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William Devizio - One of the best experts on this subject based on the ideXlab platform.
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Clinical Stain Removal efficacy of two dentifrices after one and two weeks of use.
The Journal of clinical dentistry, 2020Co-Authors: Prem K. Sreenivasan, William Devizio, K. V. V. Prasad, G. Rajesh, R. KalyanpurAbstract:OBJECTIVE: This investigation evaluated extrinsic Stain Removal efficacy after brushing for one and two weeks with a commercially available fluoride dentifrice relative to Colgate Total Advanced Clean, a new dentifrice formulated with dual-phase silica. METHODS: At the baseline visit, one-hundred and forty-four adult subjects were stratified by Lobene Stain Index scores and randomized to two treatment groups using either Total Advanced Clean dentifrice (0.3% triclosan, 2% copolymer, dual phase silica) or a commercially available fluoride dentifrice, and instructed to brush twice daily. Tooth Stain evaluations were conducted on Stain area, Stain intensity, and a composite score of both, after one and two weeks of dentifrice use. RESULTS: Baseline scores demonstrated no significant differences between the two treatment groups for all evaluated Stain parameters (p > 0.05). At both the one- and two-week post-use evaluations, subjects brushing with Total Advanced Clean demonstrated significant reductions for all Stain parameters versus the control (p < 0.05). The Total Advanced Clean group demonstrated mean reductions in Stain intensity of 0.37 and 0.74 at the one- and two-week evaluations, respectively, versus the control group. Corresponding mean reductions in Stain area for the Total Advanced Clean group versus the control were 0.12 and 0.24 at the one- and two-week evaluations, respectively. The two post-use evaluations also demonstrated significant reductions in Stain composite scores for the subjects assigned Total Advanced Clean (p < 0.0001). CONCLUSION: In comparison to the control dentifrice, the results demonstrated significantly more Stain Removal following the use of Total Advanced Clean at each recall visit. Subjects assigned Total Advanced Clean demonstrated continued reductions in Stains from baseline to one week, and from one week to two weeks.
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Clinical comparison of the Stain-Removal efficacy of a novel liquid whitening gel containing 18% carbamide peroxide and a commercially available whitening dentifrice.
Compendium of continuing education in dentistry (Jamesburg N.J. : 1995), 2020Co-Authors: Farid Ayad, William Devizio, Martin Giniger, Howard M Proskin, John P Curtis, Peter P Santarpia, Bernal Stewart, Margaret Petrone, Anthony R VolpeAbstract:The objective of this examiner-blind clinical study was to compare the extrinsic tooth-Stain Removal efficacy of a novel, nontray, "paint-on" liquid whitening gel containing 18% carbamide peroxide (Colgate Simply White Clear Whitening Gel) with a commercially available whitening dentifrice. After a baseline examination for extrinsic tooth Stain, qualifying adult men and women from Canada were randomized into two treatment groups balanced for age, gender, and level of extrinsic tooth Stain. Subjects were instructed to brush their teeth twice daily (morning and evening) for 1 minute with their assigned dentifrice (Group 1: nonwhitening dentifrice; Group 2: whitening dentifrice). The subjects in Group 1 also were instructed to use the paint-on whitening gel for 30 minutes twice daily. Examinations for extrinsic tooth Stain were repeated after 2 and 3 weeks. Ninety-seven subjects complied with the protocol and completed the entire study. At both the 2- and 3-week examinations, subjects assigned to the liquid whitening gel-treatment group exhibited statistically significant reductions in extrinsic tooth Stain (P < .05) with respect to Stain area (22.7% reduction at 3 weeks), Stain intensity (26.3% reduction at 3 weeks), and overall Stain Removal (32% reduction at 3 weeks) compared with the commercially available whitening dentifrice group. Thus, the results of the examiner-blind clinical study support the conclusion that Colgate Simply White Clear Whitening Gel provides a significantly greater level of extrinsic tooth-Stain Removal efficacy than a commercially available whitening dentifrice.
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A six-week clinical study to compare the Stain Removal efficacy of three dentifrices.
