The Experts below are selected from a list of 12396 Experts worldwide ranked by ideXlab platform
M V Swain - One of the best experts on this subject based on the ideXlab platform.
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micromechanical property recovery of human carious dentin achieved with colloidal nano β Tricalcium Phosphate
Journal of Dental Research, 2008Co-Authors: Yo Shibata, Li Hong He, Takashi Miyazaki, Yu Kataoka, M V SwainAbstract:Reconstitution of carious dentin has been recognized as difficult, because it progresses by loss of collagen polymerization and by demineralization under acidic conditions. Recently, colloidal alkaline nano-calcium Phosphate, prepared by electrical discharge in a buffered physiological saline solution, has been shown to be effective in the formulation of a bone-like biocomposite by simply being mixed with acidic collagen solution. It was hypothesized that colloidal calcium Phosphate was suitable for the reconstitution of carious dentin. Natural caries lesions in dentin from permanent teeth were exposed to colloidal hydroxyapatite and β-Tricalcium Phosphate for 10 days. The micromechanical properties of these tissues were evaluated by nano-indentation. The elastic modulus of human carious dentin improved after samples were immersed in colloidal β-Tricalcium Phosphate. The mineral density of carious dentin exposed to β-Tricalcium Phosphate increased more than that immersed in hydroxyapatite. However, since ...
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micromechanical property recovery of human carious dentin achieved with colloidal nano β Tricalcium Phosphate
Journal of Dental Research, 2008Co-Authors: Yo Shibata, Takashi Miyazaki, Yu Kataoka, M V SwainAbstract:Reconstitution of carious dentin has been recognized as difficult, because it progresses by loss of collagen polymerization and by demineralization under acidic conditions. Recently, colloidal alkaline nano-calcium Phosphate, prepared by electrical discharge in a buffered physiological saline solution, has been shown to be effective in the formulation of a bone-like biocomposite by simply being mixed with acidic collagen solution. It was hypothesized that colloidal calcium Phosphate was suitable for the reconstitution of carious dentin. Natural caries lesions in dentin from permanent teeth were exposed to colloidal hydroxyapatite and beta-Tricalcium Phosphate for 10 days. The micromechanical properties of these tissues were evaluated by nano-indentation. The elastic modulus of human carious dentin improved after samples were immersed in colloidal beta-Tricalcium Phosphate. The mineral density of carious dentin exposed to beta-Tricalcium Phosphate increased more than that immersed in hydroxyapatite. However, since it was not directly proportional to micromechanical recovery, mineral density alone was not a sufficient indicator of mechanical behavior.
Incheul Whang - One of the best experts on this subject based on the ideXlab platform.
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comparison of osteoconductivity and absorbability of beta Tricalcium Phosphate and hydroxyapatite in clinical scenario of opening wedge high tibial osteotomy
Journal of Materials Science: Materials in Medicine, 2016Co-Authors: Sagar Jaiswal, Incheul WhangAbstract:The purpose of this study was to compare the osteoconductivity, and absorbability of hydroxyapatite or beta-Tricalcium Phosphate in clinical scenario of opening wedge high tibial osteotomy Total 41 knees of 40 patients with follow up period of more than 1 year were enrolled. These patients were divided into two groups, Group I (22 knees, 21 patients) used hydroxyapatite and Group II (19 knees, 19 patients) used beta-Tricalcium Phosphate as a substitute in the opening gap. According to proven method, the osteoconductivity was assessed radiographically by the extent of new bone formation at osteotomy space and absorbability was evaluated by measuring the area occupied by substitute at immediate postoperative, postoperative 6 months and 1 year. Regarding preoperative demographic data, no significant differences were found between two groups. No statistically significant differences were found between two groups regarding lower limb alignment (mechanical femorotibial angle, weight-bearing line%) and posterior tibial slope at postoperative and final follow up radiographs. Concerning the osteoconductivity, there were no significant differences between two groups in any zone. However, the absorption rate was significantly greater in the Group II than in Group I at 6 months (Group I: 13.7 ± 6.8, group II: 35.3 ± 15.8, P = 0.001) and 1 year (Group I: 24.2 ± 6.3, Group II: 49.6 ± 14.3, P < 0.0001). The complications related to bone substitutes were not observed. Both hydroxyapatite and beta-Tricalcium Phosphate showed satisfactory gap healing without complications and can be successfully used as alternative healing materials in opening wedge high tibial osteotomy. Our study showed that beta-Tricalcium Phosphate has superior absorbability than hydroxyapatite. But osteoconductivity showed no significant difference.
