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Preben Bjerregaard - One of the best experts on this subject based on the ideXlab platform.
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oral Sodium Phosphate versus sulfate free polyethylene glycol electrolyte lavage solution in outpatient preparation for colonoscopy a prospective comparison
Gastrointestinal Endoscopy, 1996Co-Authors: Wendell K Clarkston, Tony N Tsen, David F Dies, Lynn C Schratz, Surender K. Vaswani, Preben BjerregaardAbstract:Abstract Background: Biochemical abnormalities induced by oral Sodium Phosphate and the risk of cardiac arrhythmias as potential sequelae have yet to be investigated. Methods: We studied 98 outpatients scheduled to undergo diagnostic colonoscopy and prospectively randomized them to receive oral Sodium Phosphate or sulfate-free polyethylene glycol electrolyte lavage solution (SF-PEG-ELS) as recommended by the manufacturers. Results: Forty-nine patients received Sodium Phosphate and 49 received SF-PEG-ELS. There was no significant difference in tolerance or quality of preparation as judged by blinded endoscopists. Significant changes in serum Sodium, potassium, chloride, calcium, ionized calcium, and inorganic phosphorus levels were noted following Sodium Phosphate preparation when compared to values before preparation. A significantly greater number of patients who received Sodium Phosphate preparation had serum potassium and ionized calcium levels that fell into the abnormal range. Ambulatory electrocardiogram monitors placed 24 hours before the preparation and removed after colonoscopy showed no increase in ventricular premature contractions or other serious arrhythmias in either group during preparation or colonoscopy. Conclusions: (1) Sodium Phosphate and SF-PEG-ELS are equally well tolerated and effective in preparation for outpatient colonoscopy, and (2) Sodium Phosphate preparation at the recommended dose causes significant alterations in serum Sodium, potassium, chloride, calcium, ionized calcium, and phosphorus levels. (Gastrointest Endosc 1996;43:42-8.)
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oral Sodium Phosphate versus sulfate free polyethylene glycol electrolyte lavage solution in outpatient preparation for colonoscopy a prospective comparison
Gastrointestinal Endoscopy, 1996Co-Authors: Wendell K Clarkston, Tony N Tsen, David F Dies, Lynn C Schratz, Surender K. Vaswani, Preben BjerregaardAbstract:Abstract Background: Biochemical abnormalities induced by oral Sodium Phosphate and the risk of cardiac arrhythmias as potential sequelae have yet to be investigated. Methods: We studied 98 outpatients scheduled to undergo diagnostic colonoscopy and prospectively randomized them to receive oral Sodium Phosphate or sulfate-free polyethylene glycol electrolyte lavage solution (SF-PEG-ELS) as recommended by the manufacturers. Results: Forty-nine patients received Sodium Phosphate and 49 received SF-PEG-ELS. There was no significant difference in tolerance or quality of preparation as judged by blinded endoscopists. Significant changes in serum Sodium, potassium, chloride, calcium, ionized calcium, and inorganic phosphorus levels were noted following Sodium Phosphate preparation when compared to values before preparation. A significantly greater number of patients who received Sodium Phosphate preparation had serum potassium and ionized calcium levels that fell into the abnormal range. Ambulatory electrocardiogram monitors placed 24 hours before the preparation and removed after colonoscopy showed no increase in ventricular premature contractions or other serious arrhythmias in either group during preparation or colonoscopy. Conclusions: (1) Sodium Phosphate and SF-PEG-ELS are equally well tolerated and effective in preparation for outpatient colonoscopy, and (2) Sodium Phosphate preparation at the recommended dose causes significant alterations in serum Sodium, potassium, chloride, calcium, ionized calcium, and phosphorus levels. (Gastrointest Endosc 1996;43:42-8.)
Timothy T Nostrant - One of the best experts on this subject based on the ideXlab platform.
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single day divided dose oral Sodium Phosphate laxative versus intestinal lavage as preparation for colonoscopy efficacy and patient tolerance
Gastrointestinal Endoscopy, 1995Co-Authors: Joseph M Henderson, Jeffrey L Barnett, Danielle Kim Turgeon, Grace H Elta, Elizabeth M Behler, Ingrid Crause, Timothy T NostrantAbstract:Polyethylene glycol-electrolyte lavage solutions are widely used to prepare the colon for colonoscopy. Unfortunately, some patients find this preparation difficult to complete. Recent studies of a Sodium Phosphate-based laxative have shown both good patient tolerance and good bowel preparation. In these studies, the laxative has generally been prescribed in two doses, with the second dose taken early the morning of colonoscopy. Because the morning dose is inconvenient for many patients, we compared giving a common polyethylene glycol-based electrolyte lavage solution the day before colonoscopy with our method of giving both doses of Sodium Phosphate-based laxative the day before colonoscopy: one dose at 4 PM and the second dose at 8 PM. We judged efficacy by an assessment of residual liquid and fecal matter in the colon and judged tolerance by the results of a symptom questionnaire completed by each patient immediately before the procedure. Our results in more than 200 patients showed similar efficacy ratings and similar symptom scores for both preparations, but patients rated the Sodium Phosphate-based preparation as easier to tolerate. In conclusion, in selected patients this new dosing method for Sodium Phosphate is preferable to large-volume, whole-gut lavage solutions.
