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Leelawadee Techasatian - One of the best experts on this subject based on the ideXlab platform.
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Diaper rashes can indicate systemic conditions other than Diaper Dermatitis.
BMC dermatology, 2020Co-Authors: Sirirus Lebsing, Jitjira Chaiyarit, Leelawadee TechasatianAbstract:Although the majority of rashes in the Diaper area are caused by irritation from urine and feces, irritant Diaper Dermatitis; IDD, there are some less common but potentially serious cutaneous eruptions associated with systemic diseases that should not be discounted. This prospective descriptive study aimed to explore variation in cutaneous disease in the Diaper area. It was conducted as a prospective descriptive study between October 2016 and November 2019 in the pediatric department of a tertiary-level hospital. Three hundred consecutive patients with rashes in the Diaper area were enrolled. The most common diagnosed was IDD (125 cases; 41.7%), followed by rashes exacerbated by the Diaper (101 cases; 33.67%) and non-Diaper-related rashes (74 cases; 24.67%). Our finding suggests that when diagnosing rashes that occur in the Diaper area, general pediatricians should consider, in addition to IDD, the possibility of less-common conditions. The simultaneous presence of cutaneous lesions at other sites was linked to diagnoses of systemic diseases other than IDD, (P
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Diaper Dermatitis prevalence and associated factors in 2 university daycare centers
Journal of Primary Care & Community Health, 2020Co-Authors: Porntipa Suebsarakam, Jitjira Chaiyarit, Leelawadee TechasatianAbstract:Purpose: Diaper Dermatitis is uncommon in children older than 2 years because the majority of these children are Diaper independent. However, Diaper Dermatitis still occurs, especially in children in daycare settings. This study attempted to determine the prevalence of Diaper Dermatitis and its associated factors among children aged 2 to 4 years attending daycare centers. Cross-sectional analysis and tests for correlation were conducted to determine the factors associated with Diaper Dermatitis among the study population. Results: The prevalence of Diaper Dermatitis during the study period was 17.2%. Factors significantly correlated with the occurrence of Diaper Dermatitis were beginning toilet training later than 2 years of age (odds ratio [OR] = 2.84, 95% CI = 1.17-6.86, P = .02) and the use of oral antibiotics (OR = 15.92, 95%CI = 3.57-70.94, P < .001). Conclusion: Two major adjustable factors for preventing Diaper Dermatitis in the study population were toilet training before 2 years of age and avoiding the use of unnecessary oral antibiotics. These results may help in devising a preventive protocol for Diaper Dermatitis among this age group in the future.
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Diaper Dermatitis a survey of risk factors in thai children aged under 24 months
BMC Dermatology, 2019Co-Authors: Chonnakarn Sukhneewat, Jitjira Chaiyarit, Leelawadee TechasatianAbstract:To identify the prevalence and risk factors associated with Diaper Dermatitis in Thai children aged 1–24 months. This was a cross-sectional study of 1153 participants using structural questionnaires, which was conducted at Khon Kaen University Faculty of Medicine Pediatric department in Thailand. Univariate and multivariate logistic regression analyses were used to test the association between Diaper Dermatitis and its possible risk factors. The prevalence of Diaper Dermatitis among the study population was 36.1%, a rate which significantly decreased with age. The highest prevalence was found in subjects who were one to six months old. Risk factors that had a statistically significant association with Diaper Dermatitis in both univariate and multivariate analysis were i) Diaper changing fewer than three times/night, ii) previous episodes of Diaper rash, iii) using cloth Diapers, and iv) topical application of baby talcum powder to the Diaper area. Frequent Diaper changings during the daytime do not compensate for fewer changings during the night. Moreover, the use of baby talcum powder on the Diaper area significantly increased the risk of Diaper Dermatitis among the study population. These findings should be applied in future preventive strategies for Diaper Dermatitis in this age group.
David J. Atherton - One of the best experts on this subject based on the ideXlab platform.
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a review of the pathophysiology prevention and treatment of irritant Diaper Dermatitis
Current Medical Research and Opinion, 2004Co-Authors: David J. AthertonAbstract:SUMMARYIrritant Diaper Dermatitis (IDD) is a form of contact Dermatitis occurring in the Diaper area as a consequence of disruption of the barrier function of the skin through prolonged contact with faeces and urine. Despite advances in Diaper technology, it is a condition that still occurs regularly in young children. To combat this, barrier preparations can be used to protect the skin by coating the surface of the skin and/or by supplying lipids that can penetrate the intercellular spaces of the stratum corneum. In this review, the pathophysiology of IDD is outlined and its prevention and treatment are discussed, with particular reference to the role of emollients.
