The Experts below are selected from a list of 4032 Experts worldwide ranked by ideXlab platform
Timothy J Egan - One of the best experts on this subject based on the ideXlab platform.
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Porcine Small Intestine Submucosa for Soft Tissue Augmentation
Dermatologic Surgery, 2004Co-Authors: Jeffrey H Spiegel, Timothy J EganAbstract:Objective. Porcine small intestine submucosa was evaluated as a material for Soft Tissue Augmentation in the hairless guinea pig model. Materials and Methods. Small intestine submucosa was formed into strips and rolls and implanted into the dorsum of the hairless guinea pig. The animals were divided into three groups and the implants were evaluated grossly and microscopically for persistence, infection, and inflammation. A total of 116 implants were evaluated grossly. Results. Selected samples from the 1- and 3-month cohorts and all identifiable samples from the 5-month cohort were evaluated microscopically. Some implants were not located, likely due to migration. With one exception, the identified implants in the 5-month cohort exhibited minimal inflammation and appeared well tolerated. The eight-ply small intestine submucosa material appears well tolerated and provided increased Soft Tissue volume at 5 months. Conclusion. Small intestine submucosa may represent an alternative to autologous and homologous materials for Soft Tissue Augmentation.
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Porcine small intestine submucosa for Soft Tissue Augmentation.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004Co-Authors: Jeffrey H Spiegel, Timothy J EganAbstract:Porcine small intestine submucosa was evaluated as a material for Soft Tissue Augmentation in the hairless guinea pig model. Small intestine submucosa was formed into strips and rolls and implanted into the dorsum of the hairless guinea pig. The animals were divided into three groups and the implants were evaluated grossly and microscopically for persistence, infection, and inflammation. A total of 116 implants were evaluated grossly. Selected samples from the 1- and 3-month cohorts and all identifiable samples from the 5-month cohort were evaluated microscopically. Some implants were not located, likely due to migration. With one exception, the identified implants in the 5-month cohort exhibited minimal inflammation and appeared well tolerated. The eight-ply small intestine submucosa material appears well tolerated and provided increased Soft Tissue volume at 5 months. Small intestine submucosa may represent an alternative to autologous and homologous materials for Soft Tissue Augmentation.
Jeffrey H Spiegel - One of the best experts on this subject based on the ideXlab platform.
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Porcine Small Intestine Submucosa for Soft Tissue Augmentation
Dermatologic Surgery, 2004Co-Authors: Jeffrey H Spiegel, Timothy J EganAbstract:Objective. Porcine small intestine submucosa was evaluated as a material for Soft Tissue Augmentation in the hairless guinea pig model. Materials and Methods. Small intestine submucosa was formed into strips and rolls and implanted into the dorsum of the hairless guinea pig. The animals were divided into three groups and the implants were evaluated grossly and microscopically for persistence, infection, and inflammation. A total of 116 implants were evaluated grossly. Results. Selected samples from the 1- and 3-month cohorts and all identifiable samples from the 5-month cohort were evaluated microscopically. Some implants were not located, likely due to migration. With one exception, the identified implants in the 5-month cohort exhibited minimal inflammation and appeared well tolerated. The eight-ply small intestine submucosa material appears well tolerated and provided increased Soft Tissue volume at 5 months. Conclusion. Small intestine submucosa may represent an alternative to autologous and homologous materials for Soft Tissue Augmentation.
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Porcine small intestine submucosa for Soft Tissue Augmentation.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004Co-Authors: Jeffrey H Spiegel, Timothy J EganAbstract:Porcine small intestine submucosa was evaluated as a material for Soft Tissue Augmentation in the hairless guinea pig model. Small intestine submucosa was formed into strips and rolls and implanted into the dorsum of the hairless guinea pig. The animals were divided into three groups and the implants were evaluated grossly and microscopically for persistence, infection, and inflammation. A total of 116 implants were evaluated grossly. Selected samples from the 1- and 3-month cohorts and all identifiable samples from the 5-month cohort were evaluated microscopically. Some implants were not located, likely due to migration. With one exception, the identified implants in the 5-month cohort exhibited minimal inflammation and appeared well tolerated. The eight-ply small intestine submucosa material appears well tolerated and provided increased Soft Tissue volume at 5 months. Small intestine submucosa may represent an alternative to autologous and homologous materials for Soft Tissue Augmentation.
