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Mahmoud Torabinejad - One of the best experts on this subject based on the ideXlab platform.
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treatment of teeth with open apices using Mineral Trioxide Aggregate
Practical periodontics and aesthetic dentistry : PPAD, 2000Co-Authors: Shahrokh Shabahang, Mahmoud TorabinejadAbstract:Injuries to the dentition may ultimately result in the interruption of root development. If the pulp remains vital following trauma, this state should be maintained and root-end closure should be induced by apexogenesis. When the pulp is necrotic, the placement of an apical barrier can be utilized as an alternative to establish an environment that facilitates the closure of the apical opening. This article demonstrates the use of Mineral Trioxide Aggregate as an apical barrier material for root-end closure in the permanent teeth of three patients.
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clinical applications of Mineral Trioxide Aggregate
Journal of Endodontics, 1999Co-Authors: Mahmoud Torabinejad, Noah ChivianAbstract:An experimental material, Mineral Trioxide Aggregate (MTA), has recently been investigated as a potential alternative restorative material to the presently used materials in endodontics. Several in vitro and in vivo studies have shown that MTA prevents microleakage, is biocompatible, and promotes regeneration of the original tissues when it is placed in contact with the dental pulp or periradicular tissues. This article describes the clinical procedures for application of MTA in capping of pulps with reversible pulpitis, apexification, repair of root perforations nonsurgically and surgically, as well as its use as a root-end filling material.
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osteoblast biocompatibility of Mineral Trioxide Aggregate
Biomaterials, 1999Co-Authors: P J C Mitchell, Mahmoud Torabinejad, T Pitt R Ford, Fraser McdonaldAbstract:This study investigated the biocompatibility of variants of Mineral Trioxide Aggregate (MTA), by culturing human MG63 osteosarcoma cells in the presence of materials, observing cytomorphology and cell growth, and then assaying cytokine expression from the cells. Reference materials were employed. Cell growth was quantified by preparing samples (n=6) at 2, 4 and 7 days, for viewing by scanning electron microscopy and then scoring the amount of material that was covered by healthy cells. Subsequently, samples of culture media were tested using ELISA assays for expression of Interleukin (IL)-1α, IL-6, IL-8, IL-11 and macrophage colony stimulating factor (M-CSF). These assays were compared with controls where no material was present, and where media and fetal calf serum had not been exposed to cells. Results showed good cell growth on MTA. Expression of IL-6 from cells was only evident in the presence of MTA and Interpore 200. Interleukin-8 was expressed in high concentrations only in the presence of MTA. There was no evidence of expression of IL-1α or IL-11 with any material. Production of M-CSF was high for all materials. It appears that the variants of MTA are biocompatible and suitable for use in clinical trials.
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a comparative study of root end induction using osteogenic protein 1 calcium hydroxide and Mineral Trioxide Aggregate in dogs
Journal of Endodontics, 1999Co-Authors: Shahrokh Shabahang, Hamid R Abedi, Mahmoud Torabinejad, Philip P Oyne, Paul J McmillaAbstract:Calcium hydroxide has been the material of choice for apexification. The purpose of this study was to compare the efficacy of osteogenic protein-1 and Mineral Trioxide Aggregate with that of calcium hydroxide in the formation of hard tissue in immature roots of dogs. Sixty-four roots of premolars were used. After induction of periradicular lesions, the canals were debrided and filled with calcium hydroxide for 1 wk. After the removal of calcium hydroxide, the root canals received one of the treatment materials in a balanced design. The animals were euthanized 12 wk later. The degree of hard tissue formation and amount of inflammation were evaluated histomorphically. Data were statistically evaluated using ANOVA, x 2 , and Kruskal-Wallis. Mineral Trioxide Aggregate produced apical hard tissue formation with significantly greater consistency. The difference in the amount of hard tissue produced among the three test materials was not statistically significant. Furthermore, the degree of inflammation was not significantly different between the various test groups.
