The Experts below are selected from a list of 123 Experts worldwide ranked by ideXlab platform
Saeed Asgary - One of the best experts on this subject based on the ideXlab platform.
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Repair of furcal perforation using a new Endodontic cement
Clinical Oral Investigations, 2010Co-Authors: Mohammad Samiee, Mohammad Jafar Eghbal, Masoud Parirokh, Fatemeh Mashhadi Abbas, Saeed AsgaryAbstract:The aim of this study was to compare the histologic response elicited by repairing furcal perforations with mineral trioxide aggregate (MTA) and a new Endodontic Material in the name of “calcium enriched mixture (CEM) cement” in dogs’ teeth. Thirty-four premolars were randomly divided into four groups: MTA ( n = 15), CEM ( n = 15), positive, and negative controls ( n = 4). Root canal therapy were carried out; perforations were made, and the furcation areas were then repaired with MTA or CEM cement. The animals were sacrificed after 3 months. The teeth and their adjacent structures were processed and stained with hematoxylin and eosin stain for histological evaluation. Chi-square test was used to evaluate hard tissue formation, and Mann–Whitney U test was used for the histological evaluation of inflammation. Specimens in positive controls showed severe inflammatory infiltration, prominent granulation tissue, and epithelial proliferation; negative controls demonstrated normal periodontal ligament without inflammatory reactions. Hard tissue formation was observed in all the specimens of the two experimental groups. In inflammatory evaluation, mild inflammation was detected in the experimental groups, and no statistically significant differences were observed between them. MTA and CEM cement showed similar favorable biological response in furcation perforation repair, especially in inducing the formation of cementum-like hard tissue.
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The Properties of a New Endodontic Material
Journal of endodontics, 2008Co-Authors: Saeed Asgary, Sima Shahabi, Tahereh Jafarzadeh, Sara Amini, Sanam KheiriehAbstract:The purpose of this study was to analyze the physical properties and chemical compositions of a new experimental cement (NEC) and compare them with mineral trioxide aggregate (MTA); pH, working time, setting time, dimensional changes following setting, flow, film thickness, and chemical composition of NEC and MTA were assessed. For chemical compositions, all specimens were imaged and analyzed by scanning electron microscopy and electron probe microanalysis (EPMA). The physical properties were performed according to ISO 6876:2001. Working time, pH, and dimensional changes of NEC and MTA showed similar results. Shorter setting time was obtained with the NEC compared with MTA (p < 0.05). The NEC showed more flow than MTA. In addition, the film thickness of the NEC was considerably less than the MTA (p < 0.01 and p < 0.001, respectively). EPMA investigations indicated that lime (CaO) was the dominant compound in NEC and MTA; however, other compounds were significantly different. It was concluded that the chemical composition of NEC is different compare with MTA; it can be concluded that the NEC exhibits acceptable physical properties.
Sanam Kheirieh - One of the best experts on this subject based on the ideXlab platform.
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The Properties of a New Endodontic Material
Journal of endodontics, 2008Co-Authors: Saeed Asgary, Sima Shahabi, Tahereh Jafarzadeh, Sara Amini, Sanam KheiriehAbstract:The purpose of this study was to analyze the physical properties and chemical compositions of a new experimental cement (NEC) and compare them with mineral trioxide aggregate (MTA); pH, working time, setting time, dimensional changes following setting, flow, film thickness, and chemical composition of NEC and MTA were assessed. For chemical compositions, all specimens were imaged and analyzed by scanning electron microscopy and electron probe microanalysis (EPMA). The physical properties were performed according to ISO 6876:2001. Working time, pH, and dimensional changes of NEC and MTA showed similar results. Shorter setting time was obtained with the NEC compared with MTA (p < 0.05). The NEC showed more flow than MTA. In addition, the film thickness of the NEC was considerably less than the MTA (p < 0.01 and p < 0.001, respectively). EPMA investigations indicated that lime (CaO) was the dominant compound in NEC and MTA; however, other compounds were significantly different. It was concluded that the chemical composition of NEC is different compare with MTA; it can be concluded that the NEC exhibits acceptable physical properties.
Lynne A. Opperman - One of the best experts on this subject based on the ideXlab platform.
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In vitro evaluation of dentinal tubule penetration and biomineralization ability of a new root-end filling Material.
