over the past 10 years at the reference center for rickettsioses, Marseille, France. A total of 248 ticks were removed from 200 people, including Dermacentor (73), Rhipicephalus (67), Ixodes (60), Amblyomma (8), Argas (3), Hyalomma (1), and Haemaphysalis (1) species. Bacterial DNA was detected in 101 ticks: Rickettsia slovaca (34%) and Rickettsia raoultii (23%) were detected in Dermacentor ticks; Rickettsia conorii (16%) and Rickettsia massiliae (18%) were found in Rhipicephalus ticks; and Anaplasma phagocytophylum (5%), Borrelia spp. (8%) and Rickettsia spp. (2%) were detected in Ixodes ticks. Among the bitten people for which clinical data and laboratory samples were available, tick borne diseases were confirmed in 11 symptomatic individuals.
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Bacterial agents in 248 ticks removed from people from 2002 to 2013
TICKS AND TICK-BORNE DISEASES, 2016Co-Authors: Camille Aubry, Cristina Socolovschi, Didier Raoult, Philippe ParolaAbstract:A retrospective study was conducted to analyze the tick species removed from people and to detect tick-infecting bacteria in the specimens collected over the past 10 years at the reference center for rickettsioses, Marseille, France. A total of 248 ticks were removed from 200 people, including Dermacentor (73), Rhipicephalus (67), Ixodes (60), Amblyomma (8), Argas (3), Hyalomma (1), and Haemaphysalis (1) species. Bacterial DNA was detected in 101 ticks: Rickettsia slovaca (34%) and Rickettsia raoultii (23%) were detected in Dermacentor ticks; Rickettsia conorii (16%) and Rickettsia massiliae (18%) were found in Rhipicephalus ticks; and Anaplasma phagocytophylum (5%), Borrelia spp. (8%) and Rickettsia spp. (2%) were detected in Ixodes ticks. Among the bitten people for which clinical data and laboratory samples were available, tick borne diseases were confirmed in 11 symptomatic individuals. (C) 2016 Elsevier GmbH. All rights reserved.
Philippe Parola - One of the best experts on this subject based on the ideXlab platform.
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Molecular Evidence of Rickettsia slovaca in Wild Boar Lice, in Northeastern Algeria.
Vector borne and zoonotic diseases (Larchmont N.Y.), 2018Co-Authors: F. Zeroual, Philippe Parola, Didier Raoult, Hamza Leulmi, A. Benakhla, I. BitamAbstract:Abstract Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group Rickettsia was assessed in 92/325 lice collected on 117 wild boars hunted in the far northeast of Algeria. Ov...
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Molecular Evidence of Rickettsia slovaca in Wild Boar Lice, in Northeastern Algeria
Vector-Borne and Zoonotic Diseases, 2018Co-Authors: F. Zeroual, Philippe Parola, Didier Raoult, Hamza Leulmi, A. Benakhla, I. BitamAbstract:Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group Rickettsia was assessed in 92/325 lice collected on 117 wild boars hunted in the far northeast of Algeria. Overall, 7/92 (7.61%) Haematopinus suis were found positive to R. slovaca. The presence of R. slovaca DNA on H. suis questions about the relationship that may exist between R. slovaca and lice.
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Detection of Rickettsia hoogstraalii, Rickettsia helvetica, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii in ticks from Sardinia, Italy.
Ticks and Tick-borne Diseases, 2017Co-Authors: Valentina Chisu, Cipriano Foxi, Giovanna Masala, Hamza Leulmi, Mariano Piredda, Philippe ParolaAbstract:Tick-borne diseases represent a large proportion of infectious diseases that have become a world health concern. The presence of Rickettsia spp. was evaluated by standard PCR and sequencing in 123 ticks collected from several mammals and vegetation in Sardinia, Italy. This study provides the first evidence of the presence of Rickettsia hoogstralii in Haemaphysalis punctata and Haemaphysalis sulcata ticks from mouflon and Rickettsia helvetica in Ixodes festai ticks from hedgehog. In addition, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii were detected in Rhipicephalus sanguineus, Dermacentor marginatus and Hyalomma marginatum marginatum ticks from foxes, swine, wild boars, and mouflon. The data presented here increase our knowledge of tick-borne diseases in Sardinia and provide a useful contribution toward understanding their epidemiology.