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cellular response to Mineral Trioxide Aggregate
Journal of Endodontics, 1998Co-Authors: Eng Tiong Koh, Thomas Pitt R Ford, Fraser Mcdonald, Mahmoud TorabinejadAbstract:This investigation studied the cytomorphology of osteoblasts in the presence of Mineral Trioxide Aggregate (MTA) and examined cytokine production. MTA and Intermediate Restorative Material (IRM) were prepared and placed in separate Petri dishes. Osteoblasts (cell-line MG-63), grown to confluence in Hams F12/Dulbecco's modified Eagle's medium, were seeded into the dishes, which were incubated for 1 to 7 days. The specimens were viewed by scanning electron microscopy. For cytokine evaluation, cells were grown either alone or in other dishes containing the test materials for 1 to 144 h. Media were removed for ELISA analysis of interleukin (IL)-1α, IL-1β, IL-6, and macrophage colony-stimulating factor. Scanning electron microscopy revealed healthy cells in contact with MTA at 1 and 3 days; in contrast, cells in the presence of IRM appeared rounded. The ELISA assays revealed raised levels of all ILs at all periods when cells were grown in the presence of MTA; in contrast, cells grown alone or with IRM produced undetectable amounts. The macrophage colony-stimulating factor was produced by cells irrespective of the group. It seems that MTA offers a biologically active substrate for bone cells and stimulates IL production.
Johannes Mente - One of the best experts on this subject based on the ideXlab platform.
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outcome of orthograde retreatment after failed apicoectomy use of a Mineral Trioxide Aggregate apical plug
Journal of Endodontics, 2015Co-Authors: Johannes Mente, Annemarie Michel, Holger Gehrig, Daniel Saure, Thorsten PfefferleAbstract:Abstract Introduction This controlled, single-center historic cohort study project evaluates treatment outcomes of a nonsurgical treatment approach after failed apicoectomy. Methods The treatment outcomes of nonsurgical retreatment after a failed apicoectomy were evaluated clinically and radiographically. The study cohort consisted of teeth that had received primary root canal treatment and subsequent apicoectomy elsewhere before the patients presented with post-treatment disease. Orthograde retreatment and obturation using an apical Mineral Trioxide Aggregate plug was performed by postgraduate students and endodontic specialists in 25 cases between 2004 and 2012. Pre-, intra-, and postoperative information and the potential effect on the retreatment outcome were evaluated and statistically analyzed using the chi-square test. Results Twenty-two patients with 23 teeth attended the follow-up examinations (recall rate = 92%). The follow-up periods ranged from 12 to 102 months (median = 35 months). Twenty teeth (87%) were classified as “success,” and 3 teeth were considered (17%) “failure.” The chi-square test confirmed that the preoperative factor “number of roots” had a statistically significant effect on treatment outcome (odds ratio = 0.08; 95% confidence interval, 0–1.76; P = .03). The factor “tooth location” was of borderline significance (odds ratio = 0.1; 95% confidence interval, 0–2.14; P = .05). Conclusions The results of the present study suggest that orthograde retreatment combined with orthograde placement of an apical Mineral Trioxide Aggregate plug is a promising long-term treatment option for teeth with postsurgical pathosis. The success rates were higher for single-rooted teeth. The use of cone-beam computed tomographic imaging in cases of inconclusive periapical radiographs is recommended to minimize the risk of misinterpretation when assessing treatment outcome.
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Mineral Trioxide Aggregate or calcium hydroxide direct pulp capping an analysis of the clinical treatment outcome
Journal of Endodontics, 2010Co-Authors: Johannes Mente, Martin Jea Koch, Jens Dreyhaup, Hans Joerg Staehle, Eate Geletneky, Marc Ohle, Paul Georg Friedrich Ding, Diana Wolff, Nicolas Marti, Thorste PfefferleAbstract:Abstract Introduction The use of Mineral Trioxide Aggregate (MTA) might improve the prognosis of teeth after pulp exposure. The treatment outcome of teeth after direct pulp capping, either with Mineral Trioxide Aggregate (MTA) or calcium hydroxide (controls), was investigated, taking into account possible confounding factors. Methods One hundred forty-nine patients treated between 2001 and 2006 who received direct pulp capping treatment in 167 teeth met the inclusion criteria. Treatment was performed by supervised undergraduate students (72%) and dentists (28%). Assessment of clinical and radiographic outcomes was performed by calibrated examiners 12–80 months after treatment (median, 27 months). Results One hundred eight patients (122 treated teeth) were available for follow-up (72.5% recall rate). A successful outcome was recorded for 78% of teeth (54 of 69) in the MTA group and for 60% of teeth (32 of 53) in the the calcium hydroxide group. The univariate analysis (generalized estimation equations model [GEE model] showed a significant difference in the success rate (odds ratio [OR], 2.36; 95% confidence interval [CI], 1.05–5.32; P = .04). In the multiple analysis (GEE model), the OR is marginally inside the nonsignificant range (OR, 0.43; 95% CI, 0.19–1.02; P = .05) when conspicuous confounding factors are stabilized (univariate analysis). Multiple analysis showed that teeth that were permanently restored ≥2 days after capping had a significantly worse prognosis in both groups (OR, 0.24; 95% CI, 0.09–0.66; P = .01). Conclusions MTA appears to be more effective than calcium hydroxide for maintaining long-term pulp vitality after direct pulp capping. The immediate and definitive restoration of teeth after direct pulp capping should always be aimed for.
