The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
Eun Chang Choi - One of the best experts on this subject based on the ideXlab platform.
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perivascular Submandibular Lymph Node metastasis in squamous cell carcinoma of the tongue and floor of mouth
Ejso, 2004Co-Authors: Eun Chang ChoiAbstract:Abstract Aims. The goal of this study was to investigate the incidence of occult metastasis in perivascular Lymph Node and nodal recurrence in these nodal pads in squamous cell carcinoma (SCC) of the tongue and floor of mouth. Methods. We performed a prospective analysis of the incidence of an occult metastasis in the perivascular Lymph Nodes in 55 patients (41 with an oral tongue carcinoma and 14 with a mouth floor carcinoma) who underwent an elective supraomohyoid neck dissection (SOHND) for SCC of the tongue and floor of mouth, from 1997 to 2002. 99 SOHND procedures were performed as follows: 72 in tongue carcinomas and 27 in the mouth floor carcinomas. Result. Clinically occult, but pathologically positive perivascular Lymph Nodes occurred in four of 72 of the tongue carcinomas and two of 27 of the mouth floor carcinomas. The incidence of the regional recurrence at level I was three of 45. Conclusions. This preliminary report reveals a small incidence of perivascular Lymph-Node metastases and the infrequent nodal recurrence in this area after SOHND in early-staged tongue and floor of mouth SCC.
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Perivascular–Submandibular Lymph Node metastasis in squamous cell carcinoma of the tongue and floor of mouth
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2004Co-Authors: Yongjun Lim, J.w Kim, Yoon Woo Koh, Kyung-rae Kim, Hyung Jun Kim, Kyoungsub Kim, Eun Chang ChoiAbstract:Abstract Aims. The goal of this study was to investigate the incidence of occult metastasis in perivascular Lymph Node and nodal recurrence in these nodal pads in squamous cell carcinoma (SCC) of the tongue and floor of mouth. Methods. We performed a prospective analysis of the incidence of an occult metastasis in the perivascular Lymph Nodes in 55 patients (41 with an oral tongue carcinoma and 14 with a mouth floor carcinoma) who underwent an elective supraomohyoid neck dissection (SOHND) for SCC of the tongue and floor of mouth, from 1997 to 2002. 99 SOHND procedures were performed as follows: 72 in tongue carcinomas and 27 in the mouth floor carcinomas. Result. Clinically occult, but pathologically positive perivascular Lymph Nodes occurred in four of 72 of the tongue carcinomas and two of 27 of the mouth floor carcinomas. The incidence of the regional recurrence at level I was three of 45. Conclusions. This preliminary report reveals a small incidence of perivascular Lymph-Node metastases and the infrequent nodal recurrence in this area after SOHND in early-staged tongue and floor of mouth SCC.
Kui Zhao - One of the best experts on this subject based on the ideXlab platform.
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inability of pet ct to identify a primary sinonasal inverted papilloma with squamous cell carcinoma in a patient with a Submandibular Lymph Node metastasis a case report
Oncology Letters, 2015Co-Authors: Si Cong Zhang, Lin Wei, Shui Hong Zhou, Kui ZhaoAbstract:The present study describes the first reported case of a sinonasal inverted papilloma (IP) with squamous cell carcinoma (SCC) that presented as a cancer of unknown primary in the English-language literature. In July 2010, a 66-year old male presented with a 6-month history of a painless, progressive mass in the right Submandibular region. Physical examination revealed a 3×4-cm smooth, non-tender mass and subsequently, excision of the right Submandibular gland was performed. Post-operative pathological examination indicated poorly-differentiated SCC of the Submandibular Lymph Node. Positron-emission tomography/computed tomography (PET/CT) was unable to identify the primary tumour site in this case, and 14 months later the patient presented with nasal obstruction, leading to the diagnosis of right sinonasal IP with coexistent SCC. The patient received pre-operative radiotherapy, a right total maxillectomy and post-operative radiotherapy. However, the patient succumbed to a distant metastasis 37 months after the initial presentation. (18)F-fluorodeoxyglucose uptake on PET/CT may be not a reliable predictor of malignancy in sinonasal IPs. Therefore, we suggest emphasis of the use of multiple biopsies for suspected sinonasal IPs in order to improve diagnostic accuracy.
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Inability of PET/CT to identify a primary sinonasal inverted papilloma with squamous cell carcinoma in a patient with a Submandibular Lymph Node metastasis: A case report.
Oncology letters, 2015Co-Authors: Si‑cong Zhang, Lin Wei, Shui‑hong Zhou, Kui ZhaoAbstract:The present study describes the first reported case of a sinonasal inverted papilloma (IP) with squamous cell carcinoma (SCC) that presented as a cancer of unknown primary in the English-language literature. In July 2010, a 66-year old male presented with a 6-month history of a painless, progressive mass in the right Submandibular region. Physical examination revealed a 3×4-cm smooth, non-tender mass and subsequently, excision of the right Submandibular gland was performed. Post-operative pathological examination indicated poorly-differentiated SCC of the Submandibular Lymph Node. Positron-emission tomography/computed tomography (PET/CT) was unable to identify the primary tumour site in this case, and 14 months later the patient presented with nasal obstruction, leading to the diagnosis of right sinonasal IP with coexistent SCC. The patient received pre-operative radiotherapy, a right total maxillectomy and post-operative radiotherapy. However, the patient succumbed to a distant metastasis 37 months after the initial presentation. (18)F-fluorodeoxyglucose uptake on PET/CT may be not a reliable predictor of malignancy in sinonasal IPs. Therefore, we suggest emphasis of the use of multiple biopsies for suspected sinonasal IPs in order to improve diagnostic accuracy.
