Upper Gastrointestinal Bleeding

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Wahid Wassef - One of the best experts on this subject based on the ideXlab platform.

  • Advances in management of nonvariceal Upper Gastrointestinal Bleeding.
    Current opinion in gastroenterology, 2018
    Co-Authors: Erik Aron Holzwanger, Mohamed Mahmoud, Wahid Wassef
    Abstract:

    Purpose of review To review new advances in managing nonvariceal Upper Gastrointestinal hemorrhage. Recent findings Implementation of various scoring systems in combination with video capsule endoscopy assists in stratifying and managing nonvariceal Upper Gastrointestinal Bleeding. New techniques such as thermocoagulation and hemoclips are useful to treat Bleeding. Summary The advancement of methods and procedures in managing nonvariceal Upper Gastrointestinal Bleeding has decreased mortality of patients presenting with this type of hemorrhage. In this chapter, we will be discussing various scores to stratify nonvariceal Upper Gastrointestinal Bleeding and techniques to stop Bleeding.

  • Nonvariceal Upper Gastrointestinal Bleeding.
    Current Opinion in Gastroenterology, 2014
    Co-Authors: Tina Park, Wahid Wassef
    Abstract:

    PURPOSE OF REVIEW: Acute Upper Gastrointestinal Bleeding is one of the most common medical emergencies. It is important to recognize potential etiologies of Upper Gastrointestinal Bleeding and understand therapeutic modalities available in achieving hemostasis. This article summarizes guidelines in management of acute nonvariceal Upper Gastrointestinal Bleeding and reviews recent advances in the field. RECENT FINDINGS: Recent study showed that patients who received blood transfusion with threshold hemoglobin below 7 g/dl rather than below 9 g/dl had significantly lower mortality at 45 days. Endoscopic therapy should be performed on actively Bleeding ulcers and ulcers with visible vessel or adherent clot. An over-the-scope clip is a novel device that can be used to achieve hemostasis. It may be a useful tool for achieving hemostasis for patients who failed endoscopic therapy with epinephrine injection, clip, or thermal therapy. Doppler ultrasound probe can evaluate arterial flow to the ulcer and identify ulcers that are at high risk of reBleeding. SUMMARY: Upper Gastrointestinal Bleeding from peptic ulcer disease is not a new clinical problem. Yet, the approach to management continues to evolve with the accumulation of data and well designed studies on the subject.

  • Upper Gastrointestinal Bleeding.
    Current opinion in gastroenterology, 2006
    Co-Authors: Noel B Martins, Wahid Wassef
    Abstract:

    This review provides an update on the management of Upper Gastrointestinal Bleeding with special attention to patient preparation, sedation, hemostatic techniques, and postprocedure care. In a large multicenter clinical trial, nurse-administered propofol sedation had a complication rate of less than 0.2%. The optimal management for an ulcer with adherent clot was confirmed by a meta-analysis to be clot removal and endoscopic treatment of the underlying lesion. A number of prospective studies have demonstrated that capsule endoscopy is the most sensitive imaging modality for identifying lesions in the small bowel and that double-balloon enteroscopy is the least invasive modality available for the management of these lesions. This update describes many recent advances in the diagnosis and management of Upper Gastrointestinal Bleeding. However, clearly, much work needs to be done in this field. Since propofol is not available for use in all endoscopy units, is there a better alternative for deep sedation? ReBleeding occurs in 20% of patients after endoscopic therapy, and so can we provide better outcomes with newer technologies (endoscopic suturing devices)? Finally, what is the best management for Helicobacter pylori-negative, nonsteroidal antiinflammatory drug-negative ulcer patients?

Ian M. Gralnek - One of the best experts on this subject based on the ideXlab platform.

Msph - One of the best experts on this subject based on the ideXlab platform.

David J. Bjorkman - One of the best experts on this subject based on the ideXlab platform.

Choichi Sugawa - One of the best experts on this subject based on the ideXlab platform.

  • Current therapy for nonvariceal Upper Gastrointestinal Bleeding
    Surgical Endoscopy And Other Interventional Techniques, 2004
    Co-Authors: J. M. Blocksom, S. Tokioka, Choichi Sugawa
    Abstract:

    Upper Gastrointestinal Bleeding continues to plague physicians despite the discovery of Helicobacter pylori and advances in medical therapy for peptic ulcer disease. Medical therapy with new nonsteroidal anti-inflammatory medications and somatostatin/octreotide and intravenous proton pump inhibitors provides hope for reducing the incidence of and treating Bleeding peptic ulcer disease. Endoscopic therapy remains the mainstay for diagnosis and treatment of Upper Gastrointestinal Bleeding. Many methods of endoscopic hemostasis have proven useful in Upper Gastrointestinal hemorrhage. Currently, combination therapy with epinephrine injection and bicap or heater probe therapy is most commonly employed in the United States. Angiography and embolization play a role primarily when endoscopic therapy is unsuccessful.

  • Control of Nonvariceal Upper Gastrointestinal Bleeding
    The SAGES Manual, 1
    Co-Authors: Choichi Sugawa
    Abstract:

    Early endoscopy has an important role in the evaluation and treatment of the patient with Upper Gastrointestinal Bleeding. Definition of the precise appearance of the lesions by endoscopy gives important information about the prognosis, risk of reBleeding, and indications for surgery. There are several effective endoscopic modalities for the control of Bleeding. This chapter describes several techniques currently used for endoscopic management of nonvariceal Upper Gastrointestinal Bleeding.