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treatment outcome of Mineral Trioxide Aggregate repair of root perforations
Journal of Endodontics, 2010Co-Authors: Johannes Mente, Thorsten Pfefferle, Nathalie Hage, Martin Jean Koch, Beate Geletneky, Jens Dreyhaupt, Nicolas Martin, Hans Joerg StaehleAbstract:Abstract Introduction The use of biocompatible materials like Mineral Trioxide Aggregate (MTA) may improve the prognosis of teeth with root perforations. Methods The treatment outcome of root perforations repaired between 2000 and 2006 with MTA was investigated. Twenty-six patients received treatment with MTA in 26 teeth with root perforations. Treatment was performed by supervised undergraduate students (29%), general dentists (52%), or dentists who had focused on endodontics (19%). Perforation repair by all treatment providers was performed using a dental operating microscope. Calibrated examiners assessed clinical and radiographic outcome 12 to 65 months after treatment (median 33 months, 81% recall rate). Pre-, intra-, and postoperative information relating to potential prognostic factors was evaluated. Results Of 21 teeth examined, 18 teeth (86%) were classified as healed. None of the analyzed potential prognostic factors had a significant effect on the outcome. Conclusions MTA appears to provide a biocompatible and long-term effective seal for root perforations in all parts of the root.
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Mineral Trioxide Aggregate apical plugs in teeth with open apical foramina a retrospective analysis of treatment outcome
Journal of Endodontics, 2009Co-Authors: Johannes Mente, Nathalie Hage, Thorste Pfefferle, Martin Jea Koch, Jens Dreyhaup, Hans Joerg Staehle, Shimo FriedmaAbstract:Abstract Introduction Teeth with open apical foramina present a challenge during root canal treatment, and little is known about the clinical outcome of treatment in such teeth. This retrospective study assessed healing of teeth with open apices managed by the placement of Mineral Trioxide Aggregate apical plugs. Methods Seventy-two patients with 78 teeth with apical resorption or excessive apical enlargement, treated between 2000 and 2006, were contacted for follow-up examination 12 to 68 months after treatment (median 30.9 months). Treatments were provided by supervised undergraduate students (27%), general dentists (32%), or dentists who had focused on endodontics (41%). The outcome based on clinical and radiographic criteria was assessed by calibrated examiners and dichotomized as “healed” or “disease.” Results Of 56 teeth examined (72% recall), 84% were healed. Teeth without or with preoperative periapical radiolucency had a healed rate of 100% and 78%, respectively. None of the variables analyzed had a significant effect on the outcome. Conclusion The results supported the management of open apical foramina with Mineral Trioxide Aggregate apical plugs.
Ruy Cesar Camargo Abdo - One of the best experts on this subject based on the ideXlab platform.
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the effectiveness of Mineral Trioxide Aggregate calcium hydroxide and formocresol for pulpotomies in primary teeth
International Endodontic Journal, 2008Co-Authors: Ana Beatriz Silveira Moretti, Thais Marchini De Oliveira, Vivien Thiemy Sakai, Carlos Ferreira Dos Santos, Maria Aparecida De Andrade Moreira Machado, A P C Fornetti, Ruy Cesar Camargo AbdoAbstract:AIM: To compare the effectiveness of Mineral Trioxide Aggregate (MTA), calcium hydroxide (CH) and formocresol (FC) as pulp dressing agents in carious primary teeth. METHODOLOGY: Forty-five primary mandibular molars with dental caries in 23 children [AUTHOR QUERY: How many children?] between 5 and 9 years old were treated by a conventional pulpotomy technique. The teeth were randomly assigned to the experimental (CH or MTA) or control (FC) groups. After coronal pulp removal and haemostasis, remaining pulp tissue was covered with MTA paste or CH powder in the experimental groups. In the control group, diluted FC was placed with a cotton pellet over the pulp tissue for 5 min and removed; the pulp tissue was then covered with zinc oxide-eugenol (ZOE) paste. All teeth were restored with reinforced ZOE base and resin modified glass-ionomer cement. Clinical and radiographic successes and failures were recorded at 3, 6, 12, 18 and 24 month follow-up. RESULTS: Forty-three teeth were available for follow-up. In the FC and MTA groups, 100% of the available teeth were clinically and radiographically successful at all follow-up appointments; dentine bridge formation could be detected in 29% of the teeth treated with MTA. In the CH group, 64% of the teeth presented clinical and radiographic failures detected throughout the follow-up period, and internal resorption was a frequent radiographic finding. CONCLUSIONS: Mineral Trioxide Aggregate was superior to CH and equally as effective as FC as a pulpotomy dressing in primary mandibular molars. Internal resorption was the most common radiographic finding up to 24 month after pulpotomies performed with CH.