The Journal of clinical dentistry, 2020Co-Authors: Salim Nathoo, Margaret Petrone, William Devizio, Chaknis P, Anthony R VolpeAbstract:: The objective of this double-blind clinical study was to compare the tooth whitening efficacy (Stain Removal) of a new commercially available tooth whitening dentifrice (Colgate Total Plus Whitening Toothpaste) containing 0.2% triclosan and 3.0% PVM/MA copolymer in a 0.243% sodium fluoride/high cleaning silica base, with that of two commercially available dentifrices, Crest Multi-Care Advanced Cleaning Toothpaste and Colgate Winterfresh Gel Fluoride Toothpaste. Following a baseline examination to assess extrinsic tooth Stain, qualifying adult male and female subjects were randomized into three treatment groups which were balanced for gender, age and level of extrinsic tooth Stain. Subjects were asked to brush their teeth twice (morning and evening) for one minute with their assigned dentifrice using a soft-bristled toothbrush. Examinations for extrinsic tooth Stain were repeated after six weeks' use of the study dentifrices. One-hundred and twenty-three (123) subjects complied with the protocol and completed the study. At the six-week examination, subjects assigned to the Colgate Total Plus Whitening Toothpaste treatment group exhibited statistically significant reductions in extrinsic tooth Stain area and extrinsic tooth Stain intensity relative to those subjects assigned to the Crest Multi-Care Advanced Cleaning Toothpaste and the Colgate Winterfresh Gel Fluoride Toothpaste.
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Clinical studies to assess the extrinsic Stain prevention and Stain Removal efficacy of a variant of a commercially available dentifrice containing a new dual silica system.
The Journal of clinical dentistry, 2020Co-Authors: Salim Nathoo, William Devizio, Singh Sm, Petrone Dm, Gerald N Wachs, Pat Chaknis, Howard M ProskinAbstract:OBJECTIVE: The objective of these two six-week, double-blind clinical studies was to compare the extrinsic Stain prevention (Study #1) and Stain Removal (Study #2) efficacy of a new dentifrice (Colgate Total Advanced Toothpaste) containing 0.3% triclosan/ 2.0% polyvinylmethyl ether/maleic acid (PVM/MA) copolymer/0.243% sodium fluoride in a 17% dual silica base, to a commercially available fluoride dentifrice without tooth whitening ingredients (Crest Cavity Protection Toothpaste) containing 0.243% sodium fluoride in a silica base. METHODS: Following baseline examinations for extrinsic tooth Stain and an oral tissue examination, qualifying adult male and female subjects from the northern and central New Jersey, USA areas were randomized for each study into two treatment groups which were balanced for gender and level of extrinsic tooth Stain. Subjects received a full oral prophylaxis at the start of Study #1 only. All subjects were provided with their assigned product and a soft-bristled adult toothbrush for home use. Subjects were instructed to brush their teeth for one minute twice daily (morning and evening) using only the dentifrice and toothbrush provided, and to refrain from using any other oral hygiene products for the entire six weeks of the study. There were no restrictions regarding diet or smoking habits during the course of the study. Examinations for extrinsic tooth Stain and oral tissue assessments were repeated after three weeks and six weeks of product use. RESULTS: One-hundred fourteen (114) subjects participating in Study #1 and 119 subjects participating in Study #2 complied with the protocol and completed the entire study. In both studies, at the three-week and the six-week examinations, subjects who used the new dentifrice exhibited statistically significantly lower levels of extrinsic tooth Stain area and extrinsic tooth Stain intensity than did those subjects who used the commercially available fluoride control dentifrice. CONCLUSION: A new dentifrice containing 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride in a 17% dual silica base is more efficacious in the prevention and Removal of extrinsic tooth Stain than a commercially marketed fluoride dentifrice.
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Comparative tooth whitening and extrinsic tooth Stain Removal efficacy of two tooth whitening dentifrices: six-week clinical trial.
