The Experts below are selected from a list of 690 Experts worldwide ranked by ideXlab platform
Olivier Witschger - One of the best experts on this subject based on the ideXlab platform.
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characterization of aerosols generated from nine nanomaterial powders reliability with regard to in vivo inhalation toxicology studies
Journal of Nanoparticle Research, 2018Co-Authors: Soleiman Bourrous, F Gaielevrel, Olivier WitschgerAbstract:In experimental toxicology, when simulating human exposure to aerosols in the working environment, inhalation is the route of administration of choice for evaluating the toxicity of a given material (in aerosol form) in animals. In this context, this work aimed to contribute to the establishment of recommendations concerning the characterization of aerosol tests in inhalation toxicology studies. In particular, the work consisted of experimentally characterizing test aerosols using a given generation method to be used for inhalation toxicology studies. Nine nanomaterial powders have been investigated (four types of TiO2, two types of SiO2, ZnO, CeO, and BaSO4). The aerosols produced cover the particle size range from a few tens of nanometers up to several micrometers and are mainly composed of aggregates and/or agglomerates. The work carried out shows that generation and characterization of test aerosols for inhalation toxicology studies is a complex but essential element of inhalation studies, for which the conditions required (stability, repeatability, level of concentration) are sometimes difficult to obtain. Moreover, this study highlights the necessity to carry out preliminary tests to ascertain the performances of the chosen devices and their suitability for inhalation toxicology.
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Characterization of aerosols generated from nine nanomaterial powders reliability with regard to in vivo inhalation toxicology studies
Journal of Nanoparticle Research, 2018Co-Authors: Soleiman Bourrous, François Gaie-levrel, Olivier WitschgerAbstract:In experimental toxicology, when simulating human exposure to aerosols in the working environment, inhalation is the route of administration of choice for evaluating the toxicity of a given material (in aerosol form) in animals. In this context, this work aimed to contribute to the establishment of recommendations concerning the characterization of aerosol tests in inhalation toxicology studies. In particular, the work consisted of experimentally characterizing test aerosols using a given generation method to be used for inhalation toxicology studies. Nine nanomaterial powders have been investigated (four types of TiO2, two types of SiO2, ZnO, CeO, and BaSO4). The aerosols produced cover the particle size range from a few tens of nanometers up to several micrometers and are mainly composed of aggregates and/or agglomerates. The work carried out shows that generation and characterization of test aerosols for inhalation toxicology studies is a complex but essential element of inhalation studies, for which the conditions required (stability, repeatability, level of concentration) are sometimes difficult to obtain. Moreover, this study highlights the necessity to carry out preliminary tests to ascertain the performances of the chosen devices and their suitability for inhalation toxicology. © 2018, Springer Nature B.V.
Muzur Amir - One of the best experts on this subject based on the ideXlab platform.
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ZVONIMIR MARETIĆ (1921. – 1989.): POVIJEST OTKRIĆA PRVOGA EUROPSKOG ANTILATRODEKTIČKOG SERUMA I NJEGOVA PRIREĐIVAČA U POVODU 30. GODIŠNJICE NJEGOVE SMRTI
'Croatia Scientific Society for the History of Health Culture', 2019Co-Authors: Buterin Toni, Glažar Bojan, Muzur AmirAbstract:Zvonimir Maretić was the pioneer of the study of venomous animals and plants, toxicology, and tourism medicine. His achievements have been recognized, but insufficiently researched. His work covers a broad range of biomedical sciences: from public health, ecology, and environmental protection, to epidemiology and infectology. Maretić was one of the founding members of the International Society on Toxinology and the Toxicon journal’s first Editorial Board. He was the first in Europe to prepare the antilatrodectic serum and to successfully apply the weever and scorpionfish antiserum on humans. This brief note tries to commemorate the achievements of Maretić, up to now poorly recognized and insufficiently researched.Zvonimir Maretić pionir je proučavanja otrovnih životinja i biljaka, njihove toksikologije te turističke medicine. Njegovo djelo i rad principijelno je cijenjeno, ali slabo istraženo. Djelovao je u širokom području medicine i biomedicinskih znanosti: od javnog zdravstva, ekologije i očuvanja okoliša do zaštite ljudskog zdravlja u obliku epidemiologije i infektologije. Jedan je od članova i osnivača Internacionalnog društva za toksinologiju i član prvoga uredničkog odbora časopisa Toxicon. Prvi je u Europi priredio anilatrodektički serum i na ljudima primijenio serum protiv otrova morskog pauka. Ovaj rad nastoji komemorirati njegova dosad zanemarena i nedovoljno istražena postignuća