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repair of furcal perforation treated with Mineral Trioxide Aggregate in a primary molar tooth 20 month follow up
Journal of dentistry for children, 2008Co-Authors: Thais Marchini De Oliveira, Vivien Thiemy Sakai, Carlos Ferreira Dos Santos, Maria Aparecida De Andrade Moreira Machado, Thiago Cruvinel Da Silva, Ruy Cesar Camargo AbdoAbstract:Furcal perforations may occur during access opening of the pulp chamber or cavity preparation. The perforation can cause an inflammatory reaction in the periodontal ligament. Management of these iatrogenic accidents can pose a significant clinical challenge, mainly when they occur in primary teeth. Current developments in the techniques and materials utilized for root perforation repair have enhanced this procedure's prognosis. Recently, Mineral Trioxide Aggregate (MTA) has been used for several dental purposes. This biocompatible material promotes bone healing and elimination of clinical symptoms. The purpose of this case report was to describe the treatment of a furcal perforation using Mineral Trioxide Aggregate (MTA) in a primary molar tooth. After 20 months, the tooth was asymptomatic. The radiolucent image had disappeared and bone formation at the furcation area had been observed, suggesting healing of the underlying periodontal tissues. Therefore, MTA may be considered an alternative option for the repair of furcal perforation in primary teeth, prolonging the longevity of these dental elements.
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Mineral Trioxide Aggregate pulpotomy of a primary second molar in a patient with agenesis of the permanent successor
International Endodontic Journal, 2007Co-Authors: Ana Beatriz Silveira Moretti, Thais Marchini De Oliveira, Vivien Thiemy Sakai, Carlos Ferreira Dos Santos, Maria Aparecida De Andrade Moreira Machado, Ruy Cesar Camargo AbdoAbstract:Moretti ABS, Oliveira TM, Sakai VT, Santos CF, Machado MAAM, Abdo RCC. Mineral Trioxide Aggregate pulpotomy of a primary second molar in a patient with agenesis of the permanent successor. International Endodontic Journal, 40, 738–745, 2007. Aim To describe a pulpotomy with Mineral Trioxide Aggregate in a primary second molar with no permanent successor. Summary Coronal pulpotomy was performed on a carious primary molar with no permanent successor in a 7-year-old child. Follow-up examinations 24 months later revealed that the treatment was successful in preserving the tooth and the vitality of its pulp. Key learning point Mineral Trioxide Aggregate might be considered as an alternative wound dressing for pulpotomy in primary molars, preserving pulp vitality and prolonging the useful life of the tooth.
Thomas Pitt R Ford - One of the best experts on this subject based on the ideXlab platform.
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cellular response to Mineral Trioxide Aggregate
Journal of Endodontics, 1998Co-Authors: Eng Tiong Koh, Thomas Pitt R Ford, Fraser Mcdonald, Mahmoud TorabinejadAbstract:This investigation studied the cytomorphology of osteoblasts in the presence of Mineral Trioxide Aggregate (MTA) and examined cytokine production. MTA and Intermediate Restorative Material (IRM) were prepared and placed in separate Petri dishes. Osteoblasts (cell-line MG-63), grown to confluence in Hams F12/Dulbecco's modified Eagle's medium, were seeded into the dishes, which were incubated for 1 to 7 days. The specimens were viewed by scanning electron microscopy. For cytokine evaluation, cells were grown either alone or in other dishes containing the test materials for 1 to 144 h. Media were removed for ELISA analysis of interleukin (IL)-1α, IL-1β, IL-6, and macrophage colony-stimulating factor. Scanning electron microscopy revealed healthy cells in contact with MTA at 1 and 3 days; in contrast, cells in the presence of IRM appeared rounded. The ELISA assays revealed raised levels of all ILs at all periods when cells were grown in the presence of MTA; in contrast, cells grown alone or with IRM produced undetectable amounts. The macrophage colony-stimulating factor was produced by cells irrespective of the group. It seems that MTA offers a biologically active substrate for bone cells and stimulates IL production.
