The Experts below are selected from a list of 228 Experts worldwide ranked by ideXlab platform
Elizabeth P. Ryan - One of the best experts on this subject based on the ideXlab platform.
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Navy beans impact the stool metabolome and metabolic pathways for colon health in cancer survivors
Nutrients, 2018Co-Authors: Bridget A. Baxter, Renee C. Oppel, Elizabeth P. RyanAbstract:Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States and emerging evidence supports that increased consumption of legumes, such as Navy beans, can reduce risk. Navy bean consumption was previously shown to modulate host and microbiome metabolism, and this investigation was performed to assess the impact on the human stool metabolome, which includes the presence of Navy bean metabolites. This 4-week, randomized-controlled trial with overweight and obese CRC survivors involved consumption of 1 meal and 1 snack daily. The intervention contained 35 g of cooked Navy bean or macronutrient matched meals and snacks with 0 g of Navy beans for the control group (n = 18). There were 30 statistically significant metabolite differences in the stool of participants that consumed Navy bean at day 28 compared to the participants’ baseline (p ≤ 0.05) and 26 significantly different metabolites when compared to the control group. Of the 560 total metabolites identified from the cooked Navy beans, there were 237 possible Navy bean-derived metabolites that were identified in the stool of participants consuming Navy beans, such as N-methylpipecolate, 2-aminoadipate, piperidine, and vanillate. The microbial metabolism of amino acids and fatty acids were also identified in stool after 4 weeks of Navy bean intake including cadaverine, hydantoin-5 propionic acid, 4-hydroxyphenylacetate, and caprylate. The stool relative abundance of ophthalmate increased 5.25-fold for Navy bean consumers that can indicate glutathione regulation, and involving cancer control mechanisms such as detoxification of xenobiotics, antioxidant defense, proliferation, and apoptosis. Metabolic pathways involving lysine, and phytochemicals were also modulated by Navy bean intake in CRC survivors. These metabolites and metabolic pathways represent an acute response to increased Navy bean intake, which merit further investigation for improving colonic health after long-term consumption.
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Navy Beans Impact the Stool Metabolome and Metabolic Pathways for Colon Health in Cancer Survivors
MDPI AG, 2018Co-Authors: Bridget A. Baxter, Renee C. Oppel, Elizabeth P. RyanAbstract:Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States and emerging evidence supports that increased consumption of legumes, such as Navy beans, can reduce risk. Navy bean consumption was previously shown to modulate host and microbiome metabolism, and this investigation was performed to assess the impact on the human stool metabolome, which includes the presence of Navy bean metabolites. This 4-week, randomized-controlled trial with overweight and obese CRC survivors involved consumption of 1 meal and 1 snack daily. The intervention contained 35 g of cooked Navy bean or macronutrient matched meals and snacks with 0 g of Navy beans for the control group (n = 18). There were 30 statistically significant metabolite differences in the stool of participants that consumed Navy bean at day 28 compared to the participants’ baseline (p ≤ 0.05) and 26 significantly different metabolites when compared to the control group. Of the 560 total metabolites identified from the cooked Navy beans, there were 237 possible Navy bean-derived metabolites that were identified in the stool of participants consuming Navy beans, such as N-methylpipecolate, 2-aminoadipate, piperidine, and vanillate. The microbial metabolism of amino acids and fatty acids were also identified in stool after 4 weeks of Navy bean intake including cadaverine, hydantoin-5 propionic acid, 4-hydroxyphenylacetate, and caprylate. The stool relative abundance of ophthalmate increased 5.25-fold for Navy bean consumers that can indicate glutathione regulation, and involving cancer control mechanisms such as detoxification of xenobiotics, antioxidant defense, proliferation, and apoptosis. Metabolic pathways involving lysine, and phytochemicals were also modulated by Navy bean intake in CRC survivors. These metabolites and metabolic pathways represent an acute response to increased Navy bean intake, which merit further investigation for improving colonic health after long-term consumption
Ian Speller - One of the best experts on this subject based on the ideXlab platform.
