The Experts below are selected from a list of 5277 Experts worldwide ranked by ideXlab platform
Chengjian Zheng - One of the best experts on this subject based on the ideXlab platform.
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Chemical Fingerprint and quantitative analysis for the quality evaluation of vitex negundo seeds by reversed phase high performance liquid chromatography coupled with hierarchical clustering analysis
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Xiuqing Li, Khalid Rahman, Chengjian ZhengAbstract:A simple and efficient method was developed for the Chemical Fingerprint analysis and simultaneous determination of four phenylnaphthalene-type lignans in Vitex negundo seeds using high-performance liquid chromatography with diode array detection. For Fingerprint analysis, 13 V. negundo seed samples were collected from different regions in China, and the Fingerprint chromatograms were matched by the computer-aided Similarity Evaluation System for Chromatographic Fingerprint of TCM (Version 2004A). A total of 21 common peaks found in all the chromatograms were used for evaluating the similarity between these samples. Additionally, simultaneous quantification of four major bioactive ingredients was conducted to assess the quality of V. negundo seeds. Our results indicated that the contents of four lignans in V. negundo seeds varied remarkably in herbal samples collected from different regions. Moreover, the hierarchical clustering analysis grouped these 13 samples into three categories, which was consistent with the chemotypes of those chromatograms. The method developed in this study provides a substantial foundation for the establishment of reasonable quality control standards for V. negundo seeds.
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Chemical Fingerprint and quantitative analysis for the quality evaluation of vitex negundo seeds by reversed phase high performance liquid chromatography coupled with hierarchical clustering analysis
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Xiuqing Li, Khalid Rahman, Chengjian ZhengAbstract:A simple and efficient method was developed for the Chemical Fingerprint analysis and simultaneous determination of four phenylnaphthalene-type lignans in Vitex negundo seeds using high-performance liquid chromatography with diode array detection. For Fingerprint analysis, 13 V. negundo seed samples were collected from different regions in China, and the Fingerprint chromatograms were matched by the computer-aided Similarity Evaluation System for Chromatographic Fingerprint of TCM (Version 2004A). A total of 21 common peaks found in all the chromatograms were used for evaluating the similarity between these samples. Additionally, simultaneous quantification of four major bioactive ingredients was conducted to assess the quality of V. negundo seeds. Our results indicated that the contents of four lignans in V. negundo seeds varied remarkably in herbal samples collected from different regions. Moreover, the hierarchical clustering analysis grouped these 13 samples into three categories, which was consistent with the chemotypes of those chromatograms. The method developed in this study provides a substantial foundation for the establishment of reasonable quality control standards for V. negundo seeds. This article is protected by copyright. All rights reserved.
Xiuqing Li - One of the best experts on this subject based on the ideXlab platform.
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Chemical Fingerprint and quantitative analysis for the quality evaluation of vitex negundo seeds by reversed phase high performance liquid chromatography coupled with hierarchical clustering analysis
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Xiuqing Li, Khalid Rahman, Chengjian ZhengAbstract:A simple and efficient method was developed for the Chemical Fingerprint analysis and simultaneous determination of four phenylnaphthalene-type lignans in Vitex negundo seeds using high-performance liquid chromatography with diode array detection. For Fingerprint analysis, 13 V. negundo seed samples were collected from different regions in China, and the Fingerprint chromatograms were matched by the computer-aided Similarity Evaluation System for Chromatographic Fingerprint of TCM (Version 2004A). A total of 21 common peaks found in all the chromatograms were used for evaluating the similarity between these samples. Additionally, simultaneous quantification of four major bioactive ingredients was conducted to assess the quality of V. negundo seeds. Our results indicated that the contents of four lignans in V. negundo seeds varied remarkably in herbal samples collected from different regions. Moreover, the hierarchical clustering analysis grouped these 13 samples into three categories, which was consistent with the chemotypes of those chromatograms. The method developed in this study provides a substantial foundation for the establishment of reasonable quality control standards for V. negundo seeds.