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The aetiology and management of irritant Diaper Dermatitis
Journal of the European Academy of Dermatology and Venereology, 2001Co-Authors: David J. AthertonAbstract:Irritant Diaper Dermatitis (IDD) is a common condition caused by the combination of wearing Diapers, and incontinence of urine and faeces. The available evidence suggests that maceration of the stratum corneum by water increases susceptibility to frictional damage, and epidermal permeation of irritants. The most important irritants underlying IDD appear to be digestive enzymes persisting in faeces, particularly when these are activated by a high pH.
Jitjira Chaiyarit - One of the best experts on this subject based on the ideXlab platform.
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Diaper rashes can indicate systemic conditions other than Diaper Dermatitis.
BMC dermatology, 2020Co-Authors: Sirirus Lebsing, Jitjira Chaiyarit, Leelawadee TechasatianAbstract:Although the majority of rashes in the Diaper area are caused by irritation from urine and feces, irritant Diaper Dermatitis; IDD, there are some less common but potentially serious cutaneous eruptions associated with systemic diseases that should not be discounted. This prospective descriptive study aimed to explore variation in cutaneous disease in the Diaper area. It was conducted as a prospective descriptive study between October 2016 and November 2019 in the pediatric department of a tertiary-level hospital. Three hundred consecutive patients with rashes in the Diaper area were enrolled. The most common diagnosed was IDD (125 cases; 41.7%), followed by rashes exacerbated by the Diaper (101 cases; 33.67%) and non-Diaper-related rashes (74 cases; 24.67%). Our finding suggests that when diagnosing rashes that occur in the Diaper area, general pediatricians should consider, in addition to IDD, the possibility of less-common conditions. The simultaneous presence of cutaneous lesions at other sites was linked to diagnoses of systemic diseases other than IDD, (P
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Diaper Dermatitis prevalence and associated factors in 2 university daycare centers
Journal of Primary Care & Community Health, 2020Co-Authors: Porntipa Suebsarakam, Jitjira Chaiyarit, Leelawadee TechasatianAbstract:Purpose: Diaper Dermatitis is uncommon in children older than 2 years because the majority of these children are Diaper independent. However, Diaper Dermatitis still occurs, especially in children in daycare settings. This study attempted to determine the prevalence of Diaper Dermatitis and its associated factors among children aged 2 to 4 years attending daycare centers. Cross-sectional analysis and tests for correlation were conducted to determine the factors associated with Diaper Dermatitis among the study population. Results: The prevalence of Diaper Dermatitis during the study period was 17.2%. Factors significantly correlated with the occurrence of Diaper Dermatitis were beginning toilet training later than 2 years of age (odds ratio [OR] = 2.84, 95% CI = 1.17-6.86, P = .02) and the use of oral antibiotics (OR = 15.92, 95%CI = 3.57-70.94, P < .001). Conclusion: Two major adjustable factors for preventing Diaper Dermatitis in the study population were toilet training before 2 years of age and avoiding the use of unnecessary oral antibiotics. These results may help in devising a preventive protocol for Diaper Dermatitis among this age group in the future.
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Diaper Dermatitis a survey of risk factors in thai children aged under 24 months
BMC Dermatology, 2019Co-Authors: Chonnakarn Sukhneewat, Jitjira Chaiyarit, Leelawadee TechasatianAbstract:To identify the prevalence and risk factors associated with Diaper Dermatitis in Thai children aged 1–24 months. This was a cross-sectional study of 1153 participants using structural questionnaires, which was conducted at Khon Kaen University Faculty of Medicine Pediatric department in Thailand. Univariate and multivariate logistic regression analyses were used to test the association between Diaper Dermatitis and its possible risk factors. The prevalence of Diaper Dermatitis among the study population was 36.1%, a rate which significantly decreased with age. The highest prevalence was found in subjects who were one to six months old. Risk factors that had a statistically significant association with Diaper Dermatitis in both univariate and multivariate analysis were i) Diaper changing fewer than three times/night, ii) previous episodes of Diaper rash, iii) using cloth Diapers, and iv) topical application of baby talcum powder to the Diaper area. Frequent Diaper changings during the daytime do not compensate for fewer changings during the night. Moreover, the use of baby talcum powder on the Diaper area significantly increased the risk of Diaper Dermatitis among the study population. These findings should be applied in future preventive strategies for Diaper Dermatitis in this age group.
Lawrence F. Eichenfield - One of the best experts on this subject based on the ideXlab platform.
