Left Ventricular Dyssynchrony

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Ernst E Van Der Wall - One of the best experts on this subject based on the ideXlab platform.

  • Comparison between tissue Doppler imaging and velocity-encoded magnetic resonance imaging for measurement of myocardial velocities, assessment of Left Ventricular Dyssynchrony, and estimation of Left Ventricular filling pressures in patients with isc
    American Journal of Cardiology, 2008
    Co-Authors: Nina Ajmone Marsan, Martin J Schalij, Eduard R Holman, Ernst E Van Der Wall, Jos J.m. Westenberg, Laurens F. Tops, Claudia Ypenburg, J.h.c. Reiber, Albert De Roos, Jos R.t.c. Roelandt
    Abstract:

    Velocity-encoded magnetic resonance imaging (VE-MRI), commonly used to perform flow measurements, can be applied for myocardial velocity analysis, similar to tissue Doppler imaging (TDI). In this study, a comparison between VE-MRI and TDI was performed for the assessment of Left Ventricular Dyssynchrony and Left Ventricular filling pressures. Ten healthy volunteers and 22 patients with heart failure secondary to ischemic cardiomyopathy underwent both VE-MRI and TDI. Longitudinal myocardial peak systolic and diastolic velocities and time to peak systolic velocity (Ts) were measured with both techniques at the level of Left Ventricular septum and lateral wall. To quantify Left Ventricular Dyssynchrony, the delay in Ts between basal septum and lateral wall was calculated (SLD) and patients were categorized into 3 groups: minimal (SLD 60 ms) Left Ventricular Dyssynchrony. The ratio of transmitral E wave velocity and mitral annulus septal early velocity (E/E' ratio) was also assessed, and patients were divided into 3 groups: normal (E/E' 15) Left Ventricular filling pressures. Excellent correlations were observed for peak systolic velocity and peak diastolic velocity (r = 0.95, p

  • Left Ventricular Dyssynchrony acutely after myocardial infarction predicts Left Ventricular remodeling
    Journal of the American College of Cardiology, 2007
    Co-Authors: Sjoerd A Mollema, Eduard R Holman, Eric Boersma, Ernst E Van Der Wall, Gabe B. Bleeker, Su San Liem, Matthew S Suffoletto, Bas L Van Der Hoeven, Nico R Van De Veire, Martin J Schalij
    Abstract:

    Objectives We sought to identify predictors of Left Ventricular (LV) remodeling after acute myocardial infarction. Background Left Ventricular remodeling after myocardial infarction is associated with an adverse long-term prognosis. Early identification of patients prone to LV remodeling is needed to optimize therapeutic management. Methods A total of 178 consecutive patients presenting with acute myocardial infarction who underwent primary percutaneous coronary intervention were included. Within 48 h of intervention, 2-dimensional echocardiography was performed to assess LV volumes, LV ejection fraction (LVEF), wall motion score index, Left atrial dimension, E/E′ ratio, and severity of mitral regurgitation. Left Ventricular Dyssynchrony was determined using speckle-tracking radial strain analysis. At 6-month follow-up, LV volumes, LVEF, and severity of mitral regurgitation were reassessed. Results Patients showing LV remodeling at 6-month follow-up (20%) had comparable baseline characteristics to patients without LV remodeling (80%), except for higher peak troponin T levels (p Conclusions Left Ventricular Dyssynchrony immediately after acute myocardial infarction predicts LV remodeling at 6-month follow-up.

  • assessment of Left Ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
    Journal of the American College of Cardiology, 2006
    Co-Authors: Jos J.m. Westenberg, Martin J Schalij, Eduard R Holman, Ernst E Van Der Wall, Gabe B. Bleeker, Albert De Roos, Rob J Van Der Geest, Hildo J Lamb, J.h.c. Reiber
    Abstract:

    OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for Left Ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that intraVentricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study intraVentricular Dyssynchrony. RESULTS: Left Ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.

  • Tissue Doppler imaging to assess Left Ventricular Dyssynchrony and resynchronization therapy.
    European Journal of Echocardiography, 2005
    Co-Authors: Gabe B. Bleeker, Martin J Schalij, Ernst E Van Der Wall
    Abstract:

    We describe the use of tissue Doppler imaging to assess Left Ventricular Dyssynchrony and subsequent resynchronization in a patient with end-stage heart failure undergoing cardiac resynchronization therapy.

