The Experts below are selected from a list of 159 Experts worldwide ranked by ideXlab platform
L Thomas - One of the best experts on this subject based on the ideXlab platform.
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surgical pearl dermoscopy of the free edge of the Nail to determine the level of Nail plate Pigmentation and the location of its probable origin in the proximal or distal Nail matrix
Journal of The American Academy of Dermatology, 2006Co-Authors: Ralph P Braun, Robert Baran, Jeanhilaire Saurat, L ThomasAbstract:N ail Pigmentation (melanonychia) is a common problem in dermatological practice. For the management of Nail Pigmentations, it is important to know the exact anatomic location of the pathologic feature (proximal or distal Nail matrix). This enables the surgeon to choose the correct biopsy site and the adequate surgical technique. For the patient this is important because biopsy of the proximal Nail matrix is much more likely to result in a permanent Nail dystrophy. On the other hand, a biopsy specimen up to 3 mm in size taken from the distal part of the Nail matrix usually does not affect Nail growth. It is currently possible to identify the origin of Nail Pigmentation by using Fontana-Masson staining of a Nail plate clipping specimen. This is the standard technique, which is relatively expensive and most important does not provide the answer immediately
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dermoscopic examination of Nail Pigmentation
Archives of Dermatology, 2002Co-Authors: Sandra Ronger, Anne Marie Viallard, Sandrine Touzet, Claire Ligeron, B Balme, Daniele Barrut, Cyrille Colin, L ThomasAbstract:Background: Diagnosis of longitudinal melanonychia is usually difficult, and neither a single clinical criterion nor a combination of symptoms currently can be used to clearly distinguish malignant from benign bandlike pig- mented Nail lesions. Biopsy is painful and often leaves definitive dystrophic scars. Objectives: To describe and evaluate dermoscopic pat- terns associated with longitudinal Nail Pigmentation. Patients and Methods: A total of 148 unselected con- secutive cases of longitudinal melanonychia were included over a period of 4 years (20 melanoma, 37 nevi, 16 drug- induced Nail Pigmentation, 45 Nail apparatus lentigo of vari- ous types, 8 ethnic-type Nail Pigmentation, and 22 subun- gual hemorrhages). All patients were recruited from the dermatology unit outpatient clinic of the Hotel Dieu de Lyon. All cases were photographed in vivo under oil im- mersion (dermoscopy). Patterns were recorded prior to fi- nal pathologic diagnosis. An independent biostatistics unit performed statistical evaluation using 7 semiologic patterns. Results: Melanoma cases were significantly associated with a brown coloration of the background and the pres- ence of irregular longitudinal lines (P=.001). Blood spots were mostly observed in subungual hemorrhages (P = .001); however, their presence could not rule out melanoma. Micro-Hutchinson sign was observed only in melanoma, but its rare occurrence did not allow any statistical evaluation of its specificity. Nail apparatus nevi were significantly associated with a brown coloration of the background and the presence of regular lines (P=.001). Nail apparatus lentigo, ethnic-type pigmen- tation, and drug-induced Pigmentation were signifi- cantly associated with homogeneous longitudinal thin gray lines and gray coloration of the background (P=.001). Microscopic longitudinal grooves were unspecific, oc- curred in several conditions, and were associated with any type of ungual discoloration. Conclusions: We believe that dermoscopic examina- tion of the Nail plate in cases of longitudinal melano- nychia provides useful information that could help cli- nicians to more accurately decide if a Nail apparatus biopsy should be performed; however, histopathologic diagno- sis remains the gold standard in doubtful cases. Arch Dermatol. 2002;138:1327-1333
Beth S. Ruben - One of the best experts on this subject based on the ideXlab platform.
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histological analysis of the Nail plate in the diagnosis of melanonychia and other Nail Pigmentation
2017Co-Authors: Beth S. RubenAbstract:Melanocytic activation is a common cause of Pigmentation of the Nail plate and consists of melanin production without a proliferation of melanocytes. Melanocytic proliferations (lentigo, nevi, and melanoma) often produce a solitary longitudinal pigmented band. Other causes of Nail plate Pigmentation: pigmented squamous cell carcinoma, pigmented onychomatricoma, onychocytic matricoma, pigmented onychomycosis, and Nail plate hemorrhage. Nail clipping can serve as a less invasive screening procedure for identifying the cause of Nail plate discoloration. Fontana–Masson staining is useful in identifying melanin. Benzidine stain can be used to identify hemoglobin.
