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Yuewei Guo - One of the best experts on this subject based on the ideXlab platform.
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a new cyclic peptide and a new steroid from the fungus penicillium sp gd6 isolated from the mangrove Bruguiera gymnorrhiza
Helvetica Chimica Acta, 2014Co-Authors: Zhen Fang Zhou, Xiaohong Yang, Haili Liu, Yuewei GuoAbstract:A rare new cyclic tetrapeptide, 5,5′-epoxy-MKN-349A (1), featured by a MKN-349A (5) skeleton and containing an uncommon ether bridge between C(5) and C(5′), and a new steroid, named 11-O-acetyl-NGA0187 (2), together with two known steroids, 3 and 4, were isolated from an endophytic fungus Penicillium sp. GD6 associated with the Chinese mangrove Bruguiera gymnorrhiza. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analyses and by comparison with the data of related compounds reported in literature. Neither of the compounds 3 and 4, isolated in this study, showed obvious bioactivities in the antibacterial bioassay experiments.
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cyclopenol a new naturally occurring 7 membered 2 5 dioxopiperazine alkaloid from the fungus penicillium sclerotiorum endogenous with the chinese mangrove Bruguiera gymnorrhiza
Journal of Asian Natural Products Research, 2014Co-Authors: Jun Wang, Chengshi Jiang, Yuewei GuoAbstract:One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergosterol (9), and ergosterol peroxide (10), was isolated from the EtOAc extract of fungus Penicillium sclerotiorum, an endophytic fungal strain isolated from Chinese mangrove Bruguiera gymnorrhiza. The chemical structure of the new compound 1 was elucidated on the basis of detailed spectroscopic analysis. The absolute configuration of 1 was determined by single-crystal X-ray analysis with Cu Kα radiation (λ = 1.54178 A). To our knowledge, (+)-cyclopenol (1) represents the first example of 7-membered 2,5-dioxopiperazine isolated from mangrove endophytic fungus.
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palmarumycins bg1 bg7 and preussomerin bg1 establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra
Journal of Organic Chemistry, 2011Co-Authors: You Sheng Cai, Tibor Kurtan, Attila Mandi, Haili Liu, Miao Zehong, Istvan Komaromi, Jian Ding, Yuewei GuoAbstract:Palmarumycins BG1−BG7 (1−7), seven new compounds related to palmarumycins, were isolated from the aerial parts of Bruguiera gymnorrhiza as well as a new preussomerin derivative BG1 (8). The structures of these compounds were determined mainly by the analysis of their NMR and MS data, and their relative configurations were assigned on the basis of their 3JH,H coupling constants. Compounds 4 and 7 have a sulfate group that is unprecedented among members of spirodioxynaphthalene-type natural products. The absolute configurations of 1−8 were determined by TDDFT CD calculations of the solution conformers. Compound 5 displayed inhibitory activity against HL 60 and MCF-7 cell lines.
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sexangulic acid a new cytotoxic triterpenoid from the chinese mangrove Bruguiera sexangula
Natural Product Research, 2010Co-Authors: Caiguo Huang, Changyun Wang, Yuewei GuoAbstract:A new cytotoxic lanostane-type triterpenoid, sexangulic acid (1), has been isolated from mangrove Bruguiera sexangula. The structure of the new compound was elucidated on the basis of chemical reaction and the analysis of spectroscopic data.
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diastereoisomeric macrocyclic polydisulfides from the mangrove Bruguiera gymnorrhiza
Phytochemistry, 2009Co-Authors: Xiaoying Huang, Qi Wang, Haili Liu, Yu Zhang, Guorong Xin, Xu Shen, Meiling Dong, Yuewei GuoAbstract:Abstract The uncommon macrocyclic polydisulfides, trans -3,3′-dihydroxy-1,5,1′,5′-tetrathiacyclodecane ( 1 ), cis -3,3′-dihydroxy-1,5,1′,5′-tetrathiacyclodecane ( 2 ), along with five known related cyclic disulfides, gymnorrhizol ( 3 ), neogymnorrhizol ( 4 ), bruguiesulfurol ( 5 ), brugierol ( 6 ), and isobrugierol ( 7 ), were isolated from the mangrove Bruguiera gymnorrhiza collected from Guangdong Province, China. Structures of compounds 1 and 2 were determined by extensive analysis of their spectroscopic data, by comparison of their NMR spectroscopic data with those of the co-occurring known compounds, as well as by single-crystal X-ray diffraction analysis. A possible biogenetic origin was also proposed.