Anton Sculean - One of the best experts on this subject based on the ideXlab platform.
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Soft Tissue Augmentation procedures at second-stage surgery: a systematic review
Clinical Oral Investigations, 2016Co-Authors: Renzo G. Bassetti, Alexandra Stähli, Mario A. Bassetti, Anton SculeanAbstract:Objectives The aim of this systematic review was to evaluate the efficacy of different Soft Tissue Augmentation/correction methods in terms of increasing the peri-implant width of keratinized mucosa (KM) and/or gain of Soft Tissue volume during second-stage surgery. Materials and methods Screening of two databases, MEDLINE (PubMed) and EMBASE (OVID), and hand search of related articles, were performed. Human studies reporting on Soft Tissue Augmentation/correction methods around submucosally osseointegrated implants during second-stage surgery up to July 31, 2015 were considered. Quality assessment of the selected full-text articles was performed according to the Cochrane collaboration’s tool to assess the risk of bias. Results Overall, eight prospective studies (risk of bias: high) and two case series (risk of bias: high) were included. Depending on the surgical technique and graft material used, the enlargement of keratinized Tissue (KT) ranged between −0.20 and 9.35 mm. An apically positioned partial-thickness flap/vestibuloplasty (APPTF/VP) in combination with a free gingival graft (FGG) or a xenogeneic graft material (XCM) was most effective. Applying a roll envelope flap (REF) or an APPTF in combination with a subepithelial connective Tissue graft (SCTG), mean increases in Soft Tissue volumes of 2.41 and 3.10 mm, respectively, were achieved. Due to the heterogeneity of study designs, no meta-analysis could be performed. Conclusions Within the limitations of this review, regarding the enlargement of peri-implant KT, the APPTF in the maxilla and the APPTF/VP in combination with FGG or XCM in the lower and upper jaw seem to provide acceptable outcomes. To augment peri-implant Soft Tissue volume REF in the maxilla or APPTF + SCTG in the lower and upper jaw appear to be reliable treatment options. Clinical relevance The localization in the jaw and the clinical situation are crucial for the decision which second-stage procedure should be applied.
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Soft Tissue Augmentation procedures at second-stage surgery: a systematic review.
Clinical oral investigations, 2016Co-Authors: Renzo Bassetti, Alexandra Stähli, Mario Bassetti, Anton SculeanAbstract:Objectives The aim of this systematic review was to evaluate the efficacy of different Soft Tissue Augmentation/correction methods in terms of increasing the peri-implant width of keratinized mucosa (KM) and/or gain of Soft Tissue volume during second-stage surgery.
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Indication and timing of Soft Tissue Augmentation at maxillary and mandibular incisors in orthodontic patients. A systematic review.
European journal of orthodontics, 2013Co-Authors: Dimitrios Kloukos, Anton Sculean, Theodore Eliades, Christos KatsarosAbstract:OBJECTIVE To assess the indication and timing of Soft Tissue Augmentation for prevention or treatment of gingival recession when a change in the inclination of the incisors is planned during orthodontic treatment. MATERIALS AND METHODS Electronic database searches of literature were performed. The following electronic databases with no restrictions were searched: MEDLINE, EMBASE, Cochrane, and CENTRAL. Two authors performed data extraction independently using data collection forms. RESULTS No randomized controlled trial was identified. Two studies of low-to-moderate level of evidence were included: one of prospective and retrospective data collection and one retrospective study. Both implemented a periodontal intervention before orthodontics. Thus, best timing of Soft Tissue Augmentation could not be assessed. The limited available data from these studies appear to suggest that Soft Tissue Augmentation of bucco-lingual gingival dimensions before orthodontics may yield satisfactory results with respect to the development or progression of gingival recessions. However, the strength of the available evidence is not adequate in order to change or suggest a possible treatment approach in the daily practice based on solid scientific evidence. CONCLUSIONS Despite the clinical experience that Soft Tissue Augmentation of bucco-lingual gingival dimensions before orthodontic treatment may be a clinically viable treatment option in patients considered at risk, this treatment approach is not based on solid scientific evidence. Moreover, the present data do not allow to draw conclusions on the best timing of Soft Tissue Augmentation when a change in the inclination of the incisors is planned during orthodontic treatment and thus, there is a stringent need for randomized controlled trials to clarify these open issues.
