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Mary Allen Staat – One of the best experts on this subject based on the ideXlab platform.
Pediatric blood & cancer, 2018Co-Authors: Rachel Spring, Mary Allen Staat, Marilyn Rice, Hanna Schlaack, Charles T. QuinnAbstract:
There are conflicting guidelines about screening of internationally Adopted Children for glucose-6-phosphosphateydrogenase (G6PD) deficiency, a common genetic disorder. In a multi-ethnic population of 2,169 internationally Adopted Children, we found that the prevalence of G6PD deficiency was 1.6% overall and 2.2% in males. Prevalence differed by country or region of origin, ranging from 0 to 13% overall and 0 to 22% in males. The prevalence in females was 1%. A diagnosis of G6PD deficiency informs the treatment of malaria and enables education and counseling to prevent morbidity and mortality from G6PD deficiency. Screening for G6PD deficiency should be strongly considered for internationally Adopted Children.
intestinal parasite screening in internationally Adopted Children importance of multiple stool specimensPediatrics, 2011Co-Authors: Mary Allen Staat, Marilyn Rice, Stephanie Donauer, Sheena Mukkada, Michol Holloway, Amy Cassedy, Jennifer Kelley, Shelia SalisburyAbstract:
OBJECTIVE: Our goal was to determine the prevalence of intestinal parasites in internationally Adopted Children, to examine factors associated with infection, and to determine if evaluating multiple stool specimens increases the yield of parasite identification. METHODS: We evaluated internationally Adopted Children with at least 1 stool specimen submitted for ova and parasite testing within 120 days after arrival to the United States. In Children submitting 3 stool specimens, in which at least 1 specimen was positive for the pathogen studied, we examined whether multiple stool specimens increased the likelihood of pathogen identification. RESULTS: Of the 1042 Children studied, 27% had at least 1 pathogen identified; with pathogen-specific prevalence of Giardia intestinalis (19%), Blastocystis hominis (10%), Dientamoeba fragilis (5%), Entamoeba histolytica (1%), Ascaris lumbricoides (1%), and Hymenolepsis species (1%). The lowest prevalence occurred in South Korean (0%), Guatemalan (9%), and Chinese (13%) Children, and the highest prevalence occurred in Ethiopian (55%) and Ukrainian (74%) Children. Increasing age was significantly associated with parasite identification, whereas malnutrition and gastrointestinal symptoms were not. Overall, the yield of 1 stool specimen was 79% with pathogen recovery significantly increasing for 2 (92%) and 3 (100%) specimens, respectively (P CONCLUSIONS: We provide data for evidence-based guidelines for intestinal paraparasite screening in internationally Adopted Children. Gastrointestinal symptoms were not predictive of pathogen recovery, and multiple stool specimens increased pathogen identification in this high-risk group of Children.
serologic testing to verify the immune status of internationally Adopted Children against vaccine preventable diseasesVaccine, 2010Co-Authors: Mary Allen Staat, Laura Patricia Stadler, Marilyn Rice, Stephanie Donauer, Indi Trehan, Shelia SalisburyAbstract:
Definitive immunization guidelines for internationally Adopted Children are lacking. We examined whether these Children had serologic evidence of protection against vaccine-preventable diseases. For Children with ≥3 vaccine doses, overall protection was high for diphtheria (85%), tetanus (95%), polio (93%), hepatitis B (77%), and Hib (67%). For Children ≥12 months of age with ≥1 dose of measles, mumps, or rubella vaccines, 95%, 72%, and 94% were immune, respectively. Children without immunization documentation had lower immunity. Serologic testing was useful in verifying the immunization status in internationally Adopted Children with and without documentation of immunizations.
Megan R Gunnar – One of the best experts on this subject based on the ideXlab platform.
Development and Psychopathology, 2009Co-Authors: Jacqueline Bruce, Amanda R Tarullo, Megan R GunnarAbstract:
Postinstitutionalized Children frequently demonstrate persistent socioemotional difficulties. For example, some postinstitutionalized Children display an unusual lack of social reserve with unfamiliar adults. This behavior, which has been referred to as indiscriminate friendliness, disinhibited attachment behavior, and disinhibited social behavior, was examined by comparing Children internationally Adopted from institutional care to Children internationally Adopted from foster care and Children raised by their biological families. Etiological factors and behavioral correlates were also investigated. Both groups of Adopted Children displayed more disinhibited social behavior than the nonAdopted Children. Of the etiological factors examined, only the length of time in institutional care was related to disinhibited social behavior. Disinhibited social behavior was not significantly correlated with general cognitive ability, attachment-related behaviors, or basic emotion abilities. However, this behavior was negatively associated with inhibitory control abilities even after controlling for the length of time in institutional care. These results suggest that disinhibited social behavior might reflect underlying deficits in inhibitory control.
the international adoption project population based surveillance of minnesota parents who Adopted Children internationallyMaternal and Child Health Journal, 2008Co-Authors: Wendy L Hellerstedt, Richard M Lee, Megan R Gunnar, Harold D Grotevant, Nikki J Madsen, Dana E JohnsonAbstract:
Objectives To conduct the first population-based surveillance in the United States of parents who Adopted Children from countries outside of the United States.