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Chemical Fingerprint and quantitative analysis for the quality evaluation of vitex negundo seeds by reversed phase high performance liquid chromatography coupled with hierarchical clustering analysis
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Xiuqing Li, Khalid Rahman, Chengjian ZhengAbstract:A simple and efficient method was developed for the Chemical Fingerprint analysis and simultaneous determination of four phenylnaphthalene-type lignans in Vitex negundo seeds using high-performance liquid chromatography with diode array detection. For Fingerprint analysis, 13 V. negundo seed samples were collected from different regions in China, and the Fingerprint chromatograms were matched by the computer-aided Similarity Evaluation System for Chromatographic Fingerprint of TCM (Version 2004A). A total of 21 common peaks found in all the chromatograms were used for evaluating the similarity between these samples. Additionally, simultaneous quantification of four major bioactive ingredients was conducted to assess the quality of V. negundo seeds. Our results indicated that the contents of four lignans in V. negundo seeds varied remarkably in herbal samples collected from different regions. Moreover, the hierarchical clustering analysis grouped these 13 samples into three categories, which was consistent with the chemotypes of those chromatograms. The method developed in this study provides a substantial foundation for the establishment of reasonable quality control standards for V. negundo seeds. This article is protected by copyright. All rights reserved.
Haiyu Xu - One of the best experts on this subject based on the ideXlab platform.
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study of Chemical Fingerprint for yuanhu zhitong tablet by uplc q tof ms
Journal of Liquid Chromatography & Related Technologies, 2012Co-Authors: Haiyu Xu, Yingchun Zhang, Bin Huang, Dan Shen, Geng Li, Hongjun YangAbstract:An ultra-performance liquid chromatography coupled with quadrupole time of flight tandem mass spectrometry (UPLC/Q-TOF-MS) was first employed to establish the chromatographic Fingerprint and thereby identify the major components of Yuanhu Zhitong tablet (YZT), a traditional Chinese medicine. Fingerprint was established by analyzing 15 different batches of YZT, in which we obtained 17 common peaks with 18 constituents. Fifteen components were identified in the Fingerprint with reference to the standards and literature data, including protopine, α-allocryptopine, coptisine, tetrahydropalmatine, tetrahydroberberine, corydaline, palmatine, berberine, byakangelicol, dehydrocorydaline, oxypeucedanin, imperatorin, phelloptorin, isoimperatorin, and osthole. Each of these was separated by using a Waters Acquity UPLC BEH C18 (2.1 × 50 mm, 1.7 µm) column with linear gradient elution of 0.2% formic acid water-acetonitrile. Meanwhile, the hierarchical cluster analysis was applied to evaluate the variation of the YZTs ...
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Chemical Fingerprint analysis of phellodendri amurensis cortex by ultra performance lc q tof ms methods combined with chemometrics
IEEE Journal of Solid-state Circuits, 2010Co-Authors: Yubo Li, Tiejun Zhang, Xiaolan Zhang, Haiyu XuAbstract:Ultra performance LC with quadrupole TOF MS (UPLC/Q-TOF-MS) Fingerprinting is first developed for the identification of the major components of Phellodendri Amurensis Cortex (PAC). The PAC samples are separated using a Waters ACQUITY UPLC BEH C18 (2.150 mm, 1.7 mm) by linear gradient elution using water (containing 0.2% formic acid) and acetonitrile (containing 0.2% formic acid) as the mobile phase. Ten batches of PAC are selected to construct the UPLC/Q-TOF-MS Fingerprint. Sixteen common peaks in the Fingerprint are obtained, ten of which are tentatively identified, with reference to the literature data, as phellodendrine, magnoflorine, tetrahydropjatrorrhizine, menisperine, tetrahydropalmatine, jatrorrhizine, palmatine, berberine, obacunone, and limonin. Chemometric methods are also employed to evaluate the variation of herbal drugs and other closely related herbs based on the characteristics of peaks in the UPLC/Q-TOF-MS profiles. The developed Fingerprint assay is a powerful method that may be used to conduct quality control of PAC.
Georg Steinhauser - One of the best experts on this subject based on the ideXlab platform.
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identification of a Chemical Fingerprint linking the undeclared 2017 release of 106ru to advanced nuclear fuel reprocessing
Proceedings of the National Academy of Sciences of the United States of America, 2020Co-Authors: Michael W Cooke, Georg Steinhauser, Adrian Botti, Kurt UngarAbstract:The undeclared release and subsequent detection of ruthenium-106 (106Ru) across Europe from late September to early October of 2017 prompted an international effort to ascertain the circumstances of the event. While dispersion modeling, corroborated by ground deposition measurements, has narrowed possible locations of origin, there has been a lack of direct empirical evidence to address the nature of the release. This is due to the absence of radiological and Chemical signatures in the sample matrices, considering that such signatures encode the history and circumstances of the radioactive contaminant. In limiting cases such as this, we herein introduce the use of selected Chemical transformations to elucidate the Chemical nature of a radioactive contaminant as part of a nuclear forensic investigation. Using established ruthenium polypyridyl chemistry, we have shown that a small percentage (1.2 ± 0.4%) of the radioactive 106Ru contaminant exists in a polychlorinated Ru(III) form, partly or entirely as β-106RuCl3, while 20% is both insoluble and Chemically inert, consistent with the occurrence of RuO2, the thermodynamic endpoint of the volatile RuO4. Together, these findings present a clear signature for nuclear fuel reprocessing activity, specifically the reductive trapping of the volatile and highly reactive RuO4, as the origin of the release. Considering that the previously established 103Ru:106Ru ratio indicates that the spent fuel was unusually young with respect to typical reprocessing protocol, it is likely that this exothermic trapping process proved to be a tipping point for an already turbulent mixture, leading to an abrupt and uncontrolled release.