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Detection of Rickettsia hoogstraalii, Rickettsia helvetica, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii in ticks from Sardinia, Italy
Ticks and Tick-borne Diseases, 2017Co-Authors: Valentina Chisu, Cipriano Foxi, Giovanna Masala, Hamza Leulmi, Mariano Piredda, Philippe ParolaAbstract:Tick-borne diseases represent a large proportion of infectious diseases that have become a world health concern. The presence of Rickettsia spp. was evaluated by standard PCR and sequencing in 123 ticks collected from several mammals and vegetation in Sardinia, Italy. This study provides the first evidence of the presence of Rickettsia hoogstralii in Haemaphysalis punctata and Haemaphysalis sulcata ticks from mouflon and Rickettsia helvetica in Ixodes festai ticks from hedgehog. In addition, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii were detected in Rhipicephalus sanguineus, Dermacentor marginatus and Hyalomma marginatum marginatum ticks from foxes, swine, wild boars, and mouflon. The data presented here increase our knowledge of tick-borne diseases in Sardinia and provide a useful contribution toward understanding their epidemiology. (C) 2016 Elsevier GmbH. All rights reserved.
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Rickettsia massiliae infection and SENLAT syndrome in Romania.
Ticks and tick-borne diseases, 2016Co-Authors: Mihaela Zaharia, Philippe Parola, Didier Raoult, Corneliu Petru Popescu, Simin Aysel Florescu, Emanoil Ceausu, Cristina SocolovschiAbstract:The purpose of this prospective study is to describe the clinical and epidemiological characteristics of rickettsioses in Romania, where only Rickettsia conorii is known by clinicians but new Rickettsia species have been identified recently in ticks. A total of eight patients, including a nine-year-old child, were included between June 2011 and June 2012, in the Hospital for Infectious and Tropical Diseases, Bucharest, Romania. Seven cases presented during summer months and one in spring. Six patients presented a generalized rash with fever, myalgia and skin eschar. The last two patients presented a typical SENLAT syndrome, characterized by scalp eschar and neck lymphadenopathy. Using serological tools, we confirmed for the first time two cases of Rickettsia massiliae, the agent of spotted fever disease, and one case of Rickettsia slovaca, and one case of R. slovacaRickettsia raoultii the agents of SENLAT syndrome.
Eva Špitalská - One of the best experts on this subject based on the ideXlab platform.
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Comparative proteomics of the vector Dermacentor reticulatus revealed differentially regulated proteins associated with pathogen transmission in response to laboratory infection with Rickettsia slovaca
Parasites & Vectors, 2019Co-Authors: Gabriela Flores-ramirez, Eva Špitalská, Balázs Sallay, Maksym Danchenko, Olha Lakhneko, Ludovit SkultetyAbstract:Background Tick-borne Rickettsial diseases are caused by pathogens acquired from hard ticks. In particular, Rickettsia slovaca , a zoonotic infectious bacterium causing tick-borne lymphadenopathy (TIBOLA), is transmitted by the vectors Dermacentor spp. that can be found all over Europe. Although recent studies point out the extreme complexity of bacteria-induced effects in these blood-feeding vectors, the knowledge of individual molecules involved in the preservation and transmission of the pathogen is still limited. System biology tools, including proteomics, may contribute greatly to the understanding of pathogen-tick-host interactions. Methods Herein, we performed a comparative proteomics study of the tick vector Dermacentor reticulatus that was experimentally infected with the endosymbiotic bacterium R. slovaca . Rickettsia -free ticks, collected in the southern region of Slovakia, were infected with the bacterium by a capillary tube-feeding system, and the dynamics of infection was assessed by quantitative PCR method after 5, 10, 15 and 27 days. Results At the stage of controlled proliferation (at 27 dpi), 33 (from 481 profiled) differentially abundant protein spots were detected on a two-dimensional gel. From the aforementioned protein spots, 21 were successfully identified by tandem mass spectrometry. Conclusions Although a few discovered proteins were described as having structural or housekeeping functions, the vast majority of the affected proteins were suggested to be essential for tick attachment and feeding on the host, host immune system evasion and defensive response modulation to ensure successful pathogen transmission.