Journal of endodontics, 2012Co-Authors: David C. Bird, Takashi Komabayashi, Lilly Guo, Lynne A. Opperman, Robert SpearsAbstract:Introduction Capasio is being developed as a new generation of Endodontic Material with potential use as a root-end filling Material. The aim of this study was to compare the ability of Capasio and mineral trioxide aggregate (MTA) to penetrate human dentinal tubules and examine the interaction of Capasio and MTA with a synthetic tissue fluid (STF) and root canal walls in extracted human teeth.
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Biocompatibility and Osteogenic Potential of New Generation Endodontic Materials Established by Using Primary Osteoblasts
Journal of endodontics, 2011Co-Authors: Jelani T. Washington, Robert Spears, Emet D. Schneiderman, Claudia R. Fernandez, Lynne A. OppermanAbstract:Abstract Introduction Generex A and Generex B (calcium silicate based), Capasio (calcium-phospho-alumino silicate based) along with Ceramicrete-D (magnesium phosphate based) are being introduced as a new generation of Endodontic Materials with the potential to facilitate bone healing. The aim of this study was to evaluate the biocompatibility and osteogenic potential of these new Materials by using primary osteoblasts. Methods Primary osteoblasts were prepared from rat calvaria and exposed to mineral trioxide aggregate (MTA), Generex A, Generex B, Capasio, and Ceramicrete-D prepared to standardized size and shape (n = 5). Trypan blue staining was used to evaluate cell viability from 1–6 days. Mineralization potential was evaluated by scanning electron microscopy for the presence of mineralized nodules. Data were analyzed by Kruskal-Wallis and Mann-Whitney U tests. Results Only Generex A and MTA allowed cell growth and proliferation throughout the experiment. There were statistically significant differences between groups throughout the experiment beginning on day 1. The greatest amount of cell growth was consistently observed with Generex A and MTA. There was no difference in mineralized nodule formation between any test Materials. Conclusions Generex A was the only new generation Endodontic Material that supported primary osteoblast growth; no Material besides MTA facilitated nodule formation.
Markus Haapasalo - One of the best experts on this subject based on the ideXlab platform.
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Antibiofilm Activity of Five Different Endodontic Filling Materials Used in Primary Teeth Using Confocal Laser Scanning Microscopy.
Pediatric dentistry, 2017Co-Authors: Katerine Jahnecke Pilownic, Markus Haapasalo, Ya Shen, Ceci Nunes Carvalho, Ana Regina Romano, Renata Dornelles Morgental, Fernanda Geraldo PappenAbstract:PURPOSE The purpose of this study was to evaluate the effect of five Endodontic Materials for primary teeth on in vitro mixed-species biofilms. METHODS Zinc oxide eugenol (ZOE) cement, Vitapex, Calen paste thickened with zinc oxide (ZO), pure calcium hydroxide (Ca(OH)2) paste, and iodoform were evaluated. Sterile water was used as a control. Mixed-species biofilm was incubated in anaerobic conditions for 21 days. The biofilm specimens were placed in contact with the Endodontic Materials for periods of seven and 30 days. The biofilm was studied by using confocal laser scanning microscopy. The cell viability ratio was calculated. The results were analyzed using analysis of variance and Tukey tests. RESULTS There was a statistically significant difference between groups at both seven and 30 days (F equals 73,073, P=0.00). After 30 days, 69 percent, 51 percent, and 35 percent of the biofilm volume fluoresced red, indicating the proportion of bacteria killed by iodoform, Vitapex, and ZOE cement, respectively. Calen plus ZO and pure Ca(OH)2 paste were the least effective Materials against the biofilms. CONCLUSIONS Pure iodoform paste and iodoform containing Vitapex were the most effective Materials against the biofilms. Vitapex appears to be a suitable Endodontic Material for primary teeth.