Journal of Family Psychology, 2006Co-Authors: Richard M Lee, Harold D Grotevant, Wendy L Hellerstedt, Megan R GunnarAbstract:
Cultural socialization attitudes, beliefs, and parenting behaviors were examined in families with internationally Adopted Children. The authors hypothesized that parents with lower color-blind racial attitudes would be more likely to engage in enculturation and racialization parenting behaviors because they hold stronger beliefs in the value and importance of cultural socialization. Using data from the Minnesota International Adoption Project, the results support this mediation model of cultural socialization. Individual variations in cultural socialization also are discussed in terms of child development and shifting adoption attitudes and practices.
Femmie Juffer – One of the best experts on this subject based on the ideXlab platform.
Monographs of the Society for Research in Child Development, 2011Co-Authors: Femmie Juffer, Jesús Palacios, Lucy Le Mare, Edmund J. S. Sonuga‐barke, Wendy Tieman, Marian J. Bakermans-kranenburg, Panayiota Vorria, Marinus H. Van Ijzendoorn, Frank C VerhulstAbstract:
This chapter first presents a review of research on the development of Adopted Children, focusing on meta-analytic evidence and highlighting comparisons between Adopted Children with and without histories of early adversity. Some methodological issues arising from this literature are considered as well. Second, 7 longitudinal studies of Adopted Children‘s development are described, and the convergence of findings across the longitudinal studies and with the cross-sectionally based meta-analytic evidence is discussed. Third, the role of the adoptive family in supporting Adopted Children‘s development is explored.
Children and Youth Services Review, 2009Co-Authors: Linda Van Den Dries, Femmie Juffer, Marinus H Van Ijzendoorn, Marian J BakermanskranenburgAbstract:
Adopted Children are hypothesized to be at risk of insecure attachment relationships because of their background of institutional care, maltreatment and neglect. We conducted two series of meta-analyses, one using only observational assessments of attachment and one using both observational and self-report assessments. Observational assessments showed that Children who were Adopted before 12Â months of age were as securely attached as their non-Adopted peers, whereas Children Adopted after their first birthday showed less attachment security than non-Adopted Children (dÂ =Â 0.80, CIÂ =Â 0.49-1.12). Regarding the overall effect for attachment security, adoptees were comparable to foster Children. Adopted Children showed more disorganized attachments compared to their non-Adopted peers (trimmed dÂ =Â 0.36, CIÂ =Â 0.04-0.68), but again were comparable to foster Children (trimmed dÂ =Â 0.35, CIÂ =Â 0.02-0.67). Compared to institutionalized Children, adoptees were less often disorganized attached. When self-report measures of attachment were included no difference was found between adoptees and their non-Adopted counterparts (trimmed dÂ =Â 0.12, CIÂ =Â -Â 0.02-0.26, 39 studies, NÂ =Â 2912 Adopted Children). Compared to institutionalized Children, (early) adoption proves to be an effective intervention in the domain of attachment.
adoption is a successful natural intervention enhancing Adopted Children s iq and school performanceCurrent Directions in Psychological Science, 2005Co-Authors: Marinus H. Van Ijzendoorn, Femmie JufferAbstract:
Is the cognitive development of Adopted Children different from that of (a) Children who have remained in institutional care or in their birth families or (b) their current (environmental) nonAdopted siblings or peers? We attempt to answer these questions on the basis of a meta-analysis of 62 studies including 17,767 Adopted Children. Compared to their nonAdopted siblings or peers who stayed behind, Adopted Children scored substantially higher on IQ tests and they performed much better at school. Compared to their current nonAdopted environmental peers or siblings, Adopted Children showed similar IQ scores but their school performance and language abilities lagged somewhat behind. Most importantly, we found a twofold increase in special-education referrals in Adopted Children compared to their nonAdopted peers. Taken together, the findings document the positive impact of adoption on Children‘s cognitive development and Adopted Children‘s remarkably normal cognitive competence but somewhat delayed school p…
Helena Lapinleimu – One of the best experts on this subject based on the ideXlab platform.