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Small Navies: Strategy and Policy for Small Navies in War and Peace
2014Co-Authors: Michael Mulqueen, Deborah Sanders, Ian SpellerAbstract:Preface, Michael Mulqueen, Deborah Sanders and Ian Speller Introduction, Ian Speller, Deborah Sanders and Michael Mulqueen The ranking of smaller navies revisited, Eric Grove Are small navies different?, Geoffrey Till Small navies in perspective: deconstructing the hierarchy of naval forces, Basil Germond Transforming small navies by systematic innovation: a framework for productivity, efficiency and effectiveness, Michael Mulqueen and Terry Warburton Adaptative dynamic capabilities and innovation: the key for small navies protecting national interests at and from the sea, Mark Mellett Small navies in Asia: the strategic rationale for growth, Michael McDevitt The Republic of Korea Navy - a 'big' small Navy, Ian Bowers 'Best little Navy in Southeast Asia': the case of the Republic of Singapore Navy, Swee Lean Collin Koh Small navies and border and immigration control: Frontex operations in the Mediterranean, Giampiero Giacomello and Chiara Ruffa Small navies in the Black Sea: a case study of Romania's maritime power, Deborah Sanders A small Navy in a changing world: the case of the Royal Swedish Navy, Niklas Granholm The strategic value of small navies: the strange case of the Confederate Navy, Christopher Tuck Learning to be small: the experience of the British Pacific Fleet, 1944-45, Jon Robb-Webb Appendix Bibliography Index.
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The Royal Navy and Maritime Power in the Twentieth Century
2004Co-Authors: Ian SpellerAbstract:Foreword Admiral Sir Julian Oswald Introduction Ian Speller Chapter 1. The Transition to War: The hunt for the Goeben and Breslau, 1914 Andrew Gordon Chapter 2. Sea Control in Narrow Waters: The battles of Taranto and Matapan Jon Robb-Webb Chapter 3. Sea Denial, Interdiction and Diplomacy: The Royal Navy and the Role of Malta, 1939-43 Greg Kennedy Chapter 4. Air Power and Evacuations: Crete, 1942 Stephen Prince Chapter 5. Amphibious Operations: The Royal Navy and the Italian campaign, 1943-1945 Christopher Tuck Chapter 6. Complex Crises: The Royal Navy and the Undeclared War with Vichy France, 1940-1942 Stuart Griffin Chapter 7. Quarantine Operations: The Royal Navy and the Palestine Patrol Geoffrey Till Chapter 8. Maritime Jurisdiction and the Law of the Sea Stuart Thomson Chapter 9. Naval Diplomacy: Operation Vantage, 1961 Ian Speller Chapter 10. Operations in a War Zone: The Royal Navy in the Persian Gulf in the 1980s Warren Chin Chapter 11. Peacekeeping, Peace Support and Peace Enforcement: The Royal Navy in the 1990s Andrew Dorman
Bridget A. Baxter - One of the best experts on this subject based on the ideXlab platform.
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Navy beans impact the stool metabolome and metabolic pathways for colon health in cancer survivors
Nutrients, 2018Co-Authors: Bridget A. Baxter, Renee C. Oppel, Elizabeth P. RyanAbstract:Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States and emerging evidence supports that increased consumption of legumes, such as Navy beans, can reduce risk. Navy bean consumption was previously shown to modulate host and microbiome metabolism, and this investigation was performed to assess the impact on the human stool metabolome, which includes the presence of Navy bean metabolites. This 4-week, randomized-controlled trial with overweight and obese CRC survivors involved consumption of 1 meal and 1 snack daily. The intervention contained 35 g of cooked Navy bean or macronutrient matched meals and snacks with 0 g of Navy beans for the control group (n = 18). There were 30 statistically significant metabolite differences in the stool of participants that consumed Navy bean at day 28 compared to the participants’ baseline (p ≤ 0.05) and 26 significantly different metabolites when compared to the control group. Of the 560 total metabolites identified from the cooked Navy beans, there were 237 possible Navy bean-derived metabolites that were identified in the stool of participants consuming Navy beans, such as N-methylpipecolate, 2-aminoadipate, piperidine, and vanillate. The microbial metabolism of amino acids and fatty acids were also identified in stool after 4 weeks of Navy bean intake including cadaverine, hydantoin-5 propionic acid, 4-hydroxyphenylacetate, and caprylate. The stool relative abundance of ophthalmate increased 5.25-fold for Navy bean consumers that can indicate glutathione regulation, and involving cancer control mechanisms such as detoxification of xenobiotics, antioxidant defense, proliferation, and apoptosis. Metabolic pathways involving lysine, and phytochemicals were also modulated by Navy bean intake in CRC survivors. These metabolites and metabolic pathways represent an acute response to increased Navy bean intake, which merit further investigation for improving colonic health after long-term consumption.