The Journal of clinical dentistry, 2018Co-Authors: Soparkar P, Kedar N. Rustogi, William Devizio, Margaret Petrone, Yun Po Zhang, Howard M ProskinAbstract:OBJECTIVE: The objective of this six-week, examiner-blind clinical study was to assess the tooth whitening and extrinsic tooth Stain Removal efficacy of a new dentifrice delivering 1.0% hydrogen peroxide, 0.243% sodium fluoride, and sodium tripolyphosphate in a high-cleaning silica base (Test Dentifrice), relative to that of commercially available hexametaphosphate-containing whitening dentifrice (Positive Control Dentifrice). METHODOLOGY: Following a baseline oral soft tissue examination and scoring of extrinsic tooth Stain and tooth shade, qualifying adult male and female subjects from the Harrisburg, Pennsylvania area were randomized into either the Test or Positive Control Dentifrice group. The two groups were balanced for gender, extrinsic tooth Stain, and tooth shade scores. All subjects were provided their assigned dentifrice and a soft-bristled adult toothbrush for home use. Subjects were instructed to brush their teeth for two minutes twice daily (morning and evening) using only the dentifrice provided, and to refrain from using any other oral hygiene products for the entire six weeks of the study. There were no restrictions regarding diet or smoking habits during the course of the study. Oral soft tissue, extrinsic tooth Stain, and tooth shade assessments for each subject were repeated after two and six weeks of product use. All statistical tests were two sided and employed a level of significance of alpha = 0.05. RESULTS: Fifty-six (56) subjects complied with the protocol and completed the entire study. Compared to baseline at both the two- and six-week examinations, the Test Dentifrice group had statistically significant reductions in extrinsic tooth Stain area and intensity, and statistically significant mean shade rank reductions, with a six-week reduction of 4.81. In contrast, at six weeks, the Positive Control dentifrice had a statistically significant increase in tooth Stain area, a non-significant increase in tooth Stain intensity, and a statistically significant mean 1.40 shade rank score reduction. At both the two- and six-week examinations, the Test Dentifrice group had statistically significantly lighter tooth shades and statistically significantly lower levels of extrinsic tooth Stain area and intensity than the Positive Control Dentifrice group. CONCLUSION: A new whitening dentifrice delivering 1.0% hydrogen peroxide, 0.243% sodium fluoride, and sodium tripolyphosphate in a high-cleaning silica base has significant efficacy in tooth whitening and extrinsic Stain Removal, and provides a statistically significantly greater level of efficacy for both tooth whitening and extrinsic tooth Stain Removal than the commercially available Positive Control Dentifrice.
Yiming Li - One of the best experts on this subject based on the ideXlab platform.
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Stain Removal and whitening by baking soda dentifrice: A review of literature.
Journal of the American Dental Association (1939), 2020Co-Authors: Yiming LiAbstract:Tooth discoloration may be caused by intrinsic or extrinsic Stains or a combination of both. There are 2 major approaches to removing the Stains, including the chemical mechanism using peroxides for tooth bleaching and the mechanical mechanism using abrasives in prophylactic pastes and dentifrices to remove Stains, resulting in a whitening effect. Attempts have also been made to add a low concentration of peroxides to dentifrices to enhance their abrasive cleaning to remove tooth Stains. This article provides a review of both in vitro and clinical studies on Stain Removal and whitening effect of dentifrices containing sodium bicarbonate (baking soda). In recent years, whitening dentifrices have become popular because of little additional effort for use, ease of availability, low cost, and accumulated evidence of clinical efficacy and safety in the literature. Advances in research and technology have led to innovative formulations of dentifrices using baking soda as the sole abrasive or a component of an abrasive system. Baking soda is biologically compatible with acid-buffering capacities, antibacterial at high concentrations, and has a relatively lower abrasivity. The evidence available in the literature indicates that baking soda-based dentifrices are effective and safe for tooth Stain Removal and consequently whitening. A number of clinical studies have also shown that baking soda-based dentifrices are more effective in Stain Removal and whitening than some non-baking soda-containing dentifrices with a higher abrasivity. So far, research efforts have mainly focused on Stain Removal and tooth-whitening efficacy and clinical safety of baking soda dentifrices used with manual toothbrushes, with only a few studies investigating their effects using powered toothbrushes, for which further research is encouraged. As part of a daily oral hygiene practice, baking soda-based dentifrice is a desirable, alternative or additional measure for tooth Stain Removal and whitening. Copyright © 2017 American Dental Association. Published by Elsevier Inc. All rights reserved.