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consenso sobre dermatoscopia da placa ungueal em melanoniquias consensus on melanonychia Nail plate dermoscopy
2013Co-Authors: Nilton Di Chiacchio, Pier Alessandro Fanti, Bianca Maria Piraccini, Débora Cadore De Farias, Sergio Henrique Hirata, Bertrand Richert, Martin Zaiac, R. Daniel, Josette André, Beth S. RubenAbstract:Resumo: Este consenso, com foco em melanoniquia e dermatoscopia da lâmina ungueal, se destina a orientar os medicos que trabalham com melanoniquia e auxiliar no manejo destes pacientes. O grupo internacional de estu- dos sobre melanoniquia foi fundada em 2007 e tem agora 30 membros, incluindo dermatologistas e dermatopa- tologistas com conhecimento especializado em unhas. A necessidade de definicoes comuns de dermatoscopia da lâmina ungueal foi abordada durante a segunda reuniao deste grupo, realizada em fevereiro de 2008. Antes desta reuniao e ate a presente, nao existem orientacoes com base em evidencias sobre a utilizacao de dermatoscopia da placa ungueal. Palavras-chave: Dermoscopia; Doencas da unha; Melanoma; Unhas Abstract: This statement, focused on melanonychia and Nail plate dermoscopy, is intended to guide medical pro- fessionals working with melanonychia and to assist choosing appropriate management for melanonychia patients. The International Study Group on Melanonychia was founded in 2007 and currently has 30 members, including Nail experts and dermatopathologists with special expertise in Nails. The need for common definitions of Nail plate dermoscopy was addressed during the Second Meeting of this Group held in February 2008. Prior to this meeting and to date (2010) there have been no evidence-based guidelines on the use of dermoscopy in the management of Nail Pigmentation.
Bianca Maria Piraccini - One of the best experts on this subject based on the ideXlab platform.
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WHEN THE Nail APPERANCE PLAYS TRICKS: A CASE OF LONGITUDINAL MELANONYCHIA
2018Co-Authors: Starace Michela, Bianca Maria Piraccini, Nicolò Brandi, Aurora AlessandriniAbstract:A paediatric Nail consultation is often required to reduce parents’ concerns regarding their child’s abnormal Nail appearance. Nail Pigmentation in children is a dermatological challenge because guidelines are not standardised, causing many doubts for dermatologists. In general, the majority of cases of melanonychia are benign in children and Nail melanoma cases are very rare. However, alarming clinical and dermoscopic features can be observed, requiring Nail surgery to confrm a diagnosis. Here, we present a case of longitudinal melanonychia in a teenager with atypical signs and a good prognosis
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Tips for Diagnosis and Treatment of Nail Pigmentation with Practical Algorithm
Dermatologic Clinics, 2015Co-Authors: Bianca Maria Piraccini, Emi Dika, Pier Alessandro FantiAbstract:The observation of a black-brown Pigmentation of the Nail is often alarming for the patient and for the clinician, as they are aware that it can be a possible clinical manifestation of melanoma of the Nail apparatus. Luckily, however, Nail melanoma is a much less frequent cause of brown-black Nail color than other melanocytic and nonmelanocytic Pigmentations, which include subungual hematoma, exogenous Pigmentations, and melanonychia due to benign conditions. A correct clinical history and careful examination help the clinician to distinguish the different conditions and to decide the correct management of melanonychia both in children and in adults.