Baderan D. K. - One of the best experts on this subject based on the ideXlab platform.
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Struktur Vegetasi dan Zonasi Mangrove di Wilayah Pesisir Kecamatan Kwandang Kabupaten Gorontalo Utara Provinsi Gorontalo
'Hasanuddin University Faculty of Law', 2019Co-Authors: Baderan D. K.Abstract:Ekosistem hutan mangrove bersifat kompleks dan dinamis, namun juga labil. Dikatakan kompleks karena ekosistemnya dipenuhi oleh vegetasi mangrove, juga merupakan habitat berbagai satwa dan biota perairan. Ekosistem mangrove adalah suatu sistem di alam tempat berlangsungnya kehidupan yang mencerminkan hubungan timbal Balik antara makhluk hidup dengan lingkungannya dan diantara makhluk hidup itu sendiri, terdapat pada wilayah pesisir, terpengaruh pasang surut air laut, dan didominasi oleh spesies pohon atau semak yang khas dan mampu tumbuh dalam perairan asin/payau. Penelitian ini bertujuan untuk mengetahui struktur vegetasi dan zonasi mangrove di wilayah pesisir Kecamatan Kwandang Kabupaten Gorontalo Utara Provinsi Gorontalo. Pengambilan data struktur vegetasi mangrove dengan cara membuat transek segi empat dengan panjang transek dibuat dengan ukuran 30 m x30 m (total transek sebanyak 31 transek).Hasil penelitian menemukan 16 spesies yang mendiami hutan mangrove di wilayah pesisir Kecamatan Kwandang Kabupaten Gorontalo Utara yakni spesies Rhizophora mucronata Blume, Rhizophora Apiculata Lamk, Ceriops decandra (Griff.) Ding Hou, Ceriops tagal (Perr.) C.B.Rob, Brugueira gymnorrhiza (L) Lamk, Bruguiera paviflora (Roxb) W&A, Sonneratia alba J.E. Smith, Soneratia caseolaris (L) Eng, Xylocarpus mulocensis (Lamk) Roem, Xylocarpus granatum Koen (niri), Avecennia alba Blume, Avecennia marina (Forsk) Vierh, Avicennia officinalis (L) Lamk, Acanthus ilicifolius L, Heritiera littoralis Dryand. Ex W.Ait, Aegiceras corniculatum (L.) Blanco.Profil zonasi di wilayah ini masuk pada zonasi sederhana (satu zonasi atau zonasi campuran) dimana dari pinggir pantai sampai pedalaman daratan setiap spesies saling berasosiasi dalam satu lapisan. Profil zonasi di wilayah pesisir Kecamatan Kwandang tidak terdiri atas beberapa zonasi, karena tidak ada zonasi yang murni satu genus saja, yang ditemukan hanya satu zonasi yang merupakan campuran (mixel), dimana setiap spesies tumbuh berulang sampai kearah daratan, dan tumbuh saling bercampur antara 16 spesies tersebut.Keseluruhan spesies yang ditemukan terdapat spesies Ceriops decandra yang merupakan spesies langka secara global sehingga diperlukan perhatian khusus dalam pengelolaan hutan mangrove di wilayah pesisir Kecamatan Kwandang
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STRUKTUR VEGETASI DAN ZONASI MANGROVE DI WILAYAH PESISIR KECAMATAN KWANDANG KABUPATEN GORONTALO UTARA PROVINSI GORONTALO
'Hasanuddin University Faculty of Law', 2019Co-Authors: Baderan D. K.Abstract:Ekosistem hutan mangrove bersifat kompleks dan dinamis, namun juga labil. Dikatakan kompleks karena ekosistemnya dipenuhi oleh vegetasi mangrove, juga merupakan habitat berbagai satwa dan biota perairan. Ekosistem mangrove adalah suatu sistem di alam tempat berlangsungnya kehidupan yang mencerminkan hubungan timbal balik antara makhluk hidup dengan lingkungannya dan diantara makhluk hidup itu sendiri, terdapat pada wilayah pesisir, terpengaruh pasang surut air laut, dan didominasi oleh spesies pohon atau semak yang khas dan mampu tumbuh dalam perairan asin/payau. Penelitian ini bertujuan untuk mengetahui struktur vegetasi dan zonasi mangrove di wilayah pesisir Kecamatan Kwandang Kabupaten Gorontalo