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physical properties and hydration behavior of a fast setting bioceramic Endodontic Material
BMC Oral Health, 2016Co-Authors: Yajua Guo, Ya She, Christophe Mobucho, Ahmed Hieawy, Zheju Wang, Ya Yang, Markus HaapasaloAbstract:To investigate the physical properties and the hydration behaviour of the fast-setting bioceramic iRoot FS Fast Set Root Repair Material (iRoot FS) and three other Endodontic cements. iRoot FS, Endosequence Root Repair Material Putty (ERRM Putty), gray and white mineral trioxide aggregate (G-MTA & W-MTA), and intermediate restorative Material (IRM) were evaluated. The setting time was measured using ANSI/ADA standards. Microhardness was evaluated using the Vickers indentation test. Compressive strength and porosity were investigated at 7 and 28 days. Differential scanning calorimetry (DSC) was employed for the hydration test. iRoot FS had the shortest setting time of the four bioceramic cements (p < .001). The microhardness values of iRoot FS, ERRM Putty and MTA increased at different rates over the 28 days period. At day one, ERRM Putty had the lowest microhardness of the bioceramic cements (p < .001), but reached the same level as MTA at 4, 7 and 28 days. The microhardness of iRoot FS was lower than that of W-MTA at 7 and 28 days (p < .05). The porosity of the Materials did not change after 7 days (p < .05). The compressive strength values at 28 days were significantly greater for all bioceramic groups compared to those at 7 days (p < .01). ERRM Putty had the highest compressive strength and the lowest porosity of the evaluated bioceramic cements (p < .05), followed by iRoot FS, W-MTA, and G-MTA, respectively. DSC showed that iRoot FS hydrated fastest, inducing an intense exothermic reaction. The ERRM Putty did not demonstrate a clear exothermic peak during the isothermal calorimetry test. iRoot FS had a faster setting time and hydrating process than the other bioceramic cements tested. The mechanical properties of iRoot FS, G-MTA and W-MTA were relatively similar.
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Physical properties and hydration behavior of a fast-setting bioceramic Endodontic Material
BMC oral health, 2016Co-Authors: Ya-juan Guo, Ahmed Hieawy, Ya Shen, Christophe Mobuchon, Zhejun Wang, Yan Yang, Markus HaapasaloAbstract:To investigate the physical properties and the hydration behaviour of the fast-setting bioceramic iRoot FS Fast Set Root Repair Material (iRoot FS) and three other Endodontic cements. iRoot FS, Endosequence Root Repair Material Putty (ERRM Putty), gray and white mineral trioxide aggregate (G-MTA & W-MTA), and intermediate restorative Material (IRM) were evaluated. The setting time was measured using ANSI/ADA standards. Microhardness was evaluated using the Vickers indentation test. Compressive strength and porosity were investigated at 7 and 28 days. Differential scanning calorimetry (DSC) was employed for the hydration test. iRoot FS had the shortest setting time of the four bioceramic cements (p
Robert Spears - One of the best experts on this subject based on the ideXlab platform.
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In vitro evaluation of dentinal tubule penetration and biomineralization ability of a new root-end filling Material.
Journal of endodontics, 2012Co-Authors: David C. Bird, Takashi Komabayashi, Lilly Guo, Lynne A. Opperman, Robert SpearsAbstract:Introduction Capasio is being developed as a new generation of Endodontic Material with potential use as a root-end filling Material. The aim of this study was to compare the ability of Capasio and mineral trioxide aggregate (MTA) to penetrate human dentinal tubules and examine the interaction of Capasio and MTA with a synthetic tissue fluid (STF) and root canal walls in extracted human teeth.
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Biocompatibility and Osteogenic Potential of New Generation Endodontic Materials Established by Using Primary Osteoblasts
Journal of endodontics, 2011Co-Authors: Jelani T. Washington, Robert Spears, Emet D. Schneiderman, Claudia R. Fernandez, Lynne A. OppermanAbstract:Abstract Introduction Generex A and Generex B (calcium silicate based), Capasio (calcium-phospho-alumino silicate based) along with Ceramicrete-D (magnesium phosphate based) are being introduced as a new generation of Endodontic Materials with the potential to facilitate bone healing. The aim of this study was to evaluate the biocompatibility and osteogenic potential of these new Materials by using primary osteoblasts. Methods Primary osteoblasts were prepared from rat calvaria and exposed to mineral trioxide aggregate (MTA), Generex A, Generex B, Capasio, and Ceramicrete-D prepared to standardized size and shape (n = 5). Trypan blue staining was used to evaluate cell viability from 1–6 days. Mineralization potential was evaluated by scanning electron microscopy for the presence of mineralized nodules. Data were analyzed by Kruskal-Wallis and Mann-Whitney U tests. Results Only Generex A and MTA allowed cell growth and proliferation throughout the experiment. There were statistically significant differences between groups throughout the experiment beginning on day 1. The greatest amount of cell growth was consistently observed with Generex A and MTA. There was no difference in mineralized nodule formation between any test Materials. Conclusions Generex A was the only new generation Endodontic Material that supported primary osteoblast growth; no Material besides MTA facilitated nodule formation.