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Stain Removal and whitening by baking soda dentifrice a review of literature
Journal of the American Dental Association, 2017Co-Authors: Yiming LiAbstract:Abstract Background Tooth discoloration may be caused by intrinsic or extrinsic Stains or a combination of both. There are 2 major approaches to removing the Stains, including the chemical mechanism using peroxides for tooth bleaching and the mechanical mechanism using abrasives in prophylactic pastes and dentifrices to remove Stains, resulting in a whitening effect. Attempts have also been made to add a low concentration of peroxides to dentifrices to enhance their abrasive cleaning to remove tooth Stains. Types of Studies Reviewed This article provides a review of both in vitro and clinical studies on Stain Removal and whitening effect of dentifrices containing sodium bicarbonate (baking soda). In recent years, whitening dentifrices have become popular because of little additional effort for use, ease of availability, low cost, and accumulated evidence of clinical efficacy and safety in the literature. Advances in research and technology have led to innovative formulations of dentifrices using baking soda as the sole abrasive or a component of an abrasive system. Baking soda is biologically compatible with acid-buffering capacities, antibacterial at high concentrations, and has a relatively lower abrasivity. Conclusions The evidence available in the literature indicates that baking soda–based dentifrices are effective and safe for tooth Stain Removal and consequently whitening. A number of clinical studies have also shown that baking soda–based dentifrices are more effective in Stain Removal and whitening than some non–baking soda—containing dentifrices with a higher abrasivity. So far, research efforts have mainly focused on Stain Removal and tooth-whitening efficacy and clinical safety of baking soda dentifrices used with manual toothbrushes, with only a few studies investigating their effects using powered toothbrushes, for which further research is encouraged. Practical Implications As part of a daily oral hygiene practice, baking soda–based dentifrice is a desirable, alternative or additional measure for tooth Stain Removal and whitening.
M Addy - One of the best experts on this subject based on the ideXlab platform.
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abrasion and Stain Removal by different manual toothbrushes and brush actions studies in vitro
Journal of Clinical Periodontology, 2001Co-Authors: D Dyer, Emma L Macdonald, R G Newcombe, C Scratcher, M AddyAbstract:Background and aims: A limited amount of data using flat trim multitufted toothbrushes shows that abrasion of substrate surfaces by a standard toothpaste varies dependent on filament stiffness and configuration; soft brushes producing the most abrasion. The aims of these studies in vitro were to assess toothpaste abrasion of acrylic and Stain Removal by 5 proprietary medium toothbrushes with different head filament arrangements, and a prototype brush with rectangular filaments. The prototype brush had a medium texture in the long axis and soft texture at right angles to the long axis. Material and method: Optically clear acrylic was used as the substrate for abrasion by a standard toothpaste. Loss of substrate was determined by profilometry after 5000, 10 000, 15 000 and 20 000 linear or rotary brushing actions. Stain Removal was determined spectrophotometrically from optically clear acrylic specimens Stained by chlorhexidine tea soaking sequences. Stained specimens were brushed with water using linear or rotary actions and measurements taken every 10 s to 60 s. Results: Abrasion was progressive with increasing strokes and the pattern for each brush and brush action was to a first approximation linear. Overall, abrasion was significantly greater with linear compared to rotary action. Also overall brushes differed in the abrasion produced with both actions and particularly at greater exposure times. Within brush differences for the two motions were all significant by 20 000 strokes except for the prototype brush. Stain Removal was progressive over time with each brush but the pattern was non-linear. For the proprietary brushes the rotary motion removed less Stain. For the prototype brush more Stain was removed with the rotary action. Overall brushes differed significantly in Stain Removal within each motion and for each motion most differences between the proprietary and prototype brushes reached significance. Conclusions: The differences between brushes for both abrasion and Stain Removal must in large part relate to the filament contact area with the substrate surface. Whilst the model may not be predictive of clinical differences, it could find use to establish minimum criteria for toothbrush action.
