Pseudobulbar Palsy

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J Sanssabrafen - One of the best experts on this subject based on the ideXlab platform.

  • acute Pseudobulbar Palsy as the initial presentation of intravascular lymphomatosis
    European Journal of Internal Medicine, 2004
    Co-Authors: Adria Arboix, Imgard Costa, Carles Besses, J Sanssabrafen
    Abstract:

    Abstract We describe the case of a 76-year-old male patient who developed acute manifestations of Pseudobulbar Palsy without a history of stroke or vascular risk factors as the first manifestation of intravascular lymphomatosis. Neurological symptoms of acute Pseudobulbar Palsy appeared on the second postoperative day after transurethral prostatectomy for the treatment of prostatic hypertrophy. Intravascular lymphomatosis was diagnosed from microscopic findings and immunohistochemical staining of the surgical specimen. Chemotherapy was started, but the patient died due to sepsis secondary to bone marrow aplasia. Intravascular lymphomatosis should be considered a rare potential cause of acute Pseudobulbar Palsy.

Andre Palmini - One of the best experts on this subject based on the ideXlab platform.

  • Bilateral perisylvian ulegyria: An under-recognized, surgically remediable epileptic syndrome
    Epilepsia, 2013
    Co-Authors: Lucas Porcello Schilling, Renata R. Kieling, Tharick A. Pascoal, Eliseu Paglioli, Pedro Rosa Neto, Jaderson Costa Da Costa, Andre Palmini
    Abstract:

    Summary Purpose Interest in the association of epilepsy and Pseudobulbar Palsy was rekindled since the identification through magnetic resonance imaging (MRI) of bilateral perisylvian polymicrogyria (PMG). Seizures are often intractable, but resective epilepsy surgery has not been recommended. However, a similar clinical picture can be encountered in patients with bilateral perisylvian destructive lesions, which fit the description of ulegyria (ULG). We report a series of patients with epilepsy and Pseudobulbar Palsy due to bilateral perisylvian ULG (BP-ULG), show that hippocampal sclerosis (HS) is often associated and highlight the fact that in this entity, unlike in malformative bilateral perisylvian PMG, seizures may be surgically treated. Methods The motor, cognitive, epileptologic, and imaging features of 12 patients with perisylvian ULG followed at three institutions are described. For patients with refractory seizures, we detail extracranial and intracranial electrographic recordings, surgical strategies, histopathologic analyses of the resected tissue, and outcome of surgical treatment. Descriptive statistics were used for quantitative and categorical variables. Student's t-test was used to compare means, and a p 

  • bilateral perisylvian ulegyria clinicopathological study of patients presenting with Pseudobulbar Palsy and epilepsy
    Neuropathology, 2006
    Co-Authors: Shin Jung, Andre Palmini
    Abstract:

    Structural abnormalities related with Pseudobulbar Palsy have been gaining attention because of their characteristic symptoms and unique pathogenesis. We present five cases of bilateral perisylvian ulegyria (BPU) presenting epilepsy and Pseudobulbar Palsy with pathogenesis different from previously reported syndromes. All patients showed medically intractable seizures, complex partial seizures with secondary generalization and clinical symptoms of Pseudobulbar Palsy, including dysarthria, limitation of tongue movement and drooling. MRI revealed BPU in all patients, and BPU associated with hippocampal sclerosis in four patients. Intracranial EEG recording with subdural grip and stripe was helpful for localizing the area of ictal generation. Resective surgeries, including the temporal lobe, central area and parietal lobe, were performed depending on the localizing information. The surgical outcome was favorable after 9.8 years of follow-up. Characteristic features of ulegyria were confirmed on pathological examination. Ulegyria is considered to be another important perinatal or postnatal structural abnormality which can explain the etiological heterogeneity for Pseudobulbar Palsy, which results from bilateral perisylvian lesions. Awareness of this disorder can provide a useful strategy for evaluation and treatment which differs from that in perisylvian polymicrogyria.

Adria Arboix - One of the best experts on this subject based on the ideXlab platform.

  • acute Pseudobulbar Palsy as the initial presentation of intravascular lymphomatosis
    European Journal of Internal Medicine, 2004
    Co-Authors: Adria Arboix, Imgard Costa, Carles Besses, J Sanssabrafen
    Abstract:

    Abstract We describe the case of a 76-year-old male patient who developed acute manifestations of Pseudobulbar Palsy without a history of stroke or vascular risk factors as the first manifestation of intravascular lymphomatosis. Neurological symptoms of acute Pseudobulbar Palsy appeared on the second postoperative day after transurethral prostatectomy for the treatment of prostatic hypertrophy. Intravascular lymphomatosis was diagnosed from microscopic findings and immunohistochemical staining of the surgical specimen. Chemotherapy was started, but the patient died due to sepsis secondary to bone marrow aplasia. Intravascular lymphomatosis should be considered a rare potential cause of acute Pseudobulbar Palsy.

Carles Besses - One of the best experts on this subject based on the ideXlab platform.

  • acute Pseudobulbar Palsy as the initial presentation of intravascular lymphomatosis
    European Journal of Internal Medicine, 2004
    Co-Authors: Adria Arboix, Imgard Costa, Carles Besses, J Sanssabrafen
    Abstract:

    Abstract We describe the case of a 76-year-old male patient who developed acute manifestations of Pseudobulbar Palsy without a history of stroke or vascular risk factors as the first manifestation of intravascular lymphomatosis. Neurological symptoms of acute Pseudobulbar Palsy appeared on the second postoperative day after transurethral prostatectomy for the treatment of prostatic hypertrophy. Intravascular lymphomatosis was diagnosed from microscopic findings and immunohistochemical staining of the surgical specimen. Chemotherapy was started, but the patient died due to sepsis secondary to bone marrow aplasia. Intravascular lymphomatosis should be considered a rare potential cause of acute Pseudobulbar Palsy.

  • brief report acute Pseudobulbar Palsy as the initial presentation of intravascular lymphomatosis
    2004
    Co-Authors: Imgard Costa, Carles Besses
    Abstract:

    We describe the case of a 76-year-old male patient who developed acute manifestations of Pseudobulbar Palsy without a history of stroke or vascular risk factors as the first manifestation of intravascular lymphomatosis. Neurological symptoms of acute Pseudobulbar Palsy appeared on the second postoperative day after transurethral prostatectomy for the treatment of prostatic hypertrophy. Intravascular lymphomatosis was diagnosed from microscopic findings and immunohistochemical staining of the surgical specimen. Chemotherapy was started, but the patient died due to sepsis secondary to bone marrow aplasia. Intravascular lymphomatosis should be considered a rare potential cause of acute Pseudobulbar Palsy. D 2004 Elsevier B.V. All rights reserved.

W U Qingming - One of the best experts on this subject based on the ideXlab platform.