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Judith Sackoff – One of the best experts on this subject based on the ideXlab platform.

  • concurrent hiv AIDS Diagnosis increases the risk of short term hiv related death among persons newly diagnosed with AIDS 2002 2005
    Aids Patient Care and Stds, 2008
    Co-Authors: David B. Hanna, Melissa R. Pfeiffer, Lucia V. Torian, Judith Sackoff

    Abstract:

    Despite the overall effectiveness and availability of highly active antiretroviral therapy (HAART), 1500 HIV-related deaths still occur annually in New York City. In considering ways to further reduce deaths, we assessed the contribution of concurrent HIV/AIDS Diagnosis to HIV-related mortality in New York City among persons newly diagnosed with AIDS. We used Cox regression to conduct a retrospective cohort analysis of HIV-related mortality among 15,211 residents age 13+ reported with AIDS to the population-based HIV/AIDS registry between January 2002 and June 2005. Concurrent HIV/AIDS Diagnosis was defined as a Diagnosis of AIDS occurring within 1 month of initial Diagnosis of HIV. HIV-related mortality was 20.2% among persons diagnosed concurrently and 12.2% among those diagnosed nonconcurrently (p < 0.0001). Concurrent HIV/AIDS was associated with more than twice the risk of HIV-related death within the 4 months after Diagnosis (hazard ratio [HR] 2.27, 95% confidence interval [CI] 1.94–2.65) but no inc…

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  • Concurrent HIV/AIDS Diagnosis increases the risk of short-term HIV-related death among persons newly diagnosed with AIDS, 2002-2005.
    AIDS patient care and STDs, 2008
    Co-Authors: David B. Hanna, Melissa R. Pfeiffer, Lucia V. Torian, Judith Sackoff

    Abstract:

    Despite the overall effectiveness and availability of highly active antiretroviral therapy (HAART), 1500 HIV-related deaths still occur annually in New York City. In considering ways to further reduce deaths, we assessed the contribution of concurrent HIV/AIDS Diagnosis to HIV-related mortality in New York City among persons newly diagnosed with AIDS. We used Cox regression to conduct a retrospective cohort analysis of HIV-related mortality among 15,211 residents age 13+ reported with AIDS to the population-based HIV/AIDS registry between January 2002 and June 2005. Concurrent HIV/AIDS Diagnosis was defined as a Diagnosis of AIDS occurring within 1 month of initial Diagnosis of HIV. HIV-related mortality was 20.2% among persons diagnosed concurrently and 12.2% among those diagnosed nonconcurrently (p < 0.0001). Concurrent HIV/AIDS was associated with more than twice the risk of HIV-related death within the 4 months after Diagnosis (hazard ratio [HR] 2.27, 95% confidence interval [CI] 1.94–2.65) but no inc…

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Jens D. Lundgren – One of the best experts on this subject based on the ideXlab platform.

  • HIV-related non-Hodgkin’s lymphoma among European AIDS patients. AIDS in Europe Study Group. AIDS in Europe Study Group
    European journal of haematology, 2009
    Co-Authors: Court Pedersen, Christine Katlama, Antonio Chiesi, Anne M Johnson, S. E. Barton, Peter Skinhøj, J. Van Lunzen, Bernard Hirschel, S. Maayan, Jens D. Lundgren

    Abstract:

    The epidemiology of HIV associated non-Hodgkin’s lymphoma (NHL) was investigated in 6550 European patients with AIDS. NHL was diagnosed in 3.5% of all patients at the time of the AIDS Diagnosis. Although the probability of being diagnosed with NHL at AIDS Diagnosis was significantly higher among intravenous drug users than among homosexual men, and was associated with increasing age, the observed incidences of NHL were more strikingly similar than any differences. The rate of developing NHL after a previous AIDS Diagnosis was 2.4 per 100 patient years of follow-up, and remained constant during a 5-year follow-up period. While primary brain lymphomas comprised only 9% of NHL diagnosed at the time of AIDS, they comprised 38% of NHL diagnosed after AIDS (p < 0.001). The prognosis for patients with NHL at AIDS Diagnosis was poor with a median survival of 5 months. A Diagnosis of primary brain lymphoma was uniformly associated with a poor outcome. It is concluded that the probability of developing NHL in late stage HIV infection is lower than previously anticipated from the results of small studies on patients receiving long-term anti-retroviral therapy.