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the chemical Stain Removal properties of whitening toothpaste products studies in vitro
British Dental Journal, 2000Co-Authors: N Sharif, Emma L Macdonald, John G Hughes, R G Newcombe, M AddyAbstract:Background A considerable number of toothpastes are available as tooth whitening products. Most appear to contain ingredients that might remove extrinsic Stains rather than change natural tooth colour. Extrinsic Stain Removal could be achieved by physical or chemical means. Aim The purpose of this study was to measure the chemical Stain Removal properties of a range of whitening toothpaste products and experimental formulations using a standardised method in vitro. Materials and method 5 separate studies were conducted involving a total of 39 agents of which 28 were whitening products, 7 were experimental formulations, 2 were oxidising mouthrinses used as positive controls, 1 was a popular fluoride toothpaste product as a benchmark control, and 1 was water as the negative control. The formulations and controls varied in each study. The Stain model was saliva/chlorhexidine/tea Stain developed on optically clear acrylic to an optical density of at least 2.0. Groups of Stained specimens were exposed to standard slurries or solutions of each test agent for 1 minute periods up to 5 minutes. Optical density readings were taken at each 1 minute time point. Analyses were based on per cent Stain remaining after 5 minutes and time to 75% Stain remaining. Results 3 toothpaste products achieved 100% Stain Removal by 5 minutes; 2 of these in 3 out of 4 studies in which they were used. 4 experimental formulations also achieved 100% Stain Removal. In general agents with high total Stain Removal also had short times to 75% Stain remaining. The majority of agents tested had low total chemical Stain Removal and prolonged times to 75% Stain remaining. A few agents were little different from water and several similar in effect to the conventional fluoride toothpaste. This method in vitro tests agents under the best case scenario conditions for chemical Stain Removal. Conclusion Only a small number of the whitening toothpaste products have good chemical Stain Removal potential; the majority are unlikely to achieve their claimed benefits through chemical Stain Removal. There is clearly a need for further data on the actual effects of such products using both methods in vitro and particularly in vivo or in situ.
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the use of acrylic to compare the abrasivitand Stain Removal properties of toothpastes
Clinical Materials, 1991Co-Authors: M Addy, Simon Goodfield, Alan HarrisonAbstract:Abstract The aim of this study was to compare the abrasivity and Stain Removal properties of toothpastes using acrylic. Acrylic blocks were exposed to 2·5 × 104 and 5·0 × 104 brush strokes with a number of toothpastes. Abrasion measurements were made using a surfometer. Percentage Stain Removal with time was recorded from specimens Stained by chlorhexidine and tea soaking. Pre- and post-treatment optical densities were recorded spectrophotometrically. Products were applied to specimens as slurries alone or with brushing. Depth of abrasion was ⩽ 10 μm for most toothpastes (5 × 104 strokes). For two desensitising toothpastes the depth reached > 40 μm. Stain Removal was dependant on the duration of brushing, but at 1 min., ranged from 97% to 50% for toothpastes and 45% for a brush and water. Slurries of toothpaste also variably removed Stain; effects at 1 min. ranged from 90% to levels similar to water, namely 5%. It is concluded that the model is a simple and reproducible method to compare oral hygiene products and allows chemical Stain Removal properties to be ascertained and divorced from abrasion and chemical erosion.
Geza T. Terezhalmy - One of the best experts on this subject based on the ideXlab platform.
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Clinical assessment of extrinsic Stain Removal efficacy with a new Pulsonic toothbrush.
The Journal of clinical dentistry, 2020Co-Authors: Geza T. Terezhalmy, Tao He, Patricia A Walters, Julie Grender, Aaron R BiesbrockAbstract:OBJECTIVE: To assess the extrinsic Stain Removal benefit of two different power toothbrushes: an experimental Oral-B Pulsonic rechargeable toothbrush and a positive control Sonicare FlexCare toothbrush. METHODS: This was a randomized, positive-controlled, examiner-blind, two-treatment, parallel group, two-week study. A Lobene Stain index was performed at baseline on the facial surfaces of the anterior teeth. Subjects were randomized to one of two treatment groups: Pulsonic or FlexCare. Both groups were assigned the same fluoride dentifrice, and were instructed to brush their teeth twice per day for two minutes with the assigned toothbrush and dentifrice in front of a mirror. A further Lobene Stain index was performed following two weeks of brushing. RESULTS: A highly significant reduction (p 0.1). CONCLUSION: Both the experimental Pulsonic and the positive control FlexCare power toothbrushes showed highly effective Stain Removal efficacy relative to baseline following two weeks of brushing. Stain Removal efficacy did not differ significantly between brushes.
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Stain Removal Assessment of Two Manual Toothbrushes with an Interproximal Tooth Stain Index.