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Navy Beans Impact the Stool Metabolome and Metabolic Pathways for Colon Health in Cancer Survivors
MDPI AG, 2018Co-Authors: Bridget A. Baxter, Renee C. Oppel, Elizabeth P. RyanAbstract:Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States and emerging evidence supports that increased consumption of legumes, such as Navy beans, can reduce risk. Navy bean consumption was previously shown to modulate host and microbiome metabolism, and this investigation was performed to assess the impact on the human stool metabolome, which includes the presence of Navy bean metabolites. This 4-week, randomized-controlled trial with overweight and obese CRC survivors involved consumption of 1 meal and 1 snack daily. The intervention contained 35 g of cooked Navy bean or macronutrient matched meals and snacks with 0 g of Navy beans for the control group (n = 18). There were 30 statistically significant metabolite differences in the stool of participants that consumed Navy bean at day 28 compared to the participants’ baseline (p ≤ 0.05) and 26 significantly different metabolites when compared to the control group. Of the 560 total metabolites identified from the cooked Navy beans, there were 237 possible Navy bean-derived metabolites that were identified in the stool of participants consuming Navy beans, such as N-methylpipecolate, 2-aminoadipate, piperidine, and vanillate. The microbial metabolism of amino acids and fatty acids were also identified in stool after 4 weeks of Navy bean intake including cadaverine, hydantoin-5 propionic acid, 4-hydroxyphenylacetate, and caprylate. The stool relative abundance of ophthalmate increased 5.25-fold for Navy bean consumers that can indicate glutathione regulation, and involving cancer control mechanisms such as detoxification of xenobiotics, antioxidant defense, proliferation, and apoptosis. Metabolic pathways involving lysine, and phytochemicals were also modulated by Navy bean intake in CRC survivors. These metabolites and metabolic pathways represent an acute response to increased Navy bean intake, which merit further investigation for improving colonic health after long-term consumption
D. Michael Strong - One of the best experts on this subject based on the ideXlab platform.
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The US Navy Tissue Bank: 50 Years on the Cutting Edge
Cell and Tissue Banking, 2000Co-Authors: D. Michael StrongAbstract:The US Navy Tissue Bank was established in 1949 by Dr. George Hyatt, an orthopaedic surgeon at the Naval Medical Center in Bethesda, Maryland. The Navy program was the first of its kind in the world and established many of the standards that are followed today. During the 1950s, the identification of appropriate donor criteria for tissue donation, the development of procurement and processing methods, the establishment of a graph registry and documentation and the clinical evaluation of a variety of tissues were pioneered at this facility. Cryopreservation, freeze-drying, irradiation sterilization of tissue, as well as immunological principles of tissue transplantation, were developed during the 50 years of research and development by Navy scientists. Organ preservation, cadaveric bone marrow recovery and immunosuppressive protocols were also developed at the Navy Tissue Bank. The Navy was also instrumental in the establishment of the National Marrow Donor Program and the American Association of Tissue Banks in the US. Although the Navy Tissue Bank has ceased activity after 50 years of excellence, it should be recognized as the first standard setter for the world community of tissue banks.
James O. L’esperance - One of the best experts on this subject based on the ideXlab platform.
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A 10-Year Retrospective Review of Nephrolithiasis in the Navy and Navy Pilots
The Journal of urology, 2017Co-Authors: James H. Masterson, Christopher J. Phillips, Nancy F. Crum-cianflone, Robert J. Krause, Roger L. Sur, James O. L’esperanceAbstract:Purpose: Little is known about the incidence of nephrolithiasis in the United States Navy. Navy pilots must be kidney stone-free and are often referred for treatment of small asymptomatic stones. The primary objectives of this study were to determine the incidence of nephrolithiasis and computerized tomography, proportion undergoing treatment and incidence of stone related mishaps in Navy pilots compared with other Navy personnel.Materials and Methods: We retrospectively studied the records of all Navy service members from 2002 to 2011 for nephrolithiasis based on ICD-9 stone codes to determine the mentioned rates. We also reviewed NSC (Naval Safety Center) data for a history of accidents associated with nephrolithiasis. Rates of disease were calculated using person-years of followup and inferential statistics were done using univariable and multivariable analyses.Results: We evaluated 667,840 Navy personnel with a total of 3,238,331 person-years of followup. The annual incidence of nephrolithiasis was 24...