Utara Provinsi Gorontalo. Pengambilan data struktur vegetasi mangrove dengan cara membuat transek segi empat dengan panjang transek dibuat dengan ukuran 30 m x30 m (total transek sebanyak 31 transek).Hasil penelitian menemukan 16 spesies yang mendiami hutan mangrove di wilayah pesisir Kecamatan Kwandang Kabupaten Gorontalo Utara yakni spesies Rhizophora mucronata Blume, Rhizophora Apiculata Lamk, Ceriops decandra (Griff.) Ding Hou, Ceriops tagal (Perr.) C.B.Rob, Brugueira gymnorrhiza (L) Lamk, Bruguiera paviflora (Roxb) W&A, Sonneratia alba J.E. Smith, Soneratia caseolaris (L) Eng, Xylocarpus mulocensis (Lamk) Roem, Xylocarpus granatum Koen (niri), Avecennia alba Blume, Avecennia marina (Forsk) Vierh, Avicennia officinalis (L) Lamk, Acanthus ilicifolius L, Heritiera littoralis Dryand. Ex W.Ait, Aegiceras corniculatum (L.) Blanco.Profil zonasi di wilayah ini masuk pada zonasi sederhana (satu zonasi atau zonasi campuran) dimana dari pinggir pantai sampai pedalaman daratan setiap spesies saling berasosiasi dalam satu lapisan. Profil zonasi di wilayah pesisir Kecamatan Kwandang tidak terdiri atas beberapa zonasi, karena tidak ada zonasi yang murni satu genus saja, yang ditemukan hanya satu zonasi yang merupakan campuran (mixel), dimana setiap spesies tumbuh berulang sampai kearah daratan, dan tumbuh saling bercampur antara 16 spesies tersebut.Keseluruhan spesies yang ditemukan terdapat spesies Ceriops decandra yang merupakan spesies langka secara global sehingga diperlukan perhatian khusus dalam pengelolaan hutan mangrove di wilayah pesisir Kecamatan Kwandang.Kata Kunci : Struktur Vegetasi, Zonasi, Spesies Mangrove
Wenhan Lin - One of the best experts on this subject based on the ideXlab platform.
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divergolides a d from a mangrove endophyte reveal an unparalleled plasticity in ansa macrolide biosynthesis
Angewandte Chemie, 2011Co-Authors: Ling Ding, Wenhan Lin, Armin Maier, Heinzherbert Fiebig, Helmar Gorls, Gundela Peschel, Christian HertweckAbstract:Herein we report the isolation, structure elucidation, andbiologicalactivitiesoffournovelansamacrolides,whichpointtoahighly divergentbiosynthetic pathwayin an endophyte ofthe mangrove tree Bruguiera gymnorrhiza. B. gymnorrhiza isone of the dominant mangrove species along the Chinesecoast, and in Chinese traditional medicine the bark and theroot of the tree is used to treat diarrhea, throat inflammation,and hemostasia.
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xiamycin a pentacyclic indolosesquiterpene with selective anti hiv activity from a bacterial mangrove endophyte
Bioorganic & Medicinal Chemistry Letters, 2010Co-Authors: Ling Ding, Wenhan Lin, Armin Maier, Heinzherbert Fiebig, Jan Munch, Helmar Goerls, Christian HertweckAbstract:A novel pentacyclic indolosesquiterpene, named xiamycin (1), and its methyl ester (2) have been obtained from Streptomyces sp. GT2002/1503, an endophyte from the mangrove plant Bruguiera gymnorrhiza. The structures were established by 1D and 2D NMR, MS, and X-ray crystallography, and the absolute configuration of 1 was elucidated by the modified Mosher method. Compound 1 exhibits selective anti-HIV activity; it specifically blocks R5 but has no effects on X4 tropic HIV-1 infection. In a panel of cytotoxicity assays, compound 2 showed to be more potent (geometric mean IC(50)=10.13 μM) compared to compound 1 (geometric mean IC(50) >30 μM), with antitumor potency being generally less pronounced. Xiamycin represents one of the first examples of indolosesquiterpenes isolated from prokaryotes.