The Journal of clinical dentistry, 2020Co-Authors: Svetlana Farrell, Geza T. Terezhalmy, Julie Grender, Luis ArchilaAbstract:OBJECTIVE: To assess a newly developed index to measure interproximal Stain and evaluate the Stain Removal efficacy of two commercially available manual toothbrushes. METHODS: This was a randomized, examiner-blind, parallel-group, two-treatment clinical trial of two weeks' duration. Subjects qualified for the study if they had an average Modified Lobene Stain Index of ≥ 1.5 from two anterior teeth. At baseline, subjects brushed in front of a mirror for one minute under supervision. All subjects were provided with a standard 0.243% sodium fluoride dentifrice and were randomly assigned either an Oral-B Pulsar manual brush (OBP) or a Colgate Whitening manual brush (CW) to use for two weeks. Stain was reassessed after two weeks of product use. Stain measurements were conducted using the Modified Lobene Stain Index and the new Interproximal Modified Lobene Stain Index, which allows for assessment of Stain in hard-to-reach areas using the same area and intensity scales as the Modified Lobene Stain Index. RESULTS: Use of the two manual brushes resulted in statistically significant reductions in surface Stain relative to baseline after two weeks of use. Median Stain reductions were 78% and 60% for the OBP and CW, respectively, as measured by the Modified Lobene Stain Index. The mean changes in the composite scores from baseline to week two were 1.85 and 1.57 for the two treatment groups, respectively. Statistically significant reductions from baseline were also found for the intensity and extent of Stain measures (p < 0.001). Similar trends were found using the new Interproximal Modified Lobene Index. Composite median Stain Removal percentages versus baseline were 88% and 73% for the OBP and CW groups, respectively (p < 0.001). For the interproximal sites, a median Stain Removal of 92% was observed with the OBP brush and 83% reduction with the CW brush. For the gingival sites, the median Stain Removal percentages were 83% and 50%, respectively For the body region, a median Stain Removal of 100% was found for both treatment groups. No statistically significant differences were found between the two groups for the mean composite scores for either index. CONCLUSION: Both manual brushes showed effective Stain Removal, including interproximal hard-to-reach sites. The Interproximal Modified Lobene Stain Index gave clinically relevant results consistent with the traditional Modified Lobene Stain Index, while allowing assessment of interproximal regions.
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A Randomized Controlled Clinical Trial to Evaluate Extrinsic Stain Removal of a Whitening Dentifrice.
The Journal of clinical dentistry, 2016Co-Authors: Geza T. Terezhalmy, Tao He, Mary Kay Anastasia, Rachelle EusebioAbstract:OBJECTIVES: To evaluate the extrinsic Stain Removal efficacy of a new whitening dentifrice containing sodium hexametaphosphate (SHMP) over a two-week period. METHODS: This study used a controlled and randomized, examiner-blind, single-center, two-treatment, parallel group design. Subjects with visible extrinsic dental Stain on facial surfaces of their anterior teeth, and meeting all study criteria, were entered into the trial. The test group received the whitening dentifrice with sodium fluoride and SHMP and an ADA reference soft manual toothbrush. Subjects in the control group received a dental prophylaxis after the initial examination at Baseline and were instructed to use their usual oral hygiene products at home. Subjects returned at Day 3 and Week 2 for re-evaluation of extrinsic dental Stain. Extrinsic Stain was measured using the Interproximal Modified Lobene (IML) Stain Index; safety was assessed based on clinical examination. RESULTS: Fifty subjects (mean age 32.0 years) completed the study, with 25 in each group. Statistically significant reductions in composite Stain for whole tooth, as well as interproximal, gingival, and body surfaces were observed for both groups at Day 3 and Week 2 (p 0.3). At Day 3, median percent reductions in composite IML Stain from Baseline were 98% for the prophylaxis group and 100% for the test dentifrice group. At Week 2, median percent reductions in composite IML Stain were 100% compared to Baseline for both groups. No adverse events were reported for either group. CONCLUSIONS: The whitening dentifrice demonstrated a statistically significant reduction in IML Stain after three days and two weeks of use relative to baseline. Stain reduction with the toothpaste was comparable to a dental prophylaxis.
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A clinical evaluation of extrinsic Stain Removal: a rotation-oscillation power toothbrush versus a dental prophylaxis.