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  • Influence of Age on Rates of New AIDS-defining Diseases and Survival in 6546 AIDS Patients
    Scandinavian journal of infectious diseases, 1997
    Co-Authors: Ulla Balslev, Court Pedersen, Andrew N. Phillips, Antonella D'arminio Monforte, George S. Stergiou, F Antunes, Fiona Mulcahy, Per Olav Pehrson, Jens D. Lundgren

    Abstract:

    It has consistently been reported that older AIDS patients have a shortened survival compared with younger patients. The aim of the present study was to investigate whether this difference in survival is caused by differences in the pattern of the complicating diseases. Information on patient follow-up after the AIDS Diagnosis was obtained by retrospective case note review. The 6,546 patients were followed from the time of AIDS Diagnosis as part of the multicentre AIDS in Europe study, which examined AIDS cases diagnosed at 52 centres in 17 European countries between 1979 and 1989. Occurrence of AIDS-defining events and demographic variables were recorded for all patients, and CD4 lymphocyte count at the time of AIDS Diagnosis for approximately half the patients. After adjusting for imbalances in other variables, persons ≥50 years of age had a significantly higher risk of contracting AIDS wasting syndrome, AIDS dementia complex and oesophageal candidiasis after the initial AIDS Diagnosis, compared with ag…

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  • Epidemiology of cryptosporidiosis among European AIDS patients.
    Sexually Transmitted Infections, 1996
    Co-Authors: Court Pedersen, Sven A. Danner, Adriano Lazzarin, Michel P. Glauser, Rainer Weber, Christine Katlama, S. Barton, Jens D. Lundgren

    Abstract:

    OBJECTIVE: To study epidemiology and possible risk factors associated with the development of cryptosporidiosis among European patients with AIDS. METHODS: An inception cohort of 6548 patients with AIDS, consecutively diagnosed from 1979 to 1989, from 52 centres in 17 European countries was studied. Data on all AIDS defining events were collected retrospectively from patients9 clinical records. Kaplan-Meier estimates, log rank tests and Cox proportional hazard models were used to examine for possible risk factors associated with cryptosporidiosis. RESULTS: Cryptosporidiosis was diagnosed in 432 (6.6%) patients, 216 at time of the AIDS Diagnosis and 216 during follow-up. The probability of being diagnosed with cryptosporidiosis at AIDS Diagnosis was significantly lower for intravenous drug users (1.3%) than for homosexual men (4.1%) and for patients belonging to other transmission categories (4.0%) (p

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David B. Hanna – One of the best experts on this subject based on the ideXlab platform.

  • concurrent hiv AIDS Diagnosis increases the risk of short term hiv related death among persons newly diagnosed with AIDS 2002 2005
    Aids Patient Care and Stds, 2008
    Co-Authors: David B. Hanna, Melissa R. Pfeiffer, Lucia V. Torian, Judith Sackoff

    Abstract:

    Despite the overall effectiveness and availability of highly active antiretroviral therapy (HAART), 1500 HIV-related deaths still occur annually in New York City. In considering ways to further reduce deaths, we assessed the contribution of concurrent HIV/AIDS Diagnosis to HIV-related mortality in New York City among persons newly diagnosed with AIDS. We used Cox regression to conduct a retrospective cohort analysis of HIV-related mortality among 15,211 residents age 13+ reported with AIDS to the population-based HIV/AIDS registry between January 2002 and June 2005. Concurrent HIV/AIDS Diagnosis was defined as a Diagnosis of AIDS occurring within 1 month of initial Diagnosis of HIV. HIV-related mortality was 20.2% among persons diagnosed concurrently and 12.2% among those diagnosed nonconcurrently (p < 0.0001). Concurrent HIV/AIDS was associated with more than twice the risk of HIV-related death within the 4 months after Diagnosis (hazard ratio [HR] 2.27, 95% confidence interval [CI] 1.94–2.65) but no inc…

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  • Concurrent HIV/AIDS Diagnosis increases the risk of short-term HIV-related death among persons newly diagnosed with AIDS, 2002-2005.
    AIDS patient care and STDs, 2008
    Co-Authors: David B. Hanna, Melissa R. Pfeiffer, Lucia V. Torian, Judith Sackoff

    Abstract:

    Despite the overall effectiveness and availability of highly active antiretroviral therapy (HAART), 1500 HIV-related deaths still occur annually in New York City. In considering ways to further reduce deaths, we assessed the contribution of concurrent HIV/AIDS Diagnosis to HIV-related mortality in New York City among persons newly diagnosed with AIDS. We used Cox regression to conduct a retrospective cohort analysis of HIV-related mortality among 15,211 residents age 13+ reported with AIDS to the population-based HIV/AIDS registry between January 2002 and June 2005. Concurrent HIV/AIDS Diagnosis was defined as a Diagnosis of AIDS occurring within 1 month of initial Diagnosis of HIV. HIV-related mortality was 20.2% among persons diagnosed concurrently and 12.2% among those diagnosed nonconcurrently (p < 0.0001). Concurrent HIV/AIDS was associated with more than twice the risk of HIV-related death within the 4 months after Diagnosis (hazard ratio [HR] 2.27, 95% confidence interval [CI] 1.94–2.65) but no inc…

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