Roberta Riboni - One of the best experts on this subject based on the ideXlab platform.
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Lymph Node reticulum cell neoplasm with progression into cytokeratin-positive interstitial reticulum cell (CIRC) sarcoma: a case study.
Histopathology, 2003Co-Authors: Marco Lucioni, Emanuela Boveri, R. Rosso, Marco Benazzo, Vittorio Necchi, M Danova, Paolo Incardona, Carla Franco, Alessandra Viglio, Roberta RiboniAbstract:Aims: To detail on sequential biopsies the morphological and immunohistochemical features of a case of primary Lymph nodal fibroblastic reticulum cell (FBRC) tumour which progressed into a clinically aggressive cytokeratin-positive interstitial reticulum cell (CIRC) sarcoma. Methods and results: A 70-year-old female underwent surgical excision of an enlarged Submandibular Lymph Node. The nodal architecture was effaced by a neoplastic proliferation of medium to large cells, round to oval to spindle in shape, growing in a storiform pattern. The tumour stained for vimentin, CD68, factor XIIIa, α1-antitrypsin, fascin and actin. Dendritic and endothelial cell markers were negative. A diagnosis of FBRC tumour was made by combining pathological and clinical data. The patient received no therapy but 5 months later the tumour relapsed, exhibiting a deceptively pleomorphic cytology, phenotypic changes (strong cytokeratin positivity), intense p53 expression and aggressive clinical course with fatal outcome. In-situ hybridization for Epstein–Barr virus was negative. Conclusions: We speculate that the morphological changes and p53 expression of the relapsing neoplasm might reflect tumour cell dedifferentiation, in keeping with the aggressive clinical course. The intense p53 expression suggests that this oncoprotein might also play a role in reticulum cell tumorigenesis.
J. Landeyro - One of the best experts on this subject based on the ideXlab platform.
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Gingival and Submandibular Lymph Node metastasis of sigmoid colon adenocarcinoma
Journal of Clinical and Experimental Dentistry, 2010Co-Authors: A Raventós, J Mommsen, Analia Elguezabal, M. Gené, L Boutayed, J. LandeyroAbstract:Introduction: Metastatic tumors of oral and maxillofacial region compromise 1% of all malignant oral neoplasms. Most commonly affect the jaw bone and less commonly intraoral soft tissues. They originate mainly from primary tumors of lung, breast, colon-rectum, prostate and kidney. Case report: a 77 years old man with history of sigmoid colon adenocarcinoma and liver metastasis. Two years later of being free of disease, he presented with Submandibular Lymphadenopathy and a gingival mass in right upper jaw. Fine needle aspiration of the Node and biopsy of the gingival mass were performed. The cytological smears showed cohesive cell groups on a necrotic background. Biopsy examination showed subepithelial infiltration by neoplasm of glandular pattern with immunoreactivity for keratin 20 and carcinoembryonic antigen. A definitive diagnosis of Node and oral metastases of colon adenocar cinoma was made. Discussion: Metastases in the oral and maxillofacial region are very uncommon and usually represent an advanced stage and disseminated disease. They present non specific radiologic and clinical features so it is imperative to reach a definitive diagnosis the cytological/histological examination. Because of its rarity, the diagnosis of metastases in the oral region are a challenging, both to the clinician and to the pathologist, in recognising that a lesion is metastasic and in determining the site of origin.
Stuart H. Goldberg - One of the best experts on this subject based on the ideXlab platform.
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Metastatic basal cell carcinoma of the eyelid.
Archives of Ophthalmology, 1996Co-Authors: Stuart H. GoldbergAbstract:I read with great interest the clinicopathologic report by Dr Davies et al, 1 regarding metastatic basal cell carcinoma of the eyelid. The authors indicated that, to their knowledge, their reported case of presumed preauricular soft tissue metastasis of basal cell carcinoma is unique in the ophthalmic literature in the United States and Europe. I would like to draw the authors' attention to a recent report in the ophthalmic literature including two cases of metastatic basal cell carcinoma. In 1989, Bartley et al 2 reported a series of 102 orbital exenterations performed over a 20-year period at the Mayo Clinic. Of the 100 patients with neoplastic disorders, two had metastatic basal cell carcinoma. One patient was found at autopsy to have metastasis to the right middle lobe of the lung and the second patient developed a Submandibular Lymph Node metastasis 9 months after orbital exenteration. These two cases of remote
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Metastatic basal cell carcinoma of the eyelid.
Archives of Ophthalmology, 1996Co-Authors: Stuart H. GoldbergAbstract:I read with great interest the clinicopathologic report by Dr Davies et al, 1 regarding metastatic basal cell carcinoma of the eyelid. The authors indicated that, to their knowledge, their reported case of presumed preauricular soft tissue metastasis of basal cell carcinoma is unique in the ophthalmic literature in the United States and Europe. I would like to draw the authors' attention to a recent report in the ophthalmic literature including two cases of metastatic basal cell carcinoma. In 1989, Bartley et al 2 reported a series of 102 orbital exenterations performed over a 20-year period at the Mayo Clinic. Of the 100 patients with neoplastic disorders, two had metastatic basal cell carcinoma. One patient was found at autopsy to have metastasis to the right middle lobe of the lung and the second patient developed a Submandibular Lymph Node metastasis 9 months after orbital exenteration. These two cases of remote