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Diaper Dermatitis prevalence and severity global perspective on the impact of caregiver behavior
Pediatric Dermatology, 2020Co-Authors: Andrew N Carr, Alfred T. Lane, Lawrence F. Eichenfield, Thomas G Dewitt, Michael J Cork, Regina Folsterholst, Daniel Hohl, Amy S Paller, Larry K PickeringAbstract:Author(s): Carr, Andrew N; DeWitt, Thomas; Cork, Michael J; Eichenfield, Lawrence F; Folster-Holst, Regina; Hohl, Daniel; Lane, Alfred T; Paller, Amy; Pickering, Larry; Taieb, Alain; Cui, Tao Y; Xu, Zi G; Wang, Xeumin; Brink, Susanna; Niu, Yeuqing; Ogle, Julie; Odio, Mauricio; Gibb, Roger D | Abstract: OBJECTIVES:To compare prevalence and severity of Diaper Dermatitis (DD) in infants and toddlers (babies) across three countries (China, USA, and Germany), including Diapered skin measures and caregiver practices. METHODS:A cross-sectional study of 1791 babies (~600 from each country) was recruited at each clinical site. Based on regional toilet-training habits, exclusively Diaper-wearing infants were recruited between ages 2-8 months in China and 2-18 months in the USA and Germany. DD was measured, as well as skin pH, transepidermal water loss (TEWL), and relative humidity (RH) in the Diapered region. Caregiver habits were collected via a questionnaire and included information on hygienic practices. RESULTS:Diaper Dermatitis was highest in the perianal area, followed by the intertriginous, genital, and buttock regions. In general, DD was significantly lower in babies in China, highest in Germany, and intermediate in the USA. This rank ordering of DD by geography was also observed in baby age 2-8 months. The lower DD observed in China was associated with lower skin pH and TEWL on Diapered skin and decreased RH in the Diaper. Chinese caregivers had the highest rate of prophylactic topical product usage, the most robust cleaning of the Diapered area, lack of cleansing after urine-only Diaper changes, and Chinese infants spent the least time in an overnight Diaper. CONCLUSIONS:These data suggest caregiver behaviors including prophylactic use of topical products, thorough cleaning after stooling and reduced time in an overnight Diaper are associated with less DD, lower superficial skin pH, and enhanced skin barrier.
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Diaper Dermatitis: Clinical Characteristics and Differential Diagnosis
Pediatric Dermatology, 2014Co-Authors: Carrie C. Coughlin, Lawrence F. Eichenfield, Ilona J. FriedenAbstract:A diverse group of diseases can cause skin conditions in the Diaper area including those which are directly caused by Diapers or the Diaper environment, some which are not directly due to, but are worsened by, the wearing of Diapers, and those which are independent of the presence of the Diaper or its resulting environment. Many of these conditions are limited to this area of the skin, but others extend to skin outside this area, and some are signs of systemic disease. We review many of the important causes of eruptions in the Diaper area and emphasize key points in the differential diagnosis.
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absorption and efficacy of miconazole nitrate 0 25 ointment in infants with Diaper Dermatitis
Journal of Drugs in Dermatology, 2007Co-Authors: Lawrence F. Eichenfield, Melissa L BogenAbstract:Background: The potential for toxicity from systemic absorption of topical miconazole in infants is a concern. Objective: To assess the relative safety of 0.25% miconazole based on the amount absorbed through the skin of infants with Diaper Dermatitis after multiple applications. Methods: Of 24 infants with moderate to severe Diaper Dermatitis, 19 received 0.25% miconazole nitrate ointment and 5 received 2% miconazole nitrate cream for 7 days at each Diaper change and after bathing. Blood samples were collected prior to treatment and after 7 days. Results: In the 0.25% treatment group, blood concentrations of miconazole were nondetectable (<1 ng/mL) in 83% (15/18) and minimal (3.0 to 3.8 ng/mL) in 17% (3/18). Samples were missing for one patient. For the 5 infants in the 2% treatment group, miconazole concentration was nondetectable in 20% (1/5) and less than 7.4 ng/mL in 4 infants. No adverse events were noted. Conclusions: Systemic absorption of 0.25% miconazole nitrate ointment was minimal, demonstrating its safety in the treatment of moderate to severe Diaper Dermatitis.
Marlo Swanepoel - One of the best experts on this subject based on the ideXlab platform.