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single day divided dose oral Sodium Phosphate laxative versus intestinal lavage as preparation for colonoscopy efficacy and patient tolerance
Gastrointestinal Endoscopy, 1995Co-Authors: Joseph M Henderson, Jeffrey L Barnett, Danielle Kim Turgeon, Grace H Elta, Elizabeth M Behler, Ingrid Crause, Timothy T NostrantAbstract:Abstract Polyethylene glycol-electrolyte lavage solutions are widely used to prepare the colon for colonoscopy. Unfortunately, some patients find this preparation difficult to complete. Recent studies of a Sodium Phosphate-based laxative have shown both good patient tolerance and good bowel preparation. In these studies, the laxative has generally been prescribed in two doses, with the second dose taken early the morning of colonoscopy. Because the morning dose is inconvenient for many patients, we compared giving a common polyethylene glycol-based electrolyte lavage solution the day before colonoscopy with our method of giving both doses of Sodium Phosphate-based laxative the day before colonoscopy: one dose at 4 PM and the second dose at 8 PM. We judged efficacy by an assessment of residual liquid and fecal matter in the colon and judged tolerance by the results of a symptom questionnaire completed by each patient immediately before the procedure. Our results in more than 200 patients showed similar efficacy ratings and similar symptom scores for both preparations, but patients rated the Sodium Phosphate-based preparation as easier to tolerate. In conclusion, in selected patients this new dosing method for Sodium Phosphate is preferable to large-volume, whole-gut lavage solutions. (Gastrointest Endosc 1995;42:238-43.)
Martin Rose - One of the best experts on this subject based on the ideXlab platform.
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a randomized multicenter study comparing the safety and efficacy of Sodium Phosphate tablets with 2l polyethylene glycol solution plus bisacodyl tablets for colon cleansing
The American Journal of Gastroenterology, 2007Co-Authors: John F. Johanson, Sandra Lottes, William P Forbes, Kelli Walker, Bing Zhang, John Popp, Lawrence B. Cohen, Edwin Carter, Martin RoseAbstract:A Randomized, Multicenter Study Comparing the Safety and Efficacy of Sodium Phosphate Tablets With 2L Polyethylene Glycol Solution Plus Bisacodyl Tablets for Colon Cleansing
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A Randomized, Multicenter Study Comparing the Safety and Efficacy of Sodium Phosphate Tablets With 2L Polyethylene Glycol Solution Plus Bisacodyl Tablets for Colon Cleansing
The American journal of gastroenterology, 2007Co-Authors: John F. Johanson, Sandra Lottes, William P Forbes, Kelli Walker, Bing Zhang, John Popp, Lawrence B. Cohen, Edwin Carter, Martin RoseAbstract:A Randomized, Multicenter Study Comparing the Safety and Efficacy of Sodium Phosphate Tablets With 2L Polyethylene Glycol Solution Plus Bisacodyl Tablets for Colon Cleansing
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safety and colon cleansing efficacy of a new residue free formulation of Sodium Phosphate tablets
The American Journal of Gastroenterology, 2006Co-Authors: Howard Schwartz, Sandra Lottes, Kelli Walker, John Popp, Martin Rose, Michael Goldstein, Seymour Katz, Charles F Barish, Robyn G Karlstadt, N EttingerAbstract:Safety and Colon-Cleansing Efficacy of a New Residue-Free Formulation of Sodium Phosphate Tablets
Stephen Vanner - One of the best experts on this subject based on the ideXlab platform.
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pico salax plus two day bisacodyl is superior to pico salax alone or oral Sodium Phosphate for colon cleansing before colonoscopy
The American Journal of Gastroenterology, 2009Co-Authors: Lawrence Hookey, Stephen VannerAbstract:Pico-Salax Plus Two-Day Bisacodyl Is Superior to Pico-Salax Alone or Oral Sodium Phosphate for Colon Cleansing Before Colonoscopy
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a prospective randomized trial comparing low dose oral Sodium Phosphate plus stimulant laxatives with large volume polyethylene glycol solution for colon cleansing
The American Journal of Gastroenterology, 2004Co-Authors: Lawrence Hookey, William T Depew, Stephen VannerAbstract:A Prospective Randomized Trial Comparing Low-Dose Oral Sodium Phosphate Plus Stimulant Laxatives with Large Volume Polyethylene Glycol Solution for Colon Cleansing
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carbohydrate electrolyte rehydration protects against intravascular volume contraction during colonic cleansing with orally administered Sodium Phosphate
Gastrointestinal Endoscopy, 2002Co-Authors: Robert L Barclay, William T Depew, Stephen VannerAbstract:Abstract Background: Colonic cleansing with Sodium Phosphate causes intravascular volume contraction in some patients. This study tested the hypothesis that carbohydrate-electrolyte oral rehydration would attenuate the hypovolemic changes associated with administration of Sodium Phosphate. Methods: Adult outpatients were randomized to ingest either regular clear fluids or a carbohydrate-electrolyte rehydration solution during precolonoscopy purgation by ingestion of aqueous Sodium Phosphate. Investigators were blinded to the treatment assignment of patients. Clinical hemodynamic measurements and biochemical tests were obtained at baseline and after bowel preparation. Tolerability and colonoscopic visualization were assessed with questionnaires. Results: One hundred sixty-eight patients completed the study (81 clear fluids, 87 rehydration). By comparison with clear fluids, rehydration resulted in significantly less intravascular volume contraction. Changes in estimated central venous pressure and orthostatic pulse were significantly greater in the clear fluid group versus the rehydration group ( p p p = 0.2). Conclusions: Carbohydrate-electrolyte rehydration protects against intravascular volume contraction during preparation for colonoscopy by ingestion of Sodium Phosphate. This approach is well tolerated by patients and improves colonic cleansing. (Gastrointest Endosc 2002;56:633-8.)