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Comparative proteomics of the vector Dermacentor reticulatus revealed differentially regulated proteins associated with pathogen transmission in response to laboratory infection with Rickettsia slovaca
Parasites & vectors, 2019Co-Authors: Gabriela Flores-ramirez, Eva Špitalská, Balázs Sallay, Maksym Danchenko, Olha Lakhneko, Ludovit SkultetyAbstract:Tick-borne Rickettsial diseases are caused by pathogens acquired from hard ticks. In particular, Rickettsia slovaca, a zoonotic infectious bacterium causing tick-borne lymphadenopathy (TIBOLA), is transmitted by the vectors Dermacentor spp. that can be found all over Europe. Although recent studies point out the extreme complexity of bacteria-induced effects in these blood-feeding vectors, the knowledge of individual molecules involved in the preservation and transmission of the pathogen is still limited. System biology tools, including proteomics, may contribute greatly to the understanding of pathogen-tick-host interactions. Herein, we performed a comparative proteomics study of the tick vector Dermacentor reticulatus that was experimentally infected with the endosymbiotic bacterium R. slovaca. Rickettsia-free ticks, collected in the southern region of Slovakia, were infected with the bacterium by a capillary tube-feeding system, and the dynamics of infection was assessed by quantitative PCR method after 5, 10, 15 and 27 days. At the stage of controlled proliferation (at 27 dpi), 33 (from 481 profiled) differentially abundant protein spots were detected on a two-dimensional gel. From the aforementioned protein spots, 21 were successfully identified by tandem mass spectrometry. Although a few discovered proteins were described as having structural or housekeeping functions, the vast majority of the affected proteins were suggested to be essential for tick attachment and feeding on the host, host immune system evasion and defensive response modulation to ensure successful pathogen transmission.
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Evaluation of the possible use of genus Mentha derived essential oils in the prevention of SENLAT syndrome caused by Rickettsia slovaca
Journal of ethnopharmacology, 2018Co-Authors: Katarína Štefanidesová, Eva Špitalská, Frantisek Csicsay, Viera Friedländerová, Andrej Šáner, Ľudovít ŠkultétyAbstract:Abstract Ethnopharmacological relevance Essential oils and essential oil bearing medicinal and culinary plants have a long tradition of being used to combat infection, treat various conditions, and promote and restore health. Mint oils are traditionally applied to repel insects and treat various conditions including wounds, skin infections, inflammation, eczema, urticaria, psoriasis, scabies and insect bites. They are among essential oils promoted as a natural way to prevent tick-borne diseases and recommended as ingredients in various homemade repellent mixtures and tick-bite treatments. Aim of the study The aim of this study was to evaluate the effect of three most common mint oils - peppermint (Mentha x piperita L.), cornmint (M. arvensis L.), and spearmint (M. spicata L.) on obligate intracellular tick-borne bacterium Rickettsia slovaca. Materials and methods Influence of mint oils on R. slovaca replication in Vero cells initially infected by lower (106) or higher (108) number of Rickettsial particles was tested during in vitro cultivation with daily change of medium. qPCR and RT-qPCR based growth curves and linear mixed effect models were applied to evaluate the growth inhibition. Peppermint oil was further tested in pilot in vivo study on experimentally infected ticks. Results Two of the tested essential oils, peppermint and cornmint, significantly inhibited Rickettsial growth. On average, peppermint oil reduced the amount of Rickettsiae present on day 4 post infection up to 0.05% of the Rickettsial load present in the respective controls. Cornmint oil decreased the amount of Rickettsiae to 0.09% of control. Peppermint oil also significantly reduced the number of living Rickettsiae in artificially infected ticks. Conclusions Present study showed that essential oils with antimicrobial properties may also inhibit tick-transmitted bacteria, and thus their possible use as preventative measures against tick-borne diseases is worth further research.