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using Mineral Trioxide Aggregate as a pulp capping material
Journal of the American Dental Association, 1996Co-Authors: Thomas Pitt R Ford, Hamid R Abedi, Leif K Bakland, Mahmoud Torabinejad, Stalin P KariyawasamAbstract:This study examined the dental pulp responses in monkeys to Mineral Trioxide Aggregate, or MTA, and a calcium hydroxide preparation when used as pulp-capping materials. After the pulps of 12 mandibular incisors were exposed with a No. 1 round bur, they were capped with either MTA or the calcium hydroxide preparation. After five months, the authors noted no pulpal inflammation in five of six samples capped with MTA, and all six pulps in this group had a complete dentin bridge. In contrast, all of the pulps capped with the calcium hydroxide preparation showed pulpal inflammation, and bridge formation occurred in only two samples. Based on these results, it appears that MTA has the potential to be used as a pulp-capping material during vital pulp therapy.
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use of Mineral Trioxide Aggregate for repair of furcal perforations
Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 1995Co-Authors: Thomas Pitt R Ford, Mahmoud Torabinejad, Douglas J Mckendry, Chanui Hong, Stalin P KariyawasamAbstract:The histologic response to intentional perforation in the furcations of 28 mandibular premolars in seven dogs was investigated. In half the teeth, the perforations were repaired immediately with either amalgam or Mineral Trioxide Aggregate; in the rest the perforations were left open to salivary contamination before repair. All repaired perforations were left for 4 months before histologic examination of vertical sections through the site. In the immediately repaired group, all the amalgam specimens were associated with inflammation, whereas only one of six with Mineral Trioxide Aggregate was; further, the five noninflamed Mineral Trioxide Aggregate specimens had some cementum over the repair material. In the delayed group, all the amalgam specimens were associated with inflammation; in contrast only four of seven filled with the Aggregate were inflamed. On the basis of these results, it appears that Mineral Trioxide Aggregate is a far more suitable material than amalgam for perforation repair, particularly when used immediately after perforation.
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bacterial leakage of Mineral Trioxide Aggregate as a root end filling material
Journal of Endodontics, 1995Co-Authors: M Torabinejad, Akbar Falah Rastegar, James D Kettering, Thomas Pitt R FordAbstract:Previous dye leakage studies have shown that Mineral Trioxide Aggregate leaks significantly less than other commonly used root-end filling materials. This study determined the time needed for Staphylococcus epidermidis to penetrate a 3-mm thickness of amalgam, Super-EBA, Intermediate Restorative Material (IRM), or Mineral Trioxide Aggregate (MTA) as root-end filling materials. Fifty-six single-rooted extracted human teeth were cleaned and shaped using a step-back technique. Following root-end resection, 48 root-end cavities were filled with amalgam, Super-EBA, IRM, or MTA. Four root-end cavities were filled with thermoplasticized gutta-percha without a root canal sealer (+ control), and another four were filled with sticky wax covered with two layers of nail polish (− control). After attaching the teeth to plastic caps of 12-ml plastic vials and placing the root ends into phenol red broth, the set-ups were sterilized overnight with ethylene dioxide gas. A tenth of a microliter of broth containing S. epidermidis was placed into the root canal of 46 teeth (40 experimental, 3 positive, and 3 negative control groups). In addition, the root canals of two teeth with test root-end filling materials and one tooth from the positive and negative control groups were filled with sterile saline. The number of days required for the test bacteria to penetrate various root-end filling materials was determined. Most samples whose apical 3 mm were filled with amalgam, Super-EBA, or IRM began leaking at 6 to 57 days. In contrast, the majority of samples whose root ends were filled with MTA did not show any leakage throughout the experimental period (90 days) in this study. Statistical analysis of the data showed no significant difference between the leakage of amalgam, Super-EBA, and IRM. However, MTA leaked significantly less than other root-end filling materials maintained under test conditions for 90 days in this experiment (p
T Pitt R Ford - One of the best experts on this subject based on the ideXlab platform.