The journal of contemporary dental practice, 2008Co-Authors: Geza T. Terezhalmy, Patricia A Walters, Julie Grender, Robert D. Bartizek, Aaron R BiesbrockAbstract:AIM: To assess extrinsic Stain Removal efficacy of a power toothbrush and a dental prophylaxis followed by the use of a standardized American Dental Association (ADA) reference manual toothbrush. METHODS AND MATERIALS: This was a randomized, positive-controlled, examiner-blind, parallel group, two-week study. A Lobene Stain examination was performed at baseline. Subjects were randomized to one of two treatment groups: Group 1: Oral-B Vitality Pro White power toothbrush or Group 2: Subjects receiving a dental prophylaxis then using a standardized ADA reference manual toothbrush. Subjects were instructed to brush their teeth with the assigned toothbrush and a fluoride dentifrice in front of a mirror twice per day for 2 minutes. Stain was reassessed following 2 weeks of brushing. RESULTS: A significant reduction (p 0.1). CONCLUSIONS: The Oral-B Vitality Pro White power toothbrush showed effective Stain Removal at a level similar to receiving an oral prophylaxis followed by the use of an ADA reference manual toothbrush. CLINICAL SIGNIFICANCE: In this small study the Oral-B Vitality Pro White power toothbrush achieved statistically significant Stain Removal between dental visits.
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clinical evaluation of the Stain Removal efficacy of a novel stannous fluoride and sodium hexametaphosphate dentifrice
American Journal of Dentistry, 2007Co-Authors: Geza T. Terezhalmy, Robert A Baker, Eros Chaves, Samer A Bsoul, Tao HeAbstract:PURPOSE: Recently, sodium hexametaphosphate has been introduced in dentifrice formulations to aid in the control of extrinsic Stain. Two independent studies were conducted to evaluate the Stain Removal efficacy of a novel 0.454% stannous fluoride and sodium hexametaphosphate dentifrice (Crest Pro-Health) relative to a positive control whitening dentifrice (Colgate Total + Whitening) over a 2-week period in a subject population with pre-existing natural extrinsic Stain. METHODS: These studies were randomized, positive-controlled, parallel groups, double-blind, 2-week trials. Each study involved approximately 30 healthy adults with visible Stain of the facial surfaces of the 12 anterior teeth. After baseline examination, subjects were randomly assigned to a treatment and instructed to brush unsupervised with the assigned dentifrice at least twice daily as they normally do. Efficacy was evaluated by modified Lobene examination on anterior teeth at baseline and end-of treatment (Week 2). RESULTS: 59 subjects, 29 in Study 1 and 30 in Study 2, were evaluable and included in the Week 2 analyses. Subjects ranged from 21-68 years of age. In each study, the positive control dentifrice statistically significantly (P 0.70 in each study). Both dentifrices were well tolerated. No subject discontinued treatment due to an adverse event.
Anthony R Volpe - One of the best experts on this subject based on the ideXlab platform.
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A six-week clinical study to compare the Stain Removal efficacy of three dentifrices.
The Journal of clinical dentistry, 2020Co-Authors: Salim Nathoo, Margaret Petrone, William Devizio, Chaknis P, Anthony R VolpeAbstract:: The objective of this double-blind clinical study was to compare the tooth whitening efficacy (Stain Removal) of a new commercially available tooth whitening dentifrice (Colgate Total Plus Whitening Toothpaste) containing 0.2% triclosan and 3.0% PVM/MA copolymer in a 0.243% sodium fluoride/high cleaning silica base, with that of two commercially available dentifrices, Crest Multi-Care Advanced Cleaning Toothpaste and Colgate Winterfresh Gel Fluoride Toothpaste. Following a baseline examination to assess extrinsic tooth Stain, qualifying adult male and female subjects were randomized into three treatment groups which were balanced for gender, age and level of extrinsic tooth Stain. Subjects were asked to brush their teeth twice (morning and evening) for one minute with their assigned dentifrice using a soft-bristled toothbrush. Examinations for extrinsic tooth Stain were repeated after six weeks' use of the study dentifrices. One-hundred and twenty-three (123) subjects complied with the protocol and completed the study. At the six-week examination, subjects assigned to the Colgate Total Plus Whitening Toothpaste treatment group exhibited statistically significant reductions in extrinsic tooth Stain area and extrinsic tooth Stain intensity relative to those subjects assigned to the Crest Multi-Care Advanced Cleaning Toothpaste and the Colgate Winterfresh Gel Fluoride Toothpaste.