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Chemical and radioanalytical investigations of 106Ru-containing air filters from Vienna in fall 2017: searching for stable element anomalies
Journal of Radioanalytical and Nuclear Chemistry, 2018Co-Authors: Dorian Zok, Johannes H. Sterba, Georg SteinhauserAbstract:Related to the recent nuclear release of radioactive ruthenium isotopes in fall 2017, we analyzed air filters from Vienna for irregularities in the (stable) elemental composition of particulate matter from this period. Methods were SEM/EDXS and INAA. For comparison, a reference filter from 2007 and blank filters were used. The Chemical Fingerprint encompassed 28 elements. The results show no indication for a considerable change in the elemental composition of the suspended matter. For example, no anomalies in the abundance of platinum group elements were found. The results suggest that the release of 106Ru had not been accompanied by a release of detectable amounts of (activatable) stable elements.
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Chemical and radioanalytical investigations of ^106Ru-containing air filters from Vienna in fall 2017: searching for stable element anomalies
Journal of Radioanalytical and Nuclear Chemistry, 2018Co-Authors: Johannes H. Sterba, Georg SteinhauserAbstract:Related to the recent nuclear release of radioactive ruthenium isotopes in fall 2017, we analyzed air filters from Vienna for irregularities in the (stable) elemental composition of particulate matter from this period. Methods were SEM/EDXS and INAA. For comparison, a reference filter from 2007 and blank filters were used. The Chemical Fingerprint encompassed 28 elements. The results show no indication for a considerable change in the elemental composition of the suspended matter. For example, no anomalies in the abundance of platinum group elements were found. The results suggest that the release of ^106Ru had not been accompanied by a release of detectable amounts of (activatable) stable elements.
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adsorption of ions onto high silica volcanic glass
Applied Radiation and Isotopes, 2008Co-Authors: Georg Steinhauser, Max BichlerAbstract:Abstract Chemical Fingerprint techniques are frequently applied to airborne volcanic eruption products, so-called tephra, such as ash and pumice for archeological and geoscientific purposes. However, in some cases, a meaningful interpretation of the results is complicated by superficial contaminations. Therefore, this situation was simulated by the use of powdered rhyolitic pumice to investigate its capability to adsorb several ions from aqueous solutions. Using neutron activation analysis, adsorption could be proven for Cr 3+ , Cr 2 O 7 2− (dichromate), Fe 3+ , Co 2+ , HAsO 4 2− (hydrogen arsenate), Rb + , Sr 2+ , Cs + , Ba 2+ , La 3+ , Ce 3+ , Ce 4+ , Sm 3+ , Th 4+ and UO 2 2+ , which is a clear evidence for the interaction of those ions with the volcanic glass. In our experiments, pumice powder showed the ability to adsorb ions in the range from 1.8 mg kg −1 (in case of HAsO 4 2− ) to 5.8 wt% (in case of Fe 3+ ). Adsorption is probably due to ion-exchange reactions. It could also be shown that a few ions are not adsorbed in detectable quantities: Na + , K + , Fe 2+ , Zn 2+ and Nd 3+ . The knowledge about adsorption of ions enables us not only to examine the possible influence of contaminations where Chemical Fingerprinting methods are applied to volcanic material for archaeometry, but it also suggests the technical application of pumiceous materials for technical purposes, like water purification or as an adsorbent in the final storage of nuclear waste. In another series of INAA supported experiments, the influence of Chemicals like ascorbic acid, acetic acid, HCl, HF, HNO 3 , H 2 O, H 2 O 2 , H 3 PO 4 , H 2 SO 4 , NaOH and NH 3 on the bulk composition of pumice powder was investigated—resulting in no detectable change. We conclude that superficially contaminated tephra can be washed in diluted HF to remove contaminations without influencing the Chemical Fingerprint.