Luan D Truong - One of the best experts on this subject based on the ideXlab platform.
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renal failure and nephrocalcinosis associated with oral Sodium Phosphate bowel cleansing clinical patterns and renal biopsy findings
Archives of Pathology & Laboratory Medicine, 2006Co-Authors: Gulfiliz Gonlusen, Hulya Akgun, Atilla Ertan, J J Olivero, Luan D TruongAbstract:c Acute renal failure (ARF) is rarely reported after bowel preparation with Sodium Phosphate. We report a patient with mild Crohn disease (in remission), without history of renal disease, and with normal baseline renal function, who developed ARF 14 days after bowel preparation for colonoscopy with oral Sodium Phosphate. A renal biopsy showed multifocal calcium Phosphate deposition in the renal tubules against a background of diffuse chronic tubulointerstitial injury. Review of the literature suggested 2 distinct patterns of ARF in the context of Sodium Phosphate bowel cleansing. One pattern is characterized by ARF, which develops a few hours or days after Sodium Phosphate administration, as a component of a systemic syndrome associated with severe hyperPhosphatemia and hypocalcemia. Correction of these electrolyte abnormalities was frequently associated with rapid recovery of renal function. The cause of ARF in this context was not clear because the favorable outcome negated the need for renal biopsy. In the second pattern, exemplified by the current patient, ARF was identified incidentally. These patients did not have any features of an acute syndrome immediately after Sodium Phosphate administration and presented much later (usually weeks) with mild, nonspecific symptoms. At the time of presentation, the serum calcium and Phosphate levels were normal. The renal biopsies in each of these patients showed nephrocalcinosis as the possible cause of ARF. The renal failure improved at least partially in most of these patients, but persisted in rare cases. (Arch Pathol Lab Med. 2006;130:101‐106)
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renal failure and nephrocalcinosis associated with oral Sodium Phosphate bowel cleansing clinical patterns and renal biopsy findings
Archives of Pathology & Laboratory Medicine, 2006Co-Authors: Gulfiliz Gonlusen, Hulya Akgun, Atilla Ertan, J J Olivero, Luan D TruongAbstract:Acute renal failure (ARF) is rarely reported after bowel preparation with Sodium Phosphate. We report a patient with mild Crohn disease (in remission), without history of renal disease, and with normal baseline renal function, who developed ARF 14 days after bowel preparation for colonoscopy with oral Sodium Phosphate. A renal biopsy showed multifocal calcium Phosphate deposition in the renal tubules against a background of diffuse chronic tubulointerstitial injury. Review of the literature suggested 2 distinct patterns of ARF in the context of Sodium Phosphate bowel cleansing. One pattern is characterized by ARF, which develops a few hours or days after Sodium Phosphate administration, as a component of a systemic syndrome associated with severe hyperPhosphatemia and hypocalcemia. Correction of these electrolyte abnormalities was frequently associated with rapid recovery of renal function. The cause of ARF in this context was not clear because the favorable outcome negated the need for renal biopsy. In the second pattern, exemplified by the current patient, ARF was identified incidentally. These patients did not have any features of an acute syndrome immediately after Sodium Phosphate administration and presented much later (usually weeks) with mild, nonspecific symptoms. At the time of presentation, the serum calcium and Phosphate levels were normal. The renal biopsies in each of these patients showed nephrocalcinosis as the possible cause of ARF. The renal failure improved at least partially in most of these patients, but persisted in rare cases.
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renal failure and nephrocalcinosis associated with oral Sodium Phosphate bowel cleansing clinical patterns and renal biopsy findings
Archives of Pathology & Laboratory Medicine, 2006Co-Authors: Gulfiliz Gonlusen, Hulya Akgun, Atilla Ertan, J J Olivero, Luan D TruongAbstract:Abstract Acute renal failure (ARF) is rarely reported after bowel preparation with Sodium Phosphate. We report a patient with mild Crohn disease (in remission), without history of renal disease, an...