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Clinical comparison of the Stain-Removal efficacy of a novel liquid whitening gel containing 18% carbamide peroxide and a commercially available whitening dentifrice.
Compendium of continuing education in dentistry (Jamesburg N.J. : 1995), 2020Co-Authors: Farid Ayad, William Devizio, Martin Giniger, Howard M Proskin, John P Curtis, Peter P Santarpia, Bernal Stewart, Margaret Petrone, Anthony R VolpeAbstract:The objective of this examiner-blind clinical study was to compare the extrinsic tooth-Stain Removal efficacy of a novel, nontray, "paint-on" liquid whitening gel containing 18% carbamide peroxide (Colgate Simply White Clear Whitening Gel) with a commercially available whitening dentifrice. After a baseline examination for extrinsic tooth Stain, qualifying adult men and women from Canada were randomized into two treatment groups balanced for age, gender, and level of extrinsic tooth Stain. Subjects were instructed to brush their teeth twice daily (morning and evening) for 1 minute with their assigned dentifrice (Group 1: nonwhitening dentifrice; Group 2: whitening dentifrice). The subjects in Group 1 also were instructed to use the paint-on whitening gel for 30 minutes twice daily. Examinations for extrinsic tooth Stain were repeated after 2 and 3 weeks. Ninety-seven subjects complied with the protocol and completed the entire study. At both the 2- and 3-week examinations, subjects assigned to the liquid whitening gel-treatment group exhibited statistically significant reductions in extrinsic tooth Stain (P < .05) with respect to Stain area (22.7% reduction at 3 weeks), Stain intensity (26.3% reduction at 3 weeks), and overall Stain Removal (32% reduction at 3 weeks) compared with the commercially available whitening dentifrice group. Thus, the results of the examiner-blind clinical study support the conclusion that Colgate Simply White Clear Whitening Gel provides a significantly greater level of extrinsic tooth-Stain Removal efficacy than a commercially available whitening dentifrice.
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Laboratory and clinical Stain Removal evaluations of two tartar control dentifrices.
The Journal of clinical dentistry, 1995Co-Authors: Samuel L Yankell, Emling Rc, Michael Prencipe, Kedar N. Rustogi, Anthony R VolpeAbstract:: The purpose of this research was to evaluate Colgate original Tartar Control dentifrice (TC) and new Colgate Micro Cleansing Tartar Control (MCTC) dentifrice in a laboratory and clinical study for their ability to remove induced Stain. In the laboratory study, polished and etched bovine enamel specimens were Stained for 4 days with a coffee, tea, and mucin, Sarcina lutea tartox culture in trypticase soy broth. Sixteen specimens were then brushed for 200 strokes with a sodium carboxymethyl cellulose solution to remove loose Stain, and then brushed for 300 strokes with a 1:1 toothpaste slurry. Tooth color was measured by reflectance with the CLE L*a*b* scale. The calculated Stain Removal, 37% for MCTC and 24% for TC, was significantly different (p
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Clinical study to assess the Stain Removal efficacy of two tartar control dentifrices and a low abrasive dentifrice.
The Journal of clinical dentistry, 1994Co-Authors: Samuel L Yankell, Emling Rc, Michael Prencipe, Kedar N. Rustogi, Anthony R VolpeAbstract:: Significant differences in Stain Removal have been demonstrated in a laboratory study comparing two tartar control dentifrices: Platinum, containing 1.3% soluble pyrophosphate and 1.5% of a copolymer, and Crest Tartar Control, containing 5% soluble pyrophosphate. The purpose of this clinical study was to evaluate the same tartar control dentifrices, and a low abrasive dentifrice for their ability to reduce Peridex-induced Stain. Eighty-five subjects were given Peridex (0.12% chlorhexidine digluconate) and a low abrasive dentifrice for 4 weeks. The 76 subjects with sufficient Stain were stratified using the Lobene index on buccal and lingual surfaces of anterior teeth, and randomly assigned one of the three dentifrices for 8 weeks. At the end of the study, total Stain evaluations were significantly lower in the Platinum dentifrice group (mean 0.84) compared to both Crest Tartar Control dentifrice (1.08) and the low abrasive dentifrice (1.09) at p