Seung Min Ryu - One of the best experts on this subject based on the ideXlab platform.
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effect of water glass coating of Tricalcium Phosphate granules on in vivo bone formation
Journal of Biomaterials Applications, 2018Co-Authors: Seung Min Ryu, Myun Whan Ahn, Chul Hyun Park, Gun Woo Lee, In Hwan Song, Hyo Sae Ahn, Jooseong Kim, Sukyoung KimAbstract:BackgroundRecently, some authors introduced a water glass (WG, sodium-silicate glass; Na2O·SiO2·nH2O) coating over Tricalcium Phosphate (TCP) bioceramic to modulate its resorption rate and enhance ...
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effect of water glass coating of Tricalcium Phosphate on in vitro cellular proliferation and osteogenic differentiation
Journal of Biomaterials Applications, 2018Co-Authors: Seung Min Ryu, Myun Whan Ahn, In Hwan Song, Sukyoung Kim, Chan Hee Lee, Jae Hui Jeon, Hyo Sae AhnAbstract:Background In this study, the properties of the water glass (WG, sodium-silicate glass) were utilized to control the biodegradability of the beta Tricalcium Phosphate materials by the WG coating on the Tricalcium Phosphate disc surface with various coating thickness, chemistry, and heat-treatment. Methods Four types of disc specimens were prepared. A sample group A consisted of pure hydroxyapatite (HA) as a negative resorption control; a sample group B consisted of pure beta Tricalcium Phosphate as a positive resorption control; a sample group C consisted of beta Tricalcium Phosphate coated with WG as an early resorption model; and a sample group D consisted beta Tricalcium Phosphate coated with WG and heat-treated at 500°C as a delayed resorption model. Using human bone marrow-derived mesenchymal stem cells, for the analysis of cellular attachment and proliferative activity, 4-6-Diamidino-2-Phenylindole fluorescence technique was used. For the analysis of osteteogenic differentiation, alkaline phospastase (ALP) activity was measured. Results The mean z-scores of four groups (A, B, C, and D) in cellular attachment at 4 h after seeding were -1.21, -0.15, 0.42, and 0.94, respectively, and statistically significantly different in all groups respectively. Seven days after seeding, the mean z-scores of cellular proliferation were 1.97, 0.71, 1.48, and 1.83 in the four groups, respectively. The mean z-scores of the ALP activity per the mean z-scores of cell numbers of respective groups on the seventh day were 0.40, -1.51, 0.12, and 0.06, respectively, in four groups. Conclusion Initial cellular attachment is better on beta Tricalcium Phosphate than on HA and is enhanced by WG coating, especially with sintering at the high temperature. Cellular proliferation is considered to be increased by maintaining its attachment site through reduced dissolution of beta Tricalcium Phosphate by WG coating. Osteogenic differentiation in in-vitro study on the WG-coated beta Tricalcium Phosphate is thought to be as the result of increased silicon ion release from the WG.
Yo Shibata - One of the best experts on this subject based on the ideXlab platform.