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Chemical Fingerprints" of pumice from Cappadocia (Turkey) and Kos (Greece) for archaeological applications.
Applied Radiation and Isotopes, 2006Co-Authors: Georg Steinhauser, Johannes H. Sterba, Max BichlerAbstract:Abstract Pumice has been used as a serviceable abrasive or religious artefact since antiquity and has therefore been an object of trade. It can be found in excavations of ancient workshops all over the Mediterranean. Pumice lumps from the major pumice-bearing rhyolitic tephra units in Cappadocia—the Central Anatolian Volcanic Province, Turkey (in particular the ignimbrites Kavak, Cemilkoy, Tahar, Gordeles, and the volcanic complexes of Acigol and Hasan Dagi), were sampled and analyzed for major and trace element concentrations using instrumental neutron activation analysis (INAA). Elements determined were Na, K, Sc, Cr, Fe, Co, Zn, As, Rb, Zr, Sb, Cs, Ba, La, Ce, Nd, Sm, Eu, Tb, Yb, Lu, Hf, Ta, Th, and U. Since the distribution of those elements is characteristic of the products of a certain eruption, this “Chemical Fingerprint” can be used to establish the origin of an unknown pumice sample by comparison with samples of known origin. In the course of this study, it could be shown that one pumice finding from the excavation in Miletos (Turkey) probably originates from the Hasan Dagi volcanic complex in Cappadocia. Since it is known that the population in Miletos focused their trade connections on the Mediterranean, this result is somewhat surprising. Two other samples from Miletos show a very high similarity to the Chemical Fingerprint of pumice from the Kos Plateau Tuff (KPT; Greece): In one case, the identification is doubtless, in the other case identification as KPT seems quite probable.
Khalid Rahman - One of the best experts on this subject based on the ideXlab platform.
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Chemical Fingerprint and quantitative analysis for the quality evaluation of vitex negundo seeds by reversed phase high performance liquid chromatography coupled with hierarchical clustering analysis
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Xiuqing Li, Khalid Rahman, Chengjian ZhengAbstract:A simple and efficient method was developed for the Chemical Fingerprint analysis and simultaneous determination of four phenylnaphthalene-type lignans in Vitex negundo seeds using high-performance liquid chromatography with diode array detection. For Fingerprint analysis, 13 V. negundo seed samples were collected from different regions in China, and the Fingerprint chromatograms were matched by the computer-aided Similarity Evaluation System for Chromatographic Fingerprint of TCM (Version 2004A). A total of 21 common peaks found in all the chromatograms were used for evaluating the similarity between these samples. Additionally, simultaneous quantification of four major bioactive ingredients was conducted to assess the quality of V. negundo seeds. Our results indicated that the contents of four lignans in V. negundo seeds varied remarkably in herbal samples collected from different regions. Moreover, the hierarchical clustering analysis grouped these 13 samples into three categories, which was consistent with the chemotypes of those chromatograms. The method developed in this study provides a substantial foundation for the establishment of reasonable quality control standards for V. negundo seeds.
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Chemical Fingerprint and quantitative analysis for the quality evaluation of vitex negundo seeds by reversed phase high performance liquid chromatography coupled with hierarchical clustering analysis
IEEE Journal of Solid-state Circuits, 2016Co-Authors: Xiuqing Li, Khalid Rahman, Chengjian ZhengAbstract:A simple and efficient method was developed for the Chemical Fingerprint analysis and simultaneous determination of four phenylnaphthalene-type lignans in Vitex negundo seeds using high-performance liquid chromatography with diode array detection. For Fingerprint analysis, 13 V. negundo seed samples were collected from different regions in China, and the Fingerprint chromatograms were matched by the computer-aided Similarity Evaluation System for Chromatographic Fingerprint of TCM (Version 2004A). A total of 21 common peaks found in all the chromatograms were used for evaluating the similarity between these samples. Additionally, simultaneous quantification of four major bioactive ingredients was conducted to assess the quality of V. negundo seeds. Our results indicated that the contents of four lignans in V. negundo seeds varied remarkably in herbal samples collected from different regions. Moreover, the hierarchical clustering analysis grouped these 13 samples into three categories, which was consistent with the chemotypes of those chromatograms. The method developed in this study provides a substantial foundation for the establishment of reasonable quality control standards for V. negundo seeds. This article is protected by copyright. All rights reserved.