  • relationship between qrs duration and Left Ventricular Dyssynchrony in patients with end stage heart failure
    Journal of Cardiovascular Electrophysiology, 2004
    Co-Authors: B Gabe M D Bleeker, Martin J Schalij, G Sander M D Molhoek, Harriette F Verwey, Eduard R Holman, Eric Boersma, Paul Steendijk, Ernst E Van Der Wall
    Abstract:

    Introduction: Patients with end-stage heart failure and a wide QRS complex are considered candidates for cardiac resynchronization therapy (CRT). However, 20% to 30% of patients do not respond to CRT. Lack of Left Ventricular Dyssynchrony may explain the nonresponse. Accordingly, we evaluated the presence of Left Ventricular Dyssynchrony using tissue Doppler imaging (TDI) in 90 consecutive patients with heart failure. Methods and Results: Ninety patients with severe heart failure (Left Ventricular ejection fraction 150 ms). All patients underwent TDI to assess Left Ventricular Dyssynchrony. Extensive Left Ventricular Dyssynchrony was defined as an electromechanical delay on TDI between the septum and lateral wall, the so-called septal-to-lateral delay, of >60 ms. Severe Dyssynchrony was observed in 27% of patients with narrow QRS complex, 60% with intermediate QRS duration, and 70% with wide QRS complex. No relation existed between QRS duration and septal-to-lateral delay. Conclusion: From 30% to 40% of heart failure patients with QRS duration >120 ms do not exhibit Left Ventricular Dyssynchrony, which may explain the nonresponse to CRT. Alternatively, 27% of patients with heart failure and a narrow QRS complex show significant Left Ventricular Dyssynchrony and may be candidates for CRT. (J Cardiovasc Electrophysiol, Vol. 15, pp. 544-549, May 2004)

Martin J Schalij - One of the best experts on this subject based on the ideXlab platform.

  • Comparison between tissue Doppler imaging and velocity-encoded magnetic resonance imaging for measurement of myocardial velocities, assessment of Left Ventricular Dyssynchrony, and estimation of Left Ventricular filling pressures in patients with isc
    American Journal of Cardiology, 2008
    Co-Authors: Nina Ajmone Marsan, Martin J Schalij, Eduard R Holman, Ernst E Van Der Wall, Jos J.m. Westenberg, Laurens F. Tops, Claudia Ypenburg, J.h.c. Reiber, Albert De Roos, Jos R.t.c. Roelandt
    Abstract:

    Velocity-encoded magnetic resonance imaging (VE-MRI), commonly used to perform flow measurements, can be applied for myocardial velocity analysis, similar to tissue Doppler imaging (TDI). In this study, a comparison between VE-MRI and TDI was performed for the assessment of Left Ventricular Dyssynchrony and Left Ventricular filling pressures. Ten healthy volunteers and 22 patients with heart failure secondary to ischemic cardiomyopathy underwent both VE-MRI and TDI. Longitudinal myocardial peak systolic and diastolic velocities and time to peak systolic velocity (Ts) were measured with both techniques at the level of Left Ventricular septum and lateral wall. To quantify Left Ventricular Dyssynchrony, the delay in Ts between basal septum and lateral wall was calculated (SLD) and patients were categorized into 3 groups: minimal (SLD 60 ms) Left Ventricular Dyssynchrony. The ratio of transmitral E wave velocity and mitral annulus septal early velocity (E/E' ratio) was also assessed, and patients were divided into 3 groups: normal (E/E' 15) Left Ventricular filling pressures. Excellent correlations were observed for peak systolic velocity and peak diastolic velocity (r = 0.95, p

  • Left Ventricular Dyssynchrony acutely after myocardial infarction predicts Left Ventricular remodeling
    Journal of the American College of Cardiology, 2007
    Co-Authors: Sjoerd A Mollema, Eduard R Holman, Eric Boersma, Ernst E Van Der Wall, Gabe B. Bleeker, Su San Liem, Matthew S Suffoletto, Bas L Van Der Hoeven, Nico R Van De Veire, Martin J Schalij
    Abstract:

    Objectives We sought to identify predictors of Left Ventricular (LV) remodeling after acute myocardial infarction. Background Left Ventricular remodeling after myocardial infarction is associated with an adverse long-term prognosis. Early identification of patients prone to LV remodeling is needed to optimize therapeutic management. Methods A total of 178 consecutive patients presenting with acute myocardial infarction who underwent primary percutaneous coronary intervention were included. Within 48 h of intervention, 2-dimensional echocardiography was performed to assess LV volumes, LV ejection fraction (LVEF), wall motion score index, Left atrial dimension, E/E′ ratio, and severity of mitral regurgitation. Left Ventricular Dyssynchrony was determined using speckle-tracking radial strain analysis. At 6-month follow-up, LV volumes, LVEF, and severity of mitral regurgitation were reassessed. Results Patients showing LV remodeling at 6-month follow-up (20%) had comparable baseline characteristics to patients without LV remodeling (80%), except for higher peak troponin T levels (p Conclusions Left Ventricular Dyssynchrony immediately after acute myocardial infarction predicts LV remodeling at 6-month follow-up.

  • assessment of Left Ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
    Journal of the American College of Cardiology, 2006
    Co-Authors: Jos J.m. Westenberg, Martin J Schalij, Eduard R Holman, Ernst E Van Der Wall, Gabe B. Bleeker, Albert De Roos, Rob J Van Der Geest, Hildo J Lamb, J.h.c. Reiber
    Abstract:

    OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for Left Ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that intraVentricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study intraVentricular Dyssynchrony. RESULTS: Left Ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.

  • Tissue Doppler imaging to assess Left Ventricular Dyssynchrony and resynchronization therapy.
    European Journal of Echocardiography, 2005
    Co-Authors: Gabe B. Bleeker, Martin J Schalij, Ernst E Van Der Wall
    Abstract:

    We describe the use of tissue Doppler imaging to assess Left Ventricular Dyssynchrony and subsequent resynchronization in a patient with end-stage heart failure undergoing cardiac resynchronization therapy.

  • relationship between qrs duration and Left Ventricular Dyssynchrony in patients with end stage heart failure
    Journal of Cardiovascular Electrophysiology, 2004
    Co-Authors: B Gabe M D Bleeker, Martin J Schalij, G Sander M D Molhoek, Harriette F Verwey, Eduard R Holman, Eric Boersma, Paul Steendijk, Ernst E Van Der Wall
    Abstract:

    Introduction: Patients with end-stage heart failure and a wide QRS complex are considered candidates for cardiac resynchronization therapy (CRT). However, 20% to 30% of patients do not respond to CRT. Lack of Left Ventricular Dyssynchrony may explain the nonresponse. Accordingly, we evaluated the presence of Left Ventricular Dyssynchrony using tissue Doppler imaging (TDI) in 90 consecutive patients with heart failure. Methods and Results: Ninety patients with severe heart failure (Left Ventricular ejection fraction 150 ms). All patients underwent TDI to assess Left Ventricular Dyssynchrony. Extensive Left Ventricular Dyssynchrony was defined as an electromechanical delay on TDI between the septum and lateral wall, the so-called septal-to-lateral delay, of >60 ms. Severe Dyssynchrony was observed in 27% of patients with narrow QRS complex, 60% with intermediate QRS duration, and 70% with wide QRS complex. No relation existed between QRS duration and septal-to-lateral delay. Conclusion: From 30% to 40% of heart failure patients with QRS duration >120 ms do not exhibit Left Ventricular Dyssynchrony, which may explain the nonresponse to CRT. Alternatively, 27% of patients with heart failure and a narrow QRS complex show significant Left Ventricular Dyssynchrony and may be candidates for CRT. (J Cardiovasc Electrophysiol, Vol. 15, pp. 544-549, May 2004)

Eric Boersma - One of the best experts on this subject based on the ideXlab platform.

  • magnetic resonance imaging and response to cardiac resynchronization therapy relative merits of Left Ventricular Dyssynchrony and scar tissue
    European Heart Journal, 2009
    Co-Authors: Nina Ajmone Marsan, Eric Boersma, Jos J.m. Westenberg, Laurens F. Tops, Claudia Ypenburg, Rutger J Van Bommel, Stijntje D Roes, Victoria Delgado, Rob J Van Der Geest, Albert De Roos
    Abstract:

    Aim To assess the relative value of a novel measure of Left Ventricular (LV) Dyssynchrony derived from magnetic resonance imaging (MRI) and the extent of scar tissue for prediction of response to cardiac resynchronization therapy (CRT). Methods and results Thirty-five heart failure patients scheduled for CRT were included. Left Ventricular Dyssynchrony was defined as the standard deviation of 16 segment time-to-maximum radial wall thickness (SDt-16) obtained from a cine-set of short-axis slices. Delayed-enhanced MRI was performed for scar analysis. Echocardiography was used to determine response to CRT (reduction ≥15% in LV end-systolic volume 6 months after implantation). At follow-up, 21 patients (60%) were classified as responders. On MRI, SDt-16 was significantly higher in responders compared with non-responders (median 97 vs. 60 ms, P < 0.001), whereas the total extent of scar was larger in non-responders (median 35% vs. 3% in responders, P < 0.001). At the logistic regression analysis, SDt-16 was directly associated (OR = 6.3, 95% CI 3.1–9.9, P < 0.001) and the total extent of scar was inversely associated (OR = 0.52, 95% CI 0.43–0.87, P < 0.001) with response to CRT. Conclusion Magnetic resonance imaging offers the unique opportunity to assess LV Dyssynchrony and scar extent in a single session. Both these parameters are important predictors of echocardiographic response to CRT.

  • Left Ventricular Dyssynchrony acutely after myocardial infarction predicts Left Ventricular remodeling
    Journal of the American College of Cardiology, 2007
    Co-Authors: Sjoerd A Mollema, Eduard R Holman, Eric Boersma, Ernst E Van Der Wall, Gabe B. Bleeker, Su San Liem, Matthew S Suffoletto, Bas L Van Der Hoeven, Nico R Van De Veire, Martin J Schalij
    Abstract:

    Objectives We sought to identify predictors of Left Ventricular (LV) remodeling after acute myocardial infarction. Background Left Ventricular remodeling after myocardial infarction is associated with an adverse long-term prognosis. Early identification of patients prone to LV remodeling is needed to optimize therapeutic management. Methods A total of 178 consecutive patients presenting with acute myocardial infarction who underwent primary percutaneous coronary intervention were included. Within 48 h of intervention, 2-dimensional echocardiography was performed to assess LV volumes, LV ejection fraction (LVEF), wall motion score index, Left atrial dimension, E/E′ ratio, and severity of mitral regurgitation. Left Ventricular Dyssynchrony was determined using speckle-tracking radial strain analysis. At 6-month follow-up, LV volumes, LVEF, and severity of mitral regurgitation were reassessed. Results Patients showing LV remodeling at 6-month follow-up (20%) had comparable baseline characteristics to patients without LV remodeling (80%), except for higher peak troponin T levels (p Conclusions Left Ventricular Dyssynchrony immediately after acute myocardial infarction predicts LV remodeling at 6-month follow-up.

  • relationship between qrs duration and Left Ventricular Dyssynchrony in patients with end stage heart failure
    Journal of Cardiovascular Electrophysiology, 2004
    Co-Authors: B Gabe M D Bleeker, Martin J Schalij, G Sander M D Molhoek, Harriette F Verwey, Eduard R Holman, Eric Boersma, Paul Steendijk, Ernst E Van Der Wall
    Abstract:

    Introduction: Patients with end-stage heart failure and a wide QRS complex are considered candidates for cardiac resynchronization therapy (CRT). However, 20% to 30% of patients do not respond to CRT. Lack of Left Ventricular Dyssynchrony may explain the nonresponse. Accordingly, we evaluated the presence of Left Ventricular Dyssynchrony using tissue Doppler imaging (TDI) in 90 consecutive patients with heart failure. Methods and Results: Ninety patients with severe heart failure (Left Ventricular ejection fraction 150 ms). All patients underwent TDI to assess Left Ventricular Dyssynchrony. Extensive Left Ventricular Dyssynchrony was defined as an electromechanical delay on TDI between the septum and lateral wall, the so-called septal-to-lateral delay, of >60 ms. Severe Dyssynchrony was observed in 27% of patients with narrow QRS complex, 60% with intermediate QRS duration, and 70% with wide QRS complex. No relation existed between QRS duration and septal-to-lateral delay. Conclusion: From 30% to 40% of heart failure patients with QRS duration >120 ms do not exhibit Left Ventricular Dyssynchrony, which may explain the nonresponse to CRT. Alternatively, 27% of patients with heart failure and a narrow QRS complex show significant Left Ventricular Dyssynchrony and may be candidates for CRT. (J Cardiovasc Electrophysiol, Vol. 15, pp. 544-549, May 2004)

  • usefulness of myocardial tissue doppler echocardiography to evaluate Left Ventricular Dyssynchrony before and after biVentricular pacing in patients with idiopathic dilated cardiomyopathy
    American Journal of Cardiology, 2003
    Co-Authors: Sander G Molhoek, Martin J Schalij, Eric Boersma, Paul Steendijk, Lieselot Van Erven, P J Voogd, Soeresh Somer, Ernst E Van Der Wall
    Abstract:

    Tissue Doppler imaging allows assessment of Left Ventricular Dyssynchrony and resynchronization after biVentricular pacing.