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ZVONIMIR MARETIĆ (1921. – 1989.): POVIJEST OTKRIĆA PRVOGA EUROPSKOG ANTILATRODEKTIČKOG SERUMA I NJEGOVA PRIREĐIVAČA U POVODU 30. GODIŠNJICE NJEGOVE SMRTI
'Croatia Scientific Society for the History of Health Culture', 2019Co-Authors: Buterin Toni, Glažar Bojan, Muzur AmirAbstract:Zvonimir Maretic was the pioneer of the study of venomous animals and plants, toxicology, and tourism medicine. His achievements have been recognized, but insufficiently researched. His work covers a broad range of biomedical sciences: from public health, ecology, and environmental protection, to epidemiology and infectology. Maretic was one of the founding members of the International Society on Toxinology and the Toxicon journal's first Editorial Board. He was the first in Europe to prepare the antilatrodectic serum and to successfully apply the weever and scorpionfish antiserum on humans. This brief note tries to commemorate the achievements of Maretic, up to now poorly recognized and insufficiently researched.Zvonimir Maretić pionir je proučavanja otrovnih životinja i biljaka, njihove toksikologije te turističke medicine. Njegovo djelo i rad principijelno je cijenjeno, ali slabo istraženo. Djelovao je u širokom području medicine i biomedicinskih znanosti: od javnog zdravstva, ekologije i očuvanja okoliša do zaštite ljudskog zdravlja u obliku epidemiologije i infektologije. Jedan je od članova i osnivača Internacionalnog društva za toksinologiju i član prvoga uredničkog odbora časopisa To x i c o n . Prvi je u Europi priredio anilatrodektički serum i na ljudima pri - mijenio serum protiv otrova morskog pauka. Ovaj rad nastoji komemorirati njegova dosad zanemarena i nedovoljno istražena postignuća
Soleiman Bourrous - One of the best experts on this subject based on the ideXlab platform.
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characterization of aerosols generated from nine nanomaterial powders reliability with regard to in vivo inhalation toxicology studies
Journal of Nanoparticle Research, 2018Co-Authors: Soleiman Bourrous, F Gaielevrel, Olivier WitschgerAbstract:In experimental toxicology, when simulating human exposure to aerosols in the working environment, inhalation is the route of administration of choice for evaluating the toxicity of a given material (in aerosol form) in animals. In this context, this work aimed to contribute to the establishment of recommendations concerning the characterization of aerosol tests in inhalation toxicology studies. In particular, the work consisted of experimentally characterizing test aerosols using a given generation method to be used for inhalation toxicology studies. Nine nanomaterial powders have been investigated (four types of TiO2, two types of SiO2, ZnO, CeO, and BaSO4). The aerosols produced cover the particle size range from a few tens of nanometers up to several micrometers and are mainly composed of aggregates and/or agglomerates. The work carried out shows that generation and characterization of test aerosols for inhalation toxicology studies is a complex but essential element of inhalation studies, for which the conditions required (stability, repeatability, level of concentration) are sometimes difficult to obtain. Moreover, this study highlights the necessity to carry out preliminary tests to ascertain the performances of the chosen devices and their suitability for inhalation toxicology.
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Characterization of aerosols generated from nine nanomaterial powders reliability with regard to in vivo inhalation toxicology studies
Journal of Nanoparticle Research, 2018Co-Authors: Soleiman Bourrous, François Gaie-levrel, Olivier WitschgerAbstract:In experimental toxicology, when simulating human exposure to aerosols in the working environment, inhalation is the route of administration of choice for evaluating the toxicity of a given material (in aerosol form) in animals. In this context, this work aimed to contribute to the establishment of recommendations concerning the characterization of aerosol tests in inhalation toxicology studies. In particular, the work consisted of experimentally characterizing test aerosols using a given generation method to be used for inhalation toxicology studies. Nine nanomaterial powders have been investigated (four types of TiO2, two types of SiO2, ZnO, CeO, and BaSO4). The aerosols produced cover the particle size range from a few tens of nanometers up to several micrometers and are mainly composed of aggregates and/or agglomerates. The work carried out shows that generation and characterization of test aerosols for inhalation toxicology studies is a complex but essential element of inhalation studies, for which the conditions required (stability, repeatability, level of concentration) are sometimes difficult to obtain. Moreover, this study highlights the necessity to carry out preliminary tests to ascertain the performances of the chosen devices and their suitability for inhalation toxicology. © 2018, Springer Nature B.V.