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consenso sobre dermatoscopia da placa ungueal em melanoniquias consensus on melanonychia Nail plate dermoscopy
2013Co-Authors: Nilton Di Chiacchio, Pier Alessandro Fanti, Bianca Maria Piraccini, Débora Cadore De Farias, Sergio Henrique Hirata, Bertrand Richert, Martin Zaiac, R. Daniel, Josette André, Beth S. RubenAbstract:Resumo: Este consenso, com foco em melanoniquia e dermatoscopia da lâmina ungueal, se destina a orientar os medicos que trabalham com melanoniquia e auxiliar no manejo destes pacientes. O grupo internacional de estu- dos sobre melanoniquia foi fundada em 2007 e tem agora 30 membros, incluindo dermatologistas e dermatopa- tologistas com conhecimento especializado em unhas. A necessidade de definicoes comuns de dermatoscopia da lâmina ungueal foi abordada durante a segunda reuniao deste grupo, realizada em fevereiro de 2008. Antes desta reuniao e ate a presente, nao existem orientacoes com base em evidencias sobre a utilizacao de dermatoscopia da placa ungueal. Palavras-chave: Dermoscopia; Doencas da unha; Melanoma; Unhas Abstract: This statement, focused on melanonychia and Nail plate dermoscopy, is intended to guide medical pro- fessionals working with melanonychia and to assist choosing appropriate management for melanonychia patients. The International Study Group on Melanonychia was founded in 2007 and currently has 30 members, including Nail experts and dermatopathologists with special expertise in Nails. The need for common definitions of Nail plate dermoscopy was addressed during the Second Meeting of this Group held in February 2008. Prior to this meeting and to date (2010) there have been no evidence-based guidelines on the use of dermoscopy in the management of Nail Pigmentation.
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Taxane-induced Nail changes: incidence, clinical presentation and outcome
Annals of oncology : official journal of the European Society for Medical Oncology, 2003Co-Authors: Alessandro Marco Minisini, Bianca Maria Piraccini, Antonella Tosti, Alberto Sobrero, Mauro Mansutti, Cosimo Sacco, Fabio PuglisiAbstract:The clinical characteristics of Nail changes in seven patients receiving taxane-containing chemotherapy are described. They include Nail Pigmentation, subungual hematoma, Beau's lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0% to 44%) is reviewed from a Medline search of the literature.
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© 2003 European Society for Medical Oncology Taxane-induced Nail changes: incidence, clinical presentation
2002Co-Authors: Alessandro Marco Minisini, Bianca Maria Piraccini, Antonella Tosti, Alberto Sobrero, Mauro Mansutti, Cosimo Sacco, Fabio PuglisiAbstract:The clinical characteristics of Nail changes in seven patients receiving taxane-containing chemotherapy are described. They include Nail Pigmentation, subungual hematoma, Beau’s lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0 % to 44%) is reviewed from a Medline search of the literature
Feroze Kaliyadan - One of the best experts on this subject based on the ideXlab platform.
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Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy [version 1; referees: 2 approved]
F1000 Research Ltd, 2018Co-Authors: Sidharth Sonthalia, Sangeeta Varma, Abhijeet Kumar Jha, Deepak Jakhar, Feroze KaliyadanAbstract:Dermoscopy, a non-invasive technique for cutaneous diagnosis is being increasingly studied in various disorders of the skin, Nails and scalp. However, it has been under-utilized for the diagnosis and characterization of mucosal disorders. The dermoscopic characterization of cutaneous lichen planus and its variants has been well documented with Wickham’s striae constituting the hallmark of the condition. However, the dermoscopic features of oral lichen planus with hand-held or videodermoscopy remain to be elucidated. We present the case of a young adult man who presented with asymptomatic white lacy lesions over a bluish-black background over the tongue, patchy hyperPigmentation of the buccal mucosa and gingivae, and longitudinal melanonychia involving some Nails. History of intake of any drugs preceding the lesions, smoking, chewing of betel nut and dental implants was negative. Family history was non-contributory. There were no cutaneous lesions suggestive of lichen planus. Mucoscopy (dermoscopy of the mucosa, oral in this case) and onychoscopy were done followed by biopsy from the tongue that confirmed the diagnosis of lichen planus. Oral mucoscopy of the tongue revealed a tri-colored