Gabe B. Bleeker - One of the best experts on this subject based on the ideXlab platform.

  • Left Ventricular Dyssynchrony acutely after myocardial infarction predicts Left Ventricular remodeling
    Journal of the American College of Cardiology, 2007
    Co-Authors: Sjoerd A Mollema, Eduard R Holman, Eric Boersma, Ernst E Van Der Wall, Gabe B. Bleeker, Su San Liem, Matthew S Suffoletto, Bas L Van Der Hoeven, Nico R Van De Veire, Martin J Schalij
    Abstract:

    Objectives We sought to identify predictors of Left Ventricular (LV) remodeling after acute myocardial infarction. Background Left Ventricular remodeling after myocardial infarction is associated with an adverse long-term prognosis. Early identification of patients prone to LV remodeling is needed to optimize therapeutic management. Methods A total of 178 consecutive patients presenting with acute myocardial infarction who underwent primary percutaneous coronary intervention were included. Within 48 h of intervention, 2-dimensional echocardiography was performed to assess LV volumes, LV ejection fraction (LVEF), wall motion score index, Left atrial dimension, E/E′ ratio, and severity of mitral regurgitation. Left Ventricular Dyssynchrony was determined using speckle-tracking radial strain analysis. At 6-month follow-up, LV volumes, LVEF, and severity of mitral regurgitation were reassessed. Results Patients showing LV remodeling at 6-month follow-up (20%) had comparable baseline characteristics to patients without LV remodeling (80%), except for higher peak troponin T levels (p Conclusions Left Ventricular Dyssynchrony immediately after acute myocardial infarction predicts LV remodeling at 6-month follow-up.

  • assessment of Left Ventricular Dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy head to head comparison between tissue doppler imaging and velocity encoded magnetic resonance imaging
    Journal of the American College of Cardiology, 2006
    Co-Authors: Jos J.m. Westenberg, Martin J Schalij, Eduard R Holman, Ernst E Van Der Wall, Gabe B. Bleeker, Albert De Roos, Rob J Van Der Geest, Hildo J Lamb, J.h.c. Reiber
    Abstract:

    OBJECTIVES: This study sought to compare tissue Doppler imaging (TDI) with velocity-encoded (VE) magnetic resonance imaging (MRI) for Left Ventricular (LV) Dyssynchrony assessment. BACKGROUND: Cardiac resynchronization therapy (CRT) is proposed for patients with heart failure, depressed LV function, and a wide QRS complex. Selection is based mainly on electrocardiogram criteria, but recent data suggest that intraVentricular Dyssynchrony may be preferred for selection. An LV Dyssynchrony can adequately be assessed with TDI, but this has not been compared directly with other imaging modalities. A VE MRI potentially allows direct myocardial wall motion measurements similar to TDI. METHODS: Twenty patients with heart failure, systolic LV dysfunction, and a wide QRS complex were included, as well as 10 normal individuals with normal QRS duration and LV function. The TDI and VE MRI data were acquired to study intraVentricular Dyssynchrony. RESULTS: Left Ventricular Dyssynchrony was not observed in normal individuals (mean Dyssynchrony -2 +/- 15 ms on TDI; mean -5 +/- 17 ms on MRI, p = NS). In patients, mean LV Dyssynchrony was 55 +/- 37 ms on TDI; 49 +/- 38 ms on MRI (p = NS). Good correlation between both modalities was observed (linear regression TDI = 0.99 x MRI - 5, n = 30, r = 0.98, p < 0.01). The MRI showed a small, nonsignificant underestimation of 5 +/- 8 ms compared with TDI. Agreement between MRI and TDI for classification according to severity of LV Dyssynchrony (minimal, intermediate, and extensive) was excellent (kappa +/- SE = 0.96 +/- 0.07, p < 0.01) with 95% of patients classified identical. CONCLUSIONS: Both MRI and TDI yield comparable information on LV Dyssynchrony; MRI is useful in the selection of patients for CRT.