Intestinal parasites may be associated with later behavioral problems in internationally Adopted Children.PloS one, 2021Co-Authors: Anna-riitta Heikkilä, Marko Elovainio, Hanna Raaska, Jaakko Matomäki, Jari Sinkkonen, Helena LapinleimuAbstract:
AIM At arrival in new home country, internationally Adopted Children often have intestinal parasites. International adoptees also exhibit more behavioral problems than their biological peers. We examined whether intestinal paraparasite infections in international adoptees on arrival in Finland are associated with their later behavioral and emotional problems. METHODS Data for this study were sourced from the Finnish Adoption Study (FinAdo) based on parental questionnaires for all internationally Adopted Children under 18 years (n = 1450) who arrived in Finland from 1985 to 2007. A total of 1293 families provided sufficient information on the adoptee’s background, parasitic status on arrival, and behavioral symptoms at the median time of 5 years after arrival (mean age = 7.8 years). Behavioral and emotional disorders were evaluated with the Child Behavior Checklist (CBCL). Statistical analyses were conducted using linear regression. RESULTS Of the 1293 families, parents of 206 adoptive Children reported intestinal parasites in their Adopted Children on arrival. Parasite-infected Children had subsequently higher CBCL problem scores than the Children without parasites (p < 0.001). The association between intestinal parasites and later behavioral problems was stronger than that between intestinal parasites and any other factors measured in this study, except disability. LIMITATIONS The control group was naturally provided by the Adopted Children without parasite infections, but we could not compare the Adopted Children to non-Adopted Children without a defined parasite infection. We were unable to specify the effects associated with a specific parasite type. It was not possible either to include multiple environmental factors that could have been associated with behavioral problems in the models, which indicated only modest explanatory values. CONCLUSIONS In this study, intestinal paraparasite infections in early childhood may be associated with Children‘s later psychological wellbeing, even in Children who move to a country with a low prevalence of parasites. Our findings may support further developments pertaining to the gut-brain theory.
internationally Adopted Children in finland parental evaluations of symptoms of reactive attachment disorder and learning difficulties finado studyChild Care Health and Development, 2012Co-Authors: Marko Elovainio, Hanna Raaska, Jaakko Matomäki, Jari Sinkkonen, Sanna Makipaa, Helena LapinleimuAbstract:
Objective This study investigated the association between psychological symptoms, such as features of reactive attachment disorder (RAD), and learning difficulties among international adoptees in Finland. Methods The data for this study came from the FINnish ADOption (FINADO) study covering all internationally Adopted Children in Finland (n= 1450), with a response rate of 55.7%. The subsample consisted of 395 Adopted Children aged 9–15 (51.6% girls, 48.4% boys). Learning difficulties were evaluated by a screening questionnaire ‘Five To Fifteen’ and symptoms of RAD by FINADO RAD scale. Results The parents estimated that one-third (33.4%) of the internationally Adopted Children had some, and 12.7% had severe learning difficulties, i.e. three and six times more than in normal population, respectively. RAD symptoms at the time of adoption were associated with learning difficulties at school age (OR 4.57, 95% CI 2.57–8.13). Conclusions Learning difficulties are common among internationally Adopted Children in Finland and symptoms of RAD are associated with a child’s learning difficulties.
Natasha Kelly – One of the best experts on this subject based on the ideXlab platform.
Helicobacter, 2003Co-Authors: Laurie C. Miller, Natasha Kelly, Martijn Tannemaat, Richard J. GrandAbstract:
Background.Helicobacter pylori (H. pylori) infection has been linked to gastritis, diarrhea, peptic ulcers, failure-to-thrive, anemia, as well as predisposition to gastric malignancies. Because many internationally Adopted Children have diarrhea, failure-to-thrive, and anemia on arrival to the US, we determined the prevalence of HP antibodies among these Children. Methods. Serum samples from 226 unselected Children from 18 countries who were evaluated in the International Adoption Clinic at New England Medical Center were tested for antibodies to H. pylori. The results of serologic screening were analyzed in relation to age at adoption, site of residence prior to adoption, weight and height, and the presence or absence of anemia, diarrhea, or intestinal parasites. Results. 31% of internationally Adopted Children had antibodies to H. pylori. The presence of H. pylori-antibodies was associated with residence in an orphanage (vs. foster care) prior to adoption, older age at adoption, and coinfection with intestinal parasites. No direct effects on height or weight were identified; no associations with diarrhea or anemia were found. Conclusions. Internationally Adopted Children have a high incidence of exposure to H. pylori, as diagnosed serologically. Residence in an orphanage (compared with foster care), older age at adoption, and coinfection with intestinal parasites were more common among Children seropositive for anti-H. pylori antibodies.
Pediatrics, 2001Co-Authors: Laurie C. Miller, Kathleen Comfort, Natasha KellyAbstract:
To the Editor. Many internationally Adopted Children arrive in the United States with incomplete or uncertain vaccination status. Some have suggested that even Children who have received adequate numbers of vaccines for tetanus and polio have inadequate titers, resulting from poor immunogenicity of the vaccines, impaired immune responses (possibly attributable to malnutrition), or incorrect records.1,,2 Some physicians recommend revaccinating all international adoptees at arrival in the United States.3We …