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Low-cost light-induced therapy to treat Rickettsial infection.
Photodiagnosis and photodynamic therapy, 2018Co-Authors: Eva Špitalská, Katarína Štefanidesová, Zdenko Špitalský, Zoran Markovic, Ľudovít ŠkultétyAbstract:Abstract Antimicrobial photodynamic therapy uses a nontoxic photosensitizer with the assistance of harmless visible light to activate the photosensitizer. Consequently, the excited state of the photosensitizer interacts with molecular oxygen to produce reactive oxygen species, which have the antimicrobial effect. In this study, we evaluated the effect of photodynamic therapy on Vero cells infected with Rickettsia using methylene blue as a photosensitizer along with red light. A significant reduction (by 96%) in the number of viable Rickettsia slovaca was determined by quantitative RT-PCR 48 h after the treatment with methylene blue followed by 30 min of red light excitation. A statistically significant reduction of R. slovaca was also recorded with pretreatment (by 99%). To the best of our knowledge, this result is the first one in the literature to confirm the effectiveness of photodynamic therapy for the elimination of R. slovaca and to suggest this technique as a good supportive treatment for Rickettsial infections.
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Rickettsia slovaca and Rickettsia raoultii in dermacentor marginatus and dermacentor reticulatus ticks from slovak republic
Experimental and Applied Acarology, 2012Co-Authors: Eva Špitalská, Elena Kocianová, Katarína Štefanidesová, Vojtech BoldišAbstract:Rickettsiae, obligate intracellular Gram-negative bacteria, responsible for mild to severe diseases in humans are associated with arthropod vectors. Dermacentor marginatus and Dermacentor reticulatus are known vectors of Rickettsia slovaca and Rickettsia raoultii distributed across Europe. A total of 794 D. marginatus, D. reticulatus and Ixodes ricinus adult ticks were collected from the vegetation, removed from horses, sheep, goats and dogs in Slovakia. The DNA of Rickettsia sp. was found in 229 ticks by PCR amplifying parts of gltA, ompA and sca4 genes. Next analyses of Rickettsia-positive samples by PCR–RFLP and/or sequencing showed D. reticulatus ticks were more infected with R. raoultii and D. marginatus were more infected with R. slovaca. The prevalence of R. raoultii was 8.1–8.6% and 22.3–27% in D. marginatus and D. reticulatus, respectively. The prevalence of R. slovaca was 20.6–24.3% in D. marginatus and 1.7–3.4% in D. reticulatus. Intracellular growth of R. raoultii isolate from D. marginatus tick was evaluated by rOmpA-based quantitative SybrGreen PCR assay. The highest point of multiplication was recorded on the 7th and 8th day postinfection in Vero and L929 cells, respectively. R. raoultii was transmitted during feeding of R. raoultii-positive ticks to guinea pigs and subsequently Rickettsial infection was recorded in all organs, the highest infection was in spleen, liver and heart. Our study describes the detection and isolation of tick-borne pathogens R. raoultii and R. slovaca, show that they are spread in Slovakia and highlight their risk for humans.
Philippe Brouqui - One of the best experts on this subject based on the ideXlab platform.
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Rickettsia slovaca and r raoultii in tick borne rickettsioses
Emerging Infectious Diseases, 2009Co-Authors: Philippe Parola, Clarisse Rovery, Philippe Brouqui, Jean-marc Rolain, Bernard DavoustAbstract:Tick-borne lymphadenopathy (TIBOLA), also called Dermacentor-borne necrosis erythema and lymphadenopathy (DEBONEL), is defined as the association of a tick bite, an inoculation eschar on the scalp, and cervical adenopathies. We identified the etiologic agent for 65% of 86 patients with TIBOLA/DEBONEL as either Rickettsia slovaca (49/86, 57%) or R. raoultii (7/86, 8%).