Shalini Shah - One of the best experts on this subject based on the ideXlab platform.
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Positive Toxicology Results Are Not Associated with Emergency Physicians’ Opioid Prescribing Behavior
'Western Journal of Emergency Medicine', 2021Co-Authors: Jonathan B. Lee, Ghadi Ghanem, Soheil Saadat, Justin Yanuck, Brent Yeung, Bharath Chakravarthy, Ariana Nelson, Shalini ShahAbstract:Introduction: Given the general lack of literature on opioid and naloxone prescribing guidelines for patients with substance use disorder, we aimed to explore how a physician’s behavior and prescribing habits are altered by knowledge of the patient’s concomitant use of psychotropic compounds as evident on urine and serum toxicology screens. Methods: We conducted a retrospective chart review study at a tertiary, academic, Level I trauma center between November 2017–October 2018 that included 358 patients who were discharged from the emergency department (ED) with a diagnosis of fracture, dislocation, or amputation and received an opioid prescription upon discharge. We extracted urine and serum toxicology results, number and amount of prescription opioids upon discharge, and the presence of a naloxone script. Results: The study population was divided into five subgroups that included the following: negative urine and serum toxicology screen; depressants; stimulants; mixed; and no toxicology screens. When comparing the 103 patients in which toxicology screens were obtained to the 255 patients without toxicology screens, we found no statistically significant differences in the total prescribed morphine milligram equivalent (75.0 and 75.0, respectively) or in the number of pills prescribed (15.0 and 13.5, respectively). Notably, none of the 103 patients who had toxicology screens were prescribed naloxone upon discharge. Conclusion: Our study found no association between positive urine toxicology results for psychotropically active substances and the rates of opioid prescribing within a single-center, academic ED. Notably, none of the 103 patients who had toxicology screens were prescribed naloxone upon discharge. More research on the associations between illicit drug use, opioids, and naloxone prescriptions is necessary to help establish guidelines for high-risk patients
Andrew Stolbach - One of the best experts on this subject based on the ideXlab platform.
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acmt and aact position statement preventing occupational fentanyl and fentanyl analog exposure to emergency responders
Clinical Toxicology, 2018Co-Authors: Michael J Moss, Lewis S Nelson, Brandon J Warrick, Charles A Mckay, Pierre Andre Dube, Sophie Gosselin, Robert B Palmer, Andrew StolbachAbstract:The position of the American College of Medical Toxicology (ACMT) and American Academy of Clinical Toxicology (AACT) is as follows:Fentanyl and its analogs are potent opioid receptor agonists, but ...
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impact of online toxicology training on health professionals the global educational toxicology uniting project getup
Clinical Toxicology, 2017Co-Authors: Anselm Wong, Rais Vohra, Andrew H Dawson, Andrew StolbachAbstract:AbstractObjective: The Global Educational Toxicology Uniting Project (GETUP), supported by the American College of Medical Toxicology, links countries with and without toxicology services via distance education with the aim to improve education. Due to the lack of toxicology services in some countries there is a knowledge gap in the management of poisonings. We describe our experience with the worldwide delivery of an online introductory toxicology curriculum to emergency doctors and other health professionals treating poisoned patients.Methods: We delivered a 15-module introductory Internet-based toxicology curriculum to emergency doctors and health professionals, conducted from August to December 2016. This Internet-based curriculum was adapted from one used to teach emergency residents toxicology in the United States. Modules covered themes such as pharmaceutical (n = 8), toxidromes (n = 2) and agrochemicals (n = 5) poisoning. Participants completed pre-test and post-test multiple choice questions (MCQ...