Alexandra Stähli - One of the best experts on this subject based on the ideXlab platform.
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Soft Tissue Augmentation procedures at second-stage surgery: a systematic review
Clinical Oral Investigations, 2016Co-Authors: Renzo G. Bassetti, Alexandra Stähli, Mario A. Bassetti, Anton SculeanAbstract:Objectives The aim of this systematic review was to evaluate the efficacy of different Soft Tissue Augmentation/correction methods in terms of increasing the peri-implant width of keratinized mucosa (KM) and/or gain of Soft Tissue volume during second-stage surgery. Materials and methods Screening of two databases, MEDLINE (PubMed) and EMBASE (OVID), and hand search of related articles, were performed. Human studies reporting on Soft Tissue Augmentation/correction methods around submucosally osseointegrated implants during second-stage surgery up to July 31, 2015 were considered. Quality assessment of the selected full-text articles was performed according to the Cochrane collaboration’s tool to assess the risk of bias. Results Overall, eight prospective studies (risk of bias: high) and two case series (risk of bias: high) were included. Depending on the surgical technique and graft material used, the enlargement of keratinized Tissue (KT) ranged between −0.20 and 9.35 mm. An apically positioned partial-thickness flap/vestibuloplasty (APPTF/VP) in combination with a free gingival graft (FGG) or a xenogeneic graft material (XCM) was most effective. Applying a roll envelope flap (REF) or an APPTF in combination with a subepithelial connective Tissue graft (SCTG), mean increases in Soft Tissue volumes of 2.41 and 3.10 mm, respectively, were achieved. Due to the heterogeneity of study designs, no meta-analysis could be performed. Conclusions Within the limitations of this review, regarding the enlargement of peri-implant KT, the APPTF in the maxilla and the APPTF/VP in combination with FGG or XCM in the lower and upper jaw seem to provide acceptable outcomes. To augment peri-implant Soft Tissue volume REF in the maxilla or APPTF + SCTG in the lower and upper jaw appear to be reliable treatment options. Clinical relevance The localization in the jaw and the clinical situation are crucial for the decision which second-stage procedure should be applied.
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Soft Tissue Augmentation procedures at second-stage surgery: a systematic review.
Clinical oral investigations, 2016Co-Authors: Renzo Bassetti, Alexandra Stähli, Mario Bassetti, Anton SculeanAbstract:Objectives The aim of this systematic review was to evaluate the efficacy of different Soft Tissue Augmentation/correction methods in terms of increasing the peri-implant width of keratinized mucosa (KM) and/or gain of Soft Tissue volume during second-stage surgery.
Hom-lay Wang - One of the best experts on this subject based on the ideXlab platform.
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Palatal Pedicle Flaps for Soft Tissue Augmentation.
The International journal of periodontics & restorative dentistry, 2020Co-Authors: Edward Shih-chang Tseng, Lorenzo Tavelli, Hom-lay WangAbstract:Several approaches for peri-implant Soft Tissue Augmentation have been proposed, including autogenous Soft Tissue grafts and substitutes. Palatal pedicle flaps have been introduced for increasing facial Soft Tissue thickness, improving esthetics, and achieving primary closure following alveolar ridge preservation or guided bone regeneration. The main advantage of these approaches is to maintain the vascularization of the flap, which may result in better healing and less shrinkage than graft-based procedures. Nevertheless, different clinical scenarios require different palatal pedicle flaps. The aim of this article was to present several palatal pedicle flap techniques for peri-implant Soft Tissue Augmentation and alveolar ridge preservation, showing flap designs and the main advantages through case presentations.
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Living cell-based regenerative medicine technologies for periodontal Soft Tissue Augmentation.