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Rickettsia slovaca and r raoultii in tick borne rickettsioses
Emerging Infectious Diseases, 2009Co-Authors: Philippe Parola, Clarisse Rovery, Philippe Brouqui, Jean-marc Rolain, Bernard Davoust, Didier RaoultAbstract:Tick-borne lymphadenopathy (TIBOLA), also called Dermacentor-borne necrosis erythema and lymphadenopathy (DEBONEL), is defined as the association of a tick bite, an inoculation eschar on the scalp, and cervical adenopathies. We identified the etiologic agent for 65% of 86 patients with TIBOLA/DEBONEL as either Rickettsia slovaca (49/86, 57%) or R. raoultii (7/86, 8%).
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spotted fever rickettsioses in southern and eastern europe
Fems Immunology and Medical Microbiology, 2007Co-Authors: Philippe Brouqui, Philippe Parola, Pierre-edouard FournierAbstract:Mediterranean spotted fever due to Rickettsia conorii conorii was thought, for many years, to be the only tick-borne Rickettsial disease prevalent in southern and eastern Europe. However, in recent years, six more species or subspecies within the spotted fever group of the genus Rickettsia have been described as emerging pathogens in this part of the world. Tick-borne agents include Rickettsia conorii israelensis, Rickettsia conorii caspia, Rickettsia aeschlimannii, Rickettsia slovaca, Rickettsia sibirica mongolitimonae and Rickettsia massiliae. Many Rickettsia of unknown pathogenicity have also been detected from ticks and could represent potential emerging pathogens to be discovered in the future. Furthermore, a new spotted fever Rickettsia, Rickettsia felis, was found to be associated with cat fleas and is an emerging human pathogen. Finally, the mite-transmitted Rickettsia akari, the agent of Rickettsialpox, is also known to be prevalent in Europe. We present here an overview of these rickettsioses, focusing on emerging diseases.
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concomitant or consecutive infection with coxiella burnetii and tickborne diseases
Clinical Infectious Diseases, 2005Co-Authors: Jean-marc Rolain, Philippe Brouqui, Frédérique Gouriet, D Larrey, F Janbon, Sirkka Vene, V Jarnestrom, Didier RaoultAbstract:Background. Q fever is a worldwide zoonosis caused by Coxiella burnetii, which can be isolated from ticks. Reports of people with both Q fever and other tickborne diseases are rare. In this study, we describe 6 patients with Q fever who were infected with 1 of the following tickborne pathogens: Rickettsia conorii (2 patients), Rickettsia slovaca (2), Rickettsia africae (1), and Francisella tularensis (1). Methods. Diagnoses were made on the basis of results of microimmunofluorescence assays for detection of C. burnetii, R. conorii, R. slovaca, R. africae, and F. tularensis antigens. Cross-adsorption studies and Western blots were used to confirm dual infections. Results. Among the 6 cases presented, 3 were probably due to a concomitant infection after a tick bite, whereas the remaining 3 were more likely consecutive infections. Conclusions. Because acute Q fever is often asymptomatic, we recommend that patients infected with the tickborne pathogens mentioned above also undergo routine testing for concurrent infections with C. burnetii.
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Prevalence of Rickettsia spp. in Dermacentor marginatus ticks removed from game pigs (Sus scrofa) in southern France.
Annals of the New York Academy of Sciences, 2003Co-Authors: Y. O. Sanogo, Philippe Brouqui, Philippe Parola, Bernard Davoust, Jean-louis Camicas, Didier RaoultAbstract:During the months of October and November 2000 a total of 70 Dermacentor marginatus ticks were removed from different game pigs Sus scrofa in southern France and investigated by PCR using primers derived from the citrate synthase (gltA) and the outer membrane protein (OmpB) genes of Rickettsiae. Based on sequence analysis of 1,150 bp fragment of gltA, Rickettsia slovaca was identified in 11 ticks (15.7%). These results confirm that Rickettsia slovaca, an emerging pathogen is highly prevalent in Dermacentor marginatus ticks in France. Moreover, a new Rickettsia genotype was detected in one specimen (1.4%). The pathogenic role of this new Rickettsia has yet to be demonstrated.