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A Randomised Pilot Study on the Efficacy of Milking Cream and a Homeopathic Complex Topical Cream on Diaper Dermatitis
AOSIS, 2013Co-Authors: Janice Pellow, Marlo SwanepoelAbstract:Diaper Dermatitis (DD) is an acute inflammation of the skin in the Diaper area and is the most common cutaneous disease among infants and children. Calendula officinalis, Atropa belladonna and Sulphuricum acidum are homeopathic remedies which have been purported to be beneficial in wound healing and conditions affecting the skin, however, to date, no research has been conducted on the use of these remedies for DD. The aim of this seven-day, double-blind, controlled pilot study was to assess the efficacy of milking cream and a homeopathic complex cream as topical treatments for DD. Forty children between the ages of three to 24 months with DD were recruited. The homeopathic complex cream (n= 20) or unmedicated milking cream (n = 20) was applied after every nappy change for seven days. Efficacy on the severity of symptoms and the percentage of area affected was assessed by means of the 4-Point Grading Scale and the Modified Lund and Browder Charts respectively, on days 1, 2, 4 and 7. The results revealed that both groups showed statistically-significant improvements on rash severity and the percentage of area affected between consecutive visits, as well as over the entire research study period. Trends indicated that the treatment group had a faster resolution of symptoms and outperformed the control in certain affected body regions. Preliminary findings suggest that both milking cream and the homeopathic complex cream may be effective alternative treatment options for DD, and further investigation is warranted
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A Randomised Pilot Study on the Efficacy of Milking Cream and a Homeopathic Complex Topical Cream on Diaper Dermatitis
AOSIS, 2013Co-Authors: Janice Pellow, Marlo SwanepoelAbstract:Diaper Dermatitis (DD) is an acute inflammation of the skin in the Diaper area and is the most common cutaneous disease among infants and children. Calendula officinalis, Atropa belladonna and Sulphuricum acidum are homeopathic remedies which have been purported to be beneficial in wound healing and conditions affecting the skin, however, to date, no research has been conducted on the use of these remedies for DD. The aim of this seven-day, double-blind, controlled pilot study was to assess the efficacy of milking cream and a homeopathic complex cream as topical treatments for DD. Forty children between the ages of three to 24 months with DD were recruited. The homeopathic complex cream (n = 20) or unmedicated milking cream (n = 20) was applied after every nappy change for seven days. Efficacy on the severity of symptoms and the percentage of area affected was assessed by means of the 4-Point Grading Scale and the Modified Lund and Browder Charts respectively, on days 1, 2, 4 and 7. The results revealed that both groups showed statistically-significant improvements on rash severity and the percentage of area affected between consecutive visits, as well as over the entire research study period. Trends indicated that the treatment group had a faster resolution of symptoms and outperformed the control in certain affected body regions. Preliminary findings suggest that both milking cream and the homeopathic complex cream may be effective alternative treatment options for DD, and further investigation is warranted. Luier Dermatitis (LD) is ‘n akute inflammasie van die vel in die luier area en is die algemeenste velsiekte onder babas en kleuters. Calendula officinalis, Atropa belladonna en Sulphuricum acidum is beweerde homeopatiese middels wat voordelig is in wondgenesing en ander velkondisies. Tot ophede is daar geen navorsing gedoen op die doeltreffendheid van die bogenoemde middels op LD nie. Die doelwit van die sewe dag, dubbele-blinde, beheerde-loodsstudie was om die doelteffendheid van melksalf en ‘n homeopatiese mengsel te evalueer as topikale behandelinge vir LD. Veertig babas tussen die ouderdomme van drie maande tot 24 maande was gewerf om deel te neem aan die studie. Die homeopatiese mengsel room (n = 20) of die melksalf (n = 20) was aangewend met elke luier vervanging vir sewe dae lank. Die doeltreffendheid van die room was beoordeel op dag 1, 2, 4 en 7 aan die erns van die simptome en die persentasie gebied wat geraak was, met behulp van ‘n 4-Punt Graderingsskaal en die Gewysigde Lund en Browder Grafiek onderskeidelik. Uitslae het getoon dat die behandelingsgroep en die kontrolegroep albei statistiese, beduidende verbeteringe getoon het op die erns van die uitslag en die persentasie gebied wat geraak is, tussen opeenvolgende besoeke sowel as die hele studie tydperk. Tendense dui daarop dat die behandelingsgroep ‘n vinniger oplossing van simptome getoon het en beter gevaar het as die kontrolegroep in sekere geaffekteerde liggaamstreke. Voorlopige bevindinge dui daarop dat beide melksalf en die homeopatiese mengsel room effektiewe, alternatiewe behandelings opsies vir LD is en dat verdere ondersoek geregverdig is