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Mineral Trioxide Aggregate a review of the constituents and biological properties of the material
International Endodontic Journal, 2006Co-Authors: Josette Camilleri, T Pitt R FordAbstract:Camilleri J, Pitt Ford TR. Mineral Trioxide Aggregate: a review of the constituents and biological properties of the material. International Endodontic Journal, 39, 747–754, 2006. This paper reviews the literature on the constituents and biocompatibility of Mineral Trioxide Aggregate (MTA). A Medline search was conducted. The first publication on the material was in November 1993. The Medline search identified 206 papers published from November 1993 to August 2005. Specific searches on constituents and biocompatibility of Mineral Trioxide Aggregate, however, yielded few publications. Initially all abstracts were read to identify which fitted one of the two categories required for this review, constituents or biocompatibility. Based on this assessment and a review of the papers, 13 were included in the constituent category and 53 in the biocompatibility category. Relatively few articles addressed the constituents of MTA, whilst cytological evaluation was the most widely used biocompatibility test.
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biocompatibility of two commercial forms of Mineral Trioxide Aggregate
International Endodontic Journal, 2004Co-Authors: Josette Camilleri, Franco E. Montesin, Fraser Mcdonald, S Papaioannou, T Pitt R FordAbstract:Aim To examine the biocompatibility of two commercial forms of Mineral Trioxide Aggregate (MTA), by evaluating the morphology of an established cell line. Methodology The two cements were cast on glass cover slips and cured for 1 or 28 days. Saos-2 osteosarcoma cells were trypsinized and seeded at a density of 1 × 105 cells and were then placed in medium over the material-coated coverslips for 1, 5 and 7 days. After these time intervals the media were discarded and the cells fixed. Cell morphological investigation was performed by scanning electron microscopy at various magnifications ranging from × 250 to× 500. The biocompatibility of cement constituents, alusilicate flux and bismuth oxide was also investigated. Results All cement samples cured for 1 day showed a confluent cell monolayer after 5 and 7 days. The response to both materials was similar. Materials cured for 28 days showed incomplete cell confluence after 1 and 5 days. Alusilicate flux and bismuth oxide did not demonstrate biocompatibility. Conclusions The 1-day cured samples of two commercial forms of MTA showed good biocompatibility. However, the 28-day cured samples were less biocompatible after 1 and 5 days.
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osteoblast biocompatibility of Mineral Trioxide Aggregate
Biomaterials, 1999Co-Authors: P J C Mitchell, Mahmoud Torabinejad, T Pitt R Ford, Fraser McdonaldAbstract:This study investigated the biocompatibility of variants of Mineral Trioxide Aggregate (MTA), by culturing human MG63 osteosarcoma cells in the presence of materials, observing cytomorphology and cell growth, and then assaying cytokine expression from the cells. Reference materials were employed. Cell growth was quantified by preparing samples (n=6) at 2, 4 and 7 days, for viewing by scanning electron microscopy and then scoring the amount of material that was covered by healthy cells. Subsequently, samples of culture media were tested using ELISA assays for expression of Interleukin (IL)-1α, IL-6, IL-8, IL-11 and macrophage colony stimulating factor (M-CSF). These assays were compared with controls where no material was present, and where media and fetal calf serum had not been exposed to cells. Results showed good cell growth on MTA. Expression of IL-6 from cells was only evident in the presence of MTA and Interpore 200. Interleukin-8 was expressed in high concentrations only in the presence of MTA. There was no evidence of expression of IL-1α or IL-11 with any material. Production of M-CSF was high for all materials. It appears that the variants of MTA are biocompatible and suitable for use in clinical trials.
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sealing ability of a Mineral Trioxide Aggregate when used as a root end filling material
Journal of Endodontics, 1993Co-Authors: Mahmoud Torabinejad, Timothy F Watson, T Pitt R FordAbstract:This in vitro study used rhodamine B fluorescent dye and a confocal microscope to evaluate the sealing ability of amalgam, super EBA, and a Mineral Trioxide Aggregate when used as root end filling materials. Thirty single-canal teeth were cleaned, shaped, and obturated with gutta-percha and root canal sealer. After application of nail polish to the external surface, the apical 3 mm of each root was resected and 3-mm deep root end preparations were made. The roots were randomly divided into three groups and the root end preparations filled with the experimental materials. All roots were then exposed to an aqueous solution of rhodamine B fluorescent dye for 24 h, longitudinally sectioned, and the extent of dye penetration measured using a confocal microscope. Statistical analysis showed that the Mineral Trioxide Aggregate leaked significantly less than amalgam and super EBA.