  • Tissue Doppler imaging to assess Left Ventricular Dyssynchrony and resynchronization therapy.
    European Journal of Echocardiography, 2005
    Co-Authors: Gabe B. Bleeker, Martin J Schalij, Ernst E Van Der Wall
    Abstract:

    We describe the use of tissue Doppler imaging to assess Left Ventricular Dyssynchrony and subsequent resynchronization in a patient with end-stage heart failure undergoing cardiac resynchronization therapy.

Erick Alexánderson-rosas - One of the best experts on this subject based on the ideXlab platform.

  • Left Ventricular Dyssynchrony and abnormalities in wall motion, assessed by gated-SPECT as ischemic auxiliary markers
    Journal of Nuclear Cardiology, 2018
    Co-Authors: Jorge Camilletti, Juan Erriest, Salvador Hernández-sandoval, Mónica Redolatti, Luis Cartasegna, Víctor Arregui, Gustavo Vigo, Nilda Espinola-zavaleta, Erick Alexánderson-rosas
    Abstract:

    Introduction Left Ventricular Dyssynchrony (LVD) quantified by gated myocardial perfusion studies (MPS), through phase analysis (PA), has shown controversial results in myocardial stunning. Objectives Assessment of LVD and regional wall motion abnormalities (RWMA) in normal and ischemic patients. Methods A cohort of 172 patients were studied. Summed Stress Score (SSS), Summed Resting Score (SRS), and Summed Difference Score (SDS) were evaluated. Group 1-patients with normal MPS (N = 133) and Group 2-patients with myocardial ischemia in the MPS (N = 39). LVD was evaluated through PA and RWM by visual analysis. Results SSS 0 vs 9.8 ± 3.9 P  = .0001; SDS 0 vs 9.8 ± 3.9 P  = .0001; SRS 0 vs 0 P  = NS, in G1 and G2. Significant differences were found in LVD between G1 and G2, bandwidth 36 ± 14 vs 63 ± 46 P  = .0001; standard deviation 16 ± 10 vs 26 ± 15 P  = .0001. In G1, 16% had LVD vs RWMA in 0%, P  = .0001 and in G2, 59% with LVD vs 33% with RWMA, P  = .03. Sensitivity for LVD 59% and for RWMA 33%, P  = .03 and specificity for LVD 83% and for RWMA 100%, P  = .0001. Conclusion Ischemic patients have LVD post-stress due to myocardial stunning. LVD measured by PA could be a useful tool to identify ischemia.

  • Left Ventricular Dyssynchrony and abnormalities in wall motion, assessed by gated-SPECT as ischemic auxiliary markers
    Journal of Nuclear Cardiology, 2018
    Co-Authors: Jorge Camilletti, Juan Erriest, Salvador Hernández-sandoval, Mónica Redolatti, Luis Cartasegna, Víctor Arregui, Gustavo Vigo, Nilda Espinola-zavaleta, Erick Alexánderson-rosas
    Abstract:

    INTRODUCTION: Left Ventricular Dyssynchrony (LVD) quantified by gated myocardial perfusion studies (MPS), through phase analysis (PA), has shown controversial results in myocardial stunning. OBJECTIVES: Assessment of LVD and regional wall motion abnormalities (RWMA) in normal and ischemic patients. METHODS: A cohort of 172 patients were studied. Summed Stress Score (SSS), Summed Resting Score (SRS), and Summed Difference Score (SDS) were evaluated. Group 1-patients with normal MPS (N = 133) and Group 2-patients with myocardial ischemia in the MPS (N = 39). LVD was evaluated through PA and RWM by visual analysis. RESULTS: SSS 0 vs 9.8 ± 3.9 P = .0001; SDS 0 vs 9.8 ± 3.9 P = .0001; SRS 0 vs 0 P = NS, in G1 and G2. Significant differences were found in LVD between G1 and G2, bandwidth 36 ± 14 vs 63 ± 46 P = .0001; standard deviation 16 ± 10 vs 26 ± 15 P = .0001. In G1, 16% had LVD vs RWMA in 0%, P = .0001 and in G2, 59% with LVD vs 33% with RWMA, P = .03. Sensitivity for LVD 59% and for RWMA 33%, P = .03 and specificity for LVD 83% and for RWMA 100%, P = .0001. CONCLUSION: Ischemic patients have LVD post-stress due to myocardial stunning. LVD measured by PA could be a useful tool to identify ischemia.