pattern with structureless veil-like grey-white areas (modified Wickham’s striae), well-demarcated red glossy erosions, and violaceous-to-brown clods. Additionally, vascular pattern of dotted and linear to curved vessels along the borders of leukoplakia-like areas and erosions were observed. Onychoscopy confirmed lichen planus-associated melanonychia. Dermoscopy also proved useful in conveniently ruling out other disorders typified by mucosal and Nail Pigmentation such as Laugier Hunziker syndrome and drug-induced changes. Although direct oral microscopy has been used in defining features of oral lichen planus, to the best of our knowledge this case is the first report on mucoscopy or dermoscopy of oral lichen planu
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Case Report: Dermoscopic features of oral lichen planus - the evolution of mucoscopy [version 2; referees: 2 approved]
F1000 Research Ltd, 2018Co-Authors: Sidharth Sonthalia, Sangeeta Varma, Abhijeet Kumar Jha, Deepak Jakhar, Feroze KaliyadanAbstract:Dermoscopy, a non-invasive technique for cutaneous diagnosis is being increasingly studied in various disorders of the skin, Nails and scalp. However, it has been under-utilized for the diagnosis and characterization of mucosal disorders. The dermoscopic characterization of cutaneous lichen planus and its variants has been well documented with Wickham’s striae constituting the hallmark of the condition. However, the dermoscopic features of oral lichen planus with hand-held or videodermoscopy remain to be elucidated. We present the case of a young adult man who presented with asymptomatic white lacy lesions over a bluish-black background over the tongue, patchy hyperPigmentation of the buccal mucosae and gingivae, and longitudinal melanonychia involving some Nails. History of intake of any drugs preceding the lesions, smoking, chewing of betel nut and dental implants was negative. Family history was non-contributory. There were no cutaneous lesions suggestive of lichen planus. Mucoscopy (dermoscopy of the mucosa, oral in this case) and onychoscopy were done followed by biopsy from the tongue that confirmed the diagnosis of lichen planus. Oral mucoscopy of the tongue revealed a tri-colored pattern with structureless veil-like grey-white areas (modified Wickham’s striae), well-demarcated red glossy erosions, and violaceous-to-brown clods. Additionally, vascular pattern of dotted and linear to curved vessels along the borders of leukoplakia-like areas and erosions were observed. Onychoscopy confirmed lichen planus-associated melanonychia. Dermoscopy also proved useful in conveniently ruling out other disorders typified by mucosal and Nail Pigmentation such as Laugier Hunziker syndrome and drug-induced changes. Although direct oral microscopy has been used in defining features of oral lichen planus, to the best of our knowledge this case is the first report on mucoscopy or dermoscopy of oral lichen planu
Jeho Mun - One of the best experts on this subject based on the ideXlab platform.
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dermoscopic patterns of fungal melanonychia a comparative study with other causes of melanonychia
Journal of The American Academy of Dermatology, 2017Co-Authors: Jungyoon Ohn, Yun Seon Choe, Jin Park, Jeho MunAbstract:Background Diagnosing fungal melanonychia (FM) is often difficult because it mimics melanonychia caused by other factors. Dermoscopy is helpful in the setting of Nail Pigmentation. However, the diagnostic characteristics of FM on dermoscopy are not fully elucidated. Objective We sought to determine the dermoscopic characteristics of FM. Methods We evaluated the dermoscopic patterns of FM diagnosed at 2 university hospitals from January 2010 to February 2016. We included Nail matrix melanocytic activation, Nail matrix nevi, and Nail unit malignant melanomas as control groups for comparison. Results In all, 18 FM, 24 melanocytic activation of the Nail matrix, 27 Nail matrix nevi, and 11 malignant melanoma cases were analyzed. Statistical analysis revealed that yellow color, multicolor pattern, nonlongitudinal homogenous pattern, reverse triangular pattern, subungual keratosis, white or yellow streaks, and scales on the Nail were more frequent in FM. However, gray color, longitudinal pattern, and pseudo-Hutchinson sign were less frequent in FM than in controls. Limitations This was a retrospective study from 2 university hospitals, with a small sample size. Conclusion The results revealed distinctive dermoscopic patterns for FM. Therefore, dermoscopy can be a useful ancillary tool for diagnosing FM.