I. Bitam - One of the best experts on this subject based on the ideXlab platform.
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neglected vector borne bacterial diseases and arboviruses in the mediterranean area
new microbes and new infections, 2018Co-Authors: Remi N Charrel, I. Bitam, Jeanmichel Berenger, Maureen Laroche, Nazli Ayhan, Pascal Delaunay, P ParolaAbstract:Arthropod vectors can transmit pathogenic microorganisms from one vertebrate to another during their blood meal. Although some vector-borne diseases have been eradicated in the Mediterranean area, such as malaria and dengue, recent endemic microorganisms (Toscana virus, Rickettsia spp.) remain neglected even though they cause many more cases. New diagnostic tools and innovative tools for the identification and characterization of vector species and microorganisms have been developed at IHU Mediterranee Infection, either internally or through collaborative and integrated projects. We have detected Rickettsia slovaca as a human pathogen and have described the disease; we have shown that Rickettsia felis can be transmitted by Anopheles mosquitoes; we have emphasized the increasing importance of bedbug (Cimex lectularius) as a potential vector of Bartonella quintana; and we have described the Toscana virus, a major agent of meningitis and meningoencephalitis which was disseminated in North Africa and Central and Eastern Europe, where it frequently cocirculates with a large number of newly described phleboviruses transmitted by sand flies.
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Molecular evidence of Rickettsia slovaca in spleen of wild boars in northeastern Algeria.
New microbes and new infections, 2018Co-Authors: F. Zeroual, Hamza Leulmi, I. Bitam, A. BenakhlaAbstract:Abstract Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group rickettsiosis resulting in scalp eschar and neck lymphadenopathy after tick bite, was assessed in 92 spleens recovered from 117 wild boars hunted in the far northeast of Algeria. Rickettsia slovaca was detected in 5.4% of tested wild boar spleens. The presence of R. slovaca DNA in boar spleens questions the relationship that may exist between this bacterium and Sus scrofa algira, and its role in human infections.
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Molecular Evidence of Rickettsia slovaca in Wild Boar Lice, in Northeastern Algeria.
Vector borne and zoonotic diseases (Larchmont N.Y.), 2018Co-Authors: F. Zeroual, Philippe Parola, Didier Raoult, Hamza Leulmi, A. Benakhla, I. BitamAbstract:Abstract Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group Rickettsia was assessed in 92/325 lice collected on 117 wild boars hunted in the far northeast of Algeria. Ov...
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Molecular evidence of Rickettsia slovaca in spleen of wild boars in northeastern Algeria
Elsevier, 2018Co-Authors: F. Zeroual, H. Leulmi, I. Bitam, A. BenakhlaAbstract:Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group rickettsiosis resulting in scalp eschar and neck lymphadenopathy after tick bite, was assessed in 92 spleens recovered from 117 wild boars hunted in the far northeast of Algeria. Rickettsia slovaca was detected in 5.4% of tested wild boar spleens. The presence of R. slovaca DNA in boar spleens questions the relationship that may exist between this bacterium and Sus scrofa algira, and its role in human infections. Keywords: Algeria, Haematopinus suis, Rickettsia slovaca, Spleen, Wild boa
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Molecular Evidence of Rickettsia slovaca in Wild Boar Lice, in Northeastern Algeria
Vector-Borne and Zoonotic Diseases, 2018Co-Authors: F. Zeroual, Philippe Parola, Didier Raoult, Hamza Leulmi, A. Benakhla, I. BitamAbstract:Using molecular assays, Rickettsia slovaca, the agent of a spotted fever group Rickettsia was assessed in 92/325 lice collected on 117 wild boars hunted in the far northeast of Algeria. Overall, 7/92 (7.61%) Haematopinus suis were found positive to R. slovaca. The presence of R. slovaca DNA on H. suis questions about the relationship that may exist between R. slovaca and lice.