Journal of periodontology, 2019Co-Authors: Michael K. Mcguire, Giovanni Zucchelli, Hom-lay Wang, Lorenzo Tavelli, Stephen E. Feinberg, Giulio Rasperini, William V. GiannobileAbstract:The cultivation of human living cells into scaffolding matrices has progressively gained popularity in the field of periodontal wound healing and regeneration. Living cellular constructs based on fibroblasts, keratinocytes alone or in combination have been developed and used as alternatives to autogenous Soft Tissue grafts in keratinized Tissue Augmentation and in root coverage procedures. Their promising advantages include reduced patient morbidity, unlimited graft availability, and comparable esthetics. This manuscript reviews Soft Tissue Augmentation and root coverage procedures using bioengineered living cellular therapy and highlights their expected clinical, esthetic, and patient-related outcomes.
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Impact of timing on Soft Tissue Augmentation during implant treatment: A systematic review and meta-analysis.
Clinical oral implants research, 2018Co-Authors: Cho Ying Lin, Zhaozhao Chen, Whei Lin Pan, Hom-lay WangAbstract:Background To achieve a predictable esthetic and functional outcome, Soft Tissue Augmentation has become popular in implant treatment. Objectives The aim of this systematic review and meta-analysis was to assess the influence of different timing for Soft Tissue Augmentation during implant treatment on Soft Tissue conditions and its stability. Material and methods Electronic and manual searches for articles written in English up to September 2017 were performed by two independent reviewers. Human clinical studies with the purpose of evaluating outcomes (at least 3-month follow-up) of autogenous Soft Tissue graft for Augmentation during implant treatment, either simultaneous or after implant placement (staged), were included. Cumulative changes of keratinized Tissue width (KTW), Soft Tissue thickness (STT), and mid-buccal mucosal recession (MR) data were analyzed with a random-effects model to compare the postoperative outcomes. Results Twenty-nine human studies (eight randomized clinical trials, six cohort studies, and 15 case series) that met the inclusion criteria were included. For the overall data, the weighted mean STT gain (1 year after surgery) was 1.03 mm (95% CI: 0.78-1.29 mm), among which the simultaneous group was 1.12 mm (95% CI: 0.75-1.49 mm) and staged group (3-6 months after implant placement) was 0.95 mm (95% CI: 0.58-1.31 mm). There was no statistically significant difference in KTW and MR between 3 months and more than 3 months after surgery. Conclusions This review revealed that the stability of Soft Tissue, in terms of KTW and mid-buccal MR, can be obtained 3 months after surgery. There is no difference between simultaneous and staged Soft Tissue Augmentation during implant treatment, and both procedures significantly enhance KTW and STT.
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Pouch roll technique for implant Soft Tissue Augmentation: a variation of the modified roll technique.
The International journal of periodontics & restorative dentistry, 2012Co-Authors: Sang-hoon Park, Hom-lay WangAbstract:This paper presents three cases of peri-implant mucosal defects that were successfully treated with a newly proposed "pouch roll" implant Soft Tissue Augmentation technique. This procedure uses a de-epithelialized connective Tissue layer during the first or second stage of implant surgery over the underlying dental implant without the need for sutures. At 2 weeks, healing was remarkable, with excellent plaque control. At 3 months, only minimal Tissue shrinkage was evident. As a result, a 2- to 3-mm increase in the width of the keratinized Tissue was noted around the augmented implant site. This technique is an atraumatic, versatile, and cost-effective surgical modality that enhances the peri-implant Soft Tissue over the ridge with a Soft Tissue thickness ≥ 3 mm. The pouch roll implant Soft Tissue Augmentation procedure provides an easy and less traumatic correction of a mild to moderate buccal ridge deficiency by thickening the Soft Tissue around the dental implant.
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Dermal Fillers for Facial Soft Tissue Augmentation
The Journal of oral implantology, 2007Co-Authors: Sarosh F. Dastoor, Carl E. Misch, Hom-lay WangAbstract:Abstract Nowadays, patients are demanding not only enhancement to their dental (micro) esthetics, but also their overall facial (macro) esthetics. Soft Tissue Augmentation via dermal filling agents may be used to correct facial defects such as wrinkles caused by age, gravity, and trauma; thin lips; asymmetrical facial appearances; buccal fold depressions; and others. This article will review the pathogenesis of facial wrinkles, history, techniques, materials, complications, and clinical controversies regarding dermal fillers for Soft Tissue Augmentation.