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rhyncosides a f phenolic constituents from the chinese mangrove plant Bruguiera sexangula var rhynchopetala
ChemInform, 2008Co-Authors: Shuyun Bao, Yi Ding, Zhiwei Deng, Peter Proksch, Wenhan LinAbstract:Chemical investigation on the stem of a Chinese mangrove plant Bruguiera sexangula var. rhynchopetala (Rhizophoraceae) resulted in the isolation and characterization of four new phenolic glycosides rhyncosides A-D (1-4), and two new lignan derivatives namely rhyncosides E-F (5-6), along with twelve known phenolic constituents. Their structures were determined by extensive spectroscopic data analyses.
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two new constituents from mangrove Bruguiera gymnorrhiza
Journal of Asian Natural Products Research, 2007Co-Authors: L Han, Isabel Sattler, Susanne Grabley, X S Huang, Wenhan LinAbstract:A lignan and two aromatic compounds were isolated from the branches of the mangrove plant, Bruguiera gymnorrhiza. They were brugunin A (1), bruguierol D (2) and 2,3-dimethoxy-5-propylphenol (3). Among them, 1 and 2 were new compounds; 3 was isolated from a natural source for the first time. The structures of these compounds were determined by NMR spectroscopic studies as well as chemical evidence.
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diterpenes and disulfides from the marine mangrove plant Bruguiera sexangula var rhynchopetala
Helvetica Chimica Acta, 2005Co-Authors: Shuyun Bao, Zhiwei Deng, Peter Proksch, Wenhan LinAbstract:Phytochemical investigation of the stems of Bruguiera sexangula var. rhynchopetala resulted in the isolation and characterization of four new and seven known secondary metabolites. The new compounds were spectroscopically identified as 17-hydroxy-16-oxobeyer-9(11)-en-19-al (1), 16,17-dihydroxy-19-nor-ent-kaur-9(11)-en-3-one (2), (16R)-13,17-epoxy-16-hydroxy-ent-kaur-9(11)-en-19-al (3), and (−)-3,4-dihydro-3-hydroxy-7-methoxy-2H-1,5-benzodithiepine-6,9-dione (10). The configurations of the known compounds brugierol (11) and isobrugierol (12) were re-investigated. Compounds 11 and 12, together with 2,6-dimethoxy-1,4-benzoquinone (13), are proposed to be degradation products of the novel, unusual disulfide 10 (Scheme).
Guangying Chen - One of the best experts on this subject based on the ideXlab platform.
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dihydroisocoumarins from the mangrove derived fungus penicillium citrinum
Marine Drugs, 2016Co-Authors: Guolei Huang, Xueming Zhou, Meng Bai, Yuxin Liu, Yanlei Zhao, Youping Luo, Yanyan Niu, Caijuan Zheng, Guangying ChenAbstract:Three new dihydroisocoumarin penicimarins G–I (1–3), together with one known dihydroisocoumarin (4) and three known meroterpenoids (5–7), were obtained from a fungus Penicillium citrinum isolated from the mangrove Bruguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of spectroscopic data. The absolute configuration of 1 was determined by the X-ray diffraction analysis using Cu Kα radiation. The absolute configurations of 2 and 3 were determined by comparison of their circular dichroism (CD) spectra with the literature. All compounds were evaluated for their antibacterial activities and cytotoxic activities.
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structure and absolute configuration of aspergilumamide a a novel lumazine peptide from the mangrove derived fungus aspergillus sp
ChemInform, 2015Co-Authors: Caijuan Zheng, Guangying Chen, Xinming Song, Zhigang Niu, Xiaoping Song, Changyun WangAbstract:A novel lumazine peptide, aspergilumamide A (1), as well as a known analog penilumamide (2), were isolated from the mycelia of a marine-derived fungus Aspergillus sp. (33241), obtained from the mangrove Bruguiera sexangula var. rhynchopetala collected from the South China Sea. The structure of 1 was identified by comprehensive spectroscopic analysis, including 1D- and 2D-NMR, ESI-MS, and MS/MS experiments. The absolute configuration of 1 was determined by Marfey's method.