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micromechanical property recovery of human carious dentin achieved with colloidal nano β Tricalcium Phosphate
Journal of Dental Research, 2008Co-Authors: Yo Shibata, Li Hong He, Takashi Miyazaki, Yu Kataoka, M V SwainAbstract:Reconstitution of carious dentin has been recognized as difficult, because it progresses by loss of collagen polymerization and by demineralization under acidic conditions. Recently, colloidal alkaline nano-calcium Phosphate, prepared by electrical discharge in a buffered physiological saline solution, has been shown to be effective in the formulation of a bone-like biocomposite by simply being mixed with acidic collagen solution. It was hypothesized that colloidal calcium Phosphate was suitable for the reconstitution of carious dentin. Natural caries lesions in dentin from permanent teeth were exposed to colloidal hydroxyapatite and β-Tricalcium Phosphate for 10 days. The micromechanical properties of these tissues were evaluated by nano-indentation. The elastic modulus of human carious dentin improved after samples were immersed in colloidal β-Tricalcium Phosphate. The mineral density of carious dentin exposed to β-Tricalcium Phosphate increased more than that immersed in hydroxyapatite. However, since ...
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micromechanical property recovery of human carious dentin achieved with colloidal nano β Tricalcium Phosphate
Journal of Dental Research, 2008Co-Authors: Yo Shibata, Takashi Miyazaki, Yu Kataoka, M V SwainAbstract:Reconstitution of carious dentin has been recognized as difficult, because it progresses by loss of collagen polymerization and by demineralization under acidic conditions. Recently, colloidal alkaline nano-calcium Phosphate, prepared by electrical discharge in a buffered physiological saline solution, has been shown to be effective in the formulation of a bone-like biocomposite by simply being mixed with acidic collagen solution. It was hypothesized that colloidal calcium Phosphate was suitable for the reconstitution of carious dentin. Natural caries lesions in dentin from permanent teeth were exposed to colloidal hydroxyapatite and beta-Tricalcium Phosphate for 10 days. The micromechanical properties of these tissues were evaluated by nano-indentation. The elastic modulus of human carious dentin improved after samples were immersed in colloidal beta-Tricalcium Phosphate. The mineral density of carious dentin exposed to beta-Tricalcium Phosphate increased more than that immersed in hydroxyapatite. However, since it was not directly proportional to micromechanical recovery, mineral density alone was not a sufficient indicator of mechanical behavior.
Sagar Jaiswal - One of the best experts on this subject based on the ideXlab platform.
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comparison of osteoconductivity and absorbability of beta Tricalcium Phosphate and hydroxyapatite in clinical scenario of opening wedge high tibial osteotomy
Journal of Materials Science: Materials in Medicine, 2016Co-Authors: Sagar Jaiswal, Incheul WhangAbstract:The purpose of this study was to compare the osteoconductivity, and absorbability of hydroxyapatite or beta-Tricalcium Phosphate in clinical scenario of opening wedge high tibial osteotomy Total 41 knees of 40 patients with follow up period of more than 1 year were enrolled. These patients were divided into two groups, Group I (22 knees, 21 patients) used hydroxyapatite and Group II (19 knees, 19 patients) used beta-Tricalcium Phosphate as a substitute in the opening gap. According to proven method, the osteoconductivity was assessed radiographically by the extent of new bone formation at osteotomy space and absorbability was evaluated by measuring the area occupied by substitute at immediate postoperative, postoperative 6 months and 1 year. Regarding preoperative demographic data, no significant differences were found between two groups. No statistically significant differences were found between two groups regarding lower limb alignment (mechanical femorotibial angle, weight-bearing line%) and posterior tibial slope at postoperative and final follow up radiographs. Concerning the osteoconductivity, there were no significant differences between two groups in any zone. However, the absorption rate was significantly greater in the Group II than in Group I at 6 months (Group I: 13.7 ± 6.8, group II: 35.3 ± 15.8, P = 0.001) and 1 year (Group I: 24.2 ± 6.3, Group II: 49.6 ± 14.3, P < 0.0001). The complications related to bone substitutes were not observed. Both hydroxyapatite and beta-Tricalcium Phosphate showed satisfactory gap healing without complications and can be successfully used as alternative healing materials in opening wedge high tibial osteotomy. Our study showed that beta-Tricalcium Phosphate has superior absorbability than hydroxyapatite. But osteoconductivity showed no significant difference.