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bioactive anthraquinone derivatives from the mangrove derived fungus stemphylium sp 33231
Journal of Natural Products, 2014Co-Authors: Xueming Zhou, Caijuan Zheng, Guangying Chen, Xiaoping Song, Changri Han, Wenhao Chen, Zhigang NiuAbstract:Four new anthraquinone derivatives (1–4) and four new alterporriol-type anthranoid dimers (14–17), along with 17 analogues, were isolated from the solid rice fermentation of the fungus Stemphylium sp. 33231 obtained from the mangrove Bruguiera sexangula var. rhynchopetala collected from the South China Sea. Their structures were elucidated using comprehensive spectroscopic methods. The absolute configurations of 1, 3, and 4 were determined by single-crystal X-ray diffraction of their derivatives (1a, 3b, and 4a). The absolute configurations of the chiral 17–19 were determined by comparing their CD spectra with 21. The inhibitory activities of most of the compounds against seven terrestrial pathogenic bacteria and two cancer cell lines were evaluated.
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Antibacterial α-pyrone derivatives from a mangrove-derived fungus Stemphylium sp. 33231 from the South China Sea
The Journal of antibiotics, 2014Co-Authors: Xueming Zhou, Caijuan Zheng, Xiaoping Song, Changri Han, Wenhao Chen, Guangying ChenAbstract:Two new α-pyrone derivatives, infectopyrones A (1) and B (2), were obtained from the EtOAc extract of the endophytic fungus Stemphylium sp. 33231 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds 1 and 2 were evaluated for their antibacterial activities, and they had a broad spectrum of antibacterial activity against five terrestrial pathogenic bacteria.
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two new dihydroisocoumarins from the endophytic fungus aspergillus sp collected from the south china sea
Chemistry of Natural Compounds, 2012Co-Authors: Meiyan Wei, Guangying Chen, Yongcheng LinAbstract:Two new dihydroisocoumarin derivatives, aspergillumarins A and B (1 and 2), were isolated from the culture broth of a marine-derived fungus Aspergillus sp., which was isolated from the fresh leaf of the mangrove tree Bruguiera gymnorrhiza collected from the South China Sea. The structures of compounds 1 and 2 were established by comprehensive analysis of the spectral data, especially 2D NMR spectra results. Compounds 1 and 2 showed weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis at a concentration of 50 μg/mL.
Nobutaka Hanagata - One of the best experts on this subject based on the ideXlab platform.
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sequencing and analysis of 14 842 expressed sequence tags of burma mangrove Bruguiera gymnorrhiza
Plant Science, 2006Co-Authors: Masashi Miyama, Hidetsugu Shimizu, Masahide Sugiyama, Nobutaka HanagataAbstract:We describe here sequencing and analysis of expressed sequence tags (ESTs) generated from burma mangrove, Bruguiera gymnorrhiza. A total of 26,400 cDNA were partially sequenced from five different cDNA libraries constructed from the leaves and roots. These sequences were processed into 14,842 high-quality sequences. Clustering and assembling of these sequences resulted in 6943 unique genes. Blast searches show that 4339 (62.5%) genes had a similarity with known proteins in UniProt database. Of these, 2074 genes are assigned in at least one Gene Ontology terms. Expression profiles are generated based on EST frequency in each cDNA library. The profile suggested co-expression and organ specific gene regulations.
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fructose 2 6 bisphosphate contents were increased in response to salt water and osmotic stress in leaves of Bruguiera gymnorrhiza by differential changes in the activity of the bifunctional enzyme 6 phosphofructo 2 kinase fructose 2 6 bisphosphate 2 phosphatase
Plant Molecular Biology, 2003Co-Authors: Toshiaki Banzai, Nobutaka Hanagata, Zvy Dubinsky, Isao KarubeAbstract:The steady-state level of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate 2-phosphatase (F6P2K/F26BPase) transcript has been found to be raised in the mangrove Bruguiera gymnorrhiza treated with 500 mM NaCl for 6 h. In the present study, we assayed both F6P2K/F26BPase activity and fructose-2,6-bisphosphate (F26BP) contents in leaves of salt- and water-stressed B. gymnorrhiza. In the plants treated with 500 mM NaCl, no increase in transcript level was observed after 1 day of treatment, while both the ratio between F6P2K and F26BPase activity (K/P ratio) and leaf F26BP level were about two-fold higher than in control plants.
